2,782 research outputs found

    Historical Calibration of a Water Account System

    Get PDF
    Models that are used for future based scenarios should be calibrated with historical water supply and use data. Historical water records in Australia are discontinuous, incomplete and often incongruently disaggregated. We present a systematic method to produce a coherent reconstruction of the historical provision and consumption of water in Victorian catchments. This is demonstrated using WAS: an accounting and simulation tool that tracks the stocks and flows of physical quantities relating to the water system. The WAS is also part of, and informed by, an integrated framework of stocks and flows calculators for simulating long-term interactions between other sectors of the physical economy. Both the WAS and related frameworks consider a wide scope of inputs regarding population, land use, energy and water. The physical history of the water sector is reconstructed by integrating water data with these information sources using a data modelling process that resolves conflicts and deduces missing information. The WAS allows strategic exploration of water and energy implications of scenarios of water sourcing, treatment, delivery and end use cognisant of historical records.water accounting, stocks and flows, historical time series, data modelling, calibration

    An intensity-expansion method to treat non-stationary time series: an application to the distance between prime numbers

    Full text link
    We study the fractal properties of the distances between consecutive primes. The distance sequence is found to be well described by a non-stationary exponential probability distribution. We propose an intensity-expansion method to treat this non-stationarity and we find that the statistics underlying the distance between consecutive primes is Gaussian and that, by transforming the distance sequence into a stationary one, the range of Gaussian randomness of the sequence increases.Comment: 11 pages, 7 figures, in press on 'Chaos, Solitons & Fractals

    Mirroring Jesus’s Prayerful Approach to Interactions with Dissatisfied Followers through the Lens of the Modern Worship Pastor

    Get PDF
    This study shows the life and mission of Jesus through His interactions with conflict and will show how worship pastors can apply these lessons to the church. Detailing Jesus\u27s prayer life and His approach to interacting with others, examining the approach worship leaders should have when interacting with similar people. The report will concentrate on three areas of study, including Jesus\u27s prayer life, his ministry, and how the worship pastor can create a church that parallels Christ. Jesus\u27 ministry and discussions with the Pharisees show worship pastors how they should approach church members. This discussion is due to the struggles with ministry and how worship pastors face difficult situations, like Jesus\u27s ministry. The research finds themes of love, compassion, service, and mercy that a servant leader needs to process. These qualities are essential for a meaningful worship pastor to overcome adversity. Worship leaders need to study the life of Jesus when dealing with the church Pharisees and develop regard, care, and benevolence for people. When observing and mirroring the heart of Jesus, the worship pastor can become a strong influence. This research will study Jesus\u27s interactions and give application to the worship pastor\u27s ministry

    Approximate g-functions for selection of borehole field configurations used with ground-source heat pump systems

    Get PDF
    The arrangement of boreholes in ground heat exchangers used with ground-source heat pump systems is commonly based on pre-computed libraries of g-functions with standard configurations, e.g. placing the boreholes on a uniformly-spaced rectangular grid. Particularly for larger fields with many boreholes in situations with significant annual heat rejection/extraction imbalance, these configurations may be far from optimal. That is, depending on the space constraints, it may be possible to reduce the number of boreholes and amount of drilling required by shifting the positions of the boreholes to make better use of the available space. These configurations of boreholes are unlikely to be found in any library. Furthermore, manual arrangement of boreholes in complex-shaped fields is tedious and time-consuming for the engineer. Therefore, tools are needed that can automatically arrange boreholes in candidate configurations to fit the available land area, calculate the g-function for these configurations, select the best configuration, and determine the required depth for the best configuration. These tools need to be reasonably fast in order to be practical for the design engineer. This paper reports on a fast method for calculating approximate g-functions using non-uniform segments and pre-computed integral tables. Despite being “approximate” g-functions, the difference between a g-function calculated with a more detailed method and the approximate g-function is usually under 1% RMSE. The g-functions for borehole fields with 300, 500, and 1000 boreholes can be calculated in about 2, 6, and 30 seconds on a run-of-the-mill desktop PC. The paper presents the methodology, quantifies the computational time requirements and accuracy of both the g-function and the resulting designs.Mechanical and Aerospace Engineerin

    The epidemiology of irritable bowel syndrome

    Get PDF
    Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using clinical criteria. This paper discusses the nature of the diagnostic process for IBS and how this impacts epidemiological measurements. Depending on the diagnostic criteria employed, IBS affects around 11% of the population globally. Around 30% of people who experience the symptoms of IBS will consult physicians for their IBS symptoms. These people do not have significantly different abdominal symptoms to those who do not consult, but they do have greater levels of anxiety and lower quality of life. Internationally, there is a female predominance in the prevalence of IBS. There is 25% less IBS diagnosed in those over 50 years and there is no association with socioeconomic status. IBS aggregates within families and the genetic and sociological factors potentially underlying this are reviewed. Patients diagnosed with IBS are highly likely to have other functional disease and have more surgery than the general population. There is no evidence that IBS is associated with an increased mortality risk. The epidemiological evidence surrounding these aspects of the natural history is discussed

    An expert-systems approach to automatically determining flaw depth within CANDU pressure tubes

