High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study

One view of sarcoidosis is that the term covers many different diseases. However, no classification framework exists for the future exploration of pathogenetic pathways, genetic or trigger predilections, patterns of lung function impairment, or treatment separations, or for the development of diagnostic algorithms or relevant outcome measures. We aimed to establish agreement on high-resolution CT (HRCT) phenotypic separations in sarcoidosis to anchor future CT research through a multinational two-round Delphi consensus process. Delphi participants included members of the Fleischner Society and the World Association of Sarcoidosis and other Granulomatous Disorders, as well as members' nominees. 146 individuals (98 chest physicians, 48 thoracic radiologists) from 28 countries took part, 144 of whom completed both Delphi rounds. After rating of 35 Delphi statements on a five-point Likert scale, consensus was achieved for 22 (63%) statements. There was 97% agreement on the existence of distinct HRCT phenotypes, with seven HRCT phenotypes that were categorised by participants as non-fibrotic or likely to be fibrotic. The international consensus reached in this Delphi exercise justifies the formulation of a CT classification as a basis for the possible definition of separate diseases. Further refinement of phenotypes with rapidly achievable CT studies is now needed to underpin the development of a formal classification of sarcoidosis

Going public? Re-thinking visibility, ethics and recognition through participatory research praxis

Recent work in human geography has articulated the principles of an emerging ‘participatory ethics’. Yet despite sustained critical examination of the participatory conditions under which geographical knowledge is produced, far less attention has addressed how a participatory ethics might unsettle the conventional ways such knowledge continues to be received, circulated, exchanged and mediated. As such, the uptake of visual methods in participatory research praxis has drawn a range of criticism for assuming visual outputs ‘tell their own stories’ and that publics might be straightforwardly engage with them. In response, this paper develops an argument for adopting an ethical stance that takes a more situated, processual account of the ways participants themselves might convene their own forms of public engagement, and manage their own conditions of becoming visible through the research process. To do so the concept of an ethics of recognition is developed, drawing attention to the inter- and intra-subjective relations that shape the public research encounter, and signalling ways that participants might navigate such conditions in pursuit of their intuitive desire to give an account of themselves to others. This ethical stance is then used to rethink questions of visibility and publicness through the conditions of reception, mediation and exchange that took place during the efforts of a London-based participatory research project to ‘go public’. Drawing in particular on the experiences of one of the project participants, we suggest how a processual and contingent understanding of public engagement informed by such an ethics of recognition might be anticipated, approached and enacted

Post-Processed Integrated Microsystems

Sandia is a multiprogram laboratory operated by Sandia Corporation