Stocks and Sources of Carbon Buried in the Salt Marshes and Seagrass Beds of Patos Lagoon, Southern Brazil

This thesis investigates carbon source and stocks in salt marshes and seagrass beds in the Patos Lagoon estuary, the largest choked lagoon in the world, located in Southern Brazil. The study was conducted in the mesohaline region, at three shallow shoals. At each shoal, three sediment cores (50 cm deep) and plant biomass samples (aboveground and belowground) were collected along a transect line, spanning from the marsh to seagrass beds or unvegetated sediments (total = 9 sediment cores). The 50cm cores were subsampled and analyzed for organic carbon and nitrogen content, C/N ratios, and the isotope ratios of 13C/12C, and 15N/14N. Geochemical data in marsh sediments generally reflect the overlying vegetation indicating that the carbon source is largely from the in situ vegetation. Seagrass and tidal flat sediments have similar isotopic signatures and likely represent a mix carbon source of seagrass, phytoplankton, and macroalgae. Total carbon stocks for marshes (50cm depth) range from 97 to 221 MgC/ha. Seagrasses and tidal sediments have similar values and range from 9 to 57MgC/ha. These estimates are comparable to global values and indicate the importance of these ecosystems as carbon sinks. Initial rough calculations of ecosystem carbon stocks for the total area of marshes and seagrass beds in Patos Lagoon are 2,800 to 13,000MgC and 800 to 2,000 MgC, respectively. The size of these stocks emphasize the fact that these ecosystems are significant uncounted carbon sinks in Brazil that should be conserved and potentially utilized in Brazil’s active carbon market

The Metaphysics of Sex and Gender : Human Embodiment, Multiplicity, and Contingency

Thesis advisor: Patrick H. ByrneThis dissertation assesses the relevance and significance of Lonergan’s work to feminist philosophy. In particular, this work examines the debate between several contemporary feminist philosophers regarding the question of the relation between sex and gender, as well as their critiques of the Western metaphysical tradition. Ultimately, the trajectory of the work argues that Lonergan’s philosophy, in particular his re-envisioning of the meaning of what it is to do metaphysics, provides a unique and compelling response to the critiques made by feminist philosophers, despite the appearance of overt sexism in his writing. In fact, Lonergan’s approach clarifies the relevance of metaphysical thinking to feminist philosophical analysis. The first chapter examines likely feminist criticisms of Lonergan’s philosophy, as well as points of commonality, particularly between Lonergan’s cognitional theory and various feminist epistemologies. In particular, this chapter undertakes an analysis of Lonergan’s notion of “the pure desire to know” which he claims is a primordial, normative human response to our experience of the universe of being. Chapter Two focuses on the feminist debate regarding the “sex/gender” distinction. This chapter examines the analyses of sex and gender by four prominent feminist philosophers, Luce Irigaray, Elizabeth Grosz, Moira Gatens, and Judith Butler, and their critiques of the Western metaphysical tradition. Chapter Three explicates Lonergan’s cognitional theory, as well as his analysis of four patterns of experience – the biological, aesthetic, intellectual and dramatic. In addition, the notion of “neural demands” developed by Lonergan is discussed, as well as the connection between “neural demand functions” and patterns of experience. Chapter Four is dedicated to an exploration of the complexity of Lonergan’s approach to metaphysics. The chapter begins with Lonergan’s notion of being, and moves on to explore his notions of finality, emergent probability and objectivity. I turn next to a discussion of Lonergan’s revision of the traditional metaphysical vocabulary of potency, form, and act. This is followed by an examination of Lonergan’s understanding of the relationship between metaphysics and development, as well as dialectic. Chapter Five elaborates a dialectical exchange between Lonergan’s philosophy and the philosophy of Irigaray, Grosz, Butler, and Gatens. In addition, this chapter articulates Lonergan’s notion of anti-essentialism, and argues that his unmistakably clear rejection of essentialism supports the repudiation of the idea that human natures are fixed and determined by biological sex. In addition, Chapter Five explores the metaphysical and ethical significance of classical and statistical law, as well as the relationship between metaphysics and ethics as it pertains to feminist philosophy.Thesis (PhD) — Boston College, 2008.Submitted to: Boston College. Graduate School of Arts and Sciences.Discipline: Philosophy

