East African topography and volcanism explained by a single, migrating plume

Anomalous topographic swells and Cenozoic volcanism in east Africa have been associated with mantle plumes. Several models involving one or more fixed plumes beneath the northeastward migrating African plate have been suggested to explain the space-time distribution of magmatism in east Africa. We devise paleogeographically constrained global models of mantle convection and, based on the evolution of flow in the deepest lower mantle, show that the Afar plume migrated southward throughout its lifetime. The models suggest that the mobile Afar plume provides a dynamically consistent explanation for the spatial extent of the southward propagation of the east African rift system (EARS), which is difficult to explain by the northeastward migration of Africa over one or more fixed plumes alone, over the last ≈45 Myrs. We further show that the age-progression of volcanism associated with the southward propagation of EARS is consistent with the apparent surface hotspot motion that results from southward motion of the modelled Afar plume beneath the northeastward migrating African plate. The models suggest that the Afar plume became weaker as it migrated southwards, consistent with trends observed in the geochemical record

Perspectives on subnational carbon and climate footprints: A case study of Southampton, UK

Sub-national governments are increasingly interested in local-level climate change management. Carbon- (CO2 and CH4) and climate-footprints—(Kyoto Basket GHGs) (effectively single impact category LCA metrics, for global warming potential) provide an opportunity to develop models to facilitate effective mitigation. Three approaches are available for the footprinting of sub-national communities. Territorial-based approaches, which focus on production emissions within the geo-political boundaries, are useful for highlighting local emission sources but do not reflect the transboundary nature of sub-national community infrastructures. Transboundary approaches, which extend territorial footprints through the inclusion of key cross boundary flows of materials and energy, are more representative of community structures and processes but there are concerns regarding comparability between studies. The third option, consumption-based, considers global GHG emissions that result from final consumption (households, governments, and investment). Using a case study of Southampton, UK, this chapter develops the data and methods required for a sub-national territorial, transboundary, and consumption-based carbon and climate footprints. The results and implication of each footprinting perspective are discussed in the context of emerging international standards. The study clearly shows that the carbon footprint (CO2 and CH4 only) offers a low-cost, low-data, universal metric of anthropogenic GHG emission and subsequent management

Does a monetary incentive improve the response to a postal questionnaire in a randomised controlled trial? : the MINT incentive study

Background: Sending a monetary incentive with postal questionnaires has been found to improve the proportion of responders, in research in non-healthcare settings. However, there is little research on use of incentives to improve follow-up rates in clinical trials, and existing studies are inconclusive. We conducted a randomised trial among participants in the Managing Injuries of the Neck Trial (MINT) to investigate the effects on the proportion of questionnaires returned and overall non-response of sending a £5 gift voucher with a follow-up questionnaire. Methods: Participants in MINT were randomised to receive either: (a) a £5 gift voucher (incentive group) or (b) no gift voucher (no incentive group), with their 4 month or 8 month follow-up questionnaire. We recorded, for each group, the number of questionnaires returned, the number returned without any chasing from the study office, the overall number of non-responders (after all chasing efforts by the study office), and the costs of following up each group. Results: 2144 participants were randomised, 1070 to the incentive group and 1074 to the no incentive group. The proportion of questionnaires returned (RR 1.10 (95% CI 1.05, 1.16)) and the proportion returned without chasing (RR 1.14 (95% CI 1.05, 1.24) were higher in the incentive group, and the overall non-response rate was lower (RR 0.68 (95% CI 0.53, 0.87)). Adjustment for injury severity and hospital of recruitment to MINT made no difference to these results, and there were no differences in results between the 4-month and 8-month follow up questionnaires. Analysis of costs suggested a cost of £67.29 per additional questionnaire returned. Conclusion: Monetary incentives may be an effective way to increase the proportion of postal questionnaires returned and minimise loss to follow-up in clinical trials

Sleep behaviour relates to language skills in children with and without communication disorders

