A CLOSE POSITIVE ASSOCIATION BETWEEN OBESITY AND BLOOD PRESSURE IN RATS

The purpose of this study was to analyze how the effect of each increase in Body Mass Index (BMI) on the increase in blood pressure (BP). The research design was a laboratory experiment with 52 non-obese and obese rats as subjects (non-obese, n=14 and obese, n=38). Rats were induced obesity using a high-fat diet for four weeks. BMI used is based on the Lee Index with obesity indicators if 300 g/cm. Data analysis using independent sample t-test, simple linear regression test, and Pearson correlation test; (p0.05). The results: BP in non-obese rats was lower than obese rats (89.00±7.38 vs 190.11±4.42; p=0.001*), BMI was positively associated with BP (p=0.001*); an increase in BMI will increase BP (p=0.001*), there is a strong correlation between BMI and BP (r=0.977; p=0.001*). The regression equation (Y = 707.42 + 2.75 X) indicates that every 1 g/cm increase in BMI will be followed by an increase in BP of 2.75 mmHg. The analysis of R-square = 0.942 shows that the accuracy of the linear equation model is 94.2%. In conclusion, BMI has a strong positive correlation with BP, an increase in BMI will increase BP; obesity induces high blood pressure in rats

Losing Weight through Regular Exercise among Overweight/Obesity Women Aged 35-45 years

Exercise is a simple and low-cost way to lose weight, but many people have become apprehensive to provide it. This activity aims to shift the community’s lifestyle from sedentary to active by encouraging physical activity through frequent gymnastics. Darussalam housewives gathered near the Universitas Syiah Kuala campus. There were two groups of 20 people: regular participants (n=11) and non-regular participants (n=9). Everyone in the study was between the ages of 30-45. Participants’ body weight (BW), height, and Body Mass Index (BMI) were measured before and after treatment. Participants did 60 minutes of gymnastics modified from Zumba, Aerobic, and Salsa, 3–4 times per week, at 05.00–06.00 p.m, for 12 weeks (3 months), and without any special diet. The regular group’s average age was 35.3 years, whereas the non-regular group’s average age was 36.78 years. The results showed that 80 percent and 22.22 percent of participants in the regular and non-regular groups, respectively, lost weight. Before and after exercise, the regular group’s mean BW decreased by 3.65 kg (68.25 and 84.6 vs. 59.19 and 59.25 kg), while the non-regular group’s BW increased by 0.06 kg. The regular exercise group’s BMI dropped by 1.53 kg/m2 after gymnastics (28.45 and 26.92 vs. 27.01 and 27.01 kg/m2), while the non-regular exercise group’s BMI remained unchanged. Gymnastic movements have been modified to include Zumba, Aerobics, and Salsa, which could reduce BW and BMI. As a result, sustained exercise is required to help people reduce their risk of obesity. This practice has helped the government of the Republic of Indonesia’s efforts to increase physical activity and decrease the sedentary lifestyle in the population, thereby improving societal health. Obesity in women can be treated and prevented with regular exercise.

GROWTH INHIBITION AND INDUCTION OF APOPTOSIS IN MCF-7 AND T47D BREAST CANCER CELL LINES BY ETHANOL EXTRACT OF SEURAPOH (Chromolaena odorata) LEAVES

This study aims to determine the growth inhibition and apoptosis induction of MCF-7 and T47D cancer cells by ethanol extract of Chromolaena odorata leaves. A post-test with control group design was used in this study. The extract was made by maceration with 80%ethanol and the tested concentrations used were 7.80 µg/mL-500 µg/mL with standard drug doxorubicin ranged from 1.56 µg/mL-100 µg/mL.The growth inhibition was determined by the MTT colorimetry method, apoptosis induction by double staining using acridine orange-ethidiumbromide, and the existence of apoptosis was proven immunocytochemically through the expression of Bcl-2 proteins. The results showed that the growth inhibition of MCF-7 was 100.29%-28.19% and T47D was 100.37%-16.01%. The IC50 values of MCF-7 was 327.34 µg/mL and T47D was 135.16 µg/mL. The presence of apoptosis was marked by finding the morphological change of cells such as dead, necrosis, and chromatin condensation cells. This suggests that interventions with ethanol extract of Chromolaena odorata leaves can induce apoptosis that has been proven by reducing the expression of Bcl-2 proteins

