268 research outputs found

    Direct, Hands-on Or Inquiry Instruction A Study Of Instructional Sequencing And Motivation In The Science Classroom

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    Currently, a debate exists between the strengths and weaknesses of direct and inquiry instruction. Inquiry instruction is related to positive effect on learner motivation whereas supporters of direct instruction point to its ability to adequately support learners’ working memories (Hmelo-Silver, Duncan, & Chinn, 2007; Kirschner, Sweller, & Clark, 2006; Kuhn, 2007; Sweller, 1988). This study examined the possibility of combining the best features of both inquiry and direct instruction by sequencing them together. A two-part lesson on electrical circuits was presented in three separate sequences of instruction to middle school students to determine if differences in student motivation and academic achievement emerge depending on whether a guided inquiry lab followed or preceded direct instruction. Results indicated equal levels of perceived competence by students across all instructional sequences and greater interest/enjoyment and perceived autonomy support when the instructional sequence began with a guided inquiry lesson. No significant differences in achievement were reported among the sequences

    Precarious Vocations: The Subjectivation of Unemployment in Vocational Training and Career Services in West Germany and Great Britain 1964–1990

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    Customarily speaking, concepts of vocational and career training have been organised differently in Great Britain and the Federal Republic of Germany. Since the nineteenth century, vocation has been the “organising principle” of apprenticeship and vocational training in Germany, alongside of social security and other social forms. In Britain, however, a standardised system of vocational education and training does not exist. This paper seeks to shed light on a variety of systems for apprenticeship, vocational training, and career services in British and West German employment offices, as well as their effects on unemployment after the late 1960s.Customarily speaking, concepts of vocational and career training have been organised differently in Great Britain and the Federal Republic of Germany. Since the nineteenth century, vocation has been the “organising principle” of apprenticeship and vocational training in Germany, alongside of social security and other social forms. In Britain, however, a standardised system of vocational education and training does not exist. This paper seeks to shed light on a variety of systems for apprenticeship, vocational training, and career services in British and West German employment offices, as well as their effects on unemployment after the late 1960s

    Characteristics of Advocates: An Exploration of Skills and Skill Development Used in the Performance of Advocacy Work in the Mental Health Profession

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    This dissertation sought to explore the skills necessary to become an effective advocate in the mental health profession. Additionally, this study sought to discover how and where mental health professionals learned the necessary skills to be advocates. This qualitative study examined the factors identified by individuals actively engaged in advocacy work

    Della sopraproduzione : studio di economia sociale / F. Wiede

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    Della sopraproduzione : studio di economia sociale / F. Wiede Milano : Bignami e C., 1880 45 p. ; 19 cm

    Productie van zoutwateralgen voor toepassingen in food (en feed) deelrapport I : Werkpakketten 1&2 van project Foodgrade productie van zoutwateralgen: deelrapport I: Achtergrondinformatie zoutwateralgen: selectie van soorten en omgevingsomstandigheden

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    The commercial production of microalgae for food applications has been the focus of much attention lately. Culturing marine microalgae in reactors with LED lamps has several advantages. Marine algae contain valuable components such as antioxidants, which are described in this report, and high salinities in production systems can lead to less contamination. By producing them in closed systems at different LED light wavelengths (colours) high biomass concentrations can be obtained and production of biomass and valuable components can be increased. This report summarizes interesting components (i.e. pigments, lipids, carbohydrates) from marine microalgae in addition to general effects of light, nutrients, salt, pressure and mutations on algae growth. The influence of several parameters on biomass growth and pigment formation of several commercially interesting marine algae species is described. These parameters include light intensity, wavelength, light path length, nitrogen source and concentration, mutagens, dilution/refreshment rates, mixing conditions, temperature, salt concentration, flashing (alternating L/D cycles), mixotrophic/phototrophic conditions, alternative nutrient sources, mixed cultures and Si addition. Species that are described in detail include Dunaliella salina and tertiolecta, Arthrospira platensis, Nannochloropsis gaditana and sp., Phaeodactylum tricornutum, Porphyridium purpureum, Tetraselmis chuii, Odontella aurita and Odontella sinensis

    T-Cell Protein Tyrosine Phosphatase Attenuates STAT3 and Insulin Signaling in the Liver to Regulate Gluconeogenesis

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    OBJECTIVE: Insulin-induced phosphatidylinositol 3-kinase (PI3K)/Akt signaling and interleukin-6 (IL-6)-instigated JAK/STAT3-signaling pathways in the liver inhibit the expression of gluconeogenic genes to decrease hepatic glucose output. The insulin receptor (IR) and JAK1 tyrosine kinases and STAT3 can serve as direct substrates for the T-cell protein tyrosine phosphatase (TCPTP). Homozygous TCPTP-deficiency results in perinatal lethality prohibiting any informative assessment of TCPTP's role in glucose homeostasis. Here we have used Ptpn2+/- mice to investigate TCPTP's function in glucose homeostasis. RESEARCH DESIGN AND METHODS: We analyzed insulin sensitivity and gluconeogenesis in chow versus high-fat-fed (HFF) Ptpn2+/- and Ptpn2+/+ mice and insulin and IL-6 signaling and gluconeogenic gene expression in Ptpn2+/- and Ptpn2+/+ hepatocytes. RESULTS: HFF Ptpn2+/- mice exhibited lower fasted blood glucose and decreased hepatic glucose output as determined in hyperinsulinemic euglycemic clamps and by the decreased blood glucose levels in pyruvate tolerance tests. The reduced hepatic glucose output coincided with decreased expression of the gluconeogenic genes G6pc and Pck1 and enhanced hepatic STAT3 phosphorylation and PI3K/Akt signaling in the fasted state. Insulin-induced IR-beta-subunit Y1162/Y1163 phosphorylation and PI3K/Akt signaling and IL-6-induced STAT3 phosphorylation were also enhanced in isolated Ptpn2+/- hepatocytes. The increased insulin and IL-6 signaling resulted in enhanced suppression of G6pc and Pck1 mRNA. CONCLUSIONS: Liver TCPTP antagonises both insulin and STAT3 signaling pathways to regulate gluconeogenic gene expression and hepatic glucose output
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