Effects of halothane and isoflurane anaesthesia on microcirculatory blood flow in musculocutaneous flaps

Hypoperfusion and necrosis in musculocutaneous flaps used for reconstruction of tissue defects is still a significant clinical problem. Although the causes of hypoperfusion are frequently surgical in nature, little is known about the effects of anaesthetic management on blood flow in flaps or the outcome of flap surgery. We compared in minipigs the effects of halothane and isoflurane anaesthesia in equipotent doses on microcirculatory blood flow (MBF) in the skin and muscle part of musculocutaneous flaps and also in intact (control) skin and muscle. Measurements were made during stable normovolaemic conditions and during mild to moderate hypovolaemia (withdrawal of 5%, 10% and 15% of total blood volume). Multi-channel laser Doppler flowmetry (LDF) was used to measure MBF and electromagnetic flowmetry (EMF) for total flap blood flow. During normovolaemic conditions there was no significant difference between the two groups in central haemodynamic or respiratory data. After 15% blood loss, however, there was a significant decrease in mean arterial pressure and cardiac output in the halothane group while there was no significant change in the isoflurane group (P < 0.05). MBF in control skin, control muscle and flap muscle remained approximately 10−15% higher in the isoflurane than in the halothane group throughout the study. In the isoflurane group, MBF in flap skin was unchanged during normovolaemia and there was less than 10% decrease during hypovolaemia. In the halothane group hypovolaemia caused a significant decrease in MBF in flap skin: 27% decrease after 5% blood loss, 45% decrease after 10% blood loss and 49% decrease after 15% blood loss compared with 5%, 20% and 21%, respectively, in intact skin. We conclude that during normovolaemic conditions MBF was well maintained in musculocutaneous flaps in minipigs both with halothane and isoflurane anaesthesia; however, during mild to moderate hypovolemia MBF decreased markedly in flap skin with halothane anaesthesia while it remained unchanged with isofluran

An XMM-Newton observation of the nova-like variable UX UMa: spatially and spectrally resolved two-component X-ray emission

In the optical and ultraviolet regions of the electromagnetic spectrum, UX Ursae Majoris is a deeply eclipsing cataclysmic variable. However, no soft X-ray eclipse was detected in ROSAT observations. We have obtained a 38 ksec XMM-Newton observation to further constrain the origin of the X-rays. The combination of spectral and timing information allows us to identify two components in the X-ray emission of the system. The soft component, dominant below photon energies of 2 keV, can be fitted with a multi-temperature plasma model and is uneclipsed. The hard component, dominant above 3 keV, can be fitted with a kT ~ 5 keV plasma model and appears to be deeply eclipsed. We suggest that the most likely source of the hard X-ray emission in UX UMa, and other systems in high mass transfer states, is the boundary layer.Comment: To appear in MNRAS Letter

Spin-Charge Separation in Two Dimensions - A Numerical Study

The question of spin-charge separation in two-dimensional lattices has been addressed by numerical simulations of the motion of one hole in a half-filled band. The calculations have been performed on finite clusters with Hubbard and t-J models. By comparing the time evolution of spin and charge polarisation currents in one and two dimensions, evidence in favor of spin-charge separation in two dimensions is presented. In contrast with this, spin-charge separation is absent in a highly doped, metallic, system.Comment: RevTeX 3.0, 10 Pages, 6 PostScript Figures (on request

Particle detection experiment for Applications Technology Satellite 1 /ATS-1/ Final report

Applications technology satellite particle detection experiment for measuring energy spectra of earth magnetic fiel

Symbolic Manipulators Affect Mathematical Mindsets

Symbolic calculators like Mathematica are becoming more commonplace among upper level physics students. The presence of such a powerful calculator can couple strongly to the type of mathematical reasoning students employ. It does not merely offer a convenient way to perform the computations students would have otherwise wanted to do by hand. This paper presents examples from the work of upper level physics majors where Mathematica plays an active role in focusing and sustaining their thought around calculation. These students still engage in powerful mathematical reasoning while they calculate but struggle because of the narrowed breadth of their thinking. Their reasoning is drawn into local attractors where they look to calculation schemes to resolve questions instead of, for example, mapping the mathematics to the physical system at hand. We model the influence of Mathematica as an integral part of the constant feedback that occurs in how students frame, and hence focus, their work