High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus

Diabetic complications include infection and cardiovascular disease. Within the immune system, host-pathogen and regulatory host-host interactions operate through binding of oligosaccharides by C-type lectin. A number of C-type lectins recognise oligosaccharides rich in mannose and fucose – sugars with similar structures to glucose. This raises the possibility that high glucose conditions in diabetes affect protein-oligosaccharide interactions via competitive inhibition. Mannose binding lectin, soluble DC-SIGN & DC-SIGNR, and surfactant protein D, were tested for carbohydrate binding in the presence of glucose concentrations typical of diabetes, via surface plasmon resonance and affinity chromatography. Complement activation assays were performed in high glucose. DC-SIGN and DC-SIGNR expression in adipose tissues was examined via immunohistochemistry. High glucose inhibited C-type lectin binding to high-mannose glycoprotein and binding of DC-SIGN to fucosylated ligand (blood group B) was abrogated in high glucose. Complement activation via the lectin pathway was inhibited in high glucose and also in high trehalose - a nonreducing sugar with glucoside stereochemistry. DC-SIGN staining was seen on cells with DC morphology within omental and subcutaneous adipose tissues. We conclude that high glucose disrupts C-type lectin function, potentially illuminating new perspectives on susceptibility to infectious and inflammatory disease in diabetes. Mechanisms involve competitive inhibition of carbohydrate-binding within sets of defined proteins, in contrast to broadly indiscriminate, irreversible glycation of proteins

Death and the artificial placenta

Artificial Amnion and Placenta Technology (AAPT)—sometimes referred to as ‘Artificial Womb Technology’—could provide an extracorporeal alternative to bodily gestations, allowing a fetus delivered prematurely from the human uterus to continue development while maintaining fetal physiology. As AAPT moves nearer to being used in humans, important ethical and legal questions remain unanswered. In this paper, we explore how the death of the entity sustained by AAPT would be characterized in law. This question matters, as legal ambiguity in this area has the potential to compound uncertainty and the suffering of newly bereaved parent(s). We first identify the existing criteria used to delineate the legal characterization of death, which occurs before birth or during the immediate neonatal period in England and Wales. We then demonstrate that attempting to apply these in the context of AAPT gives rise to a number of challenges, which make it impossible to reach a definitive conclusion as to the nature of death in AAPT using the current legal framework. In doing so, we demonstrate that the current legal framework in England and Wales may be unable to adequately capture the situation of an entity being sustained by AAPT

Effect of a Pre-Dinner Walnut Snack on Nutrient Intake Among University Students

https://openriver.winona.edu/urc2018/1021/thumbnail.jp

Neural Impact of Neighborhood Socioeconomic Disadvantage in Traumatically Injured Adults

Nearly 14 percent of Americans live in a socioeconomically disadvantaged neighborhood. Lower individual socioeconomic position (iSEP) has been linked to increased exposure to trauma and stress, as well as to alterations in brain structure and function; however, the neural effects of neighborhood SEP (nSEP) factors, such as neighborhood disadvantage, are unclear. Using a multi-modal approach with participants who recently experienced a traumatic injury (N = 185), we investigated the impact of neighborhood disadvantage, acute post-traumatic stress symptoms, and iSEP on brain structure and functional connectivity at rest. After controlling for iSEP, demographic variables, and acute PTSD symptoms, nSEP was associated with decreased volume and alterations of resting-state functional connectivity in structures implicated in affective processing, including the insula, ventromedial prefrontal cortex, amygdala, and hippocampus. Even in individuals who have recently experienced a traumatic injury, and after accounting for iSEP, the impact of living in a disadvantaged neighborhood is apparent, particularly in brain regions critical for experiencing and regulating emotion. These results should inform future research investigating how various levels of socioeconomic circumstances may impact recovery after a traumatic injury as well as policies and community-developed interventions aimed at reducing the impact of socioeconomic stressors

