150 research outputs found

    Vermont Global Warming Solutions Act: The Costs of Inaction from Land Conversions

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    The Vermont (VT) Global Warming Solutions Act (GWSA, 2020) sets greenhouse gas (GHG) emissions reduction targets as 26% below 2005 by 2025, 40% below 1990 by 2030 and 80% below 1990 by 2050 for energy-related emissions only. Vermont’s omission of GHG emissions from land conversions can result in significant costs of inaction (COI), which can hinder state’s mitigation and adaptation plans and result in a climate crisis-related risks (e.g., credit downgrade). Science-based spatio-temporal data of GHG emissions from soils as a result of land conversions can be integrated into the conceptual framework of “action” versus “inaction” to prevent GHG emissions. The application of soil information data and remote sensing analysis can identify the GHG emissions from land conversions, which can be expressed as “realized” social costs of “inaction”. This study demonstrates the rapid assessment of the value of regulating ecosystems services (ES) from soil organic carbon (SOC), soil inorganic carbon (SIC), and total soil carbon (TSC) stocks, based on the concept of the avoided social cost of carbon dioxide (CO2) emissions for VT by soil order and county using remote sensing and information from the State Soil Geographic (STATSGO) and Soil Survey Geographic Database (SSURGO) databases. Classified land cover data for 2001 and 2016 were downloaded from the Multi-Resolution Land Characteristics Consortium (MRLC) website. These results provide accurate and quantitative spatio-temporal information about likely GHG emissions, which can be linked to VT’s climate action plan. A failure to considerably reduce emissions from land conversions in the future may need even larger reductions in the future and would increase climate change costs to VT and beyond its borders

    A study of Anthony Philip Heinrich, an American composer

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    During the past several decades many fine studies on early American composers have been undertaken. One of the most significant of these is William Treat Upton's biography of Anthony Philip Heinrich, a native of Bohemia but as much a son of his adopted country as George Washington or Abraham Lincoln. Upton's thorough, sympathetic, and highly entertaining account of Heinrich's rich and varied life suggests many further rewarding investigations of the countless manuscripts Heinrich left as his legacy to America. Most of these manuscripts are in the music collection of the Library of Congress and are easily obtainable on microfilm

    Choral and general music teaching techniques used in eighteen North Carolina junior high schools, spring, 1966

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    In this study of practical teaching techniques and procedures used in junior high school choral and general music classes, twenty-four teachers were observed in eighteen schools representing eight cities of the Greensboro, North Carolina area. Sixteen teachers were recommended by individuals prominent in the field of music education, five were recommended by music teachers observed in the study, and two were visited because of their location in Greensboro. The main purpose of the study is to examine teaching techniques currently used in junior high school choral and general music programs. The principal method for securing this information was direct observation. In addition, other data were secured through questionnaires completed by students and teachers, and interviews with teachers

    Presynaptic Protein Synthesis Is Required for Long-Term Plasticity of GABA Release

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    Long-term changes of neurotransmitter release are critical for proper brain function. However, the molecular mechanisms underlying these changes are poorly understood. While protein synthesis is crucial for the consolidation of postsynaptic plasticity, whether and how protein synthesis regulates presynaptic plasticity in the mature mammalian brain remain unclear. Here, using paired whole-cell recordings in rodent hippocampal slices, we report that presynaptic protein synthesis is required for long-term, but not short-term, plasticity of GABA release from type 1 cannabinoid receptor (CB1)-expressing axons. This long-term depression of inhibitory transmission (iLTD) involves cap-dependent protein synthesis in presynaptic interneuron axons, but not somata. Translation is required during the induction, but not maintenance, of iLTD. Mechanistically, CB1 activation enhances protein synthesis via the mTOR pathway. Furthermore, using super-resolution STORM microscopy, we revealed eukaryotic ribosomes in CB1-expressing axon terminals. These findings suggest that presynaptic local protein synthesis controls neurotransmitter release during long-term plasticity in the mature mammalian brain

    The Relationship of the Characteristics of Feedlot Pens to the Percentage of Cattle Shedding \u3ci\u3eEscherichia coli\u3c/i\u3e O157:H7 Within the Pen

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    This study was designed to discover relationships between characteristics of feedlot pens and the percentage of cattle shedding Escherichia coli O157:H7. Twenty-nine pens from five Midwestern feedlots were each sampled once between June and September, 1999. Feces were collected from all cattle in each pen. E. coli O157:H7 was isolated from the feces of 714 of 3162 cattle tested (23%), including at least one animal from each of the 29 pens. Pen prevalence did not differ between feedyards, but did vary widely within feedyards. Muddy pens were more likely to have a higher pen prevalence than normal pens

    Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity

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    Long-term modifications of neuronal connections are critical for reliable memory storage in the brain. However, their locus of expression—pre- or postsynaptic—is highly variable. Here we introduce a theoretical framework in which long-term plasticity performs an optimization of the postsynaptic response statistics toward a given mean with minimal variance. Consequently, the state of the synapse at the time of plasticity induction determines the ratio of pre- and postsynaptic modifications. Our theory explains the experimentally observed expression loci of the hippocampal and neocortical synaptic potentiation studies we examined. Moreover, the theory predicts presynaptic expression of long-term depression, consistent with experimental observations. At inhibitory synapses, the theory suggests a statistically efficient excitatory-inhibitory balance in which changes in inhibitory postsynaptic response statistics specifically target the mean excitation. Our results provide a unifying theory for understanding the expression mechanisms and functions of long-term synaptic transmission plasticity
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