46,026 research outputs found
On the Redshift Distribution of Gamma Ray Bursts in the Swift Era
A simple physical model for long-duration gamma ray bursts (GRBs) is used to
fit the redshift (z) and the jet opening-angle distributions measured with
earlier GRB missions and with Swift. The effect of different sensitivities for
GRB triggering is sufficient to explain the difference in the z distributions
of the pre-Swift and Swift samples, with mean redshifts of ~1.5 and
~2.7, respectively. Assuming that the emission properties of GRBs do not
change with time, we find that the data can only be fitted if the comoving
rate-density of GRB sources exhibits positive evolution to z >~ 3-5. The mean
intrinsic beaming factor of GRBs is found to range from ~34-42, with the Swift
average opening half-angle ~10 degree, compared to the pre-Swift
average of ~7 degree. Within the uniform jet model, the GRB
luminosity function is proportional to L^{-3.25}_*, as inferred from our best
fit to the opening angle distribution. Because of the unlikely detection of
several GRBs with z <~ 0.25, our analysis indicates that low redshift GRBs
represent a different population of GRBs than those detected at higher
redshifts. Neglecting possible metallicity effects on GRB host galaxies, we
find that ~1 GRB occurs every 600,000 yrs in a local L_* spiral galaxy like the
Milky Way. The fraction of high-redshift GRBs is estimated at 8-12% and 2.5-6%
at z >= 5 and z >= 7, respectively, assuming continued positive evolution of
the GRB rate density to high redshifts.Comment: Accepted for publication in ApJ. The paper contains 29 pages and 24
figure
Characterization of the Influences of Human Cytomegalovirus Glycoprotein O (gO) Expression on gH/gL Complexes Assembly and Its Polymorphisms on Cell-free and Cell-to-cell Spread, and Antibody Neutralization.
Human cytomegalovirus (HCMV) is widely spread throughout the world and immunocompromised individuals can suffer severe diseases from HCMV infection. Once the infection is established, HCMV can spread through the body and infect many major somatic cell types. The glycoproteins H and L (gH/gL) on HCMV envelope can be bound by either gO or the UL128-131 proteins to form complexes gH/gL/gO and gH/gL/UL128-131 that are critical for viral entry and spread, and these two complexes are important targets of neutralizing antibodies. Strains of HCMV vary considerably in the levels of gH/gL/gO and gH/gL/UL128-131. gO is one of the most diverse loci among strains with 10-30% of amino acid sequence differences. In this thesis I explored the mechanisms behind the complex assembly differences between strains and the impacts of interstrain gO diversity on the biology of HCMV. My results uncovered that the strain variations in the assembly of gH/gL complexes is due to the differences in the expression level of gO and UL128-131, while gO amino acid sequence differences have no influence on the complexes assembly. Interestingly, the diversity of gO has dramatic impacts on HCMV cell-free and cell-to-cell spread as well as on antibody neutralization and these effects of gO polymorphisms are epistatically dependent on other variable loci in the virus genome. My study could help to understand the complexity of genotypes observed in clinical samples and decode the challenge for intervention approaches against HCMV
Sub-100 attoseconds optics-to-microwave synchronization
We use two fiber-based femtosecond frequency combs and a low-noise carrier
suppression phase detection system to characterize the optical to microwave
synchronization achievable with such frequency divider systems. By applying
specific noise reduction strategies, a residual phase noise as low as -120
dBc/Hz at 1 Hz offset frequency from a 11.55 GHz carrier is measured. The
fractional frequency instability from a single optical-to-frequency divider is
1.1E-16 at 1 s averaging down to below 2E-19 after only 1000 s. The
corresponding rms time deviation is lower than 100 attoseconds up to 1000 s
averaging duration.Comment: 4 pages, 3 figure
An ultrafast 1 x M all-optical WDM packet-switched router based on the PPM header address
This paper presents an all-optical 1 x M WDM router architecture for packet routing at multiple wavelengths simultaneously, with no wavelength conversion modules. The packet header address adopted is based on the pulse position modulation (PPM) format, thus enabling the use of only a singlebitwise optical AND gate for fast header address correlation. It offers multicast as well as broadcast capabilities. It is shown that a high speed packet routing at 160 Gb/s can be achieved with a low channel crosstalk (CXT) of ~ -27 dB at a channel spacing of greater than 0.4 THz and a demultiplexer bandwidth of 500 GHz
Privacy Year in Review: Canada's Personal Information and Protection and Electronic Documents Act and Japan's Personal Information Protection Act
Recommended from our members
Fine-Scale Variations in Eucritic Pyroxene FeO/MnO: Process vs. Provenance.
