Angle-Resolved Photoemission of Solvated Electrons in Sodium-Doped Clusters

Angle-resolved photoelectron spectroscopy of the unpaired electron in sodium-doped water, methanol, ammonia, and dimethyl ether clusters is presented. The experimental observations and the complementary calculations are consistent with surface electrons for the cluster size range studied. Evidence against internally solvated electrons is provided by the photoelectron angular distribution. The trends in the ionization energies seem mainly determined by the degree of hydrogen bonding in the solvent and the solvation of the ion core. The onset ionization energies of water and methanol clusters do not level off at small cluster sizes, but decrease slightly with increasing cluster size

Ocean Chlorophyll Studies from a U-2 Aircraft Platform

Chlorophyll gradient maps of large ocean areas were generated from U-2 ocean color scanner data obtained over test sites in the Pacific and Atlantic Oceans. The delineation of oceanic features using the upward radiant intensity relies on an analysis method which presupposes that radiation backscattered from the atmosphere and ocean surface can be properly modeled using a measurement made at 778 nm. An estimation of the chlorophyll concentration was performed by properly ratioing radiances measured at 472 nm and 548 nm after removing the atmospheric effects. The correlation between the remotely sensed data and in-situ surface chlorophyll measurements was validated in two sets of data. The results show that the correlation between the in-situ measured chlorophyll and the derived quantity is a negative exponential function and the correlation coefficient was calculated to be -0.965

Electron mean free path from angle-dependent photoelectron spectroscopy of aerosol particles

We propose angle-resolved photoelectron spectroscopy of aerosol particles as an alternative way to determine the electron mean free path of low energy electrons in solid and liquid materials. The mean free path is obtained from fits of simulated photoemission images to experimental ones over a broad range of different aerosol particle sizes. The principal advantage of the aerosol approach is twofold. Firstly, aerosol photoemission studies can be performed for many different materials, including liquids. Secondly, the size-dependent anisotropy of the photoelectrons can be exploited in addition to size-dependent changes in their kinetic energy. These finite size effects depend in different ways on the mean free path and thus provide more information on the mean free path than corresponding liquid jet, thin film, or bulk data. The present contribution is a proof of principle employing a simple model for the photoemission of electrons and preliminary experimental data for potassium chloride aerosol particles

Pennsylvania Folklife Vol. 18, No. 2

• The Swiss Bank House in Pennsylvania • Trance-Preaching in the United States • The Sleeping Preachers: An Historical Study of the Role of Charisma in Amish Society • A Central Chimney Continental Log House • The German Journalist and the Dunker Love-Feast • Christmas Customs: Folk-Cultural Questionnaire No. 10https://digitalcommons.ursinus.edu/pafolklifemag/1034/thumbnail.jp

Defective TGFβ signaling in bone marrow-derived cells prevents Hedgehog-induced skin tumors

Hedgehog (Hh) signaling in cancer cells drives changes in the tumor microenvironment that are incompletely understood. Here we report that Hh- driven tumors exhibit an increase in myeloid-derived suppressor cells (MDSC) and a decrease in T cells, indicative of an immune suppressive tumor microenvironment. This change was associated with activated TGFβ signaling in several cell types in BCCs. We determined that TGFβ signaling in bone marrow (BM)-derived cells, not keratinocytes, regulates MDSC and promotes tumor development. Tgfbr2 deficiency in the BM-derived cells also reduced the size of previously developed tumors in mice. We identified CCL2 as the major chemokine attracting MDSC to tumor, whose expression was Tgfbr2-dependent, whereas its receptor CCR2 was highly expressed in MDSC population. CCL2 alone was sufficient to induce migration of MDSC. Moreover, the CCR2 inhibitors prevented MDSC migration towards skin cells in vitro, reduced MDSC accumulation and Hh signaling-driven tumor development in mice. Our results reveal a signaling network critical for Hh signaling in cancer cells to establish an effective immune suppressive microenvironment during tumor development

Report of Feasibility Study Task Force for Marietta Truck Growers Association

Exact date of working paper unknown

Hydration dynamics at fluorinated protein surfaces

Water-protein interactions dictate many processes crucial to protein function including folding, dynamics, interactions with other biomolecules, and enzymatic catalysis. Here we examine the effect of surface fluorination on water-protein interactions. Modification of designed coiled-coil proteins by incorporation of 5,5,5-trifluoroleucine or (4S)-2-amino-4-methylhexanoic acid enables systematic examination of the effects of side-chain volume and fluorination on solvation dynamics. Using ultrafast fluorescence spectroscopy, we find that fluorinated side chains exert electrostatic drag on neighboring water molecules, slowing water motion at the protein surface

Variability in coastal zone color scanner (CZCS) Chlorophyll imagery of ocean margin waters off the US East Coast.

Abstract The purpose of our study was to use the 7.5-year coastal zone color scanner (CZCS) image time series (Oct. 1978 to July, 1986 to study general patterns in near-surface phytoplankton chlorophyll concentrations in ocean margin waters off the US East Coast. We defined 21 relatively large study areas (>100 km 2 ) within the MAB and SAB to set boundaries for averaging and subsequent analyses. Our objective was to partition the observed CZCS-derived chlorophyll concentration (CSAT, mg m À3 ) variability of these 21 study areas within three general categories based on time scale: daily (i.e. day-week), seasonal and interannual. An additional objective was to determine relations between the temporal patterns in the 21 study areas. All available CZCS imagery (more than 3500 scenes of Level 1 imagery, i.e. top-ofthe-atmosphere radiance in satellite swath coordinates) covering some or all of our area of interest (northwest Atlantic off the US East Coast) were obtained at full resolution, processed to Level 2 (waterleaving radiance, chlorophyll concentration and other derived products in satellite swath coordinates) and mapped to two different study regions located off the southeast and northeast coasts of the US. Satellitederived estimates of near-surface chlorophyll concentrations (CSAT) were extracted on a pixel-by-pixel basis from each of the 21 study areas (chosen based on oceanographic criteria) from each of the daily composite CSAT images. For each image and when satellite coverage permitted, CSAT values were averaged to yield a time series of daily mean values for each of the 21 study areas. We used three basic approaches to quantify temporal and spatial patterns in the 21 time series: (1) multiple linear correlation, (2) structure functions (semi-variance calculations) and (3) empirical orthogonal functions (EOF). Our results show: (1) a simple annual CSAT cycle common to all ocean margin waters along the entire US East Coast, consisting of a broad peak in CSAT concentration during winter and minimum concentrations during the summer