Electroacupuncture attenuates working memory impairement after chronic stress exposure in rat

Chronic stress (CS) exposure causes cytogenic and structural changes in the hipocampus which lead to cognitive impairment. Acupuncture has been shown to reduce cortisol secretion and protects hipocampus from stress-related damage. We hypothesize that acupunture can alleviate stress-induced working memory deficit.mthis study aimed to investigate whether electroacupuncture (EA) can improve memory in chronic stress model in rat. This was an experimental study with pretest and postest control group design. Rats were divided randomly into four groups: control group (C), CS group (T1), EA group (T2), and EA plus CS group (T3). Working memory was assessed using Eight-arm radial maze. A marked decrease in working memory was observed in the CS group demonstrated by more working memory correct errors (p=0.020) and incorrect errors (p=0.024) than control group. The CS plus EA rats made fewer working memory correct error (p=0.001) and incorrect error (p=0.000) compared to the CS only group. EA treatment in non-stressed rats did not significantly improve working memory compared to control. Chronic stress decreases working memory in rats. EA treatment at Baihui (DU 20) and Zusanli (ST 36) significantly attenuates stress induced working memory deficits in rats

PERANCANGAN APLIKASI DASHBOARD WMS BERBASIS WEB SERVICE DENGAN MENGGUNAKAN TEKNOLOGI .NET WEB SERVICE DAN PHP

Warehouse Management System needs an item inventory, configuration saving method of items, integration among warehouses, and warehouse finance control. All of the aspects must be well arranged, in order to avoid warehouses’s work performance decrease that can affect to supply chain profit. To avoid the supply chain from losses, a warehouses need a system that can help to maintain and manage all of warehouse’s variables. A system that can implemented is WMS Dashboard. WMS Dashboard is an application that can show the warehouse’s data realtime and with high accuration. WMS Dashboard’s services are made by using ASP.NET Web Service Technology which use SOAP protocol and WSDL interface so it support multi platform system to system communication which using HTTP protocol. The database of WMS Dashboard is made by using MS SQL Server DBMS which has fully compatibility with other applications that made by .NET Framework. Object oriented PHP is need to made the application for client side. WSDL of WMS dashboard application consist of 56 services. The services has been integrated with WMS Dashboard Application which based on PHP, so it would be accessed easily, and it can be used to help maintain and manage the Warehouse System variables

The Effect of Reading Activity on Verbal Fluency in Older Adults

Introduction: The high prevalence of dementia affecting verbal fluency have been one of the global major concerns. Therefore, strategies to maintain or improve the verbal fluency in older adults is needed. Neuroplasticity-based program in the form of reading has been shown to affect the verbal fluency. Objective: This study aims to evaluate the effect of reading activity on verbal fluency in the older adults.Methods: This was a quasi-experimental study with pretest-posttest control group design. Thirty older adults were included. The inclusion criteria were more than 60 years of age, being to speak, being able to read, scores > 24, for the Mini-Mental State Examination (MMSE) score, having intention to fill out the reading habits questionnaire criteria. The exclusion criteria were the history of hypertension, diabetes mellitus, and psychiatric disorders, head trauma injury of neurological disorders, hearing loss and alcohol use. The patients were assigned into three groups: the control group (C-G), the 15-minute reading intervention group (G-15), and 30-minute reading intervention group (G-30). The reading aloud activity was given for 14 days. The verbal fluency was evaluated. Statistical analysis was performed using oneway ANOVA, Post Hoc, and paired T-test.Results: There were significant differences among groups in post-test phonemic score (p0.05).Conclusion: The reading activity intervention for two weeks affects verbal fluency in older adults by increasing the phonemic score but not semantic score

DECREASED PAIN SCALE BASED ON CRITICAL PAIN OBSERVATION TOOL (CPOT) AND BEHAVIORAL PAIN SCALE NON-INTUBATED (BPS-NI) IN PATIENTS WITH REDUCED CONSCIOUSNESS BY CLASSICAL MUSIC INTERVENTION IN UNS HOSPITAL

Patient with reduced consciousness needs attention to their comfort as well as pain during treatment. Listening to classical music caused relaxation and pain reduction. This study aimed to determine the effect of classical music on the CPOT score, BPS-NI, and cortisol levels in patients with reduced consciousness. The research was conducted by using a pretest-posttest control group design. 18 patients were divided into the control group (C) and the classical music group (M). Classical music was played for 3 days respectively that consisted of 3 sessions per day. Furthermore, each patient was tested for cortisol levels on the third day. Comparative test of mean difference between pre-intervention and post-intervention obtained significant results in CPOT (p= 0.000) and BPS-NI (p= 0.001) measurements in all groups. Tukey's post-hoc test obtained significant results in which the M group had a lower mean score. The mean of cortisol level was higher in M group (14.7 μg/dL) compared to the C group (12.96 μg/dL), although not significant statistically (p= 0.67). Listening to classical music for patients with reduced consciousness decreased the pain scale. This was supported by the average of cortisol levels that were higher in the M group, considering that cortisol was a hormone that prevents pain

