484 research outputs found
The Epidermal Characteristics of the First Seedling Leaves of Certain Grass Seedlings
- Author
- Publication venue
- FHSU Scholars Repository
- Publication date
- 29/01/1962
- Field of study
The epidermal characteristics of the first seeding l eaves of thirty species of grasses common to the mixed Prairie Association of West central Kansas were studied. The thirty species represent seventeen genera and six tribes of the Gramineae. Seed was gathered in the Hays, Kansas area and the seedlings grown in the Fort Hays Kansas State College greenhouse under optimum conditions. Slides of both abaxial (lower) and adaxial (upper) leaf surfaces were made from preserved specimens by the peel method which utilizes acetone and cellulose acetate film. These slides were compared with stained mounts of the abaxial epidermis. Photomicrography of both leaf surfaces were taken and these supplemented with line drawing of certain diagnostic epidermal elements. The differing cell types occurring as part of the epidermis were studied and recorded. Silica bodies, cork cells, macro-hairs, micro-hairs, prickle hairs, papillae, stomata, and certain undifferentiated cells were studied. The form or shape of these epidermal elements was emphasized rather than the number or distribution. The form of the silica bodies and bicellular microhairs were found to be most useful in distinguishing or characterizing species and other taxa. In this survey of a number of grasses of several genera and tribes, the form and arrangement of the epidermal elements were found to be more diagnostic than distribution or frequency
RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia—an international Delphi consensus
- Author
- Aarsland Dag
- Ballard Clive
- Blanc Frederic
- Boeve Bradley
- Brooks David J
- Chaudhuri K Ray
- Chouliaras Leonidas
- Cummings Jeffrey
- Feldman Howard H
- Flicker Leon
- Galvin James E
- Grosset Donald G
- Ikeda Manabu
- Kohlhaas Susan
- Lawlor Brian
- Lemstra Afina W
- Leroi Iracema
- Leverenz James B
- Lewis Simon
- Londos Elisabet
- McKeith Ian
- Mills Roger
- Oakley Richard
- O’Brien John T
- Richardson Jill
- Sabbagh Marwan
- Skidmore John
- Sultana Janet
- Svennigsson Per
- Taylor John-Paul
- Tiraboschi Pietro
- Walker Zuzana
- Watson Rosie
- Weil Rimona S
- Weintraub Daniel
- Williams-Gray Caroline H
- Yarnall Alison
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 11/11/2022
- Field of study
Drug repositioning and repurposing has proved useful in identifying new treatments for many diseases, which can then rapidly be brought into clinical practice. Currently, there are few effective pharmacological treatments for Lewy body dementia (which includes both dementia with Lewy bodies and Parkinson’s disease dementia) apart from cholinesterase inhibitors. We reviewed several promising compounds that might potentially be disease-modifying agents for Lewy body dementia and then undertook an International Delphi consensus study to prioritise compounds. We identified ambroxol as the top ranked agent for repurposing and identified a further six agents from the classes of tyrosine kinase inhibitors, GLP-1 receptor agonists, and angiotensin receptor blockers that were rated by the majority of our expert panel as justifying a clinical trial. It would now be timely to take forward all these compounds to Phase II or III clinical trials in Lewy body dementia
ACC/AHA Guidelines for Coronary Angiography. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Coronary Angiography)
- Author
- Audet Anne-Marie
- Carabello Blase
- Cheitlin Melvin D.
- Dehmer Gregory J.
- Eagle Kim A.
- Faxon David P.
- Gardner Timothy J.
- Garson Arthur, Jr.
- Gibbons Raymond J.
- Legako Ronald D.
- Leon Donald F.
- Murray John A.
- Nissen Steven E.
- Pepine Carl J.
- Ritchie James L.
- Russell Richard O., Jr.
- Ryan Thomas J.
- Scanlon Patrick J.
- Smith Sidney C., Jr.
- Watson Rita M.