Intestinal parasitism among waste pickers in Mato Grosso do Sul, Midwest Brazil

The purpose of this study was to estimate the prevalence of intestinal parasites in both cooperative-affiliated and independent waste pickers operating at the municipal sanitary landfill in Campo Grande, Mato Grosso do Sul, Brazil, and associate these findings with hemoglobin, eosinophils, vitamin A and C levels and interleukin 5 and 10 (IL-5 and IL-10) production. Biological samples were collected, in addition to clinical, epidemiological, and sociodemographic data. Stool analyzes were based on sedimentation by centrifugation and on spontaneous sedimentation. High-performance liquid chromatography was used to determine vitamin A and C levels. ELISA was employed to quantify interleukins. Intestinal parasites were found in 29 of the 66 subjects assessed (43.9%). Endolimax nana (22.7%), Entamoeba coli (21.1%), Giardia lamblia (6.1%), Entamoeba histolytica/E. dispar (4.5%), and Ascaris lumbricoides (4.5%) were the most prevalent species. Pathogenic parasites were detected in 11 individuals (16.7%). Hypovitaminoses A and C were detected in 19.6% (13/66) and 98.4% (65/66) of subjects, respectively. IL-5 and IL-10 production was observed in 21 (31.8%) and 32 (48.4%) subjects, respectively. Infection with pathogenic intestinal parasites was not a cause of vitamin A and C deficiency or IL-5 and IL-10 production among these workers

Post-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long-acting injection, I: analysis of cases

<p>Abstract</p> <p>Background</p> <p>An advance in the treatment of schizophrenia is the development of long-acting intramuscular formulations of antipsychotics, such as olanzapine long-acting injection (LAI). During clinical trials, a post-injection syndrome characterized by signs of delirium and/or excessive sedation was identified in a small percentage of patients following injection with olanzapine LAI.</p> <p>Methods</p> <p>Safety data from all completed and ongoing trials of olanzapine LAI were reviewed for possible cases of this post-injection syndrome. Descriptive analyses were conducted to characterize incidence, clinical presentation, and outcome. Regression analyses were conducted to assess possible risk factors.</p> <p>Results</p> <p>Based on approximately 45,000 olanzapine LAI injections given to 2054 patients in clinical trials through 14 October 2008, post-injection delirium/sedation syndrome occurred in approximately 0.07% of injections or 1.4% of patients (30 cases in 29 patients). Symptomatology was consistent with olanzapine overdose (e.g., sedation, confusion, slurred speech, altered gait, or unconsciousness). However, no clinically significant decreases in vital signs were observed. Symptom onset ranged from immediate to 3 to 5 hours post injection, with a median onset time of 25 minutes post injection. All patients recovered within 1.5 to 72 hours, and the majority continued to receive further olanzapine LAI injections following the event. No clear risk factors were identified.</p> <p>Conclusions</p> <p>Post-injection delirium/sedation syndrome can be readily identified based on symptom presentation, progression, and temporal relationship to the injection, and is consistent with olanzapine overdose following probable accidental intravascular injection of a portion of the olanzapine LAI dose. Although there is no specific antidote for olanzapine overdose, patients can be treated symptomatically as needed. Special precautions include use of proper injection technique and a post-injection observation period.</p> <p>Trial Registration</p> <p>ClinicalTrials.gov ID; URL: <url>http://http//www.clinicaltrials.gov/</url>: NCT00094640, NCT00088478, NCT00088491, NCT00088465, and NCT00320489.</p

Health Status of Visitors and Temporary Residents, United States

Education, policy, and interventions to promote visitor health are needed