LOSE WEIGHT AND PREVENT OBESITY BY AEROBIC GYMNASTICS

Aerobic gymnastics is a sport that is very popular in today's society, especially for those who want to lose or control body weight. But sports alone is not enough to lose weight and it must be coupled with good eating pattern settings. The problem is many of us are very difficult to control our diet and it needs to be analyzed further. This research aims to carry out an analysis of the influence of aerobic gymnastics to weight loss without diet interventions given.  The subject was 15 women, aged 20-25 years old, have a normal body weight. The intervention provided in the form of gymnastic aerobics three times a week, performed for 45-minutes practice session, and each was given for 1 month. This research was a quasi experimental research with one group pretest-posttest design. Weight measurement was done before and after aerobic gymnastics given. The results indicated that the aerobic gymnastics for 1 month losing 0.73% of body  weight, but the decline was not statistically meaningful. This showed that aerobic gymnastics for 1 month for women in the age 20-25 years has started to give response, but the duration has not been enough to lose significantly of body weight. It was concluded that in order to lose or control body weight, besides  takes aerobic gymnastics with the duration of up to 1 month, it has to accompany with  diet arrangement. This would give effect to  prevent  overweight and obesit

Pengaruh Pendekatan Active Learning Terhadap Hasil Belajar IPS Siswa Kelas Iv Mis Al-Iqra’ Medan Belawan

Tujuan penelitian ini adalah untuk mengetahui : 1) Hasil belajar siswa pada mata pelajaran IPS dengan penggunaan pendekatan Active Learning, 2) Hasil belajar siswa pada mata pelajaran IPS dengan penggunaan pendekatan konvensional, 3) pengaruh yang signifikan antara Pendekatan Active Learning terhadap hasil belajar siswa pada mata pelajaran IPS. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan Quasi Experiment (eksperimen semu). Populasi dan sampel dalam penelitian ini adalah siswa kelas IV yang terdiri dari 2 kelas berjumlah 40 siswa. Instrumen tes yang digunakan untuk mengetahui hasil belajar siswa adalah tes pilihan berganda berupa pre test dan post test sebanyak 10 soal yang telah validkan ke dosen ahli dan siswa. Analisis data yang digunakan yaitu t-test. Temuan penelitian ini sebagai berikut : 1) hasil belajar IPS pada kelas eksperimen (IVB) dengan menggunakan pendekatan Active Learning mata pelajaran IPS rata-rata post test 85. 2) hasil belajar IPS pada kelas kontrol (IVA) dengan menggunakan pendekatan konvensional mata pelajaran IPS rata-rata post test 66. Berdasarkan hasil rata-rata post test bahwa pembelajaran menggunakan pendekatan Active Learning memiliki hasil belajar yang lebih baik dibanding kelas kontrol. 3) berdasarkan uji statistik t pada data post test bahwa diperoleh pendekatan Active Learning berpengaruh signifikan terhadap hasil belajar siswa. Berdasarkan hasil perhitungan uji t diperoleh thitung > ttabel yaitu 5,097 > 2,024 (n=20) dengan taraf signifikan 0,05 atau 5% yang menyatakan bahwa Ha diterima dan H0 ditolak. Maka dapat disimpulkan bahwa pendekatan Active Learning berpengaruh signifikan terhadap hasil belajar IPS siswa kelas IV MIS Al-Iqra’ Medan Belawan