- Publication venue
- Publication date
- 01/01/1999
- Field of study
"The ACC/AHA Task Force on Practice Guidelines herein revises and updates the original “Guidelines for Coronary Angiography,” published in 1987 (1). The frequent and still-growing use of coronary angiography, its relatively high costs, its inherent risks and the ongoing evolution of its indications have given this revision urgency and priority. The expert committee appointed included private practitioners and academicians. Committee members were selected to represent both experts in coronary angiography and senior clinician consultants. Representatives from the family practice and internal medicine professions were also included on the committee. The English-language medical literature was searched for the 10 years preceding development of the guidelines. The searches yielded >1,600 references that the committee reviewed for relevance. Evidence relative to the use of coronary angiography was compiled and evaluated by the committee. Whereas randomized trials are often available for reference in the development of treatment guidelines, randomized trials regarding the use of diagnostic procedures such as coronary angiography are rarely available (2). For development of these guidelines, when coronary angiography was a necessary procedure in describing a clinical subset or in choosing a course of treatment and that therapy was shown to have an advantage for the patient, especially in the context of a randomized trial, then the indication for angiography was given greater consideration than indications cited in less-rigorous evaluations of data.
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy
- Author
- A Kaldun Nossuli
- Aamir Jamal
- Adalbert Schiller
- Adam Cheifetz
- Adarsh Daswani
- Adeera Levin
- Adline Ghazi
- Adrian Guinsburg
- Adriana Cif
- Adriana Gabriela Onaca
- Adriana Ilavska
- Adriana Villarino
- Agarwal R.
- Agnieszka Starzec
- Ahmed Arif
- Ahmed Awad
- Aiping Yin
- Akimichi Asano
- Alan Jackson
- Alan McMahon
- Alan Perlman
- Alberto Di Carlo
- Alberto Esquenazi
- Alejandra Oviedo
- Alejandro Valdes Depeda
- Aleksandra Kendereski
- Alex Valenzuela
- Alexander Dreval
- Alexander Gonzalez
- Alexander Shinkov
- Alexander Turchin
- Alexandre Klein
- Alfonso Soto Gonzalez
- Alfred Penfornis
- Alfredo Chew Wong
- Alfredo Wassermann
- Ali Torshizi
- Alicia Chilito
- Alina Agafyina
- Alison Dawson
- Alva Hansraj
- Amer Al-Karadsheh
- Amorin Remus Popa
- Amrendra Kumar
- Amy Sprague
- Ana Limos
- Ana Maria Cusumano
- Ana Maria Elosegui
- Anabella Amigo
- Anatoliy Kazmirchuk
- Andrea Phillips
- Andrea Stella
- Andreas Maddux
- Andrej Dzupina
- Andres Alvarisqueta
- Andrew Johnson
- Andrew O'Shaughnessy
- Andrew Steele
- Andrian Yakov
- Andrzej Januszewicz
- Andrzej Madej
- Angelina Angelova
- Anibal Gastaldi
- Anil Gupta
- Anita Bhajan Manocha
- Anjanette Tan
- Anna Kaminska
- Anna Maria Veronelli
- Anna Strzelecka
- Anna Zateyshchikova
- Anselmo Bordonava
- Antanas Navickas
- Anthony Gunstone
- Anthony Roberts
- Antonio Ceriello
- Antonio Galan Serrano
- Antonio Scafuto Scotton
- Antonio Terrelonge
- Antônio Roberto Chacra
- Anupama Gowda
- Arjun D Sinha
- Armando Perez
- Ashot Mkrtumyan
- Atanas Koundurdjiev
- Augusto Vallejos
- Aurelian-Emil Ranetti
- Ayim Akyea-Djamson
- Aysha Badat
- Bakris G.
- Baldev Singh
- Barbara Greco
- Barbara Kaczmarek
- Barbara Rewerska
- Barry M Brenner
- Belia Martin Del Camp Blanco
- Bernard Zinman
- Bertrand Cariou
- Bertrand Dussol
- Bhasker Mehta
- Bhimavarapu Sudhakar
- Björn Paschen
- Bompoint S.
