1,222 research outputs found

    'Older people for older people' toolkit: developing social enterprise and service delivery in remote and rural areas

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    Developing flow in S-shaped ducts. 1: Square cross-section duct

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    Laser-Doppler velocimetry was used to measure the laminar and turbulent flow in an S-duct formed with two 22.5 deg sectors of a bend with ratio of mean radius of curvature to hydraulic diameter of 7.0. The boundary layers at the inlet to the bend were about 25% and 15% of the hydraulic diameter for the laminar and turbulent flows, respectively. Pressure-driven secondary flows develop in the first half of the S-duct and persist into the second half but are largely reversed by the exit plane as a consequence of the change in the sense of curvature. There is, however, a region near the outer wall of the second bend where the redistribution of the streamwise isotachs results in a reinforcement of the secondary flow which was established in the first half of the S-duct. The net redistribution of the streamwise isotachs is comparable to that occurring in unidirectional bends of stronger curvature. The wall pressure distribution was also measured for the turbulent flow and quantifies the expected large variations in the longitudinal pressure gradient distributions which occur at different radial locations

    Qualitative website analysis of information on birth after caesarean section

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    Date of Acceptance: 10/08/2015 © 2015 Peddie et al.Peer reviewedPublisher PD

    The development and evaluation of 3-dimensional models of cold flow in internal combustion engines

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    Scaling of Hunter Gatherer Camp Size and Human Sociality

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    One of the most commonly-observed properties of human settlements, both past and present, is the tendency for larger settlements to display higher population densities. Work in urban science and archaeology suggests this densification pattern reflects an emergent spatial equilibrium where individuals balance movement costs with social interaction benefits, leading to increases in aggregate productivity and social interdependence. In this context, it is perhaps not surprising that the more temporary camps created by mobile hunters and gatherers exhibit a tendency to become less dense with their population size. Here we examine why this difference occurs and consider conditions under which hunter-gatherer groups may transition to sedentism and densification. We investigate the relationship between population and area in mobile hunter-gatherer camps using a dataset, representing a large cross-cultural sample, derived from the ethnographic literature. We present a model based on the interplay between social interactions and scalar stress for the relationship between camp area and group size that describes the observed patterns among mobile hunter-gatherers. The model highlights the tradeoffs between the costs and benefits of proximity and interaction that are common to all human aggregations and specifies the constraints that must be overcome for economies of scale and cooperation to emerge

    An Approach to Web-Scale Named-Entity Disambiguation

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    We present a multi-pass clustering approach to large scale. wide-scope named-entity disambiguation (NED) oil collections of web pages. Our approach Uses name co-occurrence information to cluster and hence disambiguate entities. and is designed to handle NED on the entire web. We show that on web collections, NED becomes increasing), difficult as the corpus size increases, not only because of the challenge of scaling the NED algorithm, but also because new and surprising facets of entities become visible in the data. This effect limits the potential benefits for data-driven approaches of processing larger data-sets, and suggests that efficient clustering-based disambiguation methods for the web will require extracting more specialized information front documents

    Lack of Restoration in Vivo by K+-Channel Modulators of Jejunal Fluid Absorption after Heat Stable Escherichia coli Enterotoxin (STa) Challenge

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    Enhanced potassium ion permeability at the enterocyte basolateral membrane is assumed to facilitate sustained chloride ion and fluid secretion into the intestinal lumen during episodes of secretory diarrhoeal disease. To examine this concept in vivo, two potassium ion channel blockers and a channel opener were coperfused with E. coli heat stable STa enterotoxin to determine whether such compounds improved or worsened the inhibited fluid absorption. In the STa (80 ng/mL) challenged jejunal loop, the fluid absorption rate of 28.6 ± 5.8 (14) μL/cm/hr was significantly below (P < .001) the normal rate of 98.8 ± 6.2 (17) μL/cm/hr. Intraluminal (300 uM) glibenclamide added to STa perfused loops failed to improve the inhibited fluid absorption rate, which was 7.4 ± 3.2 (6) μL/cm/hr on coperfusion with STa. Similarly, on coperfusion with 30 uM clotrimazole, the fluid absorption rate with STa present remained inhibited at 11.4 ± 7.0 (4) μL/cm/hr. On coperfusion with intraluminal 1 uM cromakalim, STa reduced fluid absorption significantly (P < .02) to 24.7 ± 8.0 (10) μL/cm/hr, no different from STa challenge in the absence of cromakalim. Infusion i.v. with these agents also failed to restore fluid absorption after STa challenge. These observations do not support the proposed potassium ion permeability event as a necessary corollary of enterotoxin-mediated secretion. This makes it unlikely that modulators of such permeability prevent enterocyte secretion in diarrhoeal disease
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