BACKGROUND: Sleep problems are common in children with autism spectrum disorder (ASD). There is also emerging evidence that sleep quality influences language learning in typical development. However there is a gap within the literature in regards to sleep and developmental language disorder in children (DLD). OBJECTIVES: The aims of this study were to: i) compare sleep patterns of children with communication disorders to the sleep patterns of their typical peers, and ii) ascertain whether sleep patterns related to language in this sample. METHOD: The relationship between sleep and language was investigated via parental questionnaires. There were sixty-five child participants in total aged between 3-18 years. Parents reported on 28 children with a developmental communication disorder (CD; ASD n=8 or DLD n=20) and 37 who were typical developing. RESULTS: The children with a developmental communication disorder showed more sleep problems than their typical peers particularly in terms of getting to sleep and early waking. Furthermore, significant correlations were found between sleep behaviour and language for children in both groups. CONCLUSION: Children with CD may have poorer sleep patterns than their typical peers which could compound developmental language difficulties

East African topography and volcanism explained by a single, migrating plume

Anomalous topographic swells and Cenozoic volcanism in east Africa have been associated with mantle plumes. Several models involving one or more fixed plumes beneath the northeastward migrating African plate have been suggested to explain the space-time distribution of magmatism in east Africa. We devise paleogeographically constrained global models of mantle convection and, based on the evolution of flow in the deepest lower mantle, show that the Afar plume migrated southward throughout its lifetime. The models suggest that the mobile Afar plume provides a dynamically consistent explanation for the spatial extent of the southward propagation of the east African rift system (EARS), which is difficult to explain by the northeastward migration of Africa over one or more fixed plumes alone, over the last ≈45 Myrs. We further show that the age-progression of volcanism associated with the southward propagation of EARS is consistent with the apparent surface hotspot motion that results from southward motion of the modelled Afar plume beneath the northeastward migrating African plate. The models suggest that the Afar plume became weaker as it migrated southwards, consistent with trends observed in the geochemical record

C4-aldehyde of guaiazulene:synthesis and derivatisation

Guaiazulene is an alkyl-substituted azulene available from natural sources and is a much lower cost starting material for the synthesis of azulene derivatives than azulene itself. Here we report an approach for the selective functionalisation of guaiazulene which takes advantage of the acidity of the protons on the guaiazulene C4 methyl group. The aldehyde produced by this approach constitutes a building block for the construction of azulenes substituted on the seven-membered ring. Derivatives of this aldehyde synthesised by alkenylation, reduction and condensation are reported, and the halochromic properties of a subset of these derivatives have been studied.</p

A national survey of clinical practice for the management of whiplash-associated disorders in UK emergency departments

Objective: To undertake a national survey to determine current practice for the management of whiplash injuries in UK emergency departments (ED). Methods: Postal questionnaire survey. 316 lead consultants from all UK ED with annual new attendances of over 50 000 people were asked to indicate the use of a range of treatments and the frequency with which these treatments were used. Samples of written advice were requested and content analysis was conducted and compared with survey responses. Results: The response rate was 79% (251/316). The intervention most frequently used was verbal advice to exercise, reported by 84% of respondents for most or all cases, and advice against the use of a collar (83%). Other treatments reported as being used frequently were written advice and anti-inflammatory medication. 106 consultants (42%) provided a sample of written materials. Reference to expected recovery and encouragement for early return to activities were included in less than 6%. Nearly 50% of written materials contained information on how to use a soft collar and 61% contained information on solicitors and pursuing a personal injury claim. There were important differences between reported verbal behaviours and written advice. Conclusion: Verbal advice is the primary method for managing whiplash injuries in ED and is usually supplemented by written advice. Within individual hospitals there is a lack of consistency between verbal and written advice. The promotion of personal injury claims is a common feature of written advice. Research is required to develop effective and consistent models of advice

A Global Plate Model Including Lithospheric Deformation Along Major Rifts and Orogens Since the Triassic