- Borys Mankovskyy
- Botond Csiky
- Boyan Nonchev
- Brenner B. M.
- Brett Kissela
- Brian Nichol
- Bruce Neal
- Bruce Trippe
- Bruno Geloneze Neto
- Bull S.
- Byung-Wan Lee
- C B Keshavamurthy
- Cannon C. P.
- Capuano G.
- Carlo Giorda
- Carlos Alberto Cuneo
- Carlos Arauz-Pacheco
- Carlos Barrera
- Carlos Perez
- Carmel Hawley
- Carmen Crisan
- Carol Pollock
- Carolyn Droste
- Caroucel Chuateco
- Caryl David
- Cecilia Garcia Ballesteros
- Cecilia Jimeno
- Celso Amodeo
- Cesar Javier Zaidman
- Cesar Yoiti Hayashida
- Chamberlain Obialo
- Chang-Hsun Hsieh
- Charles Cook
- Charles Kaupke
- Charytan D. M.
- Chek Loong Loh
- Chen Leia
- Cheol-Young Park
- Chih-Ching Lin
- Christopher P Cannon
- Christy Yao
- Chu P. -L.
- Chwen-Tzuei Chang
- Chye Lee Gan
- Clara Barrios
- Claude Galphin
- Claudia Goycoa
- Claudia Moreira de Brito
- Clodoaido Caringal
- Cristian Serafinceanu
- Cristina Toarba
- Cristobal Morales Portillo
- Csaba Kovesdy
- Cynthia Bowman-Stroud
- Cynthia Christiano
- Cynthia Mustieles Rocha
- Cyrus Desouza
- Cássio Slompo Ramos
- Dagmar Bartaskova
- Dale Crawford Allison
- Dalia Kozloviene
- Dan Scharfstein
- Dana Cosma
- Daniel Coyne
- Daniel Hiser
- Daniel Kolansky
- Daniel Panarotto
- Daniel Pella
- Daniel Weiner
- Daniil Chizhov
- Dariusz Sowinski
- Darren K McGuire
- Davesh Sennik
- David C Wheeler
- David Cherney 3rd
- David Gorson
- David Johnson
- David M Charytan
- David Packham
- David Scott
- David Wheeler
- De Zeeuw D.
- Debbie Cohen-Stein
- Debbie Mascaro
- Deepak Koppolu
- Dennis Levinson
- Derek Lewis
- Detian Li
- Devasmita Dev
- Devesh Patel
- Dewan Deepak
- Dick de Zeeuw
- Diego Aizenberg
- Dinesh Jain
- Dinesh Khullar
- Diogo Belo
- Dmitry Zateyshshikov
- Domenico Santoro
- Domingos d'Avila
- Donald Brandon
- Donald Fraser
- Dong-Wan Chae
- Dora Inés Molina de Salazar
- Dorota Mlodawska-Choluj
- Doru Negru
- Edgar Arcos
- Edoardo Mannucci
- Eduardo Farias
- Edward Watson
- Edwards R.
