5,381 research outputs found
QCD Sum Rule Analysis of Heavy Quarkonium Hybrids
We have studied the charmonium and bottomonium hybrid states with various
quantum numbers in QCD sum rules. At leading order in , the
two-point correlation functions have been calculated up to dimension six
including the tri-gluon condensate and four-quark condensate. After performing
the QCD sum rule analysis, we have confirmed that the dimension six condensates
can stabilize the hybrid sum rules and allow the reliable mass predictions. We
have updated the mass spectra of the charmonium and bottomonium hybrid states
and identified that the negative-parity states with form the lightest hybrid supermultiplet while the positive-parity
states with belong to a heavier hybrid
supermultiplet.Comment: 7 pages, 1 figures. Some minor edits have been made. Presentation at
the DPF 2013 Meeting of the American Physical Society Division of Particles
and Fields, Santa Cruz, California, August 13-17, 201
Exploring the Spectrum of Heavy Quarkonium Hybrids with QCD Sum Rules
QCD Laplace sum rules are used to calculate heavy quarkonium (charmonium and
bottomonium) hybrid masses in several distinct channels. Previous
studies of heavy quarkonium hybrids did not include the effects of
dimension-six condensates, leading to unstable sum rules and unreliable mass
predictions in some channels. We have updated these sum rules to include
dimension-six condensates, providing new mass predictions for the spectra of
heavy quarkonium hybrids. We confirm the finding of other approaches that the
negative-parity states form the lightest hybrid
supermultiplet and the positive-parity
states are members of a heavier supermultiplet. Our results disfavor a pure
charmonium hybrid interpretation of the , in agreement with previous
work.Comment: Presented by RTK at the Theory Canada 9 Conference, held at Wilfrid
Laurier University in June 2014. Submitted for the conference proceedings to
be published in the Canadian Journal of Physics. 5 pages, 1 figure. Version
2: reference added, typo correcte
Quantum and classical Floquet prethermalization
Time-periodic (Floquet) driving is a powerful way to control the dynamics of
complex systems, which can be used to induce a plethora of new physical
phenomena. However, when applied to many-body systems, Floquet driving can also
cause heating, and lead to a featureless infinite-temperature state, hindering
most useful applications. It is therefore important to find mechanisms to
suppress such effects. Floquet prethermalization refers to the phenomenon where
many-body systems subject to a high-frequency periodic drive avoid heating for
very long times, instead tending to transient states that can host interesting
physics. Its key signature is a strong parametric suppression of the heating
rate as a function of the driving frequency. Here, we review our present
understanding of this phenomenon in both quantum and classical systems, and
across various models and methods. In particular, we present rigorous theorems
underpinning Floquet prethermalization in quantum spin and fermionic lattice
systems, extensions to systems with degrees of freedom that have unbounded
local dimension. Further, we briefly describe applications to novel
nonequilibrium phases of matter, and recent experiments probing
prethermalization with quantum simulators. We close by describing the frontiers
of Floquet prethermalization beyond strictly time-periodic drives, including
time-quasiperiodic driving and long-lived quasi-conserved quantities enabled by
large separation of energy scales.Comment: review paper, 15 pages, comments are welcom
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An Antibody-Based Leukocyte-Capture Microarray for the Diagnosis of Systemic Lupus Erythematosus
The diagnosis of Systemic Lupus Erythematosus (SLE) is challenging due to its heterogeneous clinical presentation and the lack of robust biomarkers to distinguish it from other autoimmune diseases. Further, currently used laboratory tests do not readily distinguish active and inactive disease. Several groups have attempted to apply emerging high throughput profiling technologies to diagnose and monitor SLE. Despite showing promise, many are expensive and technically challenging for routine clinical use. The goal of this work is to develop a better diagnostic and monitoring tool for SLE. We report a highly customisable antibody microarray that consists of a duplicate arrangement of 82 antibodies directed against surface antigens on peripheral blood mononuclear cells (PMBCs). This high-throughput array was used to profile SLE patients (n = 60) with varying disease activity, compared to healthy controls (n = 