Pengaruh Ekstrak Etanol Pegagan (Centella asiatica ) Terhadap Volume Hippocampus Tikus (Rattus norvegicus) Pasca Stres Kronik

Background. Chronic stress caused by restraint stress induces an increase in corticosterone (glucocorticoid) that result decreased hippocampal vollume. Centella asiatica has long been used for various neurological disturbances in Southeast Asian countries. Aims. The research aims to investigate the effects of ethanol extracts of Centella Asiatica to prevent the decrease of hippocampal vollume after chronic stress. Methods. Thirty male adult rats (Sprague Dawley) with body weight of 250-350 gram was randomly subdivided into six groups of treatments: Nonstress control group was given 2% Pulvis Gummi Arabicum (PGA), Stress control groups( PGA 2 %), groups treated with fluoxetine 10mg/kgbw/day , and Ca150,  Ca300, Ca600 containing ethanol extracts of Centella asiatica with doses 150 mg/kgbw/day, 300 mg/kgbw/day, 600 mg/kgbw/day a, respectively followed by restraint stress.  After 21 days of stress, rats underwent Morris Water Maze test for 6 days, perfused, and hippocampus was collected for histological processing. Toluidine blue staining is used to asses the estimation of hippocampal volume. Results. The estimated hippocampal volume were 3.1512 ± 1.01 (nonstress), 2.4736 ± 0.10 (stress), 2.7018 ± 1.06 (Ca150), 2.7405 ± 1.19 (Ca300), 2.2678 ± 0.82  (Ca600) and 2.5818 ± 0.70 (Fluoxetine). Statistic test showed that there were no significant diferrence between stress control group and groups treated. Conclusion. There is no the significant effects of Ethanol extracts of Centella Asiatica to prevent the decrease of hippocampal vollume after chronic stress

Hubungan Postur Kerja dengan Kejadian Nyeri Leher pada Pembatik di Kampung Batik Laweyan Surakarta

Nyeri leher merupakan salah satu keluhan muskuloskeletal yang sering dikeluhkan masyarakat. Postur kerja tidak ergonomis merupakan salah satu faktor risiko yang dapat menyebabkan nyeri leher. Pada pembatik, postur kerja tidak alamiah dilakukan dalam waktu lama beserta gerakan berulang. Penelitian ini bertujuan untuk mengetahui hubungan postur kerja terhadap kejadian nyeri leher pada pembatik. Penelitian ini merupakan penelitian observasional analitik dengan desain cross sectional. Teknik sampling yang digunakan adalah total sampling. Subjek penelitian merupakan 41 pembatik yang memenuhi kriteria inklusi dan eksklusi. Postur kerja pembatik diukur dengan Rapid Upper Limb Assessment (RULA). Pengukuran nyeri leher menggunakan kuesioner Neck Disability Index (NDI). Data dianalisis menggunakan uji korelasi Kendall's tau. Hasil penelitian postur pada pembatik paling banyak berisiko tinggi yaitu pada 25 orang. Untuk nyeri leher yang paling banyak dikeluhkan pembatik berada pada kategori nyeri ringan pada 26 orang. Berdasarkan uji analisis bivariat menggunakan uji korelasi Kendall's tau, didapatkan hasil signifikan (p=0,014; r=0,358). Terdapat hubungan yang signifikan dengan tingkat korelasi yang lemah antara postur kerja dengan kejadian nyeri leher pada pembatik di Kampung Batik Laweyan Surakarta. Kata Kunci:Postur kerja, nyeri leher, dan pembatik

PENGARUH MENDENGARKAN MUROTTAL AL-QUR’AN TERHADAP MEMORI KERJA

It is important to optimize working memory because it transforms, synergizes and constantly updates new and old information. One way to optimize working memory is to listen to Murottal Al-Qur'an, because it has a harmonious tone which can stabilize the mind to properly process the information. This study aims to determine the effect of listening to the Al-Quran murottal on working memory. The research subjects were 24 students of Psikologi 2017, grouped equally in the control and experimental groups. An experimental intervention was administered for 15 consecutive days lasting 15 minutes and 52 seconds. Measurements in working memory use Operation Span Task, Reading Span Task and Symmetry Span Task. The design of the study used a pre-test post-test control group and the data were analyzed by t-test. The results showed a significant difference between the control group and the experimental group on the symmetry span task subtest (p = 0.044, p <0.05)