Most asteroidal igneous rocks are eucrite-like basalts and gabbros, composed mostly of ferroan low- and high-Ca pyroxenes and calcic plagioclase, plus smaller amounts of silica (most commonly tridymite), ilmenite, chromite, troilite, Ca-phosphate, metal and sometimes ferroan olivine. Eucrite-like mafic rocks are fragments of the crusts of differentiated asteroids, and most are likely from 4 Vesta
Fabrication and Characterizations of YSZ Electrolyte Films for SOFC
6th China International Conference on High-Performance Ceramics (CICC-6), Harbin, PEOPLES R CHINA, AUG 16-19, 2009 affiliation: Han, MF (Reprint Author), China Univ Min & Technol, Sch Chem & Environm Engn, Union Res Ctr Fuel Cell, Beijing 100083, Peoples R China. [Han, Min-Fang; Yang, Zhibin; Liu, Ze] China Univ Min & Technol, Sch Chem & Environm Engn, Union Res Ctr Fuel Cell, Beijing 100083, Peoples R China. keywords: SOFC; Yttria stabilized zirconia; electrolyte keywords-plus: ZIRCONIA; POWDERS; MICROSTRUCTURE; CONDUCTIVITY; CATHODE; GROWTH; ZRO2 subject-category: Materials Science, Ceramics; Materials Science, Composites author-email: [email protected] number-of-cited-references: 24 times-cited: 0 doc-delivery-number: BPZ23 unique-id: ISI:000280417300189Yttria stabilized zirconia (YSZ) has been widely used as electrolyte in solid oxide fuel cell (SOFC). The effect of fabrication process on the properties of YSZ electrolyte thick film is discussed in the paper. With YSZ nano-powders of about 20-60nm as raw material, YSZ green adobe was fabricated by tape calendering process. Three-step sintering process was performed firstly holding at 1000 degrees C for 2h, then raising to 1300 similar to 1400 degrees C, then decreasing to 1200 similar to 1300 degrees C within 30 minutes, and finally calcining at 1200 similar to 1300 degrees C for 5 similar to 20 hrs. Dense YSZs with relative density of 96-99% are obtained; the grain size of YSZ was reduced to 0.5-3 mu m. During the process of grain growth, there are both grain boundary diffusion and grain boundary migration. The feasibility of densification without grain growth relies on the suppression of grain boundary migration while keeping grain boundary diffusion active at a temperature as low as 1200 similar to 1300 degrees C. Whereas the electric conductivities of the YSZs are even higher than that obtained in conventional single step sintering process. The process is applied to the anode-supported SOFCs co-fired at 1250 similar to 1300 degrees C, and the cathode-supported SOFCs co-fired at 1200 similar to 1250 degrees C
Australopithecus afarensis endocasts suggest ape-like brain organization and prolonged brain growth
Human brains are three times larger, are organized differently, and mature for a longer period of time than those of our closest living relatives, the chimpanzees. Together, these characteristics are important for human cognition and social behavior, but their evolutionary origins remain unclear. To study brain growth and organization in the hominin species Australopithecus afarensis more than 3 million years ago, we scanned eight fossil crania using conventional and synchrotron computed tomography. We inferred key features of brain organization from endocranial imprints and explored the pattern of brain growth by combining new endocranial volume estimates with narrow age at death estimates for two infants. Contrary to previous claims, sulcal imprints reveal an ape-like brain organization and no features derived toward humans. A comparison of infant to adult endocranial volumes indicates protracted brain growth in A. afarensis, likely critical for the evolution of a long period of childhood learning in hominins
- …