Self-sorting in two-dimensional assemblies of simple chiral molecules

Structural modification of adsorbed overlayers by means of external factors is an important objective in the fabrication of stimuli-responsive materials with adjustable physicochemical properties. In this contribution we present a coarse-grained Monte Carlo model of the confinement-induced chiral self-sorting of hockey stick-shaped enantiomers adsorbed on a triangular lattice. It is assumed that the adsorbed overlayer consists of "normal" molecules that are capable of adopting any of the six planar orientations imposed by the symmetry of the lattice and molecular directors having only one permanent orientation, that reflect the coupling of these species with an external directional field. Our investigations focus on the influence of the amount fraction of the molecular directors, temperature and surface coverage on the extent of the chiral segregation. The simulated results demonstrate that the molecular directors can have a significant effect on the ordering in enantiopure overlayers, while for the corresponding racemates their role is largely diminished. These findings can be helpful in designing strategies to improve methods of fabrication of homochiral surfaces and enantioselective adsorbents.Comment: 10 pages, 8 figure

High dispersion observations of Venus during 1972. The CO2 band at 7820 angstrom

Photographic plates of Venus which show the spectrum of the carbon dioxide band at 7820A were obtained at Table Mountain Observatory in September-October 1972. These spectra showed a semi-regular 4-day variation in the CO2 abundance over the disk of the planet. Evidence for temporal variations in the rotational temperature of this band and temperature variations over the disk was found. The two quantities, CO2 abundance and temperature, do not show any obvious relationship; however, an increase in the temperature usually is accompanied by a decrease in the abundance of CO2. The average temperature, found from a curve of growth analysis assuming a constant CO2 line of width, is 249 plus or minus 1.4 K (one standard deviation)

High-dispersion spectroscopic observations of Venus during 1968 and 1969 II. The carbon-dioxide band at 8689A

Thirty well-exposed photographic plates showing the spectrum of the carbon dioxide band at 8689A in the atmosphere of Venus were obtained during 1968 and 1969. All spectra were obtained at a dispersion of 2 A/mm for Venus phase angles varying from 10 deg. to 126 deg. Rotational temperatures ranging from 236 K to 274 K were found. The average value of the rotational temperature is 246 + or - 1 K (one standard deviation); for 1967 observations, the rotational temperatures ranged from 222 to 248 K, with an average value of 238 + or - 4 K. The variation of the equivalent width of the 8689A band, with Venus phase angle, was very similar for the two sets of observations (53 plates). The temporal variations, of approximately 30 percent, were comparable with the phase variations over this limited range of phase angle

Open, sesame! Introducing access control to voice services

Personal voice assistants (VAs) are shown to be vulnerable against record–and–replay, and other acoustic attacks which allow an adversary to gain unauthorized control of connected devices within a smart home. Existing defenses either lack detection and management capabilities or are too coarse-grained to enable flexible policies on par with other computing interfaces. In this work, we present Sesame, a lightweight framework for edge devices which is the first to enable fine-grained access control of smart-home voice commands. Sesame combines three components: Automatic SpeechRecognition, Natural Language Understanding (NLU) and a Policymodule. We implemented Sesame on Android devices and demonstrate that our system can enforce security policies for both Alexa and Google Home in real-time (362ms end-to-end inference time), with a lightweight (<25MB) NLU model which exhibits minimal accuracy loss compared to its non-compact equivalent

