2,553 research outputs found

    The CILIP/ESU Travelling Librarian Returns from South Africa

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    In fulfilment of the Travelling Librarian CILIP/ESU Award (2014) I visited Cape Town, Pretoria and Johannesburg in March 2015. The objective was to examine the role of librarians in facilitating forms of literacy and related ICT support, both on and off campus. I met with library professionals and academics from Cape Peninsula University of Technology (CPUT), the University of Pretoria (UP), University of Johannesburg (UJ) and Wits University. I also met with representatives from non- governmental organisations (NGO’s) such as Project Literacy and independent educators who are undertaking stellar literacy drives in local communities and townships. I was there for just over two weeks and it was a packed programme

    “New Kid on the Block”: the Black Cultural Archives (BCA) reflections on what it means for British History from here...

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    When I started studying history I was entranced by the big events; the invasions, battles, wars, and the big characters; the adventurers, aristocrats, rebels and revolutionaries, imperialists. I was also fascinated by the everyday people and individuals that managed to subvert formidable forces often placed in their way. These stories and historical narratives that we are so familiar with are undergirded by excellent historical sources accessible and held in institutions up and down the country that preserve and maintain the material for researchers. They help us understand the trajectory of this nation state because of Britain’s unique imperial and colonial past. We have increasing clarity regarding the actions of the establishment and its adventuring workers who sought their fortunes abroad. Moreover we can tell foreign visitors more about their historical heritage than they may be aware. We hold more of their historical “data” in our centres of learning, private collections and LMAs s than they hold on us

    MULTIVARIATE STATISTICAL ANALYSIS OF COLEOPTERA SPECTRAL REFLECTANCE

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    The insect order Coleoptera, commonly known as beetles, comprises 40% of all insects which in turn account for half of all identified animal species alive today. Coleopterans frequently have large elytra (the hardened front wings) that can have a wide range of colors. Spectral reflectance readings from these elytra may be used to uniquely identify coleopteran taxonomic groups. Multiple samples of eleven species of wood boring beetles were selected from the University of Idaho William Barr Entomology Museum. Spectrometer readings for each specimen were then fit to normal distribution mixture models to identify multiple peak reflectance wavelengths. Eighteen prominent peaks were identified across all taxonomic groups and genders creating a multivariate response structure. Multivariate statistical procedures including principal component and discriminant analyses were employed to assess the differentiation of taxonomic groups and genders based on spectral reflectance. The first three axes of the principal component analysis accounted for 96% of the variation and provided a clear clustering of genus and gender for a subset of taxonomic groups. The linear discriminant analysis under an assumption of multivariate normality provided a distinct classification of taxonomic groups resulting in an overall 4% misclassification rate; while the nearest neighbor discriminant analysis with a proportional prior gave an overall error rate of 5.2%. Internal bootstrap validation of the latter discriminant model yielded an average error rate of 3.5%. An external cross validation of the same model, conducted on independent samples of the same species with new individuals resulted in an average misclassification error rate of only 6.5%. Given the low error rates of misclassification, such multivariate statistical approaches are recommended for analysis of spectral reflectance in Coleoptera and other similar insect groups

    Cardiovascular risk assessments at occupational health services: employee experiences

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    Background: Across England in the UK, population screening for cardiovascular disease (CVD) primarily takes place within general practice in the form of the National Health Service Health Check. Additional screening sites such as occupational health are advocated to improve the population impact. Aims: To investigate participant experiences with cardiovascular and type 2 diabetes risk assessment (RA) at occupational health and subsequent support-seeking at general practice. Methods: Face-to-face interviews were conducted for this qualitative study. Participants were recruited at three workplaces; a steel works and two hospital sites. Using interpretive phenomenological analyses, themes were drawn from salient narratives and categorically organized. Results: There were 29 participants. Themes (n = 16) were organized into two domains; factors that facilitated (n = 9) or thwarted (n = 7) participant engagement with the RA and general practice. All participants described the RA as worthwhile and strongly valued RA at occupational health. Those with obesity and high CVD risk highlighted their difficulties in making lifestyle changes. Participants reported confusion and anxiety when GP advice about medication appeared to contradict what participants had interpreted during RA at occupational health. Conclusions: This study highlights factors that facilitate or thwart engagement in cardiovascular RA at occupational health services and general practice follow-up. Stakeholders can integrate these factors into standard operating procedures to enhance participant engagement and enable safeguards that minimize potential harm to participants

    Nova Sagittarii 1998 (V4633 Sgr) - a permanent superhump system or an asynchronous polar?

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    We report the results of observations of V4633 Sgr (Nova Sagittarii 1998) during 1998-2000. Two photometric periodicities were present in the light curve during the three years of observations: a stable one at P=3.014 h, which is probably the orbital period of the underlying binary system, and a second one of lower coherence, approximately 2.5 per cent longer than the former. The latter periodicity may be a permanent superhump, or alternatively, the spin period of the white dwarf in a nearly synchronous magnetic system. A third period, at P=5.06 d, corresponding to the beat between the two periods was probably present in 1999. Our results suggest that a process of mass transfer took place in the binary system since no later than two and a half months after the nova eruption. We derive an interstellar reddening of E(B-V)~0.21 from our spectroscopic measurements and published photometric data, and estimate a distance of d~9 kpc to this nova.Comment: 13 pages, latex, 7 figures, accepted for publication in MNRA

    Orally Delivered β-Glucans Aggravate Dextran Sulfate Sodium (DSS)-Induced Intestinal Inflammation