- Egle Gaupsiene
- Egle Urbanaviciene
- Ekaterina Velichkova
- Elena Christofides
- Elena Grineva
- Elena Kolmakova
- Elena Shutemova
- Eleonora Harcsa
- Elizabeth Barranco
- Elizabeth Gelersztein
- Elizabeth Kern
- Elizete Keitel
- Eloisa Tellez Chavez
- Emanuela Orsi
- Emil Martinka
- Emyr Davies
- Enrique Gonzalez
- Eric Alamartine
- Eric Hernandez Triana
- Eric Thervet
- Erick Turcios Juarez
- Esteban Cercos
- Eugenia Galindo-Ramos
- Eva Peterfai
- Evaly Chen
- Evandro de Souza Portes
- Evgueniy Vazelov
- Fabian Otreras
- Fabiana Loss de Carvalho Contieri
- Fabio Malberti
- Fadi Saba
- Fadlo Fraige Filho
- Favio Edmundo Enriquez Sosa
- Fayzal Ahmed
- Ferdinando Carlo Sasso
- Fernanco Augusto Alves da Costa
- Fernanda Cristina Camelo Sanches
- Fernando Cereto Castro
- Fernando Flores Lozano
- Fernando Jimenez Florez
- Fernando Krynski
- Fernando M Edwin
- Fernando Thomé
- Fernando Trespalacios
- Florence Santos
- Florencia Kraft
- Fracisco Javier Gonzalez Martinez
- Fran Morren
- Franciso Jose Tinahones Madueno
- Frank Eder
- Franklin Joseph
- Franklin Paul Haase
- Frantisek Saudek
- François Dubé
- François Madore
- Freemu Varghese
- Gabriela Cecilia Coloma
- Gabriela Genova-Hristova
- Gabriele von Ingersleben
- Gaetano Serviddio
- Galina Nagibovich
- Gary Meininger
- Gema Fernandez Fresnedo
- Georg Plassmann
- George Bakris
- George Hon
- George Newman
- Gerald DaRoza
- Gerald Keightley
- Gerry Tan
- Giacomo Garibotto
- Giorgio Fuiano
- Giovanni Frascà
- Giovanni Gambaro
- Giuseppe Derosa
- Gizella Petro
- Glenn Chertow
- Gnyandev Patel
- Godwin Simon
- Goga Vukotic
- Gopal Krishna
- Grace Aquitania
- Grace Lin
- Graham Hillis
- Graziano Di Cianni
- Grazyna Orlowska-Kowalik
- Grazyna Popenda
- Greene T.
- Greg Fulcher
- Gregorio Obrador
- Gregorio Obrador Vera
- Grit Faulmann
- Guadalupe Morales Franco
- Guillermo Fragale
- Guixia Wang
- Gulam Latiff
- Gustavo Cristian Greloni
- Guy Chouinard
- Gyongyi Csecsei
- Gyorgy Paragh
- Halyna Tomashkevych
- Hans Prozesky
- Harpreet Bajaj
- Hasnain Khandwala
- Hector Rodriguez
- Heerspink H. J. L.
- Helena Oosthuizen
- Hendrik Nortje
- Henry Watson
- Hermann Haller
- Hernan Finkelstein
- Hernan Yupanqui
- Hiddo J L Heerspink
- Hiralal Maheshwari
- Hiroko Oishi
- Hiromi Aoki
- Hiromi Rodriguez Pattzi
- Hiroshi Kono
- Hitoshi Akiyama
- Holly Wang
- Hong Mao
- Hong Zhang
- Hongguang Zheng
- Hongli Lin
- Horacio Sessa
- Hugo Colombo
- Hugo Laviada Molina
- Hugo Roberto Kurtz Lisboa
- Humberto Pavon
- Hyuk-Sang Kwon
- Iain MacDougall
- Ian Fraser
- Idalia Acosta
- Ildiko Halmagyi
- In-Kyung Jeong
- Ines Bartolacci
- Ingrid Abrahamsen
- Ingrid Buganova
- Inna Kolesnyk
- Ioana Emilia Ferariu
- Irene Noronha
- Irina Glinkina
- Irina Osipova
- Iryna Dudar
- Isabel Erika Rucker Joerg
- Isabel Garcia
- Isam Marar
- Israel Hartman
- Iuliia Komisarenko
- Ivan Fushtey
- Ivan Ory
- Ivan Rychlik
- Ivan Rychlík
- Ivan Smirnov
- Ivan Topchii
- Ivan Villegas
- Iveta Smatanova
- Jaco Jurgens
- Jakkidi Reddy
- Jamal Hammoud
- James Conway
- James Januzzi
- James Welker
- Jan Culak
- Jana Babikova
- Jana Belobradkova
- Jana Dzuponova
- Janos Mucsi
- Jardine M. J.
