494 research outputs found

    Acceleration of Diffusional Jumps of Interstitial Fe with Increasing Ge Concentration in Si1 − x Ge x Alloys Observed by Mössbauer Spectroscopy

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    Radioactive 57Mn isotopes have been implanted into Si1 − x Ge x crystals (x ≤ 0.1) at elevated temperatures for Mössbauer studies of the diffusion of interstitial 57Fe daughter atoms. The atomic jump frequency is found to increase upon Ge alloying. This is attributed to a lowering of the activation energy, i.e. the saddle point energy at hexagonal interstitial sites with Ge neighbour atom

    Spin half fermions with mass dimension one: theory, phenomenology, and dark matter

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    We provide the first details on the unexpected theoretical discovery of a spin-one-half matter field with mass dimension one. It is based upon a complete set of dual-helicity eigenspinors of the charge conjugation operator. Due to its unusual properties with respect to charge conjugation and parity, it belongs to a non-standard Wigner class. Consequently, the theory exhibits non-locality with (CPT)^2 = - I. We briefly discuss its relevance to the cosmological `horizon problem'. Because the introduced fermionic field is endowed with mass dimension one, it can carry a quartic self-interaction. Its dominant interaction with known forms of matter is via Higgs, and with gravity. This aspect leads us to contemplate the new fermion as a prime dark matter candidate. Taking this suggestion seriously we study a supernova-like explosion of a galactic-mass dark matter cloud to set limits on the mass of the new particle and present a calculation on relic abundance to constrain the relevant cross-section. The analysis favours light mass (roughly 20 MeV) and relevant cross-section of about 2 pb. Similarities and differences with the WIMP and mirror matter proposals for dark matter are enumerated. In a critique of the theory we bare a hint on non-commutative aspects of spacetime, and energy-momentum space.Comment: 78 pages [Changes: referee-suggested improvements, additional important references, and better readability

    Hints of (trans-Planckian) asymptotic freedom in semiclassical cosmology

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    We employ the semiclassical approximation to the Wheeler-DeWitt equation in the spatially flat de Sitter Universe to investigate the dynamics of a minimally coupled scalar field near the Planck scale. We find that, contrary to naive intuition, the effects of quantum gravitational fluctuations become negligible and the scalar field states asymptotically approach plane-waves at very early times. These states can then be used as initial conditions for the quantum states of matter to show that each mode essentially originated in the minimum energy vacuum. Although the full quantum dynamics cannot be solved exactly for the case at hand, our results can be considered as supporting the general idea of asymptotic safety in quantum gravity.Comment: 11 pages, 2 figures; replaced to match content of published versio

    Rabies mortality and morbidity associated with animal bites in Africa: a case for integrated rabies disease surveillance, prevention and control: a scoping review

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    OBJECTIVE: The objective of this scoping review was to map the current situation and available evidence and gaps on rabies morbidity, mortality, integrated rabies surveillance programmes, and existing prevention and control strategies in Africa. METHODS: We conducted a systematic scoping review following the Joanna Briggs methodology and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews checklist. Medline, Embase, CINAHL (EBSCOHost), Scopus, Web of Science and rabies web conferences were used to search for peer-reviewed publications between January 1946 and May 2020. Two researchers reviewed the studies and extracted data based on author (year) and region, study design and data collection duration, participants/comparators, interventions, control conditions/exposures and outcomes (rabies mortality and morbidity) and key findings/gaps/challenges. The results were reported narratively using Arksey and O'Malley's methodological framework. RESULTS: Electronic search yielded 2775 records, of which 43 studies were included. A total of 543 714 bite victims were censored through the included studies. Most of the victims were less than 15 years of age. The studies included rabies morbidity (21) and mortality (15) fluctuating in space and time across Africa depending on countries' rabies prevention and control practices (16). Others were surveillance (nine studies); surveillance and prevention (five studies); management and control (seven studies); and surveillance, prevention and control (six studies). We found challenges in rabies reporting, existing dog vaccination programmes and post-exposure prophylaxis availability or compliance. CONCLUSION: This study found challenges for dog rabies control and elimination in Africa and the need for a policy to drive the goal of zero dog-transmitted rabies to humans by 2030.This is an open-access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build on this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated and the use is non-commercial (see http://creativecommons.org/licenses/by-nc/4.0/)

