133 research outputs found
Deflection compensation on a force sensing mobile machine tool
Within this paper, a model based deflection compensation for a mobile machine tool prototype is presented. The model compensates the deflection of the tool center point (TCP) based on strain gauge measurements at the machines foot modules. The measured strains at each foot are used to calculate pose dependent gravitational forces as well as disturbance forces. These forces are then passed to the model. Hence, the model reconstructs the deflection of the TCP based on the measured forces at the foot modules
Thermally Induced Clamping Force Deviations in a Sensory Chuck for Thin-Walled Workpieces
Deviations between nominal and actual tolerances are a challenging problem during turning processes of thin-walled workpieces. One main cause of these deviations is the clamping force applied by the turning chuck to hold the workpiece. Due to the low stiffness of thin-walled workpieces, large workpiece deformations can occur even when clamping forces are low. For this reason, the clamping force needs to be precisely adjusted. A possible approach are chucks with integrated actuators. As a result of the more direct power transmission, these chucks have a potentially higher clamping force accuracy compared to conventional external actuation. However, integrated actuators are additional heart sources resulting in thermal loads and thermally induced deformations of the chuck components. Due to the resulting mechanical distortion of the chuck system, the precise adjustment of clamping forces is not possible. Thus, this paper evaluates the thermally induced clamping force deviations on a novel turning chuck with four integrated electric drives. A test bench is used to analyse both a single drive and the combination of all four drives regarding the temperature effect on the clamping force adjustability. A clamping force deviation of up to 26% is observed. Based on the measured chuck temperature, a compensation method is introduced leading to a clamping force accuracy of 96.9%
Обоснование технологии гидравлического разрыва пласта на примере Приобского нефтяного месторождения (ХМАО)
В данной работе представленны обоснования технологии гидравлического разрыва пласта в низкопродуктивных пластах Приобского месторождения. В результате было предложено проведение многостадийного ГРП с увеличением стадий до 8 и на основе углеводородного геля.This paper presents the substantiation of the technology of hydraulic fracturing in low-productive formations of the Priobskoye field. As a result, it was proposed to conduct a multi-stage hydraulic fracturing with an increase in stages up to 8 and based on a hydrocarbon gel
Forum: Feminism in German Studies
From Professor Wallach\u27s contribution entitled Jews and Gender :
To consider Jews and gender within German Studies is to explore the evolution of German‐Jewish Studies with respect to feminist and gender studies. At times this involves looking beyond German Studies to other scholarship in Jewish gender studies, an interdisciplinary subfield in its own right. Over the past few decades, the focus on gender within German‐Jewish Studies has experienced several shifts in line with broader trends: an initial focus on the history of Jewish women and feminist movements gradually expanded to encompass the study of gender identity, masculinity, and sexuality. Historical and literary scholarly approaches now operate alongside and in dialogue with interdisciplinary scholarship in cultural studies, film and visual studies, performance studies, and other fields. [excerpt
The paf gene product modulates asexual development in Penicillium chrysogenum
Penicillium chrysogenum secretes a low molecular weight, cationic and cysteine-rich protein (PAF). It has growth inhibitory activity against the model organism Aspergillus nidulans and numerous zoo- and phytopathogenic fungi but shows only minimal conditional antifungal activity against the producing organism itself
Structural determinants of opioid and NOP receptor activity in derivatives of buprenorphine
The unique pharmacological profile of buprenorphine has led to its considerable success as an analgesic and as a treatment agent for drug abuse. Activation of nociceptin/orphanin FQ peptide (NOP) receptors has been postulated to account for certain aspects of buprenorphine’s behavioural profile. In order to investigate the role of NOP activation further, a series of buprenorphine analogues has been synthesised with the aim of increasing affinity for the NOP receptor. Binding and functional assay data on these new compounds indicate that the area around C20 in the orvinols is key to NOP receptor activity, with several compounds displaying higher affinity than buprenorphine. One compound, 1b, was found to be a mu opioid receptor partial agonist of comparable efficacy to buprenorphine, but with higher efficacy at NOP receptors
Molecular pharmacology : design of bifunctional prourokinase derivatives and studies on the molecular mode of action of thalidomide
Immunomodulation by thalidomide : Systematic review of the literature and of unpublished observations
Conditional effects of gaze on automatic imitation: the role of autistic traits
Repository of the study: Trilla, I., Wnendt, H. & Dziobek, I. Conditional effects of gaze on automatic imitation: the role of autistic traits.
Sci Rep 10, 15512 (2020). https://doi.org/10.1038/s41598-020-72513-
Conditional effects of gaze on automatic imitation: the role of autistic traits
Establishing direct gaze has been shown to enhance the tendency to automatically imitate the other person’s actions, an effect that seems to be reduced in autism. Most previous studies, however, used experimental tasks that may have confounded the measurement of automatic imitation with spatial compatibility effects. This calls into question whether gaze cues regulate automatic imitation, or instead affect domain-general processes of response inhibition. Using a task that disentangled imitative from spatial compatibility effects, the current study re-examined the role of autistic traits on the modulation of automatic imitation by direct and averted gaze cues. While our results do not provide evidence for an overall significant influence of gaze on neither automatic imitation nor spatial compatibility, autistic traits were predictive of a reduced inhibition of imitative behaviour following averted gaze. Nonetheless, exploratory analyses suggested that the observed modulation by autistic traits may actually be better explained by the effects of concomitant social anxiety symptoms. In addition, the ethnicity of the imitated agent was identified as another potential modulator of the gaze effects on automatic imitation. Overall, our findings highlight the contextual nature of automatic imitation, but call for a reconsideration of the role of gaze on imitative behaviour
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