- Jason Gaglia
- Javier Narvarte
- Javier Nieto Iglesias
- Jayameena Peringat
- Jayant Kumar
- Jean Carlo Tibes Hachmann
- Jean Welsh
- Jean-Pierre Fauvel
- Jeevren Reddy
- Jeffrey Kropp
- Jeffrey Stephens
- Jeimeen Agra
- Jelena Ignjatovic
- Jesus Cuadrado
- Jesus Egido de Los Rios
- Jian Liu
- Jiao Sun
- Jinkui Yang
- Jiri Lastuvka
- Jiri Pumprla
- Joaquin Pablo Gonzalez
- Johannes Breedt
- John Amerena
- John Baker
- John Ervin
- John Evans
- John Lentz
- John Middleton
- John Padron
- John Sensenbrenner
- John Updegrove
- John Wakeling
- Jonay Pantoja Perez
- Jorge Archibaldo Glenny
- Jorge Avendano
- Jorge Ernesto Andres Diaz Ruiz
- Jorge Hector Resk
- Jorge Kusnir
- Jorge Mordujovich
- Jorgelina Sala
- Jose Antonio Sánchez Arenales
- Jose Chevaile Ramos
- Jose David Gomez Rangel
- Jose Esteban Jodar Gimeno
- Jose Francisco Kerr Saraiva
- Jose Hector Sanchez Mijangos
- Jose L Górriz
- Jose Luis Accini Mendoza
- Jose Ma Portoles Perez
- Jose Osvaldo Fretes
- Jose Ricardo Correa Rotter
- Joseph Abdallah
- Joseph Aiello
- Joseph Feuerstein
- Joseph O'Hare
- Joseph Proietto
- Josier Nisnisan
- José Vicente Sanchez Polo
- João Lindolfo Cunha Borges
- João Soares Felício
- Juan Alfredo Tamayo Y Orozco
- Juan Baas Cruz
- Juan Carlos Santos
- Juan Diego Higuera
- Juan Frias
- Juan Gonzalo Godoy Jorquera
- Juan Pablo Albisu
- Juan Pablo Moreira Diaz
- Juan Peralta Calcaneo
- Juan Rosas Guzman
- Juan Villagordoa Mesa
- JungEun Lee
- Kamal Abouglila
- Karel Peterka
- Karina Hufert
- Karlton Pettis
- Katalin Keltai
- Katalin Revesz
- Katarina Halciakova
- Katarina Lalic
- Kathy Nicholls
- Kati De Brouwer
- Kazuhiro Yanagida
- Kazunori Koyama
- Kazuyuki Mizuyama
- Kee Sing Ng
- Kenneth Cohen
- Kenneth Deck
- Kenneth Hershon
- Kenneth Liss
- Kenneth W Mahaffey
- Khalid Abdul Kadir
- Khurram Wadud
- Kim Travis
- Kiril Hristozov
- Kook-Hwan Oh
- Krisztian Kiss
- Kun Ho Yoon
- Lachezar Lozanov
- Lajos Major
- Lalaine Delos Santos
- Landman Lombard
- Larisha Pillay-Ramaya
- Larry Distiller
- Larysa Pererva
- Laszlo Deak
- Laszlo Konyves
- Laura Akright
- Laura Coffee
- Lawrence Distiller
- Lawrence Lehrner
- Lawrence Leiter
- Lech Lazuka
- Lee-Ming Chuang
- Lenka Dohnalova
- Leslie Spry
- Levin A.