Manfaat Bakso Jantung Pisang untuk Ibu Menyusui

Breastmilk production runs smoothly. Breastfeeding mothers must eat sufficient nutrition. A good food ingredient for breastfeeding mothers is the banana heart because it contains galactagogue which can stimulate the hormones oxytocin and prolactin to increase milk production. The banana heart is also easily available by the community for daily use. To increase the consumption of banana blossoms in nursing mothers, it is processed into food in the form of meatballs. Meatballs are a national food that is popular with all people. The method of processing meatballs is also easy and provides many benefits for the health of the body. This research has the aim, benefits, of banana heart meatball for breastfeeding mother's milk production. This type of research is quasi-experimental with a pretest and posttest approach. A sample of 60 mothers breastfed for more than the first day in the working area of ​​Bone Bolango Health Center, Gorontalo. The sampling technique used purposive sampling. Measuring instruments used measuring cups and observation sheets. Before being given the treatment, the respondents' milk was given 100 grams of heart meatballs every day for 6 days. After that, it is measured again with a measuring cup and an observation sheet. The results of data analysis used paired t-test values ​​(p-value 0.001 <α = 0.05) in the breast milk production group in the case and treatment control groups. The result is an average increase in milk production after the 24 ml treatment.Produksi ASI supaya berjalan dengan lancar ibu menyusui harus mengkonsumsi makanan cukup gizi. Bahan makanan yang baik untuk ibu menyusui yaitu jantung pisang karena mengandung galaktagogue yang dapat menstimulasi hormon oksitoksin dan prolaktin untuk menambah produksi ASI. Jantung pisang juga mudah didapatkan oleh masyarakat untuk dikonsumsi sehari-hari. Untuk meningkatkan konsumsi jantung pisang pada ibu menyusui diolah menjadi makanan berupa bakso. Bakso merupakan makanan nasional yang banyak digemari oleh semua kalangan masyarakat. Cara pengolahan bakso juga mudah dan banyak memberikan manfaat bagi kesehatan tubuh. Penelitian ini mempunyai tujuan mengetahui manfaat bakso jantung pisang untuk produksi ASI ibu menyusui. Jenis penelitian quasi ekperimen dengan pendekatan pretest and posttest. Sampel 60 ibu menyusui hari pertama wilayah kerja Puskesmas Bone Bolango Gorontalo. Teknik sampling menggunakan purpossive sample. Alat ukur yang digunakan gelas ukur dan lembar observasi. Sebelum diberi perlakuan produksi ASI responden diukur kemudian diberikan bakso jantung pisang sebanyak 100gram setiap hari selama 6 hari. Setelah itu diukur kembali dengan gelas ukur dan lembar observasi. Hasil analisa data menggunakan paired t-test nilai (p-value 0,001<α=0,05) yang bermakna ada perbedaan produksi ASI pada kelompok percobaan dan pembanding sesudah perlakuan. Hasilnya rata-rata produksi ASI setelah diberikan perlakuan meningkat 24 ml

Pengaruh Pola Asuh Single Parent Terhadap Perilaku Seks Pranikah Remaja : studi kasus terhadap siswa SMA Negeri 10 Bandung

