1,794 research outputs found
Experimental joint signal-idler quasi-distributions and photon-number statistics for mesoscopic twin beams
Joint signal-idler photoelectron distributions of twin beams containing
several tens of photons per mode have been measured recently. Exploiting a
microscopic quantum theory for joint quasi-distributions in parametric
down-conversion developed earlier we characterize properties of twin beams in
terms of quasi-distributions using experimental data. Negative values as well
as oscillating behaviour in quantum region are characteristic for the
subsequently determined joint signal-idler quasi-distributions of integrated
intensities. Also the conditional and difference photon-number distributions
are shown to be sub-Poissonian and sub-shot-noise, respectively.Comment: 7 pages, 6 figure
Matrix formulation of superspace on 1D lattice with two supercharges
Following the approach developed by some of the authors in recent papers and
using a matrix representation for the superfields, we formulate an exact
supersymmetric theory with two supercharges on a one dimensional lattice. In
the superfield formalism supersymmetry transformations are uniquely defined and
do not suffer of the ambiguities recently pointed out by some authors. The
action can be written in a unique way and it is invariant under all
supercharges. A modified Leibniz rule applies when supercharges act on a
superfield product and the corresponding Ward identities take a modified form
but hold exactly at least at the tree level, while their validity in presence
of radiative corrections is still an open problem and is not considered here.Comment: 25 page
Modified-Source Gravity and Cosmological Structure Formation
One way to account for the acceleration of the universe is to modify general
relativity, rather than introducing dark energy. Typically, such modifications
introduce new degrees of freedom. It is interesting to consider models with no
new degrees of freedom, but with a modified dependence on the conventional
energy-momentum tensor; the Palatini formulation of theories is one
example. Such theories offer an interesting testing ground for investigations
of cosmological modified gravity. In this paper we study the evolution of
structure in these ``modified-source gravity'' theories. In the linear regime,
density perturbations exhibit scale dependent runaway growth at late times and,
in particular, a mode of a given wavenumber goes nonlinear at a higher redshift
than in the standard CDM model. We discuss the implications of this
behavior and why there are reasons to expect that the growth will be cut off in
the nonlinear regime. Assuming that this holds in a full nonlinear analysis, we
briefly describe how upcoming measurements may probe the differences between
the modified theory and the standard CDM model.Comment: 22 pages, 6 figures, uses iopart styl
Testing Reactive Probabilistic Processes
We define a testing equivalence in the spirit of De Nicola and Hennessy for
reactive probabilistic processes, i.e. for processes where the internal
nondeterminism is due to random behaviour. We characterize the testing
equivalence in terms of ready-traces. From the characterization it follows that
the equivalence is insensitive to the exact moment in time in which an internal
probabilistic choice occurs, which is inherent from the original testing
equivalence of De Nicola and Hennessy. We also show decidability of the testing
equivalence for finite systems for which the complete model may not be known
Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation
The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV) and development of progressive multifocal leukoencephalopathy (PML). To correlate natalizumab-induced phenotypic modifications of peripheral blood T-lymphocytes with JCV reactivation, JCV-specific antibodies (serum), JCV-DNA (blood and urine), CD49d expression and relative abundance of peripheral blood T-lymphocyte subsets were longitudinally assessed in 26 natalizumab-treated RRMS patients. Statistical analyses were performed using GraphPad Prism and R. Natalizumab treatment reduced CD49d expression on memory and effector subsets of peripheral blood T-lymphocytes. Moreover, accumulation of peripheral blood CD8+ memory and effector cells was observed after 12 and 24 months of treatment. CD4+ and CD8+ T-lymphocyte immune-activation was increased after 24 months of treatment. Higher percentages of CD8+ effectors were observed in subjects with detectable JCV-DNA. Natalizumab reduces CD49d expression on CD8+ T-lymphocyte memory and effector subsets, limiting their migration to the central nervous system and determining their accumulation in peripheral blood. Impairment of central nervous system immune surveillance and reactivation of latent JCV, can explain the increased risk of PML development in natalizumab-treated RRMS subjects
The Deconfinement Phase Transition in One-Flavour QCD
We present a study of the deconfinement phase transition of one-flavour QCD,
using the multiboson algorithm. The mass of the Wilson fermions relevant for
this study is moderately large and the non-hermitian multiboson method is a
superior simulation algorithm. Finite size scaling is studied on lattices of
size , and . The behaviours of the
peak of the Polyakov loop susceptibility, the deconfinement ratio and the
distribution of the norm of the Polyakov loop are all characteristic of a
first-order phase transition for heavy quarks. As the quark mass decreases, the
first-order transition gets weaker and turns into a crossover. To investigate
finite size scaling on larger spatial lattices we use an effective action in
the same universality class as QCD. This effective action is constructed by
replacing the fermionic determinant with the Polyakov loop identified as the
most relevant Z(3) symmetry breaking term. Higher-order effects are
incorporated in an effective Z(3)-breaking field, , which couples to the
Polyakov loop. Finite size scaling determines the value of where the first
order transition ends. Our analysis at the end - point, , indicates
that the effective model and thus QCD is consistent with the universality class
of the three dimensional Ising model.
Matching the field strength at the end point, , to the
values used in the dynamical quark simulations we estimate the end point,
, of the first-order phase transition. We find which corresponds to a quark mass of about 1.4 GeV .Comment: LaTex, 25 pages, 18 figure
Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages
This study provides the proof of principle that probing the host and the microbe transcriptomes simultaneously is a valuable means to accessing unique information on host pathogen interactions. Our results also underline the extraordinary plasticity of host cell and pathogen responses to infection, and provide a solid framework to further understand the complex mechanisms involved in immunity to M. tuberculosis and in mycobacterial adaptation to different intracellular environments
Predictions and recent results in susy on the lattice
In this brief review, I summarize the current theoretical knowledge in
supersymmetry on the lattice, with special emphasis on recent results in the
framework of N=1 supersymmetric Yang Mills theory, Wess-Zumino model and
Yang-Mills theory with extended supersymmetries.Comment: 15 pages. Invited brief review for Modern Physics Letters A. Minor
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