16 research outputs found
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.
BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700
The application of multiple random earthquake simulations to probabilistic seismic hazard assessment in the Aegean region
A ground motion logic tree for seismic hazard analysis in the stable cratonic region of Europe: regionalisation, model selection and development of a scaled backbone approach
In Search of the Theory of Harm in EU Consumer Law: Lessons from the Consumer Fitness Check
ecently, EU Consumer law has undergone a ‘Fitness Check’ (or REFIT). We thought that checking the fitness for purpose of a body of law would involve revisiting its purpose. This is why we expected to find in the rich REFIT documentation (over 4000 pages of studies and Commission documents) an explicit discourse on the goals of consumer law. Our aim was to connect this discourse to two lines of scholarship: a doctrinal line pointing out that EU consumer law lacks a clear direction and that, to the extent it does have one, it is too strongly geared towards market integration to the detriment of protection of the weakest, and an economically informed approach seeking to formulate a theory of harm that could underpin the enforcement of consumer law, by analogy with the practice in competition law. We agree that a clearer direction and a stronger conceptualisation of what harms the law seeks to protect consumers against would improve EU consumer law. This paper defines a ‘theory of harm’, illustrates what a theory of harm for consumer law could look like and analyses the REFIT documentation in search for elements of such a theory. Our findings are largely disappointing. We looked for something that is not there. The REFIT’s tour de force is to check fitness for purpose without discussing purpose. It does so by adopting a circular approach and defining consumer harm as instances of under-enforcement of the law. This presupposes that all possible harms are already accounted for in the law and only occur when the law is not properly enforced. We uncover an irony instead of a theory of harm. What the REFIT does delineate is a normative space in which to develop a theory of harm for the future. It consists of a virtuous triangle of empowerment, trust and a well-functioning internal market. The REFIT also suggests that an economic-based theory of harm would need to interact with several legal elements. Consumer weakness, empowerment and legitimate expectations constitute ingredients for an economically grounded, behaviourally sensible and legally workable theory of harm
A regionally-adaptable “scaled backbone” ground motion logic tree for shallow seismicity in Europe: application to the 2020 European seismic hazard model
<jats:title>Abstract</jats:title><jats:p>The selection of ground motion models, and the representation of their epistemic uncertainty in the form of a logic tree, is one of the fundamental components of probabilistic seismic hazard and risk analysis. A new ground motion model (GMM) logic tree has been developed for the 2020 European seismic hazard model, which develops upon recently compiled ground motion data sets in Europe. In contrast to previous European seismic hazard models, the new ground model logic tree is built around the scaled backbone concept. Epistemic uncertainties are represented as calibrations to a reference model and aim to characterise the potential distributions of median ground motions resulting from variability in source scaling and attenuation. These scaled backbone logic trees are developed and presented for shallow crustal seismic sources in Europe. Using the new European strong motion flatfile, and capitalising on recent perspectives in ground motion modelling in the scientific literature, a general and transferable procedure is presented for the construction of a backbone model and the regionalisation of epistemic uncertainty. This innovative approach forms a general framework for revising and updating the GMM logic tree at national and European scale as new strong motion data emerge in the future.</jats:p>