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    β-Glucans have beneficial health effects due to their immune modulatory properties. Oral administration of β-glucans affects tumour growth, microbial infection, sepsis, and wound healing. We hypothesized that pre-treatment with orally delivered soluble and particulate β-glucans could ameliorate the development of aggravate dextran sulfate sodium (DSS) induced intestinal inflammation. To study this, mice were orally pre-treated with β-glucans for 14 days. We tested curdlan (a particulate β-(1,3)-glucan), glucan phosphate (a soluble β-(1,3)-glucan), and zymosan (a particle made from Saccharomyces cerevisiae, which contains around 55% β-glucans). Weight loss, colon weight, and feces score did not differ between β-glucan and vehicle treated groups. However, histology scores indicated that β-glucan-treated mice had increased inflammation at a microscopic level suggesting that β-glucan treatment worsened intestinal inflammation. Furthermore, curdlan and zymosan treatment led to increased colonic levels of inflammatory cytokines and chemokines, compared to vehicle. Glucan phosphate treatment did not significantly affect cytokine and chemokine levels. These data suggest that particulate and soluble β-glucans differentially affect the intestinal immune responses. However, no significant differences in other clinical colitis scores between soluble and particulate β-glucans were found in this study. In summary, β-glucans aggravate the course of dextran sulfate sodium (DSS)-induced intestinal inflammation at the level of the mucosa

    Isospin-Violating Meson-Nucleon Vertices as an Alternate Mechanism of Charge-Symmetry Breaking

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    We compute isospin-violating meson-nucleon coupling constants and their consequent charge-symmetry-breaking nucleon-nucleon potentials. The couplings result from evaluating matrix elements of quark currents between nucleon states in a nonrelativistic constituent quark model; the isospin violations arise from the difference in the up and down constituent quark masses. We find, in particular, that isospin violation in the omega-meson--nucleon vertex dominates the class IV CSB potential obtained from these considerations. We evaluate the resulting spin-singlet--triplet mixing angles, the quantities germane to the difference of neutron and proton analyzing powers measured in elastic np\vec{n}-\vec{p} scattering, and find them commensurate to those computed originally using the on-shell value of the ρ\rho-ω\omega mixing amplitude. The use of the on-shell ρ\rho-ω\omega mixing amplitude at q2=0q^2=0 has been called into question; rather, the amplitude is zero in a wide class of models. Our model possesses no contribution from ρ\rho-ω\omega mixing at q2=0q^2=0, and we find that omega-meson exchange suffices to explain the measured npn-p analyzing power difference~at~183 MeV.Comment: 20 pages, revtex, 3 uuencoded PostScript figure

    Occurrence of subdural hematomas in Dutch glutaric aciduria type 1 patients

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    Patients with glutaric aciduria type 1 (GA1), a rare inherited metabolic disorder, have an increased risk for subdural hematomas (SDHs). GA1 is therefore generally included in the differential diagnosis of children presenting with SDHs. This retrospective cohort study reviews all 25 registered, in the Dutch Diagnosis Registration for Metabolic Disorders, GA1 patients in the Netherlands. This was done between May 2014 and November 2014 to determine the lifetime incidence of SDHs in this population. Seventeen patients were diagnosed either due to clinical symptoms or because of family members with GA1. One out of these 17 had a SDH. This patient showed widened Sylvian fissures on MRI, characteristic for GA1. Eight patients were diagnosed by newborn screening. Three of them had neuroimaging results, and none of them had SDHs. This study shows an overall lower incidence (4.0 %) of SDHs in patients with GA1 than reported in the literature (20–30 %). Conclusion: This finding, in combination with the fact that SDHs in GA1 appear to occur only in the presence of characteristic brain abnormalities on imaging, we recommend that GA1 should not routinely be a part of the differential diagnosis of children with unexplained SDHs in the absence of imaging characteristics suggestive of GA1. What is known:• Glutaric aciduria type 1 is a rare metabolic disorder predisposing children to subdural hematoma development due to brain abnormalities.• Because of these subdural hematomas, glutaric aciduria type 1 testing is part of abusive head trauma work-up.What is new:• The overall subdural hematoma incidence in glutaric aciduria type 1 patients is much lower than previously reported and only occurs in case of predisposing brain abnormalities

    A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot

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    From observational studies, farmers who use parenteral antibacterials to promptly treat all sheep with footrot (FR) or interdigital dermatitis (ID) have a prevalence of lameness of <2% compared with a prevalence of 9% lameness reported by farmers who treat lame sheep by trimming affected feet. We tested the hypothesis that prompt treatment of sheep lame with naturally developing FR or ID with parenteral and topical antibacterials reduces the prevalence and incidence of lameness with these conditions compared with less frequent treatment with trimming of hoof horn and applying topical antibacterials. A further hypothesis was that reduction of ID and FR would improve productivity. A lowland sheep flock with 700 ewes was used to test these hypotheses in an 18-month within farm clinical trial with four groups of ewes: two intervention and two control. The duration and severity of lameness was used to categorise sheep into three weighted scores of lameness (WLS): never lame (WLS0), mildly lame/lame for <6 days (WLS1) and severely or chronically lame (WLS2). The intervention reduced the prevalence of lameness due to FR and ID in ewes and lambs and the incidence of lameness in ewes. The WLS was also significantly lower in sheep in the intervention groups. Ewes with a higher WLS were subsequently significantly more likely to have a body condition score <2.5 and to have lame lambs. Significantly more ewes lambed and successfully reared more lambs that were ready for slaughter at a younger age in the intervention versus control groups. There was an increase in the gross margin of £630/100 ewes mated in the intervention group, including the cost of treatment of £150/100 ewes mated. We conclude that prompt parenteral and topical antibacterial treatment of sheep lame with ID and FR reduced the prevalence and incidence of these infectious conditions and led to improved health, welfare and productivity
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