Global deep‐time plate motion models have traditionally followed a classical rigid plate approach, even though plate deformation is known to be significant. Here we present a global Mesozoic–Cenozoic deforming plate motion model that captures the progressive extension of all continental margins since the initiation of rifting within Pangea at ~240 Ma. The model also includes major failed continental rifts and compressional deformation along collision zones. The outlines and timing of regional deformation episodes are reconstructed from a wealth of published regional tectonic models and associated geological and geophysical data. We reconstruct absolute plate motions in a mantle reference frame with a joint global inversion using hot spot tracks for the last 80 million years and minimizing global trench migration velocities and net lithospheric rotation. In our optimized model, net rotation is consistently below 0.2°/Myr, and trench migration scatter is substantially reduced. Distributed plate deformation reaches a Mesozoic peak of 30 × 106 km2 in the Late Jurassic (~160–155 Ma), driven by a vast network of rift systems. After a mid‐Cretaceous drop in deformation, it reaches a high of 48 x 106 km2 in the Late Eocene (~35 Ma), driven by the progressive growth of plate collisions and the formation of new rift systems. About a third of the continental crustal area has been deformed since 240 Ma, partitioned roughly into 65% extension and 35% compression. This community plate model provides a framework for building detailed regional deforming plate networks and form a constraint for models of basin evolution and the plate‐mantle system

Dynamic topography of passive continental margins and their hinterlands since the Cretaceous

Even though it is well accepted that the Earth\u27s surface topography has been affected by mantle-convection induced dynamic topography, its magnitude and time-dependence remain controversial. The dynamic influence to topographic change along continental margins is particularly difficult to unravel, because their stratigraphic record is dominated by tectonic subsidence caused by rifting. We follow a three-fold approach to estimate dynamic topographic change along passive margins based on a set of seven global mantle convection models. We first demonstrate that a geodynamic forward model that includes adiabatic and viscous heating in addition to internal heating from radiogenic sources, and a mantle viscosity profile with a gradual increase in viscosity below the mantle transition zone, provides a greatly improved match to the spectral range of residual topography end-members as compared with previous models at very long wavelengths (spherical degrees 2-3). We then combine global sea level estimates with predicted surface dynamic topography to evaluate the match between predicted continental flooding patterns and published paleo-coastlines by comparing predicted versus geologically reconstructed land fractions and spatial overlaps of flooded regions for individual continents since 140 Ma. Modelled versus geologically reconstructed land fractions match within 10% for most models, and the spatial overlaps of inundated regions are mostly between 85% and 100% for the Cenozoic, dropping to about 75-100% in the Cretaceous. Regions that have been strongly affected by mantle plumes are generally not captured well in our models, as plumes are suppressed in most of them, and our models with dynamically evolving plumes do not replicate the location and timing of observed plume products. We categorise the evolution of modelled dynamic topography in both continental interiors and along passive margins using cluster analysis to investigate how clusters of similar dynamic topography time series are distributed spatially. A subdivision of four clusters is found to best reveal end-members of dynamic topography evolution along passive margins and their hinterlands, differentiating topographic stability, long-term pronounced subsidence, initial stability over a dynamic high followed by moderate subsidence and regions that are relatively proximal to subduction zones with varied dynamic topography histories. Along passive continental margins the most commonly observed process is a gradual motion from dynamic highs towards lows during the fragmentation of Pangea, reflecting the location of many passive margins now over slabs sinking in the lower mantle. Our best-fit model results in up to 500 (± 150) m of total dynamic subsidence of continental interiors while along passive margins the maximum predicted dynamic topographic change over 140 million years is about 350 (± 150) m of subsidence. Models with plumes exhibit clusters of transient passive margin uplift of about 200 ± 200 m, but are mainly characterised by long-term subsidence of up to 400 m. The good overall match between predicted dynamic topography to geologically mapped paleo-coastlines makes a convincing case that mantle-driven topographic change is a critical component of relative sea level change, and indeed the main driving force for generating the observed geometries and timings of large-scale continental inundation through time