PERANCANGAN APLIKASI DASHBOARD WMS BERBASIS WEB SERVICE DENGAN MENGGUNAKAN TEKNOLOGI .NET WEB SERVICE DAN PHP

Warehouse Management System needs an item inventory, configuration saving method of items, integration among warehouses, and warehouse finance control. All of the aspects must be well arranged, in order to avoid warehouses’s work performance decrease that can affect to supply chain profit. To avoid the supply chain from losses, a warehouses need a system that can help to maintain and manage all of warehouse’s variables. A system that can implemented is WMS Dashboard. WMS Dashboard is an application that can show the warehouse’s data realtime and with high accuration. WMS Dashboard’s services are made by using ASP.NET Web Service Technology which use SOAP protocol and WSDL interface so it support multi platform system to system communication which using HTTP protocol. The database of WMS Dashboard is made by using MS SQL Server DBMS which has fully compatibility with other applications that made by .NET Framework. Object oriented PHP is need to made the application for client side. WSDL of WMS dashboard application consist of 56 services. The services has been integrated with WMS Dashboard Application which based on PHP, so it would be accessed easily, and it can be used to help maintain and manage the Warehouse System variables

THE EFFECT OF ETHANOLIC EXTRACT OF CENTELLA ASIATICA (L) URBAN ADMINISTRATION TOWARDS THE THICKNESS OF PYRAMIDAL LAYER IN THE CA1 REGION OF HIPPOCAMPUS OF SPRAGUE DAWLEY RATS AFTER CHRONIC RESTRAIN STRESS

Background: Stress has been shown can change the structure of the brain, especially in the cornu ammonic (CA) I region of hippocampus. Centella asiatica or pegagan as herbal neuroprotector was investigated. The study aimed to determine the effect of ethanolic extract of C. asiatica to the thickness of pyramidal layer in the CA1 region in rats subjected to chronic restrain stress (CRS). Method: This experimental study used post test only group design. Thirty five rats were divided into 6 groups: non stress group (control) and stress only group pulvis gum arabicum (PGA), positive control group (treated with fluoxetin 10mg/kgBW), and 3 treatment groups are treated with C. asiatica 150, 300, and 600mg/kgBW respectively. All groups except non stress group were subjected to CRS, for 6 hours per day for 21 days. Fluoxetin, PGA, and C. Asiatica were applied 30 minutes before CRS done. Rats were sacrificed at the end of 24th day and were perfused transcardially. Processed brain tissue stained with toluidine blue, and measured with Image Raster program. Result: The thickness of pyramidal layer in the CA1 region are increasing significantly in treatment groups which treated with 150 and 300 kg/BW of C. asiatica, but not significant which treated with 600mg/kgBW ethanolic extract of C. asiatica. Conclusion: Ethanolic extract of C. asiatica can improve thickness of pyramidal layer in the CA1 region of hippocampus of Sprague Dawley rats after chronic restrain stress. [JuKe Unila 2014; 4(8):202-207

The effect of listening to Holy Quran recitation on stress among healthy adults: a non-blinded randomized controlled trial

Background Stress is the body’s inability to reach a balance between physical or psychological demands and the ability to meet them. Failure to meet these demands has a crucial impact which includes physical, emotional, and behavioral disorders. Recitation of the Quran is believed to cause relaxation by lowering adrenocorticotropic and cortisol hormonal levels. This study aimed to assess the effects of Quran recitation on stress levels using the biofeedback indicators electromyogram, skin conductance, and heart rate among healthy adults. Methods This study used a pre- and post-test group design involving 40 males between 19 and 23 years of age, randomized into two groups, i.e. control group (n=20) and Quran recitation listeners (n=20). The subjects were conditioned in a quiet room for 30 minutes before the stress level measurements were taken. The stress level measurements by means of electromyogram, skin conductance, and heart rate were performed with biofeedback before and after giving the stressor tests’ protocol. Statistical analysis using independent t-test was then performed. Results The baseline comparative measurement using biofeedback between control and treatment groups revealed nonsignificant between-group differences in electromyogram, skin conductance, and heart rate (p=0.150; p= 0.389; and p=0.985 respectively). After applying the stress protocol followed by the intervention, the independent t-test revealed significant between-group differences in electromyogram and skin conductance (p= 0.042 and p=0.030), but not in heart rate (p=0.741). Conclusions Our study demonstrated that Quran recitation has a significant effect in relieving stress levels assessed using biofeedback parameters (electromyogram and skin conductance) among healthy adults