Selected aspects of lunar mare geology from Apollo orbital photography

Crater size-frequency distributions were studied (100-500 m) and are shown to provide significant integrated information concerning mare surface ages, subsurface stratigraphy, and surficial geology. Equilibrium cratering is discussed gradually reducing the relative numbers of craters smaller than 300-400 m in diameter as surfaces age and regolith thickens. Results for surface ages are in good agreement with other published crater ages. The existing correlations of large ring structures among various circular mare basins are shown to be based on criteria that are inconsistent and nonstandardized. A means of comparing equivalent ring structures in the different maria is proposed which takes into account the important characteristics of young unflooded basins (Orientale) as well as the progressive development of tectonic and volcanic features within the older flooded maria. Specific geologic aspects of several of the lunar maria are discussed and especially Mare Smythii, because of its great age and significantly different surface morphology. Lunar photographs and maps are shown

Interpersonal Trauma, Posttraumatic Stress and Depression

Dating aggression is common among emerging adults, and women who experience aggression from a dating partner are at risk for elevated depression and posttraumatic stress (Dutton et al., 2006). Although some women end their relationships as a result of aggression, other women remain committed to their partner, and aggression tends to escalate over time. The current study explored the role that depression and posttraumatic stress play in ending aggressive dating relationships as well as changes in these symptoms after ending such a relationship. The current study also sought to identify factors predictive of individual differences in emerging adults\u27 commitment to their aggressive dating relationships. A sample of 148 emerging adult women currently in an aggressive dating relationship completed questionnaires about themselves and their relationship; measures of rejection sensitivity, self-worth, and romantic relational style were included as predictors of the Investment Model variables (e.g., investment, satisfaction, quality of alternatives, and commitment; Rusbult, 1980). Two assessments were completed six months apart. Neither depression nor posttraumatic stress predicted ending an aggressive relationship. However, ending an aggressive relationship was associated with experiencing less physical aggression, which mediated reductions in posttraumatic stress. A more avoidant romantic style indirectly predicted commitment through relationship satisfaction and investment. Both commitment and rejection sensitivity significantly predicted continuing an aggressive relationship six months later

Physical activity as a tool for preventing and treating depression: Lessons learned from the COVID‐19 pandemic

Physical activity (PA) is understood to be important for the prevention and treatment of depression, however, less is known about the effects of withdrawal from PA on mood. Here we consider evidence published since the outbreak of the SARS‐CoV‐2 virus to assess the impact of the COVID‐19 pandemic on PA patterns and to evaluate whether engagement in PA in the context of the pandemic had an impact on depression vulnerability. During the initial stages of the pandemic and consequent lockdowns, there were global decreases in PA, with women, ethnic minorities, lower‐education, lower‐income, younger, and elderly people displaying more marked reductions in PA. Less PA was associated with a higher risk of experiencing moderate‐to‐severe depression symptoms, particularly for those who decreased their PA levels compared to pre‐pandemic. Both PA and sedentary behavior were independently associated with depression, such that low activity and high amounts of sitting both increased the likelihood of clinically significant symptoms. We also consider the role social connection during movement; while both in‐person and online PA can foster a sense of belonging, there is some evidence that socially distant, pandemic‐safe movement might disincentivise certain groups such as older adults and experienced exercisers from participating in PA. We conclude with several implications for prospective public health communications regarding PA, especially in the event of another global pandemic

The Use of Mobility Data for Responding to the COVID-19 Pandemic

As the COVID-19 pandemic continues to upend the way people move, work, and gather, governments, businesses, and public health researchers have looked increasingly at mobility data to support pandemic response. This data, assets that describe human location and movement, generally has been collected for purposes directly related to a company's business model, including optimizing the delivery of consumer services, supply chain management or targeting advertisements. However, these call detail records, smartphone-mobility data, vehicle-derived GPS, and other mobility data assets can also be used to study patterns of movement. These patterns of movement have, in turn, been used by organizations to forecast disease spread and inform decisions on how to best manage activity in certain locations.Researchers at The GovLab and Cuebiq, supported by the Open Data Institute, identified 51 notable projects from around the globe launched by public sector and research organizations with companies that use mobility data for these purposes. It curated five projects among this listing that highlight the specific opportunities (and risks) presented by using this asset. Though few of these highlighted projects have provided public outputs that make assessing project success difficult, organizations interviewed considered mobility data to be a useful asset that enabled better public health surveillance, supported existing decision-making processes, or otherwise allowed groups to achieve their research goals.The report below summarizes some of the major points identified in those case studies. While acknowledging that location data can be a highly sensitive data type that can facilitate surveillance or expose data subjects if used carelessly, it finds mobility data can support research and inform decisions when applied toward narrowly defined research questions through frameworks that acknowledge and proactively mitigate risk. These frameworks can vary based on the individual circumstances facing data users, suppliers, and subjects. However, there are a few conditions that can enable users and suppliers to promote publicly beneficial and responsible data use and overcome the serious obstacles facing them.For data users (governments and research institutions), functional access to real-time and contextually relevant data can support research goals, even though a lack of data science competencies and both short and long-term funding sources represent major obstacles for this goal. Data suppliers (largely companies), meanwhile, need governance structures and mechanisms that facilitate responsible re-use, including data re-use agreements that define who, what, where, and when, and under what conditions data can be shared. A lack of regulatory clarity and the absence of universal governance and privacy standards have impeded effective and responsible dissemination of mobility for research and humanitarian purposes. Finally, for both data users and suppliers, we note that collaborative research networks that allow organizations to seek out and provide data can serve as enablers of project success by facilitating exchange of methods and resources, and closing the gap between research and practice.Based on these findings, we recommend the development of clear governance and privacy frameworks, increased capacity building around data use within the public sector, and more regular convenings of ecosystem stakeholders (including the public and data subjects) to broaden collaborative networks. We also propose solutions towards making the responsible use of mobility data more sustainable for longterm impact beyond the current pandemic. A failure to develop regulatory and governance frameworks that can responsibly manage mobility data could lead to a regression to the ad hoc and uncoordinated approaches that previously defined mobility data applications. It could also lead to disparate standards about organizations' responsibilities to the public

