6,971 research outputs found
Recommended from our members
Standardization and the production of justice in summary criminal courts: a post human analysis
Since the 1980s, successive governments have become increasingly distrustful of professional judgment in those services which remain funded by the state, including the criminal justice system. Against this background, governments sought to increase efficiency in summary criminal courts. One way that this seems to have occurred is via the use of standardized forms in case progression. During 2013, Welsh conducted empirical research in which the reliance placed on standardized case management forms became apparent. We argue, drawing on post-humanist vocabularies to inform our analytic framework, that such documents may have shifted the temporality of summary criminal justice, which has the (perhaps unintended) consequence of (further) marginalizing defendant participation and limiting the types of legal issue that are litigated. These documents and processes, therefore, participate in the development of a particularized, and temporally situated, form of ājusticeā
Expressed sequence tag survey of gene expression in the scab mite Psoroptes ovis--allergens, proteases and free-radical scavengers
Out-of-sequence signal 3 as a mechanism for virus-induced immune suppression of CD8 T cell responses
Virus infections are known to induce a transient state of immune suppression often associated with an inhibition of T cell proliferation in response to mitogen or cognate-antigen stimulation. Recently, virus-induced immune suppression has been linked to responses to type 1 interferon (IFN), a signal 3 cytokine that normally can augment the proliferation and differentiation of T cells exposed to antigen (signal 1) and co-stimulation (signal 2). However, pre-exposure of CD8 T cells to IFN-inducers such as viruses or poly(IratioC) prior to antigen signaling is inhibitory, indicating that the timing of IFN exposure is of essence. We show here that CD8 T cells pretreated with poly(IratioC) down-regulated the IFN receptor, up-regulated suppressor of cytokine signaling 1 (SOCS1), and were refractory to IFNbeta-induced signal transducers and activators of transcription (STAT) phosphorylation. When exposed to a viral infection, these CD8 T cells behaved more like 2-signal than 3-signal T cells, showing defects in short lived effector cell differentiation, reduced effector function, delayed cell division, and reduced levels of survival proteins. This suggests that IFN-pretreated CD8 T cells are unable to receive the positive effects that type 1 IFN provides as a signal 3 cytokine when delivered later in the signaling process. This desensitization mechanism may partially explain why vaccines function poorly in virus-infected individuals
Calculating the shear angle in orthogonal metal cutting from fundamental stress-strain-strain rate properties of the work material
An analysis of the orthogonal metal cutting process is made which
enables the shear angle to be calculated from certain fundamental properties
of the work material and the specified cutting conditions. Shear angles
are calculated for a range of cutting conditions and good agreement is
shown between theory and experiment. In particular, such trends as the
decrease in shear angle with decrease in cutting speed and the tendency
for the chip to become discontinuous at slow cutting speeds which are found
experimentally and cannot be explained in terms of previous shear angle
analyses, are shown to be consistent with the present analysis
Preliminary report on the analysis of the stresses in a die-bolster combination
An analysis is presented of the stresses in a carbide die-steel
bolster combination. Results from a computer treatment of this analysis
are given in tabular and graphical form. Suggestions are made as to the
choice of interface diameters, and a nomogram is drawn enabling the maximum
allowable interference to be selected
High ions towards white dwarfs: circumstellar line shifts and stellar temperature
Based on a compilation of OVI, CIV, SiIV and NV data from IUE, FUSE, GHRS,
STIS, and COS, we derive an anti- correlation between the stellar temperature
and the high ion velocity shift w.r.t. to the photosphere, with positive (resp.
negative) velocity shifts for the cooler (resp. hotter) white dwarfs. This
trend probably reflects more than a single process, however such a dependence
on the WD's temperature again favors a CS origin for a very large fraction of
those ion absorptions, previously observed with IUE, HST-STIS, HST-GHRS, FUSE,
and now COS, selecting objects for which absorption line radial velocities,
stellar effective temperature and photospheric velocity can be found in the
literature. Interestingly, and gas in near-equilibrium in the star vicinity. It
is also probably significant that the temperature that corresponds to a null
radial velocity, i.e. \simeq 50,000K, also corresponds to the threshold below
which there is a dichotomy between pure or heavy elements atmospheres as well
as some temperature estimates for and a form of balance between radiation
pressure and gravitation. This is consistent with ubiquitous evaporation of
orbiting dusty material. Together with the fact that the fraction of stars with
(red-or blue-) shifted lines and the fraction of stars known to possess heavy
species in their atmosphere are of the same order, such a velocity-temperature
relationship is consistent with quasi-continuous evaporation of orbiting CS
dusty material, followed by accretion and settling down in the photosphere. In
view of these results, ion measurements close to the photospheric or the IS
velocity should be interpreted with caution, especially for stars at
intermediate temperatures. While tracing CS gas, they may be erroneously
attributed to photospheric material or to the ISM, explaining the difficulty of
finding a coherent pattern of the high ions in the local IS 3D distribution.Comment: Accepted by A&A. Body of paper identical to v1. This submission has a
more appropriate truncation of the original abstrac
Comment on ``Validity of certain soft-photon amplitudes''
The criteria suggested by Welsh and Fearing (nucl-th/9606040) to judge the
validity of certain soft-photon amplitudes are examined. We comment on aspects
of their analysis which lead to incorrect conclusions about published
amplitudes and point out important criteria which were omitted from their
analysis.Comment: 6 pages plus 1 postscript figure, Revte
Computing a Knot Invariant as a Constraint Satisfaction Problem
We point out the connection between mathematical knot theory and spin
glass/search problem. In particular, we present a statistical mechanical
formulation of the problem of computing a knot invariant; p-colorability
problem, which provides an algorithm to find the solution. The method also
allows one to get some deeper insight into the structural complexity of knots,
which is expected to be related with the landscape structure of constraint
satisfaction problem.Comment: 6 pages, 3 figures, submitted to short note in Journal of Physical
Society of Japa
On the fundamental group of the complement of a complex hyperplane arrangement
We construct two combinatorially equivalent line arrangements in the complex
projective plane such that the fundamental groups of their complements are not
isomorphic. The proof uses a new invariant of the fundamental group of the
complement to a line arrangement of a given combinatorial type with respect to
isomorphisms inducing the canonical isomorphism of the first homology groups.Comment: 12 pages, Latex2e with AMSLaTeX 1.2, no figures; this last version is
almost the same as published in Functional Analysis and its Applications 45:2
(2011), 137-14
- ā¦