The nature of ZbZ_b states from a combined analysis of Υ(5S)→hb(mP)π+π−\Upsilon(5S)\rightarrow h_b(mP) \pi^+ \pi^- and Υ(5S)→B(∗)Bˉ(∗)π\Upsilon(5S)\rightarrow B^{(\ast)}\bar B^{(\ast)}\pi

With a combined analysis of data on $\Upsilon(5S)\rightarrow h_b(1P,2P)\pi^+\pi^-$ and $\Upsilon(5S)\rightarrow B^{(\ast)}\bar B^{(\ast)}\pi$ in an effective field theory approach, we determine resonance parameters of $Z_b$ states in two scenarios. In one scenario we assume that $Z_b$ states are pure molecular states, while in the other one we assume that $Z_b$ states contain compact components. We find that the present data favor that there should be some compact components inside $Z_b^{(\prime)}$ associated with the molecular components. By fitting the invariant mass spectra of $\Upsilon(5S)\rightarrow h_b(1P,2P)\pi^+\pi^-$ and $\Upsilon(5S)\rightarrow B^{(\ast)}\bar B^{\ast}\pi$, we determine that the probability of finding the compact components in $Z_b$ states may be as large as about $40\%$.Comment: Discussions added, version published in EPJ

Circulating Lysophosphatidylcholines in Early Pregnancy and Risk of Gestational Diabetes in Chinese Women.

ObjectivesThis study aimed to explore associations of lysophosphatidylcholines (LPCs) in early pregnancy with gestational diabetes mellitus (GDM), and whether LPCs mediated the associations of bile acids with GDM risk or had interactive effects with bile acids on GDM risk.DesignWe conducted a 1:1 nested case-control study (n = 486) from a large prospective pregnant women cohort in urban Tianjin, China. Blood samples were collected at their first antenatal care visit (median at 10th gestational week). LPCs were measured by liquid chromatography-tandem mass spectrometry analysis. Conditional binary logistic regression and restricted cubic spline analysis were used to identify cutoff points of these metabolites for GDM risk.ResultsOf the 6 detectable LPCs, LPC14:0 less than 0.24 nmol/mL, LPC15:0 at 0.45 nmol/mL or greater, and LPC18:0 at 18.00 nmol/mL or greater were independently associated with GDM risk. Adjustment for LPC18:0 slightly attenuated odds ratios (ORs) of deoxycholic acid (DCA, ≤ 0.36 nmol/mL) and glycoursodeoxycholic acid (GUDCA, ≤ 0.07 nmol/mL) for GDM, and the correlations of DCA and GUDCA with LPC18:0 were weak. However, the presence of DCA at 0.36 nmol/mL or less greatly amplified the adjusted OR of LPC18:0 at 18.00 nmol/mL or greater alone for GDM from 8.18 (2.51-26.7) up to 17.7 (6.64-47.1), with significant additive interaction. Similarly, the presence of GUDCA at 0.07 nmol/mL or less also greatly amplified the adjusted OR of LPC18:0 at 18.00 nmol/mL or greater alone for GDM from 17.2 (1.77-168) up to 73.8 (12.7-429), with significant additive interaction.ConclusionsLPCs in early pregnancy were associated with GDM risk. Low DCA or GUDCA greatly amplified the effect of high LPC18:0 on GDM, and its molecular mechanism is worth further investigations

Determination of reference intervals of serum levels of human epididymis protein 4 (HE4) in Chinese women

The detailed numbers of subjects from different centers. (DOCX 17.3 kb

Quarantine Methods and Prevention of Secondary Outbreak of Pandemic (H1N1) 2009

Quarantine Methods and Secondary Outbreak Preventio

Effects of various land utilization types on groundwater at different temporal scales: a case study of Huocheng plain, Xinjiang, China

Different land utilization types have unignorable impacts on adjacent aquifers, so studying the effects of varying land utilization types on groundwater balance and groundwater table in arid and semi-arid areas is crucial to facilitate the rational development of territorial space and groundwater resource management. This study investigated the relationship between land utilization type variations and groundwater dynamics from spatial and temporal scales in Huocheng plain, Xinjiang, China, via taking advantage of different land utilization maps provided by remote sensing techniques in 1990, 2000, and 2015. Based on the analysis of results, the findings can be summarized as follows. First, the cultivated and construction land has expanded significantly in the past 25 years. The migration of the regional center of cultivated land was insignificant, as it is still located almost in the center of the entire study area. However, the transfer span of the location center of construction land was more prominent, and its moving direction was mainly from south to northeast, directly affecting the groundwater balance state and groundwater table. Second, the total amount of groundwater storage exhibited a remarkable reduction, from a recharge in 1990 to a continuous discharge in 2000–2015, during which the total recharge and discharge had both continuously declined. Meanwhile, recharging and discharging elements were also changed profoundly as less groundwater recharges from ambient aqueous environments and more groundwater extraction. Thus, human activities were the fundamental driving terms causing the changes in groundwater sources. Third, the groundwater table gradually and continuously dropped from south to northeast in the study area over time. The drawdown of spatially averaged groundwater tables was positively correlated with construction and cultivated area extension. In addition, compared to the former literature, this study offers an alternative approach for groundwater protection and optimization of territorial space development and utilization in arid and semi-arid areas