Development of New Tuberculosis Vaccines: A Global Perspective on Regulatory Issues

What are the regulatory challenges for testing and introducing investigative TB vaccines into countries where the disease is endemic

Neoliberalisation and 'lad cultures' in higher education

This paper links HE neoliberalisation and ‘lad cultures’, drawing on interviews and focus groups with women students. We argue that retro-sexist ‘laddish’ forms of masculine competitiveness and misogyny have been reshaped by neoliberal rationalities to become modes of consumerist sexualised audit. We also suggest that neoliberal frameworks scaffold an individualistic and adversarial culture among young people that interacts with perceived threats to men’s privilege and intensifies attempts to put women in their place through misogyny and sexual harassment. Furthermore, ‘lad cultures’, sexism and sexual harassment in higher education may be invisibilised by institutions to preserve marketability in a neoliberal context. In response, we ask if we might foster dialogue and partnership between feminist and anti-marketisation politics

Evaluating alcohol intoxication management services: the EDARA mixed-methods study

Background: Front-line health-care services are under increased demand when acute alcohol intoxication is most common, which is in night-time environments. Cities have implemented alcohol intoxication management services to divert the intoxicated away from emergency care. Objectives: To evaluate the effectiveness, cost-effectiveness and acceptability to patients and staff of alcohol intoxication management services and undertake an ethnographic study capturing front-line staff’s views on the impact of acute alcohol intoxication on their professional lives. Methods: This was a controlled mixed-methods longitudinal observational study with an ethnographic evaluation in parallel. Six cities with alcohol intoxication management services were compared with six matched control cities to determine effects on key performance indicators (e.g. number of patients in the emergency department and ambulance response times). Surveys captured the impact of alcohol intoxication management services on the quality of care for patients in six alcohol intoxication management services, six emergency departments with local alcohol intoxication management services and six emergency departments without local alcohol intoxication management services. The ethnographic study considered front-line staff perceptions in two cities with alcohol intoxication management services and one city without alcohol intoxication management services. Results: Alcohol intoxication management services typically operated in cities in which the incidence of acute alcohol intoxication was greatest. The per-session average number of attendances across all alcohol intoxication management services was low (mean 7.3, average minimum 2.8, average maximum 11.8) compared with the average number of emergency department attendances per alcohol intoxication management services session (mean 78.8), and the number of patients diverted away from emergency departments, per session, required for services to be considered cost-neutral was 8.7, falling to 3.5 when ambulance costs were included. Alcohol intoxication management services varied, from volunteer-led first aid to more clinically focused nurse practitioner services, with only the latter providing evidence for diversion from emergency departments. Qualitative and ethnographic data indicated that alcohol intoxication management services are acceptable to practitioners and patients and that they address unmet need. There was evidence that alcohol intoxication management services improve ambulance response times and reduce emergency department attendance. Effects are uncertain owing to the variation in service delivery. Limitations: The evaluation focused on health service outcomes, yet evidence arose suggesting that alcohol intoxication management services provide broader societal benefits. There was no nationally agreed standard operating procedure for alcohol intoxication management services, undermining the evaluation. Routine health data outcomes exhibited considerable variance, undermining opportunities to provide an accurate appraisal of the heterogenous collection of alcohol intoxication management services. Conclusions: Alcohol intoxication management services are varied, multipartner endeavours and would benefit from agreed national standards. Alcohol intoxication management services are popular with and benefit front-line staff and serve as a hub facilitating partnership working. They are popular with alcohol intoxication management services patients and capture previously unmet need in night-time environments. However, acute alcohol intoxication in emergency departments remains an issue and opportunities for diversion have not been entirely realised. The nurse-led model was the most expensive service evaluated but was also the most likely to divert patients away from emergency departments, suggesting that greater clinical involvement and alignment with emergency departments is necessary. Alcohol intoxication management services should be regarded as fledgling services that require further work to realise benefit. Future work: Research could be undertaken to determine if a standardised model of alcohol intoxication management services, based on the nurse practitioner model, can be developed and implemented in different settings. Future evaluations should go beyond the health service and consider outcomes more generally, especially for the police. Future work on the management of acute alcohol intoxication in night-time environments could recognise the partnership between health-care, police and ambulance services and third-sector organisations in managing acute alcohol intoxication. Trial registration: Current Controlled Trials ISRCTN63096364

Surface Meltwater Impounded by Seasonal Englacial Storage in West Greenland

The delivery of surface meltwater through englacial drainage systems to the bed of the Greenland Ice Sheet modulates ice flow through basal lubrication. Recent studies in Southeast Greenland have identified a perennial firn aquifer; however, there are few observations quantifying the input or residence time of water within the englacial system and it remains unknown whether water can be stored within solid ice. Using hourly stationary radar measurements, we present observations of englacial and episodic subglacial water in the ablation zone of Store Glacier in West Greenland. We find significant storage of meltwater in solid ice damaged by crevasses extending down to 48 m below the ice surface during the summer which is released or refrozen during winter. This is a significant hydrological component newly observed in the ablation zone of Greenland that could delay the delivery of meltwater to the bed, changing the ice dynamic response to surface meltwater.Publisher PDFPeer reviewe