Black History Month at The Art Institute of Atlanta Library

The 2023 Black History Month program at The Art Institute of Atlanta is described. The program entailed the use of LibGuides to assist students in identifying figures in African American history, specifically individuals who were pioneers in the students\u27 fields of study. Students were provided access to a large paper banner to create tributes to the figures they discovered using the LibGuide

Yes, Virginia, There Are Full-Text Articles in That Bound Periodical!: Helping Students Make Connections About Locating Journal Articles

The overall theme of the program concerns the methods of instruction librarians are using to teach basic information about the following: journal formats, such as current, bound, microfilm, and electronic; elements of journal citations, such as publication date, volume numbers, and issue numbers; and why it is essential for students to understand this information in order to locate articles in print and electronic formats. The presenters will discuss their experiences and active learning activities used to introduce journal formats, the elements of journal citations, and journal locator tools, such as EBSCO A to Z and SFX, during library instruction sessions. They will also discuss the results of a survey administered to instruction librarians in the southeast regarding the methods used in teaching the elements of a journal citation and how they are used in locating articles in the library and in full-text electronic databases. Finally, the presenters will initiate a discussion with the program attendees to share their experiences teaching patrons about journal formats, elements of journal citations, and journal locator tools

Pengaruh Citra Merek, Kualitas Layanan dan Harga terhadap Keputusan Pembelian Tiket Lion Air

Penelitian ini dilatarbelakangi oleh peramalahan yang dihadapi Lion Air dalam segi citra merek, kualitas layanan dan harga. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh citra merek, kualitas layanan dan harga terhadap keputusan pembelian Tiket Lion Air. Jenis penelitian ini adalah kuantitatif dengan metode survei. Sampel dalam penelitian ini sebanyak 101 orang responden yang diambil dengan teknik non probability sampling. Teknik pengolahan data menggunakan program spss 20 dengan menggunakan beberapa pengolahan uji data, yaitu uji validitas, uji reliabilitas dan uji hipotesis. Hasil pengujian menunjukan bahwa secara parsial citra merek, kualitas layanan dan harga berpengaruh positif dan signifikan terhadap keputusan pembelian tiket Lion Ai

Impact of bidirectional relationships between streptococcus anginosus group and host tissue matrix components on cellular activity: Role in establishment of infection

This paper investigates pathogenic mechanisms of the Streptococcus anginosus group (SAG) of bacteria which influence the biological activity of periodontal ligament (PDL) cells, endothelial cells and also how matrix proteins produced by these host cells influence bacterial virulence factors. Isolates of SAG species, designated S. anginosus, S. constellatus and S. intermedius, were derived from healthy commensal and clinical pathogenic infection sites. SAG culture supernatants contained multiple protein components which differed between isolates. All SAG supernatants increased cellular proliferation and decreased decorin synthesis and collagen assembly by PDL cells and reduced endothelial cell migration. SAG isolates responded differently to extracellular matrix (ECM) components synthesised by PDL cells, but there was an overall notable increase in hydrolytic enzyme activity and in the production of the cytotoxin intermedilysin by S. intermedius. Collectively, the results indicate that both commensal and pathogenic SAG isolates were capable of impairing the ability of PDL cells and endothelial cells to make functional vascularised tissue. Reduced decorin synthesis is likely to have a major impact on cell signalling, angiogenesis and matrix assembly. Furthermore, ECM components produced by PDL cells were differentially capable of moderately increasing SAG enzymic activity, leading to subtle ECM modifications. The impact this bidirectional effect has on the tissue remodelling process is discussed

Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosis

Tachyzoite to bradyzoite development in Toxoplasma is marked by major changes in gene expression resulting in a parasite that expresses a new repertoire of surface antigens hidden inside a modified parasitophorous vacuole called the tissue cyst. The factors that control this important life cycle transition are not well understood. Here we describe an important transcriptional repressor mechanism controlling bradyzoite differentiation that operates in the tachyzoite stage. The ApiAP2 factor, AP2IV-4, is a nuclear factor dynamically expressed in late S phase through mitosis/cytokinesis of the tachyzoite cell cycle. Remarkably, deletion of the AP2IV-4 locus resulted in the expression of a subset of bradyzoite-specific proteins in replicating tachyzoites that included tissue cyst wall components BPK1, MCP4, CST1 and the surface antigen SRS9. In the murine animal model, the mis-timing of bradyzoite antigens in tachyzoites lacking AP2IV-4 caused a potent inflammatory monocyte immune response that effectively eliminated this parasite and prevented tissue cyst formation in mouse brain tissue. Altogether, these results indicate that suppression of bradyzoite antigens by AP2IV-4 during acute infection is required for Toxoplasma to successfully establish a chronic infection in the immune-competent host