    Casimir effect: running Newton constant or cosmological term

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    We argue that the instability of Euclidean Einstein gravity is an indication that the vacuum is non perturbative and contains a condensate of the metric tensor in a manner reminiscent of Yang-Mills theories. As a simple step toward the characterization of such a vacuum the value of the one-loop effective action is computed for Euclidean de Sitter spaces as a function of the curvature when the unstable conformal modes are held fixed. Two phases are found, one where the curvature is large and gravitons should be confined and another one which appears to be weakly coupled and tends to be flat. The induced cosmological constant is positive or negative in the strongly or weakly curved phase, respectively. The relevance of the Casimir effect in understanding the UV sensitivity of gravity is pointed out.Comment: Final, slightly extended version, to appear in Classical and Quantum Gravit

    Quantifying the improvement of surrogate indices of hepatic insulin resistance using complex measurement techniques

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    We evaluated the ability of simple and complex surrogate-indices to identify individuals from an overweight/obese cohort with hepatic insulin-resistance (HEP-IR). Five indices, one previously defined and four newly generated through step-wise linear regression, were created against a single-cohort sample of 77 extensively characterised participants with the metabolic syndrome (age 55.6±1.0 years, BMI 31.5±0.4 kg/m2; 30 males). HEP-IR was defined by measuring endogenous-glucose-production (EGP) with [6–62H2] glucose during fasting and euglycemic-hyperinsulinemic clamps and expressed as EGP*fasting plasma insulin. Complex measures were incorporated into the model, including various non-standard biomarkers and the measurement of body-fat distribution and liver-fat, to further improve the predictive capability of the index. Validation was performed against a data set of the same subjects after an isoenergetic dietary intervention (4 arms, diets varying in protein and fiber content versus control). All five indices produced comparable prediction of HEP-IR, explaining 39–56% of the variance, depending on regression variable combination. The validation of the regression equations showed little variation between the different proposed indices (r2 = 27–32%) on a matched dataset. New complex indices encompassing advanced measurement techniques offered an improved correlation (r = 0.75, P<0.001). However, when validated against the alternative dataset all indices performed comparably with the standard homeostasis model assessment for insulin resistance (HOMA-IR) (r = 0.54, P<0.001). Thus, simple estimates of HEP-IR performed comparable to more complex indices and could be an efficient and cost effective approach in large epidemiological investigations

    Strategic responses to global challenges: The case of European banking, 1973–2000

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    In applying a strategy, structure, ownership and performance (SSOP) framework to three major clearing banks (ABN AMRO, UBS, Barclays), this article debates whether the conclusions generated by Whittington and Mayer about European manufacturing industry can be applied to the financial services sector. While European integration plays a key role in determining strategy, it is clear that global factors were far more important in determining management actions, leading to significant differences in structural adaptation. The article also debates whether this has led to improved performance, given the problems experienced with both geographical dispersion and diversification, bringing into question the quality of decision-making over the long term

    A new measurement of the properties of the rare decay K -> pi+ e+ e-

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    A large low-background sample of events (10300) has been collected for the rare decay of kaons in flight K+ -> pi+ e+ e- by experiment E865 at the Brookhaven AGS. The decay products were accepted by a broad band high-resolution charged particle spectrometer with particle identification. The branching ratio (2.94 +- 0.05(stat.) +- 0.13(syst.) +- 0.05(model))*10**{-7} was determined normalizing to events from the decay chain K+ -> pi+ pi0; pi0 -> e+ e- gamma. From the analysis of the decay distributions the vector nature of this decay is firmly established now, and limits on scalar and tensor contributions are deduced. From the (e+ e-) invariant mass distribution the decay form factor f(z)=f0(1+ delta*z) (z=M(ee)**2/m(K)**2) is determined with delta=2.14 +- 0.13 +- 0.15. Chiral QCD perturbation theory predictions for the form factor are also tested, and terms beyond leading order O(p**4) are found to be important.Comment: 4 pages, 5 figure

    Renormalization group improved gravitational actions: a Brans-Dicke approach

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    A new framework for exploiting information about the renormalization group (RG) behavior of gravity in a dynamical context is discussed. The Einstein-Hilbert action is RG-improved by replacing Newton's constant and the cosmological constant by scalar functions in the corresponding Lagrangian density. The position dependence of GG and Λ\Lambda is governed by a RG equation together with an appropriate identification of RG scales with points in spacetime. The dynamics of the fields GG and Λ\Lambda does not admit a Lagrangian description in general. Within the Lagrangian formalism for the gravitational field they have the status of externally prescribed ``background'' fields. The metric satisfies an effective Einstein equation similar to that of Brans-Dicke theory. Its consistency imposes severe constraints on allowed backgrounds. In the new RG-framework, GG and Λ\Lambda carry energy and momentum. It is tested in the setting of homogeneous-isotropic cosmology and is compared to alternative approaches where the fields GG and Λ\Lambda do not carry gravitating 4-momentum. The fixed point regime of the underlying RG flow is studied in detail.Comment: LaTeX, 72 pages, no figure
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