322 research outputs found

    A Study of the Effect of a Child\u27s Physical Attractiveness upon Verbal Scoring of the Wechsler Intelligence Scale for Children (Revised) and upon Personality Attributions

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    The purpose of this research was to investigate possible examiner bias in scoring the Verbal subtests of the Wechsler Intelligence Scale for Children (Revised) due to the level of facial attractiveness of the child. Sex of the child and sex of the research subject were also included as independent variables. No main effect for attractiveness or sex x attractiveness interactions were found. Thus, little evidence emerged to suggest attractiveness stereotyping effects in an intelligence testing context. However, female children received significantly higher Comprehension and total Verbal scores than did male children. In addition, while male subjects did not provide differential Verbal scores for male and female children, female subjects tended to be biased toward female children, regardless of attractiveness level. A secondary goal of this study was to determine if the research subjects differentially attributed positive characteristics to attractive versus unattractive children. Indeed, it was empirically established that, in this testing environment, adults attributed more positive personality and social characteristics to attractive than unattractive children. Implications for clinicians/diagnosticians are discussed. It is suggested that future research attempt to delineate a continuum of diagnostic measures wherein one pole represents objective measures with little risk of bias and the other pole is the extreme of subjective instruments with high resk of examiner bias

    Evaluating Accessibility Issues in Urbana to Improve Safety at an Intersection

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    Details the efforts of the author to advocate for a safer pedestrian crossing at the intersection of Philo Road and Florida Avenue in Urbana, Illinois, especially for those in the community with disabilities

    Diseño del plan de marketing para la Empresa Preparación Física Integral Wheeler ubicada en la ciudad de Pereira

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    Este trabajo contiene la investigación necesaria para la realización de un plan estratégico de marketing para la empresa Centro de entrenamiento Wheeler, partiendo de un análisis de la situación actual, a través del cual se realiza un diagnóstico de su estructura organizacional; se identifican las oportunidades, fortalezas, amenazas y debilidades y se analiza la mezcla de marketing actual. Igualmente, se desarrollan diferentes instrumentos para analizar la competencia y segmentar el mercado para caracterizar el consumidor, permitiendo definir el producto en estudio Fitness. Finalmente se plantean estrategias en cuanto a Producto, Precio, Plaza y Promoción; se construye el plan estratégico de marketing estableciendo las acciones tácticas necesarias para llevar a cabo cada actividad; así mismo se plantea el presupuesto, cronograma y métodos de control, herramientas que orientaran a la organización en la correcta realización de este plan

    Modeling and environmental implications of methanol production from biogenic CO2in the sugarcane industry

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    This article presents a comprehensive model for the industrial production of methanol through the direct hydrogenation of biogenic CO2 from a biorefinery. Carbon capture and transformation to methanol are modeled through process simulation, ensuring that the H2 used for CO2 reduction, as well as electrical power requirements, are renewable. The environmental assessment is performed via a cradle-to-gate life cycle assessment study. The approach is applied to a typical large-scale sugar-ethanol complex in Argentina. The results show that the production of green methanol is a good option for the decarbonization of the industry and the methanol market. The sustainability of the overall process largely depends on the sustainability of the agricultural tasks that form the basis of the biorefinery. This is an unavoidable aspect that is not taken into account in many environmental studies on the production of CO2-based products, which leave aside the origin of the CO2.Fil: Cuezzo, Ana María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Departamento de Ingeniería en Procesos y Gestión Industrial; ArgentinaFil: Araujo, Paula Zulema. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Departamento de Ingeniería en Procesos y Gestión Industrial; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Wheeler, Jonathan. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Departamento de Ingeniería en Procesos y Gestión Industrial; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Mele, Fernando Daniel. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Departamento de Ingeniería en Procesos y Gestión Industrial; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

    Functional analysis of Girardia tigrina transcriptome seeds pipeline for anthelmintic target discovery

