Determining Cycle Times for Packing in Distribution Centres

Scope of this work is to determine cycle time formulas for packing in distribution centres. No such formulas exist today, even if it is the second most important process after picking. Based on examining packing, morphological boxes showing time influencing parameters are derived. The most significant parameters are identified using analysis of variance (ANOVA). Cycle times are determined and applied to cases. These prove that the formulas can be used to calculate the time required for packing

The Effects of Deployments and Other Factors on Air Force Junior Officer Retention

The Air Force is dedicated to supporting the Combatant Commander through the use of Individual Augmentees (IAs) to fulfill joint mission requirements. Previous studies have explored how deployments affect retention; however, there has not been a great deal of focus on how IA deployments affect retention for Junior Air Force Officers in the Logistics, Support, Operations, Acquisitions, and Special Investigations career groups. This research utilizes the Individual Deployer (ID) definition to identify IAs through Personnel, Pay, and Deployment data provided by the Defense Manpower Data Center (DMDC) from 2003-2009. Logistics Regression analysis was conducted to determine the effect of deployments on the odds of retention. Other independent variables consistent with the literature, such as Marital Status, Gender, Pay Grade, Commissioning Source, Deployment Type, and Career Group, also were observed to determine how they affect the odds of retention for Air Force Junior Officers. Survey responses drawn from Status of Forces surveys spanning fiscal years 2003-2009 were analyzed and compared and contrasted with the logistic regression results. This research develops analytical models for decision makers that identify factors that affect retention. Results show that the odds of retention increase for Males, personnel who are married, and personnel in the Logistics Career Group. The odds of retention decrease for Females, personnel in the Support Career Group, and personnel who commission through ROTC

A Brazilian glycoprotein E-negative bovine herpesvirus type 1.2a (BHV-1.2a) mutant is attenuated for cattle and induces protection against wild-type virus challenge

The authors previously reported the construction of a glycoprotein E-deleted (gE-) mutant of bovine herpesvirus type 1.2a (BHV-1.2a). This mutant, 265gE-, was designed as a vaccinal strain for differential vaccines, allowing the distinction between vaccinated and naturally infected cattle. In order to determine the safety and efficacy of this candidate vaccine virus, a group of calves was inoculated with 265gE-. The virus was detected in secretions of inoculated calves to lower titres and for a shorter period than the parental virus inoculated in control calves. Twenty one days after inoculation, the calves were challenged with the wild type parental virus. Only mild signs of infection were detected on vaccinated calves, whereas non-vaccinated controls displayed intense rhinotracheitis and shed virus for longer and to higher titres than vaccinated calves. Six months after vaccination, both vaccinated and control groups were subjected to reactivation of potentially latent virus. The mutant 265gE- could not be reactivated from vaccinated calves. The clinical signs observed, following the reactivation of the parental virus, were again much milder on vaccinated than on non-vaccinated calves. Moreover, parental virus shedding was considerably reduced on vaccinated calves at reactivation. In view of its attenuation, immunogenicity and protective effect upon challenge and reactivation with a virulent BHV-1, the mutant 265gE- was shown to be suitable for use as a BHV-1 differential vaccine viru

Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa.

RNA isolated from the glands of a Delta(9)-tetrahydrocannabinolic acid (THCA)-producing strain of Cannabis sativa was used to generate a cDNA library containing over 100 000 expressed sequence tags (ESTs). Sequencing of over 2000 clones from the library resulted in the identification of over 1000 unigenes. Candidate genes for almost every step in the biochemical pathways leading from primary metabolites to THCA were identified. Quantitative PCR analysis suggested that many of the pathway genes are preferentially expressed in the glands. Hexanoyl-CoA, one of the metabolites required for THCA synthesis, could be made via either de novo fatty acids synthesis or via the breakdown of existing lipids. qPCR analysis supported the de novo pathway. Many of the ESTs encode transcription factors and two putative MYB genes were identified that were preferentially expressed in glands. Given the similarity of the Cannabis MYB genes to those in other species with known functions, these Cannabis MYBs may play roles in regulating gland development and THCA synthesis. Three candidates for the polyketide synthase (PKS) gene responsible for the first committed step in the pathway to THCA were characterized in more detail. One of these was identical to a previously reported chalcone synthase (CHS) and was found to have CHS activity. All three could use malonyl-CoA and hexanoyl-CoA as substrates, including the CHS, but reaction conditions were not identified that allowed for the production of olivetolic acid (the proposed product of the PKS activity needed for THCA synthesis). One of the PKS candidates was highly and specifically expressed in glands (relative to whole leaves) and, on the basis of these expression data, it is proposed to be the most likely PKS responsible for olivetolic acid synthesis in Cannabis glands

Results of the German Software Industry Survey 2013

This is the second year that we execute the Software Industry Survey in Germany and publish a report with the main results. As formulated in 2012, our goal is to investigate the current state of the German software industry on a yearly basis. Conclusions are made based on grounded data and empirical findings. We hope that this type of research will contribute to the work of both, practitioners and researchers