226 research outputs found

    Electron-beam propagation in a two-dimensional electron gas

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    A quantum mechanical model based on a Green's function approach has been used to calculate the transmission probability of electrons traversing a two-dimensional electron gas injected and detected via mode-selective quantum point contacts. Two-dimensional scattering potentials, back-scattering, and temperature effects were included in order to compare the calculated results with experimentally observed interference patterns. The results yield detailed information about the distribution, size, and the energetic height of the scattering potentials.Comment: 7 pages, 6 figure

    Coulomb implosion mechanism of negative ion acceleration in laser plasmas

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    Coulomb implosion mechanism of the negatively charged ion acceleration in laser plasmas is proposed. When a cluster target is irradiated by an intense laser pulse and the Coulomb explosion of positively charged ions occurs, the negative ions are accelerated inward. The maximum energy of negative ions is several times lower than that of positive ions. The theoretical description and Particle-in-Cell simulation of the Coulomb implosion mechanism and the evidence of the negative ion acceleration in the experiments on the high intensity laser pulse interaction with the cluster targets are presented.Comment: 4 page

    Universality of Performance Indicators based on Citation and Reference Counts

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    We find evidence for the universality of two relative bibliometric indicators of the quality of individual scientific publications taken from different data sets. One of these is a new index that considers both citation and reference counts. We demonstrate this universality for relatively well cited publications from a single institute, grouped by year of publication and by faculty or by department. We show similar behaviour in publications submitted to the arXiv e-print archive, grouped by year of submission and by sub-archive. We also find that for reasonably well cited papers this distribution is well fitted by a lognormal with a variance of around 1.3 which is consistent with the results of Radicchi, Fortunato, and Castellano (2008). Our work demonstrates that comparisons can be made between publications from different disciplines and publication dates, regardless of their citation count and without expensive access to the whole world-wide citation graph. Further, it shows that averages of the logarithm of such relative bibliometric indices deal with the issue of long tails and avoid the need for statistics based on lengthy ranking procedures.Comment: 15 pages, 14 figures, 11 pages of supplementary material. Submitted to Scientometric

    High-Flux Femtosecond X-Ray Emission from Controlled Generation of Annular Electron Beams in a Laser Wakefield Accelerator

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    Annular quasimonoenergetic electron beams with a mean energy in the range 200-400 MeV and charge on the order of several picocoulombs were generated in a laser wakefield accelerator and subsequently accelerated using a plasma afterburner in a two-stage gas cell. Generation of these beams is associated with injection occurring on the density down ramp between the stages. This well-localized injection produces a bunch of electrons performing coherent betatron oscillations in the wakefield, resulting in a significant increase in the x-ray yield. Annular electron distributions are detected in 40% of shots under optimal conditions. Simultaneous control of the pulse duration and frequency chirp enables optimization of both the energy and the energy spread of the annular beam and boosts the radiant energy per unit charge by almost an order of magnitude. These well-defined annular distributions of electrons are a promising source of high-brightness laser plasma-based x rays

    Synchrotron x-ray radiation from laser wakefield accelerated electron beams in a plasma channel

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    Synchrotron x-ray radiation from laser wakefield accelerated electron beams was characterized at the HERCULES facility of the University of Michigan. A mono-energetic electron beam with energy up to 400 MeV was observed in the interaction of an ultra-short laser pulse with a super-sonic gas jet target. The experiments were performed at a peak intensity of 5×1019 W/cm2 by using an adaptive optic. The accelerated electron beam undergoes a so called "betatron" oscillation in an ion channel, where plasma electrons have been expelled by the laser ponderomotive force, and, therefore, emits synchrotron radiation. We observe broad synchrotron x-ray radiation extending up to 30 keV. We find that this radiation is emitted in a beam with a divergence angle as small as 12×4 mrad2 and can have a source size smaller than 3 microns and a peak brightness of 1022 photons/mm2/mrad2/second/0.1% bandwidth, which is comparable to currently existing 3rd generation conventional light sources. This opens up the possibility of using laser-produced "betatron" sources for many applications that currently require conventional synchrotron sources.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/85402/1/jpconf10_244_042026.pd

    Properties of electrons scattered on a strong plane electromagnetic wave with a linear polarization: classical treatment

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    The relations among the components of the exit momenta of ultrarelativistic electrons scattered on a strong electromagnetic wave of a low (optical) frequency and linear polarization are established using the exact solutions to the equations of motion with radiation reaction included (the Landau-Lifshitz equation). It is found that the momentum components of the electrons traversed the electromagnetic wave depend weakly on the initial values of the momenta. These electrons are mostly scattered at the small angles to the direction of propagation of the electromagnetic wave. The maximum Lorentz factor of the electrons crossed the electromagnetic wave is proportional to the work done by the electromagnetic field and is independent of the initial momenta. The momentum component parallel to the electric field strength vector of the electromagnetic wave is determined only by the diameter of the laser beam measured in the units of the classical electron radius. As for the reflected electrons, they for the most part lose the energy, but remain relativistic. There is a reflection law for these electrons that relates the incident and the reflection angles and is independent of any parameters.Comment: 12 pp, 3 fig

