Concurrent Hypofractionated Radiotherapy and 5-Fluorouracil for Advanced Sarcomas of the Bone

Purpose. 5-Fluorouracil (5-FU) has shown radiosensitizing properties in vitro. This paper reports the effects of radiotherapy and concomitant intravenous 5-FU radiosensitization in the treatment of advanced bone sarcomas

Planar Disjoint-Paths Completion

We introduce Planar Disjoint Paths Completion, a completion counterpart of the Disjoint Paths problem, and study its parameterized complexity. The problem can be stated as follows: given a, not necessarily connected, plane graph G, k pairs of terminals, and a face F of G, find a minimum-size set of edges, if one exists, to be added inside F so that the embedding remains planar and the pairs become connected by k disjoint paths in the augmented network. Our results are twofold: first, we give an upper bound on the number of necessary additional edges when a solution exists. This bound is a function of k, independent of the size of G. Second, we show that the problem is fixed-parameter tractable, in particular, it can be solved in time f(k) · n2

An authoring tool for educators to make virtual labs

This paper focuses on the design and implementation of a tool that allows educators to author 3D virtual labs. The methodology followed is based on web 3D frameworks such as three.js and WordPress that allowed us to develop simplified interfaces for modifying Unity3D templates. Two types of templates namely one for Chemistry and one for Wind Energy labs were developed that allow to test the generalization, user-friendliness and usefulness of such an approach. Results have shown that educators are much interested on the general concept, but several improvements should be made towards the user-friendliness and the intuitiveness of the interfaces in order to allow the inexperienced educators in 3D gaming to make such an attempt.peer-reviewe