24), patients with rheumatoid arthritis (n = 25), and other autoimmune diseases (n = 28). We used a computational algorithm to calculate a score from the entire microarray profile and correlated it with SLE disease activity. Our results demonstrate that leukocyte-capture microarray profiles can readily distinguish active SLE patients from healthy controls (AUROC = 0.84). When combined with the standard laboratory tests (serum anti-dsDNA, complements C3 and C4), the microarrays provide significantly increased discrimination. The antibody microarrays can be enhanced by the addition of other markers for potential application to the diagnosis and stratification of SLE, paving the way for the customised and accurate diagnosis and monitoring of SLE
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Observer-Based PID Security Control for Discrete Time-Delay Systems under Cyber-Attacks
National Natural Science Foundation of China under Grant 61873148, Grant 61873169, and Grant 61933007; Research Grants Council of Hong Kong Special Administrative Region under Grant 9042223 and Grant CityU 11200717; Alexander von Humboldt Foundation of Germany
Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes
Unlike conventional major histocompatibility complex–restricted T cells, Vα14-Jα18 NKT cell lineage precursors engage in cognate interactions with CD1d-expressing bone marrow–derived cells that are both necessary and sufficient for their thymic selection and differentiation, but the nature and sequence of these interactions remain partially understood. After positive selection mediated by CD1d-expressing cortical thymocytes, the mature NKT cell lineage undergoes a series of changes suggesting antigen priming by a professional antigen-presenting cell, including extensive cell division, acquisition of a memory phenotype, the ability to produce interleukin-4 and interferon-γ, and the expression of a panoply of NK receptors. By using a combined transgenic and chimeric approach to restrict CD1d expression to cortical thymocytes and to prevent expression on other hematopoietic cell types such as dendritic cells, macrophages, or B cells, we found that, to a large extent, expansion and differentiation events could be imparted by a single-cognate interaction with CD1d-expressing cortical thymocytes. These surprising findings suggest that, unlike thymic epithelial cells, cortical thymocytes can provide unexpected, cell type–specific signals leading to lineage expansion and NKT cell differentiation
Small angle neutron scattering from single-wall carbon nanotube suspensions: evidence for isolated rigid rods and rod networks
We report small angle neutron scattering (SANS) from dilute suspensions of purified individual single wall carbon nanotubes (SWNTs) in D2O with added sodium dodecylbenzene sulfonate (NaDDBS) ionic surfactant. The scattered intensity scales as Q-1 for scattered wave vector, Q, in the range 0.005 \u3c Q \u3c 0.02 Ã…-1. The Q-1 behavior is characteristic of isolated rigid rods. A crossover of the scattered intensity power law dependence from Q-1 to Q-2 is observed at ~0.004 Ã…-1, suggesting the SWNTs form a loose network at 0.1 wt% with a mesh size of ~160 nm. SANS profiles from several other dispersions of SWNTs do not exhibit isolated rigid rod behavior; evidently the SWNTs in these systems are not isolated and form aggregates
Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe
We developed a technique for electrochemical detection of salivary mRNA employing a hairpin probe (HP). Steric hindrance (SH) suppresses unspecific signal and generates a signal-on amplification process for target detection. The stem-loop configuration brings the reporter end of the probe into close proximity with the surface and makes it unavailable for binding with the mediator. Target binding opens the hairpin structure of the probe, and the mediator can then bind to the accessible reporter. Horseradish peroxidase is utilized to generate electrochemical signal. This signal-on process is characterized by a low basal signal, a strong positive readout and a large dynamic range. The SH is controlled via hairpin design and electrical field. By applying electric field control to HPs, the limit of detection of RNA is about 0.4 fM, which is 10 000-fold more sensitive than conventional linear probes. Endogenous Interleukin-8 mRNA is detected with the HP, and good correlation with the quantitative PCR technique is obtained. The resultant process allows a simple setup and by reducing the number of steps it is suited for the point-of-care detection of specific nucleic acid sequences from complex body fluids such as saliva
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