Seiring perkembangan zaman dan tranformasi budaya, baik budaya masa maupun budaya populer di masyarakat, hal ini berdampak terhadap banyaknya para remaja yang mengubah gaya hidupnya. Pada kenyataannya perubahan gaya hidup ini berdampak kepada meningkatnya perilaku menyimpang di masyarakat. Permasalahan yang diangkat dalam penelitian ini adalah semakin meningkatnya perilaku seks pranikah yang dilakukan oleh remaja di kota Bandung terutama siswa SMA, serta kurangnya pengawasan dari orang tua dalam mencegah perilaku ini. Penelitian ini dilakukan pada siswa SMA Negeri 10 Bandung yang memiliki orang tua single parent. Penelitian ini bertujuan untuk mengetahui gambaran pola asuh single parent yang diterapkan dan kondisi perilaku seks pranikah siswa serta adakah pengaruh dari pola asuh single parent terhadap perilaku seks pranikah remaja atau siswa di SMA Negeri 10 Bandung. Variabel yang diteliti dalam penelitian ini adalah pola asuh single parent dan perilaku seks pranikah remaja. Dimensi yang digunakan untuk pola asuh single parent ini adalah: pola asuh demokratis, permisif, dan otoriter, sedangkan dimensi perilaku seks pranikah remaja adalah bermesraan, bercumbu dan berhubungan kelamin. Penelitian ini menggunakan metode explanatory survey, teknik pengumpulan data dengan cara penyebaran angket (kuesioner). Instrumen yang digunakan adalah angket model skala Likert. Teknis analisis data yang digunakan adalah analisis regresi sederhana. Hasil penelitian menunjukkan : (1) Pola asuh permisif merupakan pola asuh yang paling dominan dalam pola asuh yang diterapkan oleh orang tua single parent pada siswa SMAN 10 Bandung, (2) Perilaku seks pranikah pada siswa SMAN 10 Bandung tergolong tinggi dimana memiliki rata-rata sebesar 2,77, (3) Terdapat pengaruh positif dan signifikan dari pola asuh single parent terhadap perilaku seks pranikah remaja. The development and transformation of culture, either mass or popular culture among society, result in changes in many adolescents’ lifestyles. In fact, the changes affect the increase of deviant behavior among society. Two problems proposed in this current study are the increase of adolescents’ premarital sex behavior committed by adolescents, particularly high school students in Bandung, and the lack of monitoring by parents to prevent this behavior. This study is conducted to 10 Senior High School students’ who have single parent parenting style. The aims of the study are to discover the pattern of single parent parenting style implemented by the parents and to discover the influence of single parent parenting style on Bandung 10 Senior High School students’ premarital sex behavior. The variable analyzed in the current study is single parent parenting style pattern and adolescents’ premarital sex behavior. The dimensions utilized for single parent parenting style are: democratic, permissive and authoritative styles. Meanwhile, the dimensions for adolescents’ premarital sex behavior are intimacy, flattery and sexual activity. This study employs explanatory survey method, which settles questionnaire to collect the data. Likert scale is utilised as the research instrument. The data is analyzed through simple regression analysis. The study reveals that : (1) Permissive style is the most dominant parenting style implemented by single parent of Bandung 10 Senior High School Bandung students, (2) The premarital sex behavior among the students is considered high in which it counts 2,77 on average, (3) There is positive and significant influence of single parent parenting pattern on adolescents’ premarital sex behavior

PEMANFAATAN LAHAN PERBUKITAN UNTUK USAHATANI TANAMAN JAMBU METE (Annacardium Occidentale L ) DI DESA KARANGTENGAH KECAMATAN IMOGIRI KABUPATEN BANTUL YOGYAKARTA

Penelitian ini dilakukan di Desa Karangtengah, tujuan penelitian ini adalah untuk mengetahui: (1) Kesesuaian kondisi fisik dengan syarat tumbuh tanaman jambu mete, (2) Pengelolaan usahatani jambu mete, (3) Hambatan –hambatan usahatani di daerah penelitian, (4) roduktivitas usahatani tanaman jambu mete di Desa Karangtengah. Penelitian ini merupakan penelitian deskriptif kuantitatif, populasi dalam penelitian ini yaitu seluruh petani yang mengusahakan jambu mete di Desa Karangtengah, yang berjumlah 42 responden. Teknik pengumpulan data dilakukan dengan observasi, wawancara dan pengumpulan data sekunder. Teknik pengolahan data meliputi editing, koding dan tabulasi. Teknik analisis data dengan menggunakan tabel frekuensi satu arah. Hasil penelitian ini menunjukkan bahwa: (1) Kondisi fisik lahan di daerah penelitian sesuai untuk budidaya tanaman jambu mete, kondisi topografi, iklim dan tanah di daerah penelitian sesuai dengan syarat tumbuh tanaman jambu mete. (2) Kondisi non fisik yang terkait dengan usahatani jambu mete meliputi: modal, tenaga kerja, transportasi, pemasaran, dan sumber pengetahuan. (3) Pengolahan usahatani jambu mete meliputi: pengelolaan lahan, penentuan jarak tanam,pembuatan lubang tanam, pengadaan bibit, penanaman, pemupukan, pengairan,pemberantasan hama dan penyakit, panen dan perlakuan pasca panen, (4) Hambatan – hambatan usahatani jambu mete di daerah penelitian antara lain: modal yang terbatas, kurangnya jaringan pemasaran, serangan hama dan penyakit. (5) Produktivitas jambu mete di daerah penelitian bervariasi berkisar antara 201 –400 kg/m2 /thn, dengan rata – rata 236,309 kg/m2 /thn. Rata – rata pendapatan bersih yang diperoleh petani di Desa Karangtengah adalah Rp. 8.638.559/tahun. Kata Kunci: Usahatani, Jambu Met