    Get PDF
    Delayed Hydride Cracking (DHC) is a crack growth mechanism that occurs in zirconium alloys, including the pressure tubes of CANDU reactors. DHC is caused by hydrogen in solution in zirconium components being diffused to any flaws present, resulting in an increased concentration of hydrogen within these flaws. An increased hydrogen concentration can lead to brittleness, followed by cracking, in high-stress regions of a pressure tube. Regular in-service ultrasonic inspection of CANDU pressure tubes aim to locate and classify any flaws that pose a potential for DHC initiation. A common approach to inspection is the use of a bespoke tool containing multiple ultrasonic transducers to ensure that each point on the pressure tube is inspected from a minimum of three angles during a scan. All flaws from within the inspected pressure tubes must be characterized prior to restarting the reactor, thus the time-consuming analysis process lies on the critical outage path. This process is manually intensive and often requires a significant amount of expert knowledge. A modular system to automatically process outage data to provide decision support to analysts has been developed. This system saves time on the critical outage path while providing repeatable and explicable measurements. Part of the analysis process requires the depth of all flaws to be measured, which is often the most time consuming stage of the analysis process. This paper describes an approach that utilizes captured analysts knowledge to perform automatic flaw depth estimation

    A comparison of the recording of comorbidity in primary and secondary care by using the Charlson Index to predict short-term and long-term survival in a routine linked data cohort

    Get PDF
    OBJECTIVE: Hospital admission records provide snapshots of clinical histories for a subset of the population admitted to hospital. In contrast, primary care records provide continuous clinical histories for complete populations, but might lack detail about inpatient stays. Therefore, combining primary and secondary care records should improve the ability of comorbidity scores to predict survival in population-based studies, and provide better adjustment for case-mix differences when assessing mortality outcomes. DESIGN: Cohort study. SETTING: English primary and secondary care 1 January 2005 to 1 January 2010. PARTICIPANTS: All patients 20 years and older registered to a primary care practice contributing to the linked Clinical Practice Research Datalink from England. OUTCOME: The performance of the Charlson index with mortality was compared when derived from either primary or secondary care data or both. This was assessed in relation to short-term and long-term survival, age, consultation rate, and specific acute and chronic diseases. RESULTS: 657,264 people were followed up from 1 January 2005. Although primary care recorded more comorbidity than secondary care, the resulting C statistics for the Charlson index remained similar: 0.86 and 0.87, respectively. Higher consultation rates and restricted age bands reduced the performance of the Charlson index, but the index's excellent performance persisted over longer follow-up; the C statistic was 0.87 over 1 year, and 0.85 over all 5 years of follow-up. The Charlson index derived from secondary care comorbidity had a greater effect than primary care comorbidity in reducing the association of upper gastrointestinal bleeding with mortality. However, they had a similar effect in reducing the association of diabetes with mortality. CONCLUSIONS: These findings support the use of the Charlson index from linked data and show that secondary care comorbidity coding performed at least as well as that derived from primary care in predicting survival

    A randomised controlled study of high intensity exercise as a dishabituating stimulus to improve hypoglycaemia awareness in people with type 1 diabetes:a proof of concept study

    Get PDF
    Aims/hypothesis Approximately 25% of people with type 1 diabetes have suppressed counterregulatory hormonal and symptomatic responses to insulin-induced hypoglycaemia, which renders them at increased risk of severe, disabling hypoglycaemia. This is called impaired awareness of hypoglycaemia (IAH), the cause of which is unknown. We recently proposed that IAH develops through habituation, a form of adaptive memory to preceding hypoglycaemia. Consistent with this hypothesis, we demonstrated restoration of defective counterregulatory hormonal responses to hypoglycaemia (referred to as dishabituation) in a rodent model of IAH following introduction of a novel stress stimulus (high intensity training [HIT]). In this proof-of-concept study we sought to further test this hypothesis by examining whether a single episode of HIT would amplify counterregulatory responses to subsequent hypoglycaemia in people with type 1 diabetes who had IAH (assessed by Gold score ≥4, modified Clarke score ≥4 or Dose Adjustment For Normal Eating (DAFNE) hypoglycaemia awareness rating 2 or 3). The primary outcome was the difference in adrenaline response to hypoglycaemia following both a single episode of HIT and rest. Methods In this randomised, crossover study 12 participants aged between 18 and 55 years with type 1 diabetes for ≥5 years and an HbA1c < 75 mmol/mol (9%) were recruited. Individuals were randomised using computer generated block randomisation to start with one episode of HIT (4 × 30 s cycle sprints [2 min recovery] at 150% of maximum wattage achieved during V˙O2peak assessment) or rest (control). The following day they underwent a 90 min hyperinsulinaemic–hypoglycaemic clamp study at 2.5 mmol/l with measurement of hormonal counterregulatory response, symptom scores and cognitive testing (four-choice reaction time and digit symbol substitution test). Each intervention and subsequent clamp study was separated by at least 2 weeks. The participants and investigators were not blinded to the intervention or measurements during the study. The investigators were blinded to the primary outcome and blood analysis results. Results All participants (six male and six female, age 19–54 years, median [IQR] duration of type 1 diabetes 24.5 [17.3–29.0] years, mean [SEM] HbA1c 56 [3.67] mmol/mol; 7.3% [0.34%]) completed the study (both interventions and two clamps). In comparison with the rest study, a single episode of HIT led to a 29% increase in the adrenaline (epinephrine) response (mean [SEM]) (2286.5 [343.1] vs 2953.8 [384.9] pmol/l); a significant increase in total symptom scores (Edinburgh Hypoglycaemia Symptom Scale: 24.25 [2.960 vs 27.5 [3.9]; p < 0.05), and a significant prolongation of four-choice reaction time (591.8 [22.5] vs 659.9 [39.86] ms; p < 0.01] during equivalent hypoglycaemia induced the following day. Conclusions/interpretation These findings are consistent with the hypothesis that IAH develops in people with type 1 diabetes as a habituated response and that introduction of a novel stressor can restore, at least partially, the adapted counterregulatory hormonal, symptomatic and cognitive responses to hypoglycaemia.Output Status: Forthcoming/Available Onlin
    corecore