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    Background Neglected diseases caused by helminth infections impose a massive hindrance to progress in the developing world. While basic research on parasitic flatworms (platyhelminths) continues to expand, researchers have yet to broadly adopt a free-living model to complement the study of these important parasites. Methods We report the high-coverage sequencing (RNA-Seq) and assembly of the transcriptome of the planarian Girardia tigrina across a set of dynamic conditions. The assembly was annotated and extensive orthology analysis was used to seed a pipeline for the rational prioritization and validation of putative anthelmintic targets. A small number of targets conserved between parasitic and free-living flatworms were comparatively interrogated. Results 240 million paired-end reads were assembled de novo to produce a strictly filtered predicted proteome consisting of over 22,000 proteins. Gene Ontology annotations were extended to 16,467 proteins. 2,693 sequences were identified in orthology groups spanning flukes, tapeworms and planaria, with 441 highlighted as belonging to druggable protein families. Chemical inhibitors were used on three targets in pharmacological screens using both planaria and schistosomula, revealing distinct motility phenotypes that were shown to correlate with planarian RNAi phenotypes. Conclusions This work provides the first comprehensive and annotated sequence resource for the model planarian G. tigrina, alongside a prioritized list of candidate drug targets conserved among parasitic and free-living flatworms. As proof of principle, we show that a simple RNAi and pharmacology pipeline in the more convenient planarian model system can inform parasite biology and serve as an efficient screening tool for the identification of lucrative anthelmintic targets

    Au+Au central collisions at 150, 250 and 400 AMeV energies in QMD with relativistic forces

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    An extensive comparison of the recent experimental data published by the FOPI collaboration at GSI with the results of a relativistically covariant formulation of a QMD code is presented. For most of the quantities we find agreement with the experimental results showing that the derived force has a reasonable momentum dependence.Comment: 33 pages with 18 EPSF figures included. Final version to appear in Nucl. Phys.

    The elephant in the room?:Why spatial stigma does not receive the public health attention it deserves

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    In the context of health inequalities, spatial stigma refers to the ways that areas experiencing socioeconomic inequalities become negatively portrayed and labelled in public, official and policy discourses. With respect to the body of research on social determinants of health and health inequalities, and attention accorded to this issue in policy or practice, spatial stigma remains significantly under-represented compared with other possible causal factors. We suggest three explanations contributing to this neglect. First, the lack of research into spatial stigma originates from a more limited public health focus on the symbolic meanings of places for health, compared to their physical and social dimensions. Second, lay involvement and evidence of lived experiences of health inequalities continues to be under-represented in public health decision-making. Finally, it is the case that public health organizations may also be contributing to negative area portrayals in their communications of health inequalities. There are growing examples of social action being taken by groups of residents to resist this stigma through the promotion of more positive portrayals of areas and communities. Greater public health attention to this issue as well is likely to result in health gains and aid the development of more effective health inequalities strategies

    Proteomic Approach to Evaluate Mechanisms That Contribute to Food Allergenicity: Comparative 2D-DIGE Analysis of Radioallergosorbent Test Positive and Negative Patients

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    Proteomic profiles of RAST+ subjects with severe food allergies and RAST− subjects were compared using 2D-DIGE analysis to obtain candidate biomarkers specific to food allergies. Our analysis highlighted 52 proteins that were differentially expressed between the RAST+ and RAST− groups of which 37 were successfully identified that include chondroitin sulfates, zinc finger proteins, C-type lectins, retinoic acid binding proteins, heat shock proteins, myosin, cytokines, mast cell expressed proteins, and MAP kinases. Biological network analysis tool Metacore revealed that most of these regulated proteins play a role in immune tolerance, hypersensitivity and modulate cytokine patterns inducing a Th2 response that typically results in IgE-mediated allergic response which has a direct or indirect biological link to food allergy. Identifying unique biomarkers associated with certain allergic phenotypes and potentially cross-reactive proteins through bioinformatics analyses will provide enormous insight into the mechanisms that underlie allergic response in patients with food allergies
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