Thermodynamically consistent equilibrium properties of normal-liquid Helium-3

The high-precision data for the specific heat C_{V}(T,V) of normal-liquid Helium-3 obtained by Greywall, taken together with the molar volume V(T_0,P) at one temperature T_0, are shown to contain the complete thermodynamic information about this phase in zero magnetic field. This enables us to calculate the T and P dependence of all equilibrium properties of normal-liquid Helium-3 in a thermodynamically consistent way for a wide range of parameters. The results for the entropy S(T,P), specific heat at constant pressure C_P(T,P), molar volume V(T,P), compressibility kappa(T,P), and thermal expansion coefficient alpha(T,P) are collected in the form of figures and tables. This provides the first complete set of thermodynamically consistent values of the equilibrium quantities of normal-liquid Helium-3. We find, for example, that alpha(T,P) has a surprisingly intricate pressure dependence at low temperatures, and that the curves alpha(T,P) vs T do not cross at one single temperature for all pressures, in contrast to the curves presented in the comprehensive survey of helium by Wilks. Corrected in cond-mat/9906222v3: The sign of the coefficient d_0 was misprinted in Table I of cond-mat/9906222v1 and v2. It now correctly reads d_0=-7.1613436. All results in the paper were obtained with the correct value of d_0. (We would like to thank for E. Collin, H. Godfrin, and Y. Bunkov for finding this misprint.)Comment: 19 pages, 19 figures, 9 tables; published version; note added in proof; v3: misprint correcte

Combination Rules, Charge Symmetry, and Hall Effect in Cuprates

The rule relating the observed Hall coefficient to the spin and charge responses of the uniform doped Mott insulator is derived. It is essential to include the contribution of holon and spinon three-current correlations to the effective action of the gauge field. In the vicinity of the Mott insulating point the Hall coefficient is holon dominated and weakly temperature dependent. In the vicinity of a point of charge conjugation symmetry the holon contribution to the observed Hall coefficient is small: the Hall coefficient follows the temperature dependence of the diamagnetic susceptibility with a sign determined by the Fermi surface shape. NOTE: document prepared using REVTEX. (3 Figs, not included, available on request from: [email protected])Comment: 8 page

g-on Mean Field Theory of the t-J Model

Implication of our recent proposal [J. Phys. Soc. Jpn. 65 (1996) 687] to treat large-amplitude gauge-field fluctuations around the slave-boson mean-field theory for the t-J model has been explored in detail. By attaching gauge flux to spinons and holons and then treating them as free g-on's which respect the time-reversal symmetry, the optimum exclusion (g) and exchange (\a) statistics have been determined in the plane of doping rate and temperature. Two different relations between \a and g have been investigated, namely g=|\a| (Case1) and g=|\a|(2-|\a|) (Case2). The results indicate that slave fermion is favored at low doping while slave boson at high doping. For two dimension, in Case1 intermediate statistics are found in between, while in Case2 no intermediate statistics are found. The consequences of varying the dimensionality and strength of J have been studied also. The latter has no qualitative effect for both cases, while the former has a profound effect in Case1.Comment: 18 pages, 11 figures two of them are figure 8; submitted to Phys. Rev. B; notes and citations are added, as seen in page 17; E-mails: [email protected], [email protected]

Effect of Iodine Doping on Bi2_{2}Sr2_{2}Ca1_{1}Cu2_{2}Ox_{x}: Charge Transfer or Interlayer Coupling?

A comparative study has been made of iodine-intercalated Bi$_{2}$Sr$_{2}$Ca$_{1}$Cu$_{2}$O$_{x}$ single crystal and 1 atm O$_{2}$ annealed Bi$_{2}$Sr$_{2}$Ca$_{1}$Cu$_{1}$O$_{x}$ single crystal using AC susceptibility measurement, X-ray photoemission (XPS) and angle-resolved ultraviolet photoemission spectroscopy (ARUPS). AC susceptibility measurement indicates that O$_{2}$-doped samples studied have T$_{c}$ of 84 $^{o}$K, whereas T$_{c}$ of Iodine-doped samples studied are 80 $^{o}$K. XPS Cu 2p core level data establish that the hole concentration in the CuO$_{2}$ planes are essentially the same for these two kinds of samples. ARUPS measurements show that electronic structure of the normal states near the Fermi level has been strongly affected by iodine intercalation. We conclude that the dominant effect of iodine doping is to alter the interlayer coupling.Comment: LBL 9 pages, APS_Revtex. 5 Figures, available upon request. UW-Madison preprin

Persistent spin and mass currents and Aharonov-Casher effect

Spin-orbit interaction produces persistent spin and mass currents in the ring via the Aharonov-Casher effect. The experiment in $^3He-A_1$ phase, in which this effect leads to the excitation of mass and spin supercurrent is proposed.Comment: 10 page