Assessing the level of spatial homogeneity of the agronomic Indian monsoon onset

Over monsoon regions, such as the Indian subcontinent, the local onset of persistent rainfall is a crucial event in the annual climate for agricultural planning. Recent work suggested that local onset dates are spatially coherent to a practical level over West Africa; a similar assessment is undertaken here for the Indian subcontinent. Areas of coherent onset, defined as local onset regions or LORs, exist over the studied region. These LORs are significant up to the 95% confidence interval and are primarily clustered around the Arabian Sea (adjacent to and extending over the Western Ghats), the Monsoon Trough (north central India), and the Bay of Bengal. These LORs capture regions where synoptic scale controls of onset may be present and identifiable. In other regions, the absence of LORs is indicative of regions where local and stochastic factors may dominate onset. A potential link between sea surface temperature anomalies and LOR variability is presented. Finally, Kerala, which is often used as a representative onset location, is not contained within an LOR suggesting that variability here may not be representative of wider onset variability

Treatment response in child anxiety is differentially related to the form of maternal anxiety disorder

An examination was made of the extent to which maternal anxiety predicted response to treatment of children presenting with an anxiety disorder. In a sample of 55 children referred to a local NHS CAMH service for treatment of an anxiety disorder, systematic mental state interview assessment was made of both mothers and children, and both completed self-report questionnaires to assess aspects of anxiety, both immediately before the children received treatment and following treatment. Children of mothers with anxiety disorder overall responded less well to treatment than children of mothers with no anxiety disorder. There was some diagnostic specificity in this in that children of mothers with GAD did as well in treatment as children whose mothers had no anxiety, whereas children of mothers with social phobia did poorly. The outcome for children with anxiety appears to be related to the presence and nature of maternal anxiety. It would seem prudent that treatment of children with anxiety involves assessment of maternal anxiety. It is important to establish in systematic investigation whether treatment of maternal anxiety improves the outcome for child anxiety

Seeking the Goal in the Process, the Process for the Goal: Organizational Learning in a Public Sector Change Project

This paper describes how a combination of process modelling and goal modelling techniques has been used to facilitate organizational learning. The case study comes from the public sector in the UK. The modelling techniques have helped users to rationalise about the existing processes and then to design how they would like the process to work. The paper describes how the users have been able to confront the complex issues involved. The experience suggests that the combination of the modelling techniques is important to the learning experience of the users involved

Who Owns Europe?... and why it matters for Progressives

First paragraph: Ownership matters. Owners of businesses set their strategic direction, purpose and the terms of employment. Owners of land decide what should be done with it and who can access it. Owners of property decide how it is deployed and who can enjoy its benefits. These decisions have a profound impact on the rest of European economy and society. Too often when we try to understand who owns the assets on which we all rely, the beneficial owners are obscured, and capital is controlled by owners whose interests are divergent from the citizenry at large. Politicians rarely consider questions of ownership when making policy, but the frameworks that they establish for market economies have a profound effect on the levels of corporate plurality in business, and ultimately the outcomes for citizens. Progressives must offer a thoughtful critique which ensures that the benefits of ownership are not concentrated in the hands of the few. Policy should facilitate a fair ownership opportunity for all. This project seeks to examine ownership across the EU, it considers how Europe’s businesses are owned and where the benefits of business flow. It looks closely at different types of ownership model, for example - the joint-stock company, the private business, the partnership model and the mutually-owned enterprise. At the same time, it is concerned with ownership more widely. Who owns the land on which our produce is grown, the apartment blocks in which we live and the institutions in which we store our earnings? We have examined whether some forms of ownership are more conducive to the public good and to what extent public goals can be discharged by a wider range of ownership types. Ownership in the public interest can be achieved, but it requires a consistent approach across EU member states, with policy, legislative and regulatory frameworks that support and protect ownership that is designed for a common purpose, rather than simply focussed on maximising private profit. This report makes a series of recommendations which seek to ensure strong economies which are purposeful and successful, but which also benefit the wider public good

Who Owns Europe?... and why it matters for Progressives

First paragraph: Ownership matters. Owners of businesses set their strategic direction, purpose and the terms of employment. Owners of land decide what should be done with it and who can access it. Owners of property decide how it is deployed and who can enjoy its benefits. These decisions have a profound impact on the rest of European economy and society. Too often when we try to understand who owns the assets on which we all rely, the beneficial owners are obscured, and capital is controlled by owners whose interests are divergent from the citizenry at large. Politicians rarely consider questions of ownership when making policy, but the frameworks that they establish for market economies have a profound effect on the levels of corporate plurality in business, and ultimately the outcomes for citizens. Progressives must offer a thoughtful critique which ensures that the benefits of ownership are not concentrated in the hands of the few. Policy should facilitate a fair ownership opportunity for all. This project seeks to examine ownership across the EU, it considers how Europe’s businesses are owned and where the benefits of business flow. It looks closely at different types of ownership model, for example - the joint-stock company, the private business, the partnership model and the mutually-owned enterprise. At the same time, it is concerned with ownership more widely. Who owns the land on which our produce is grown, the apartment blocks in which we live and the institutions in which we store our earnings? We have examined whether some forms of ownership are more conducive to the public good and to what extent public goals can be discharged by a wider range of ownership types. Ownership in the public interest can be achieved, but it requires a consistent approach across EU member states, with policy, legislative and regulatory frameworks that support and protect ownership that is designed for a common purpose, rather than simply focussed on maximising private profit. This report makes a series of recommendations which seek to ensure strong economies which are purposeful and successful, but which also benefit the wider public good

A View from the Top: International Politics, Norms and the Worldwide Growth of NGOs

This article provides a top-down explanation for the rapid growth of nongovernmental organizations (NGOs) in the postwar period, focusing on two aspects of political globalization. First, I argue that international political opportunities in the form of funding and political access have expanded enormously in the postwar period and provided a structural environment highly conducive to NGO growth. Secondly, I present a norm-based argument and trace the rise of a pro-NGO norm in the 1980s and 1990s among donor states and intergovernmental organizations (IGOs), which has actively promoted the spread of NGOs to non-Western countries. The article ends with a brief discussion of the symbiotic relationship among NGOs, IGOs, and states promoting international cooperation

Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells

A wide range of molecules acting as apoptotic cell-associated ligands, phagocyte-associated receptors or soluble bridging molecules have been implicated within the complex sequential processes that result in phagocytosis and degradation of apoptotic cells. Intercellular adhesion molecule 3 (ICAM-3, also known as CD50), a human leukocyte-restricted immunoglobulin super-family (IgSF) member, has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined. The main objective of this work is to further characterise the function of ICAM-3 in the removal of apoptotic cells. Using a range of novel anti-ICAM-3 monoclonal antibodies (mAbs), including one (MA4) that blocks apoptotic cell clearance by macrophages, alongside apoptotic human leukocytes that are normal or deficient for ICAM-3, we demonstrate that ICAM-3 promotes a domain 1–2-dependent tethering interaction with phagocytes. Furthermore, we demonstrate an apoptosis-associated reduction in ICAM-3 that results from release of ICAM-3 within microparticles that potently attract macrophages to apoptotic cells. Taken together, these data suggest that apoptotic cell-derived microparticles bearing ICAM-3 promote macrophage chemoattraction to sites of leukocyte cell death and that ICAM-3 mediates subsequent cell corpse tethering to macrophages. The defined function of ICAM-3 in these processes and profound defect in chemotaxis noted to ICAM-3-deficient microparticles suggest that ICAM-3 may be an important adhesion molecule involved in chemotaxis to apoptotic human leukocytes

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level