Impact damage resistance and post impact tolerance of optimum banana-pseudo stem fiber reinforced epoxy sandwich structures

Banana fiber has a high potential for use in fiber composite structures due to its promise as a polymer reinforcement. However, it has poor bonding characteristics with the matrixes due to hydrophobic-hydrophilic incompatibility, inconsistency in blending weight ratio, and fiber length instability. In this study, the optimal conditions for a banana/epoxy composite as determined previously were used to fabricate a sandwich structure where carbon/Kevlar twill plies acted as the skins. The structure was evaluated based on two experimental tests: low-velocity impact and compression after impact (CAI) tests. Here, the synthetic fiber including Kevlar, carbon, and glass sandwich structures were also tested for comparison purposes. In general, the results showed a low peak load and larger damage area in the optimal banana/epoxy structures. The impact damage area, as characterized by the dye penetration, increased with increasing impact energy. The optimal banana composite and synthetic fiber systems were proven to offer a similar residual strength and normalized strength when higher impact energies were applied. Delamination and fracture behavior were dominant in the optimal banana structures subjected to CAI testing. Finally, optimization of the compounding parameters of the optimal banana fibers improved the impact and CAI properties of the structure, making them comparable to those of synthetic sandwich composites

Modification of RBD palm kernel and RBD palm stearin oil with ZDDP additive addition

Vegetable oils have gained worldwide concern due to environmental issues since it is biodegradable, renewable and environmental-friendly. However, the limitations of vegetable oils such as having low oxidation stability and poor low temperature properties need to be solved. The purpose of this paper is to evaluate the tribological behavior of refined, bleached and deodorized (RBD) palm kernel and RBD palm stearin by using a modified pin-on-disc tester. The influence of an anti-wear/extreme pressure (AW/EP) additive on the anti-friction and anti-wear characteristics was also evaluated. The experiment was carried out by varying zinc-dialkyl-dithiophosphate (ZDDP) additive concentration of 1wt%, 3wt% and 5wt%; load of 1kg, sliding speed of 2.5 m/s, test duration of 60 minutes and at room temperature. The findings have revealed that without an additive, RBD palm kernel and RBD palm stearin have high friction coefficient and wear as compared with synthetic oils. The addition of additives helps in the improvement of tribological performance of tested vegetable oils. It can be concluded that vegetable oils have a great potential to be used as a petroleum-based substitute

Fuzzy Logic Based Self-Adaptive Handover Algorithm for MobileWiMAX.

It is well known that WiMAX is a broadband technology that is capable of delivering triple play (voice, data, and video) services. However, mobility in WiMAX system is still a main issue when the mobile station (MS) moves across the base station (BS) coverage and be handed over between BSs. Among the challenging issues in mobile WiMAX handover are unnecessary handover, handover failure and handover delay, which may affect real-time applications. The conventional handover decision algorithm in mobile WiMAX is based on a single criterion, which usually uses the received signal strength indicator (RSSI) as an indicator, with the other fixed handover parameters such as handover threshold and handover margin. In this paper, a fuzzy logic based self-adaptive handover (FuzSAHO) algorithm is introduced. The proposed algorithm is derived from the self-adaptive handover parameters to overcome the mobile WiMAX ping-pong handover and handover delay issues. Hence, the proposed FuzSAHO is initiated to check whether a handover is necessary or not which depends on its fuzzy logic stage. The proposed FuzSAHO algorithm will first self-adapt the handover parameters based on a set of multiple criteria, which includes the RSSI and MS velocity. Then the handover decision will be executed according to the handover parameter values. Simulation results show that the proposed FuzSAHO algorithm reduces the number of ping-pong handover and its delay. When compared with RSSI based handover algorithm and mobility improved handover (MIHO) algorithm, respectively, FuzSAHO reduces the number of handovers by 12.5 and 7.5 %, respectively, when the MS velocity is <17 m/s. In term of handover delay, the proposed FuzSAHO algorithm shows an improvement of 27.8 and 8 % as compared to both conventional and MIHO algorithms, respectively. Thus, the proposed multi-criteria with fuzzy logic based self-adaptive handover algorithm called FuzSAHO, outperforms both conventional and MIHO handover algorithms