Synthesis and Characterization of Organic Dyes Containing Various Donors and Acceptors

New organic dyes comprising carbazole, iminodibenzyl, or phenothiazine moieties, respectively, as the electron donors, and cyanoacetic acid or acrylic acid moieties as the electron acceptors/anchoring groups were synthesized and characterized. The influence of heteroatoms on carbazole, iminodibenzyl and phenothiazine donors, and cyano-substitution on the acid acceptor is evidenced by spectral, electrochemical, photovoltaic experiments, and density functional theory calculations. The phenothiazine dyes show solar-energy-to-electricity conversion efficiency (η) of 3.46–5.53%, whereas carbazole and iminodibenzyl dyes show η of 2.43% and 3.49%, respectively

Rapid assessment of knowledge, attitudes, practices, and risk perception related to the prevention and control of Ebola virus disease in three communities of Sierra Leone

Questionnaire on Ebola knowledge, attitudes, practices, and risk perception in three communities of Sierra Leone, 2015. (DOCX 34 kb

Biological Properties of Acidic Cosmetic Water from Seawater

This current work was to investigate the biological effects of acidic cosmetic water (ACW) on various biological assays. ACW was isolated from seawater and demonstrated several bio-functions at various concentration ranges. ACW showed a satisfactory effect against Staphylococcus aureus, which reduced 90% of bacterial growth after a 5-second exposure. We used cultured human peripheral blood mononuclear cells (PBMCs) to test the properties of ACW in inflammatory cytokine release, and it did not induce inflammatory cytokine release from un-stimulated, normal PBMCs. However, ACW was able to inhibit bacterial lipopolysaccharide (LPS)-induced inflammatory cytokine TNF-α released from PBMCs, showing an anti-inflammation potential. Furthermore, ACW did not stimulate the rat basophilic leukemia cell (RBL-2H3) related allergy response on de-granulation. Our data presented ACW with a strong anti-oxidative ability in a superoxide anion radical scavenging assay. In mass spectrometry information, magnesium and zinc ions demonstrated bio-functional detections for anti-inflammation as well as other metal ions such as potassium and calcium were observed. ACW also had minor tyrosinase and melanin decreasing activities in human epidermal melanocytes (HEMn-MP) without apparent cytotoxicity. In addition, the cell proliferation assay illustrated anti-growth and anti-migration effects of ACW on human skin melanoma cells (A375.S2) indicating that it exerted the anti-cancer potential against skin cancer. The results obtained from biological assays showed that ACW possessed multiple bioactivities, including anti-microorganism, anti-inflammation, allergy-free, antioxidant, anti-melanin and anticancer properties. To our knowledge, this was the first report presenting these bioactivities on ACW

Predictors of futile recanalization in basilar artery occlusion patients undergoing endovascular treatment: a post hoc analysis of the ATTENTION trial

BackgroundFew studies have focused on factors associated with futile recanalization in patients with an acute basilar artery occlusion (BAO) that was treated with modern endovascular therapy (EVT). The aim of this study was to explore the factors associated with futile recanalization in patients with an acute BAO presented within 12 h.MethodsThis is a post-hoc analysis of the ATTENTION trial (The Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion, ClinicalTrials.gov, number NCT 04751708). Demographics, clinical characteristics, acute stroke workflow interval times, and imaging characteristics were compared between the futile recanalization and favorable recanalization groups. The favorable outcome was defined as a modified Rankin scale (mRS) score of 0–3 at 90 days, successful reperfusion was defined as thrombolysis in cerebral infarction (TICI) 2b and 3 on the final angiogram, and futile recanalization was defined as failure to achieve a favorable outcome despite successful reperfusion. A multivariate analysis was performed to identify the predictors of futile recanalization.ResultsIn total, 185 patients were included in the final analysis: 89 (48.1%) patients had futile recanalization and 96 (51.9%) patients had favorable recanalization. In the multivariable logistic regression analysis, older age (OR 1.04, 95% CI 1.01 to 1.08, p = 0.01) and diabetes mellitus (OR 3.35, 95% CI 1.40 to 8.01, p = 0.007) were independent predictors of futile recanalization.ConclusionFutile recanalization occurred in nearly half of patients with acute BAO following endovascular treatment. Old age and diabetes mellitus were identified as independent predictors of futile recanalization after endovascular therapy for acute BAO