Emotion Language and Emotion Narratives of Turkish-English Late Bilinguals

The primary focus of this research was to investigate the emotion language and emotion narratives of Turkish-English late bilinguals who have been living in the U.S. Previous research has shown that the emotion language and narratives of second language learners and native speakers of English are different. This study focused on late bilinguals who had learnt English in instructed settings in their home country, and came to the U.S. for M.A. and Ph.D. degrees. The study consisted of two parts. In the first part, the elicited personal narratives of Turkish-English late bilinguals in English were compared to those elicited from native speakers of English with regard to both emotion and emotion-laden word production and narrative structure. The results showed that there were differences between the emotion language and narratives of the bilinguals and native speakers in their English narratives. In the second part of the study, personal narratives were elicited from Turkish-English late bilinguals in their first language, Turkish and their emotion language and narrative structure from their English narratives were compared to their narratives produced in Turkish. Similarly, the results showed that the emotion language and emotion narratives of bilinguals in English and Turkish were different. In conclusion, late bilinguals\u27 emotion language and narratives are different in their first and second languages. Furthermore, they are different from the emotion language and narratives of native speakers

İmalat Sektöründe Faaliyet Gösteren KOBİ’lerde İnsan Kaynakları Yönetimi Uygulamalarının Belirleyicileri: Eskişehir Örneği

İnsan kaynakları yönetimi (İKY) uygulamaları işletmelerin en önemli ve ikame edilmesi çok güç olan kaynaklarından olan çalışanlar ile işletme yönetimi arasındaki ilişkileri kapsayan akademik çalışma ve uygulama alanıdır. İnsan kaynakları uygulamaları bir işletmede insan kaynağının daha verimli ve daha etkili bir şekilde nasıl çalıştırılacağının anahtarıdır. Bu çalışmada, imalat sektöründe faaliyet gösteren KOBİ’lerdeki İKY uygulamaları Eskişehir örneği üzerinden incelenmiştir. Araştırmanın amacı doğrultusunda, Eskişehir ilinde imalat sektöründe faaliyet gösteren 50 ile 250 arası çalışan sayısına sahip küçük ve orta ölçekli işletmeler incelenmiştir. TOBB verilerine göre, 2017 yılında Eskişehir’de imalat sektöründe, 50 ila 250 kişi çalıştıran imalatçı işletme sayısı 146’dır. Bu işletmeler arasından maksimum çeşitlilik örneklemesi yöntemiyle seçilen 19 işletmede örnek olay yöntemiyle araştırma gerçekleştirilmiştir. Yapılandırılmış ve yarı-yapılandırılmış sorulardan oluşan bir görüşme formuyla KOBİ’lerin varsa insan kaynakları yöneticileri/uzmanları ve tepe yöneticileri ile görüşmeler yapılmıştır. Araştırma sonuçlarına göre işletmelerin büyüklüğü ve yaşının, müşterilerin gücünün ve resmi düzenlemelerin İKY uygulamalarının benimsenmesinde etkili olduğu bulunmuştur

İmalat Sektöründe Faaliyet Gösteren KOBİ’lerde İnsan Kaynakları Yönetimi Uygulamalarının Belirleyicileri: Eskişehir Örneği

İnsan kaynakları yönetimi (İKY) uygulamaları işletmelerin en önemli ve ikame edilmesi çok güç olan kaynaklarından olan çalışanlar ile işletme yönetimi arasındaki ilişkileri kapsayan akademik çalışma ve uygulama alanıdır. İnsan kaynakları uygulamaları bir işletmede insan kaynağının daha verimli ve daha etkili bir şekilde nasıl çalıştırılacağının anahtarıdır. Bu çalışmada, imalat sektöründe faaliyet gösteren KOBİ’lerdeki İKY uygulamaları Eskişehir örneği üzerinden incelenmiştir. Araştırmanın amacı doğrultusunda, Eskişehir ilinde imalat sektöründe faaliyet gösteren 50 ile 250 arası çalışan sayısına sahip küçük ve orta ölçekli işletmeler incelenmiştir. TOBB verilerine göre, 2017 yılında Eskişehir’de imalat sektöründe, 50 ila 250 kişi çalıştıran imalatçı işletme sayısı 146’dır. Bu işletmeler arasından maksimum çeşitlilik örneklemesi yöntemiyle seçilen 19 işletmede örnek olay yöntemiyle araştırma gerçekleştirilmiştir. Yapılandırılmış ve yarı-yapılandırılmış sorulardan oluşan bir görüşme formuyla KOBİ’lerin varsa insan kaynakları yöneticileri/uzmanları ve tepe yöneticileri ile görüşmeler yapılmıştır. Araştırma sonuçlarına göre işletmelerin büyüklüğü ve yaşının, müşterilerin gücünün ve resmi düzenlemelerin İKY uygulamalarının benimsenmesinde etkili olduğu bulunmuştur

Adsorption challenge in the PDMS-based microfluidic systems for drug screening application

