Comparative effects of mulligan’s mobilization and proprioceptive neuromuscular facilitation technique on pain and disability in patients with sacroiliac joint dysfunction

Purpose: To evaluate the efficacy of Mulligan’s Movement of Mobilization and contract- relax technique on pain and disability in patients suffering from sacroiliac joint Dysfunction. Method: A randomized clinical trial was done at DHQ hospital Jhang. 38 persons including both genders old enough 20-35 years were associated with this review who meet the inclusion criteria were recruited by consecutive sampling technique and allocated to the groups by simple random sampling process and by sealed opaque enveloped labeled as 0 for group A and 1 for group B and indiscriminately allocated into two sets. One set A was specified to mulligan mobilization technique and the second set B was specified to contract-relax technique for 6 weeks as three sessions per week. Baseline treatment of hot pack and ultrasound was given to both groups. All the patients were assessed for pain with NPRS and for disability with MOPDQ before and after treatment. Data was analyzed using SPSS 22. Results: After treatment, both groups significantly improved in terms of pain and disability. Mean value of NPRS was reduced from 6.89±1.15 to 1.68±.58 in MWM Group while in Contract-Relax from 6.78±1.18 to 2.57±.90. Mean Value of MOPDQ improved from 31.00±6.24 to 2.95±.911 and 32.26±7.14 to 4.31±1.20 in MWM and Contract-Relax group. However, group that received mulligan technique had significantly better improved NPRS and MOPDQ values than contract-relax group in patients with Sacro-iliac dysfunction (p<0.05). Conclusion: In the management of sacroiliac joint dysfunction, Mulligan mobilization is more efficient than contract-relax approach

ASPECTS and Functional Outcomes in Left versus Right Hemisphere Strokes: A Prospective Cohort Study

Background: Stroke presents as the second most prominent factor contributing to global mortality. Immediate brain imaging can be valuable for assessing functional recovery potential. This study investigated the association between Alberta Stroke Program Early CT Score (ASPECTS) and functional outcomes in patients with left and right-hemisphere strokes. Methods: A prospective cohort study was conducted in July-Dec2 022, at a tertiary care hospital in Karachi including patients of either gender presenting within 2 days of stroke while excluding posterior circulation strokes, TIA & unwilling patients using a non-probability consecutive sampling technique. A total of 152 patients with acute ischemic stroke involving anterior circulation were analyzed and patients were categorized into two groups: the left hemisphere group (n=76) and the right hemisphere group (n=76) accordingly. ASPECTS scores were calculated from brain CT scans, while functional outcomes were measured using the modified Rankin Scale (mRS) at the three-month mark. Descriptive analysis and chi-square test were applied using SPSS vr25. Results: Patients (n=152) had a mean age of 61.75 ± 13 years, with males comprising 67% of the cohort. ASPECTS scores were notably higher in left hemisphere strokes (median 9, IQR 2) than right hemisphere strokes (median 8, IQR 3) (p=0.036). Higher ASPECTS scores (≥7) correlated with improved outcomes (mRS ≤2) in both hemispheres. There was no statistically significant difference in both groups’ functional outcomes (p=0.182). Conclusion: ASPECTS predicts functional outcomes in acute ischemic strokes equally well regardless of the affected hemisphere

Traditional medicinal plants used for respiratory disorders in Pakistan: a review of the ethno-medicinal and pharmacological evidence

Abstract Respiratory disorders are a common cause of malady and demise in Pakistan due to its remoteness, cold and harsh climatic conditions as well as scarce health care facilities. The people rely upon the indigenous plant resources to cure various respiratory disorders. The primary objective of this review was to assemble all available ethno-medicinal data of plants used for respiratory disorders in Pakistan. Pharmacological activity of these plants (based upon published scientific research), distribution, diversity, use, preparation methods, economical value, conservation status and various available herbal products of some plants have also been explored. This study scrutinized various electronic databases for the literature on medicinal plants used in Pakistan to treat respiratory disorders. A total of 384 species belonging to 85 families used to treat respiratory disorders in Pakistan has been documented. Cough was the disorder treated by the highest number of species (214) followed by asthma (150), cold (57) and bronchitis (56). Most of the plants belongs to Asteraceae (32) and Solanaceae family (32) followed by moraceae (17), Poaceae (13), and Amaranthaceae (13) with their habit mostly of herb (219) followed by Shrub (112) and tree (69). Traditional healers in the region mostly prepare ethno medicinal recipes from leaves (24%) and roots (11%) in the form of decoction. Among the reported conservation status of 51 plant species, 5 were endangered, 1 critically endangered, 11 vulnerable, 14 rare, 16 least concern, 3 infrequent and 1 near threatened. We found only 53 plants on which pharmacological studies were conducted and 17 plants being used in herbal products available commercially for respiratory disorders. We showed the diversity and importance of medicinal plants used to treat respiratory disorders in the traditional health care system of Pakistan. As such disorders are still causing several deaths each year, it is of the utmost importance to conduct phytochemical and pharmacological studies on the most promising species. It is also crucial to increase access to traditional medicine, especially in rural areas. Threatened species need special attention for traditional herbal medicine to be exploited sustainably

Indigenous medicinal plants of Pakistan used to treat skin diseases: a review

Abstract Ethno-pharmacological relevance Plants are providing reliable therapy since time immemorial. Pakistan has a great diversity in medicinal flora and people use these ethno-medicines to deal with many skin problems. This review explores the fundamental knowledge on various dermatological properties of medicinal plants of Pakistan and is aimed to provide a baseline for the discovery of new plants having activities against skin issues. Material and method A total of 244 published articles were studied using different research engines like PubMed, Google, Google-scholar and science direct. Results Review of literature revealed ethno-pharmacological use of 545 plant species, belonging to 118 families and 355 genera, to combat various skin ailments. Out of these, ten most commonly used plant species belonging to ten different families are documented in this review. It was also found out that ehno-medicines are prepared using various parts of the plants including leaves (28.32%), whole plant and roots 13.17% and 10.97% respectively, in the form of powder (23.5%) and paste (22.75%). A total of 13 endangered plant species and ten commercially important plants were recorded. Conclusion Medicinal plants of Pakistan have therapeutic effects against several skin problems; however most of medicinal plants are still not evaluated scientifically to support their ethno-pharmacological claim on skin. Dermatological pathogens are recommended to study. Further, the conservational programs should be established for endangered species