    FKF1 conveys timing information for CONSTANS stabilization in photoperiodic flowering

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    Plants use day-length information to coordinate flowering time with the appropriate season to maximize reproduction. In Arabidopsis, the long-day specific expression of CONSTANS (CO) protein is crucial for flowering induction. Although light signaling regulates CO protein stability, the mechanism by which CO is stabilized in the long-day afternoon has remained elusive. Here we demonstrate that FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1) protein stabilizes CO protein in the afternoon in long days. FKF1 interacts with CO through its LOV domain, and blue light enhances this interaction. In addition, FKF1 simultaneously removes CYCLING DOF FACTOR 1 (CDF1) that represses CO and FLOWERING LOCUS T (FT) transcription. Together with CO transcriptional regulation, FKF1 protein controls robust FT mRNA induction through multiple feedforward mechanisms that accurately control flowering timing

    Emergency response for evaluating SARS-CoV-2 immune status, seroprevalence and convalescent plasma in Argentina

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    We report the emergency development and application of a robust serologic test to evaluate acute and convalescent antibody responses to SARS-CoV-2 in Argentina. The assays, COVIDAR IgG and IgM, which were produced and provided for free to health authorities, private and public health institutions and nursing homes, use a combination of a trimer stabilized spike protein and the receptor binding domain (RBD) in a single enzyme-linked immunosorbent assay (ELISA) plate. Over half million tests have already been distributed to detect and quantify antibodies for multiple purposes, including assessment of immune responses in hospitalized patients and large seroprevalence studies in neighborhoods, slums and health care workers, which resulted in a powerful tool for asymptomatic detection and policy making in the country. Analysis of antibody levels and longitudinal studies of symptomatic and asymptomatic SARS-CoV-2 infections in over one thousand patient samples provided insightful information about IgM and IgG seroconversion time and kinetics, and IgM waning profiles. At least 35% of patients showed seroconversion within 7 days, and 95% within 45 days of symptoms onset, with simultaneous or close sequential IgM and IgG detection. Longitudinal studies of asymptomatic cases showed a wide range of antibody responses with median levels below those observed in symptomatic patients. Regarding convalescent plasma applications, a protocol was standardized for the assessment of end point IgG antibody titers with COVIDAR with more than 500 plasma donors. The protocol showed a positive correlation with neutralizing antibody titers, and was used for clinical trials and therapies across the country. Using this protocol, about 80% of convalescent donor plasmas were potentially suitable for therapies. Here, we demonstrate the importance of providing a robust and specific serologic assay for generating new information about antibody kinetics in infected individuals and mitigation policies to cope with pandemic needs.Fil: Ojeda, Diego Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: González López Ledesma, María Mora. Fundación Instituto Leloir; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pallarés, Horacio Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Costa Navarro, Guadalupe Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Instituto Leloir; ArgentinaFil: Sanchez, Lautaro Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Perazzi, Beatriz Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Villordo, Sergio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Alvarez, Diego Ezequiel. Universidad Nacional de San Martín; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Echavarría, Marcela Silvia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Oguntuyo, Kasopefoluwa Y.. Icahn School of Medicine at Mount Sinai; Estados UnidosFil: Stevens, Christian S.. Icahn School of Medicine at Mount Sinai; Estados UnidosFil: Lee, Benhur. Icahn School of Medicine at Mount Sinai; Estados UnidosFil: Carradori, Jorge. Laboratorio Lemos S.R.L; ArgentinaFil: Caramelo, Julio Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Yanovsky, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Gamarnik, Andrea Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentin

    Flowering Time Diversification and Dispersal in Central Eurasian Wild Wheat Aegilops tauschii Coss.: Genealogical and Ecological Framework

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    Timing of flowering is a reproductive trait that has significant impact on fitness in plants. In contrast to recent advances in understanding the molecular basis of floral transition, few empirical studies have addressed questions concerning population processes of flowering time diversification within species. We analyzed chloroplast DNA genealogical structure of flowering time variation in central Eurasian wild wheat Aegilops tauschii Coss. using 200 accessions that represent the entire species range. Flowering time measured as days from germination to flowering varied from 144.0 to 190.0 days (average 161.3 days) among accessions in a common garden/greenhouse experiment. Subsequent genealogical and statistical analyses showed that (1) there exist significant longitudinal and latitudinal clines in flowering time at the species level, (2) the early-flowering phenotype evolved in two intraspecific lineages, (3) in Asia, winter temperature was an environmental factor that affected the longitudinal clinal pattern of flowering time variation, and (4) in Transcaucasus-Middle East, some latitudinal factors affected the geographic pattern of flowering time variation. On the basis of palaeoclimatic, biogeographic, and genetic evidence, the northern part of current species' range [which was within the temperate desert vegetation (TDV) zone at the Last Glacial Maximum] is hypothesized to have harbored species refugia. Postglacial southward dispersal from the TDV zone seems to have been driven by lineages that evolved short-flowering-time phenotypes through different genetic mechanisms in Transcaucasus-Middle East and Asia
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