Characterization of industrial by-products as asphalt paving material

Most of the recent research is focusing on the utilization of industrial by-products in road construction. The intention is not only to mitigate the problem of waste being dumped to the landfills but to encourage their use as construction material without compromising quality and performance of the road. Steel slag and bottom ash are the industrial by-products generated in large quantity by industry. This study investigates the characteristics of steel slag and bottom ash to be utilized as aggregate in asphalt pavement. Both materials were characterized in terms of physical, chemical and morphological characteristics compared to the conventional granite aggregate. The results revealed that both materials have much potential to be used as aggregate in asphalt mix. The bottom ash was observed weaker in terms of strength, but the steel slag was found much stronger than the granite. The morphological structure of bottom ash and steel slag disclosed that these are made up of porous and rough-edged granular particles with slightly higher water absorption

Aquilaria species as potential anti-inflammatory agents–A review on in vitro and in vivo studies

141-154In the current review article, the studies conducted to investigate the anti-inflammatory activity of Aquilaria species are compiled and summarized. Since inflammation is the underlying cause of many diseases, the encounter of effective and safe biomedical anti-inflammatory compounds has become the focus of recent researches. Aquilaria species were known to possess a wide spectrum of pharmacological activities, among which anti-inflammatory activity has been reported in many in vitro and in vivo studies. Chromones, sesquiterpenoids, flavonoids, benzophenones and phorbol esters were the major anti-inflammatory compounds isolated from Aquilaria species. The objective of this review paper is to extend researches on the anti-inflammatory activity of different parts of Aquilaria species and support their future use in natural pharmaceutical preparations for the treatment of inflammation-associated conditions

Intertwining the arts and sciences to stimulate a creative mind

From the basic motion of a simple pendulum, which acts as a tool that turns a blank canvas into pure abstract art, this particular concept has been applied to science-related art to showcase its tremendous impact on scientific, psychological and educational fields. The Art and Science Program is a collaborative artistic program between the committees from the Chemical and Energy School of Engineering, UTM, and Sekolah Tun Fatimah (STF), with the aim of examining the impacts of the rotational motion of the pendulum which can generate mesmerizing art on blank mahjong papers. The outcome of the art has been influenced by various factors, such as the viscosity of the paint used, the flowrate of the paint drip, the velocity of the paint-pendulum-modelled dripper, the position of the release point, and the motion of the dripper arising from the resultant force of multiple interacting forces. By showing the interconnections between pendulum motion, gravitational force, potential and kinetic energies, and the fundamentals of fluid dynamics, artistic abstract paintings can be created from the science of mechanics. Intertwining the arts and sciences that has been the main focus of this program can garner greater appreciation, even embraced, as it results in a significant effect on the development of both creative and critical thinking among the participants and committees

Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial

Background: The EMPA KIDNEY trial showed that empagliflozin reduced the risk of the primary composite outcome of kidney disease progression or cardiovascular death in patients with chronic kidney disease mainly through slowing progression. We aimed to assess how effects of empagliflozin might differ by primary kidney disease across its broad population. Methods: EMPA-KIDNEY, a randomised, controlled, phase 3 trial, was conducted at 241 centres in eight countries (Canada, China, Germany, Italy, Japan, Malaysia, the UK, and the USA). Patients were eligible if their estimated glomerular filtration rate (eGFR) was 20 to less than 45 mL/min per 1·73 m2, or 45 to less than 90 mL/min per 1·73 m2 with a urinary albumin-to-creatinine ratio (uACR) of 200 mg/g or higher at screening. They were randomly assigned (1:1) to 10 mg oral empagliflozin once daily or matching placebo. Effects on kidney disease progression (defined as a sustained ≥40% eGFR decline from randomisation, end-stage kidney disease, a sustained eGFR below 10 mL/min per 1·73 m2, or death from kidney failure) were assessed using prespecified Cox models, and eGFR slope analyses used shared parameter models. Subgroup comparisons were performed by including relevant interaction terms in models. EMPA-KIDNEY is registered with ClinicalTrials.gov, NCT03594110. Findings: Between May 15, 2019, and April 16, 2021, 6609 participants were randomly assigned and followed up for a median of 2·0 years (IQR 1·5–2·4). Prespecified subgroupings by primary kidney disease included 2057 (31·1%) participants with diabetic kidney disease, 1669 (25·3%) with glomerular disease, 1445 (21·9%) with hypertensive or renovascular disease, and 1438 (21·8%) with other or unknown causes. Kidney disease progression occurred in 384 (11·6%) of 3304 patients in the empagliflozin group and 504 (15·2%) of 3305 patients in the placebo group (hazard ratio 0·71 [95% CI 0·62–0·81]), with no evidence that the relative effect size varied significantly by primary kidney disease (pheterogeneity=0·62). The between-group difference in chronic eGFR slopes (ie, from 2 months to final follow-up) was 1·37 mL/min per 1·73 m2 per year (95% CI 1·16–1·59), representing a 50% (42–58) reduction in the rate of chronic eGFR decline. This relative effect of empagliflozin on chronic eGFR slope was similar in analyses by different primary kidney diseases, including in explorations by type of glomerular disease and diabetes (p values for heterogeneity all &gt;0·1). Interpretation: In a broad range of patients with chronic kidney disease at risk of progression, including a wide range of non-diabetic causes of chronic kidney disease, empagliflozin reduced risk of kidney disease progression. Relative effect sizes were broadly similar irrespective of the cause of primary kidney disease, suggesting that SGLT2 inhibitors should be part of a standard of care to minimise risk of kidney failure in chronic kidney disease. Funding: Boehringer Ingelheim, Eli Lilly, and UK Medical Research Council

Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study

Background Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to inform future public health strategies. Methods For this cross-sectional study, we assessed children and adolescents younger than 18 years with a clinical or genetic diagnosis of HeFH at the time of entry into the Familial Hypercholesterolaemia Studies Collaboration (FHSC) registry between Oct 1, 2015, and Jan 31, 2021. Data in the registry were collected from 55 regional or national registries in 48 countries. Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded from the registry; people with untreated LDL cholesterol (LDL-C) of at least 13·0 mmol/L were excluded from this study. Data were assessed overall and by WHO region, World Bank country income status, age, diagnostic criteria, and index-case status. The main outcome of this study was to assess current identification and management of children and adolescents with familial hypercholesterolaemia. Findings Of 63 093 individuals in the FHSC registry, 11 848 (18·8%) were children or adolescents younger than 18 years with HeFH and were included in this study; 5756 (50·2%) of 11 476 included individuals were female and 5720 (49·8%) were male. Sex data were missing for 372 (3·1%) of 11 848 individuals. Median age at registry entry was 9·6 years (IQR 5·8–13·2). 10 099 (89·9%) of 11 235 included individuals had a final genetically confirmed diagnosis of familial hypercholesterolaemia and 1136 (10·1%) had a clinical diagnosis. Genetically confirmed diagnosis data or clinical diagnosis data were missing for 613 (5·2%) of 11 848 individuals. Genetic diagnosis was more common in children and adolescents from high-income countries (9427 [92·4%] of 10 202) than in children and adolescents from non-high-income countries (199 [48·0%] of 415). 3414 (31·6%) of 10 804 children or adolescents were index cases. Familial-hypercholesterolaemia-related physical signs, cardiovascular risk factors, and cardiovascular disease were uncommon, but were more common in non-high-income countries. 7557 (72·4%) of 10 428 included children or adolescents were not taking lipid-lowering medication (LLM) and had a median LDL-C of 5·00 mmol/L (IQR 4·05–6·08). Compared with genetic diagnosis, the use of unadapted clinical criteria intended for use in adults and reliant on more extreme phenotypes could result in 50–75% of children and adolescents with familial hypercholesterolaemia not being identified. Interpretation Clinical characteristics observed in adults with familial hypercholesterolaemia are uncommon in children and adolescents with familial hypercholesterolaemia, hence detection in this age group relies on measurement of LDL-C and genetic confirmation. Where genetic testing is unavailable, increased availability and use of LDL-C measurements in the first few years of life could help reduce the current gap between prevalence and detection, enabling increased use of combination LLM to reach recommended LDL-C targets early in life. Funding Pfizer, Amgen, Merck Sharp & Dohme, Sanofi–Aventis, Daiichi Sankyo, and Regeneron