- Li Yuan Lee
- Lidia Bermudez
- Ligia Petrica
- Lilia Beatriz Schiavi
- Liliana Monica Angelescu
- Liliia Zub
- Liliya Martynyuk
- Lin Sun
- Lincoln Chapin
- Linong Ji
- Lisa Rich
- Liudmila Kvitkova
- Lori Yost
- Luca Chiovato
- Luca De Nicola
- Luca Zanoli
- Lucas Rista
- Luciane Mônica Deboni
- Lucyna Hotlos
- Ludger Rose
- Luigi Gnudi
- Luis Alberto Ramirez Roca
- Luis Asmarats Mercadal
- Luis David Abraira Munoz
- Luis Enrique Herrera Jimenez
- Luis Fernando Flota Cervera
- Luis Henrique Canani
- Luis Hernando Garcia Ortiz
- Luis Isaias Juncos
- Luis Quesada-Suarez
- Luis Rodolfo Cartasegna
- Luis Valderrama Cometa
- Luis Venegas Carrillo
- Luiz Alberto Andreotti Turatti
- Luiza Despina Demian
- László Rosivall
- Ma Dovie Lallaine Ygpuara
- Mahaffey K. W.
- Manel Terns Riera
- Manish Saxena
- Manthi Hettiarachchi
- Manuel Muñoz Lopez Mendoza
- Manuel Muñoz Torres
- Manuela Schmidt
- Marc Rendell
- Marcel Twahirwa
- Marcelo Medina Fariña
- Marcora Mandreoli
- Marcus Gomes
- Margarita Temelkova
- Margarita Vejar
- Margit Mileder
- Margo Hudson
- Maria Antonia Munar Vila
- Maria Barnard
- Maria Cecilia Cantero
- Maria Florencia Fernandez
- Maria Isabel Klyver
- Maria Jaime
- Maria Rosa Ulla
- Maria Teresa Zanella
- Maria Valdez
- Marializa Bernardo
- Marianna Zsom
- Mario Alberto Berli
- Mario Burgos Soto
- Mark Davies
- Mark Vannorsdall
- Mark Warren
- Markus Faghih
- Marsha Tolentino
- Marta Dominquez Lopez
- Marta Molnar
- Martin Lukac
- Martin Valis
- Martine Destree
- Mary Anne Lim-Abrahan
- Mary Lawrence
- Mary Seeber
- Maryna Vlasenko
- María Alicia Fernández Montenegro
- María Angustias Quesada Simón
- Masahiko Takai
- Masahiro Koizumi
- Masakiyo Wakasugi
- Masayo Yamada
- Mastura Ismail
- Matthew Abramowitz
- Matthew Beacom
- Meg J Jardine
- Meg Jardine
- Meininger G.
- Melchor Alpizar Salazar
- Melemadathil Sreelatha
- Merce Perez Vera
- Mercedes Velo Plaza
- Michael Oliver
- Michael Robinson
- Michael Shanik
- Michael Thompson
- Michael Williams
- Michal Nowicki
- Michał Nowicki
- Michelle Zaniewski-Singh
- Mick Kumwenda
- Miguel Nazzer Hissa
- Migues Angel Reyes Rosano
- Mihaela Biscoveanu
- Mihaela-Magdalena Busegeanu
- Mihaly Dudas
- Milan Gupta
- Min Jeong Kwon
- Minara Shamkhalova
- Minghui Zhao
- Miodrag Djordjevic
- Mircea Munteanu
- Mitsuru Tsujimoto
- Mohamed El-Shahawy
- Mohamed Mookadam
- Mohamed Railey
- Mohamed Sekkarie
- Mohanram Narayanan
- Mohd Daud Che Yusof
- Mohsen El Kossi
- Mona Wahba
- Monica Alexandra Terront Lozano
- Monika Dhillon
- Moogali Arvind
- Moon-Kyu Lee
- Moon-Suk Nam
- Moustafa Moustafa
- Muhammad Shakeel
- Mukesh Joshi
- Mykola Kolesnyk
- Márcio Antônio Pereira
- Nadia Zalunardo
- Nadiya Tryshchuk
- Nan Chen
- Narayan Prasad
- Naresh Aggarwal
- Natalia Malaver
- Nataliia Pashkovska
- Natarajan Gopalakrishnan
- Navdeep Tangri
- Naveen Atray
- Neal B.