Drug screening is one of the demand areas due to close and direct dependency on human health. On the other hand, recently microfluidic systems have been increasingly used for drug development and screening purposes. However, this system has some challenges such as adsorption issue which can effect pharmacokinetic-pharmacodynamic (PK-PD) of the drugs. Thus, in this research, the issue was characterized and evaluated by UV-Vis spectrophotometry and FTIR spectroscopy devices as a model drug of cisplatin. Despite of strong relationship between logP and adsorption, and the very low value of logP in the drug candidate, the results for both apical and basal planes of the microfluidic chip confirmed the adsorption. In the UV-Vis spectrophotometry, the basal plane show 5%, and 10% higher adsorption compared to apical and control polydimethylsiloxane (PDMS)-based microfluidic. Additionally, the FTIR patterns were a good coincide with UV-Vis results

Recent Advances in Health Biotechnology During Pandemic

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in 2019, cut the epoch that will make profound fluctuates in the history of the world in social, economic, and scientific fields. Urgent needs in public health have brought with them innovative approaches, including diagnosis, prevention, and treatment. To exceed the coronavirus disease 2019 (COVID-19) pandemic, various scientific authorities in the world have procreated advances in real time polymerase chain reaction (RT-PCR) based diagnostic tests, rapid diagnostic kits, the development of vaccines for immunization, and the purposing pharmaceuticals for treatment. Diagnosis, treatment, and immunization approaches put for- ward by scientific communities are cross-fed from the accrued knowledge of multidisciplinary sciences in health biotechnology. So much so that the pandemic, urgently prioritized in the world, is not only viral infections but also has been the pulsion in the development of novel approaches in many fields such as diagnosis, treatment, translational medicine, virology, mi- crobiology, immunology, functional nano- and bio-materials, bioinformatics, molecular biol- ogy, genetics, tissue engineering, biomedical devices, and artificial intelligence technologies. In this review, the effects of the COVID-19 pandemic on the development of various scientific areas of health biotechnology are discussed

A case with mutation in the TNFRSF1A gene

Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is a rare autosomal dominant hereditary diseaseof the group of recurrent autoinflammatory syndromes. Theprognosis is generally good; the main risk is the developmentof amyloidosis. Corticosteroid therapy is usually administeredduring attacks. Severe cases require treatment with biologicalagents. In this study, DNA fragment analysis and next generation sequencing methods were applied to elucidate the patientwith recurrent fever and joint pain. A six-year-old girl with recurrent fever and joint pain was referred to a medical geneticsclinic for a etiologic study on the consideration of autoinflammatory disease. On physical examination, there was no featureexcept bilateral swelling in the knee. Echocardiography andknee magnetic resonance examination were unremarkable. Thesuperficial tissue ultrasonographic examination of the bilateralknee region was observed fluid accumulation 30 mm on the leftand 15mm on the right in the thickest site, at the suprapatellarlevel. Fluid was observed in the joint range. In the sample fromthe joint fluid, the white blood cell was 74000/m³. In the analysisof the peripheral blood, white blood cell count was 17.7x10³/µL,CRP: 31 mg/L, fibrinogen: 4.6g/L, sedimentation: 25 mm/h. The24-hour urine protein/creatinine was 0.27 mg/mg. FMF fragment analysis revealed no mutation and the diagnosis of FMFwas excluded. The next generation sequence analysis revealed alikely pathogenic, heterozygous c.362G&gt;A(R121Q; rs4149584) alteration of the TNFRSF1A gene (ENST00000162749). Then thesegregation analysis was planned. In this study, we pointed outthe TNFRSF1A mutation in periodic fever syndrome cases. Earlydiagnosis by genetic testing can prevent amyloidosis.</p

Anormal uterin kanama ile başvuran ve endometriyal polip saptanan hastalarda uterin arter Doppler sonografi, salin hidrosonografi ve patoloji sonuçlarinin karşilaştirilmasi

Objective: The aim of this study was to compare uterine artery doppler sonography, saline infusion sonography and endometrial biopsy results in premenopausal patients with abnormal uterine bleeding. Material and Methods: This study was performed on 60 premenopausal patients who had abnormal uterine bleeding and whose endometrial thickness were ? 5 mm. Transvaginal ultrasonography, uterine artery Doppler sonography and saline hydrosonography were performed for each patient. Afterwards, endometrial biopsies were performed and sent to the pathology department. After the pathology results were delivered, 25 patients were included in the endometrial polyp group. Patients with abnormal uterine bleeding, who didn't have any intracavitary lesions were considered as the control group. The result for transvaginal ultrasonography, uterine artery doppler sonography and saline hydrosonography were compared with pathology results. Results: The mean uterine artery resistance index value in the endometrial polyp group was 0.63 ± 0.2 and in the control group it was 0.66 ± 0.17 (p= 0.48). The mean uterine artery pulsatility index in the endometrial polyp group was 1.75 ± 0.74 and in the control group it was 1.95 ± 0.63 (p= 0.31). The sensitivity, specificity, positive predictive value and negative predictive value of saline hydrosonography in directly visualizing endometrial polyps were 96%, 84.6%, 95.7% and 85.7%, respectively (p< 0.05). Conclusion: Uterine artery doppler sonography dose not have any additive value to conventional ultrasonography and salin hydrosonography, in differentiating endometrial polyps from patients with abnormal uterine bleeding who do not have any intracavitary lesions. Copyright © 2010 by Türkiye Klinikleri