Angular Momentum Loss Mechanisms in Cataclysmic Variables below the Period Gap

Mass transfer in cataclysmic variables (CVs) is usually considered to be caused by angular momentum loss (AML) driven by magnetic braking and gravitational radiation (GR) above the period gap, and solely by GR below the period gap. The best-fit revised model of CV evolution recently by \citet{kbp11}, however, indicates that AML rate below the period gap is $2.47(\pm 0.22)$ times the GR rate, suggesting the existence of some other AML mechanisms. We consider several kinds of consequential AML mechanisms often invoked in the literature: isotropic wind from the accreting white dwarfs, outflows from the Langrangian points, and the formation of a circumbinary disk. We found that neither isotropic wind from the white dwarf nor outflow from the $L_1$ point can explain the extra AML rate, while ouflow from the $L_2$ point or a circumbinary disk can effectively extract the angular momentum provided that $\sim (15-45)$ of the transferred mass is lost from the binary. A more promising mechanism is a circumbinary disk exerting gravitational torque on the binary. In this case the mass loss fraction can be as low as $\lesssim 10^{-3}$.Comment: 16 pages, 6 figures, accepted for publication in Ap

A new extremely low-mass white dwarf in the NLTT catalogue

We report on the discovery of the extremely low-mass, hydrogen-rich white dwarf, NLTT 11748. Based on measurements of the effective temperature (8540+/-50 K) and surface gravity (log g = 6.20+/-0.15) obtained by fitting the observed Balmer line profiles with synthetic spectra, we derive a mass of 0.167+/-0.005 M_solar. This object is one of only a handful of white dwarfs with masses below 0.2 M_solar that are believed to be the product of close binary evolution with an episode of Roche lobe overflow onto a degenerate companion (neutron star or white dwarf). Assuming membership in the halo population, as suggested by the kinematics and adopting a cooling age of 4.0 - 6.3 Gyrs for the white dwarf, we infer a progenitor mass of 0.87 - 0.93 M_solar. The likely companion has yet to be identified, but a search for radial velocity variations may help constrain its nature.Comment: Accepted for publication in A&A Letter

Variance-constrained dissipative observer-based control for a class of nonlinear stochastic systems with degraded measurements

The official published version of the article can be obtained from the link below.This paper is concerned with the variance-constrained dissipative control problem for a class of stochastic nonlinear systems with multiple degraded measurements, where the degraded probability for each sensor is governed by an individual random variable satisfying a certain probabilistic distribution over a given interval. The purpose of the problem is to design an observer-based controller such that, for all possible degraded measurements, the closed-loop system is exponentially mean-square stable and strictly dissipative, while the individual steady-state variance is not more than the pre-specified upper bound constraints. A general framework is established so that the required exponential mean-square stability, dissipativity as well as the variance constraints can be easily enforced. A sufficient condition is given for the solvability of the addressed multiobjective control problem, and the desired observer and controller gains are characterized in terms of the solution to a convex optimization problem that can be easily solved by using the semi-definite programming method. Finally, a numerical example is presented to show the effectiveness and applicability of the proposed algorithm.This work was supported in part by the Distinguished Visiting Fellowship of the Royal Academy of Engineering of the UK, the Royal Society of the UK, the GRF HKU 7137/09E, the National Natural Science Foundation of China under Grant 61028008, the International Science and Technology Cooperation Project of China under Grant 2009DFA32050, and the Alexander von Humboldt Foundation of Germany

Integrated Modeling System for Water Resources Management of Tarim River Basin

An integrated modeling system has been developed for water resources management of the Tarim River Basin, China. The system coupled remote sensing (RS)/geography information system (GIS) technique with distributed hydrological model to simulate the rainfall runoff, snow melting, and evapotranspiration process of the hydrological cycle. A case study was carried out in the Kaidu watershed. RS/GIS technique was used for effectively accessing, processing, and managing spatial data, such as land use, vegetative cover, soil, topography, precipitation, and evapotranspiration. The model was calibrated and validated against observed discharge for two hydrological stations during the period 1998-2001, and it generally performed well for Nash-Sutcliffe coefficient, water balance coefficient, and correlation coefficient. The Nash-Sutcliffe coefficient was approximately over 0.7 and the water balance error was lower than +/- 5%, indicating reasonable prediction accuracy. A comparison between the conventional and RS-based hydrological models was conducted. Although the two-models exhibit similar performances on runoff and snow melt simulation, the RS-based hydrological model had better performance in the simulation of actual evapotranspiration. Modeling results provide useful decision support for water resources management

bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene

miR-23a, a member of the miR-23a/24-2/27a cluster, has been demonstrated to play pivotal roles in many cellular activities. However, the mechanisms of how bta-miR-23a controls the myogenic differentiation (MD) of PDGFRalpha(-) bovine progenitor cells (bPCs) remain poorly understood. In the present work, bta-miR-23a expression was increased during the MD of (PDGFRalpha-) bPCs. Moreover, bta-miR-23a overexpression significantly promoted the MD of (PDGFRalpha-) bPCs. Luciferase reporter assays showed that the 3\u27-UTR region of MDFIC (MyoD family inhibitor domain containing) could be a promising target of bta-miR-23a, which resulted in its post-transcriptional down-regulation. Additionally, the knockdown of MDFIC by siRNA facilitated the MD of (PDGFRalpha-) bPCs, while the overexpression of MDFIC inhibited the activating effect of bta-miR-23a during MD. Of note, MDFIC might function through the interaction between MyoG transcription factor and MEF2C promoter. This study reveals that bta-miR-23a can promote the MD of (PDGFRalpha-) bPCs through post-transcriptional downregulation of MDFIC