From C/Mrkos to P/Halley: 30 years of cometary spectroscopy

An Atlas of Cometary Spectra was compiled, as a sequel to the well-known Atlas published by Swings and Haser in 1956. The new atlas comprises some 400 reproductions of cometary spectra secured in the world's largest observatories during the three decades or so from the passage of comet Mrkos 1957 V, for which the very first high-dispersion spectrum was obtained, to the return of Halley's comet. The illustrations refer to 40 different comet apparitions; they are grouped into a set of 186 loose 11 x 14 in. plates, while the texts, comments, and relevant data are given in a separate booklet. The main purpose of this atlas is to show in detail the tremendous progress which was achieved in cometary spectroscopy during the period covered, essentially thanks to the use of high-resolution coude spectrographs and large telescopes, the considerable extension of the observed wavelength range, and the advent of electronic detectors. It is divided into two parts. Part 1, which contains about two-thirds of the selected material, presents photographic spectra, while electronically recorded spectra covering the vacuum ultraviolet, through the optical, infrared, and radio regions appear in Part 2

A Tight Upper Limit on Oscillations in the Ap star Epsilon Ursae Majoris from WIRE Photometry

Observations of Epsilon UMa obtained with the star tracker on the Wide Field Infrared Explorer (WIRE) satellite during a month in mid-2000 are analyzed. This is one of the most precise photometry of an Ap star. The amplitude spectrum is used to set an upper limit of 75 parts per million for the amplitude of stellar pulsations in this star unless it accidentally oscillates with a single mode at the satellite orbit, its harmonics or their one day aliases. This is the tightest limit put on the amplitude of oscillations in an Ap star. As the rotation period of Epsilon UMa is relatively short (5.1 d), it cannot be argued that the observations were made at a wrong rotational phase. Our results thus support the idea that some Ap stars do not pulsate at all.Comment: 4 pages, 4 figures, 2 style files, accepted for publication in ApJ

The Śnieżka peatland as a candidate for the Global Boundary Stratotype Section and Point for the Anthropocene series

The subalpine, atmospherically fed Śnieżka peatland, located in the Polish part of the Sudetes, is one of the nominated candidates for the GSSP of the Anthropocene. Data from two profiles, Sn1 (2012) and Sn0 (2020), from this site are critical for distinguishing the proposed epoch, while an additional core Sn2 is presented to support main evidence. The Sn0 archive contains a wide array of critical markers such as plutonium (Pu), radiocarbon (F14C), fly ash particles, Hg and stable C and N isotopes which are consistent with the previously well documented 210Pb/14C dated Sn1 profile, which provides a high-resolution and comprehensive database of trace elements and rare earth elements (REE), Pb isotopes, Pu, Cs, pollen and testate amoebae. The 1952 worldwide appearance of Pu, owing to its global synchronicity and repeatability between the cores, is proposed here as a primary marker of the Anthropocene, supported by the prominent upturn of selected chemostratigraphic and biostratigraphic indicators as well as the appearance of technofossils and artificial radionuclides

Thalidomide, dexamethasone and lovastatin with autologous stem cell transplantation as a salvage immunomodulatory therapy in patients with relapsed and refractory multiple myeloma

The treatment of patients with multiple myeloma usually includes many drugs including thalidomide, lenalidomide and bortezomib. Lovastatin and other inhibitors of HMG-CoA reductase demonstrated to exhibit antineoplasmatic and proapoptotic properties in numerous in vitro studies involving myeloma cell lines. We treated 91 patients with relapsed or refractory multiple myeloma with thalidomide, dexamethasone and lovastatin (TDL group, 49 patients) or thalidomide and dexamethasone (TD group, 42 patients). A clinical response defined of at least 50% reduction of monoclonal band has been observed in 32% of TD patients and 44% of TDL patients. Prolongation of overall survival and progression-free survival in the TDL group as compared with the TD group has been documented. The TDL regimen was safe and well tolerated. The incidence of side effects was comparable in both groups. Plasma cells have been cultured in vitro with thalidomide and lovastatin to assess the impact of both drugs on the apoptosis rate of plasma cells. In vitro experiments revealed that the combination of thalidomide and lovastatin induced higher apoptosis rate than apoptosis induced by each drug alone. Our results suggest that the addition of lovastatin to the TD regimen may improve the response rate in patients with relapsed or refractory myeloma

Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk

Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia ris