The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCFC^(dc4*)

Ubiquitin ligases, together with their cognate ubiquitin-conjugating enzymes, are responsible for the ubiquitylation of proteins, a process that regulates a myriad of eukaryotic cellular functions. The first cullin-RING ligase discovered, yeast SCF^(Cdc4), functions with the conjugating enzyme Cdc34 to regulate the cell cycle. Cdc34 orthologs are notable for their highly acidic C-terminal extension. Here we confirm that the Cdc34 acidic C-terminal tail has a role in Cdc34 binding to SCF^(Cdc4) and makes a major contribution to the submicromolar K_m of Cdc34 for SCF^(Cdc4). Moreover, we demonstrate that a key functional property of the tail is its acidity. Our analysis also uncovers an unexpected new function for the acidic tail in promoting catalysis. We demonstrate that SCF is functional when Cdc34 is fused to the C terminus of Cul1 and that this fusion retains partial function even when the acidic tail has been deleted. The Cdc34-SCF fusion proteins that lack the acidic tail must interact in a fundamentally different manner than unfused SCF and wild type Cdc34, demonstrating that distinct mechanisms of E2 recruitment to E3, as is seen in nature, can sustain substrate ubiquitylation. Finally, a search of the yeast proteome uncovered scores of proteins containing highly acidic stretches of amino acids, hinting that electrostatic interactions may be a common mechanism for facilitating protein assembly

High spatial resolution nanoslit SERS for single-molecule nucleobase sensing

Solid-state nanopores promise a scalable platform for single-molecule DNA analysis. Direct, real-time identification of nucleobases in DNA strands is still limited by the sensitivity and the spatial resolution of established ionic sensing strategies. Here, we study a different but promising strategy based on optical spectroscopy. We use an optically engineered elongated nanopore structure, a plasmonic nanoslit, to locally enable single-molecule surface enhanced Raman spectroscopy (SERS). Combining SERS with nanopore fluidics facilitates both the electrokinetic capture of DNA analytes and their local identification through direct Raman spectroscopic fingerprinting of four nucleobases. By studying the stochastic fluctuation process of DNA analytes that are temporarily adsorbed inside the pores, we have observed asynchronous spectroscopic behavior of different nucleobases, both individual and incorporated in DNA strands. These results provide evidences for the single-molecule sensitivity and the sub-nanometer spatial resolution of plasmonic nanoslit SERS

Is SN 2006X from a WD + MS system with optically thick wind?

The single-degenerate channel is widely accepted as the progenitors of type Ia supernovae (SNe Ia). Following the work of Meng, Chen and Han (2009), we reproduced the birth rate and age of supernovae like SN 2006X by the single-degenerate model (WD + MS) with an optically thick wind, which may imply that the progenitor of SN 2006X is a WD + MS system.Comment: 10 pages, 2 figures, accepted for publication in New

Skin Microvascular Thrombosis in Fusarium Infection in Two Early Biopsied Cases

Fusarium species cause rare and severe infections. Their incidence is increasing in immunocompromised patients but they are also observed in healthy hosts. Because of the rapid dissemination of infection and the frequent resistance of Fusarium species to antifungal drugs, histopathologic evidence of hyphae is very helpful to obtain the diagnosis rapidly. We report the clinical and pathological features of two patients with initial cutaneous lesions. Cutaneous early biopsies showed microvessel involvement with hyphae and thrombosis. Fusarium infection was confirmed by skin culture. Hyphae within a microvessel thrombus in the skin were highly suggestive of disseminated fungal infection. These pathological features enabled to establish an early diagnosis and to start efficient antifungal treatment. In early cutaneous biopsies of immunocompromised patients, the presence of cutaneous vessel thrombosis can suggest a fungal infection and may help to start specific therapy without delay for these life-threatening infections

White Dwarf/M Dwarf Binaries as Single Degenerate Progenitors of Type Ia Supernovae

Limits on the companions of white dwarfs in the single degenerate scenario for the origin of Type Ia supernovae (SNIa) have gotten increasingly tight. The only type of non-degenerate stars that survive the limits on the companions of SNIa in SNR 0509-67.5 and SN1572 are M dwarfs. M dwarfs have special properties that have not been considered in most work on the progenitors of SNIa: they have small but finite magnetic fields, and they flare frequently. These properties are explored in the context of SNIa progenitors. White dwarf/M dwarf pairs may be sufficiently plentiful to provide an adequate rate of explosions. Even modest magnetic fields on the white dwarf and M dwarf will yield adequate torques to lock the two stars together, resulting in a slowly rotating white dwarf, with the magnetic poles pointing at one another in the orbital plane. The mass loss will be channeled by a "magnetic bottle" connecting the two stars, landing on a concentrated polar area on the white dwarf. This enhances the effective rate of accretion compared to spherical accretion. Luminosity from accretion and hydrogen burning on the surface of the white dwarf may induce self-excited mass transfer. The combined effects of self-excited mass loss, polar accretion, and magnetic inhibition of mixing of accretion layers give possible means to beat the "nova limit" and grow the white dwarf to the Chandrasekhar mass even at rather moderate mass accretion rates.Comment: 32 pages, 4 figures, accepted for publication in the Astrophysical Journa