- Nebojsa Lalic
- Neil Kumar
- Nelson Kopyt
- Nelson Rodriguez Papini
- Nestor Horacio Garcia
- Ngai Wah Cheung
- Nicolae Hancu
- Nicole Li
- Nik Nur Fatnoon Nik Ahmad
- Nina Patel
- Nizar Daboul
- Noble Gracious
- Nomangesi Ngcakani
- Nonna Kravchun
- Nora Marchetta
- Norman Muirhead
- Norsiah Ali
- Oleg Legun
- Oleg Nagibovich
- Oleg Uriasyev
- Oleksandr Golovchenko
- Oleksandr Samoylov
- Oleksii Korzh
- Olga Barbarash
- Olga Barna
- Olga Barysheva
- Olga Benusova
- Olga Godlevska
- Olga Gyrina
- Olga Sazonova
- Olivert Gomez
- Oomman Abraham
- Osamu Tomonaga
- Oscar Tarsicio Moreno Loza
- Osvaldo Brusco
- Pablo Antonio Novoa
- Pablo Mele
- Pablo Raffaele
- Pablo Serrano Sanson
- Paranthaman Vengadasalam
- Patricia Del Carmen Gonzalez Colaso
- Patrick English
- Patrick Parfrey
- Paul Ainsworth
- Paul Frenk Baron
- Paul Nixon
- Paul Noonan
- Paul Rheeder
- Paulina Virginia Lanchiotti
- Pavel Weiner
- Peak Mann Mah
- Pedro Calella
- Pedro de Souza
- Pedro Velasquez-Mieyer
- Peggy Barnhill
- Peggy Lin
- Pere Alvarez Garcia
- Perkovic V.
- Peter Danos
- Peter Fulop
- Peter Van Buren
- Peter Winocour
- Petr Barton
- Philip Gorelick
- Philip Home
- Philip Nicol
- Philippe Zaoui
- Phyllis August
- Piermarco Piatti
- Pierre Gourdy
- Pierre-Jean Saulnier
- Pietro Castellino
- Pilar Trueba
- Ping Tu
- Pollock C.
- Prasanth Surampudi
- Pusadee Suchinda
- Qinkai Chen
- Rachel Bregman
- Radica Alicic
- Radu Jacob
- Rafael Simo Canonge
- Raied Abdullah
- Rajendran Alappan
- Rajiv Agarwal
- Rajiv Ranjan
- Raju Sree Bhushan
- Rakesh Gulati
- Rakhi Khanna
- Rallabhandi Sankaram
- Raman Purighalla
- Ramesh Chandra Vyasam
- Ramesh Thimmaiah
- Ramon Berenguer
- Ramon Moreda
- Rangel Rangelov
- Rao K Satyanarayana
- Ravendran Govender
- Ravi Sarin
- Reddy Sreedhar
- Reginald Parker
- Rehan Symonds
- Reinhold Jerwan-Keim
- Remi Rabasa-Lhoret
- Renan Montenegro Junior
- Renata Bijata-Bronisz
- Rhea Severina Comia
- Rhonda Bentley-Lewis
- Riad Darwish
- Ricardo Alfonso Leon de la Fuente
- Ricardo Dario Dran
- Ricardo Rosero
- Riccardo Bonadonna
- Richard Ferkl
- Richard Kovar
- Richard Lindley
- Richard Orozco Castellanos
- Richard Solomon
- Robert Busch
- Robert Cohen
- Robert Schreiman
- Robert Takacs
- Robert Walker
- Roberto Abrão Raduan
- Roberto Jorge da Silva Franco
- Roberto Pecoits Filho
- Roberto Pecoits-Filho
- Roberto Simões de Almeida
- Roberto Trevisan
- Rodica-Ioana Avram
- Rodolfo Andres Ahuad Guerrero
- Rohana Abdul Ghani
- Rohit Pankhaniya
- Rolando Zamarripa Escobedo
- Ronald Goldenberg
- Ronald Harris
- Ronald Watts
- Ronaldo Arturo Gonzalez Orellana
- Ronan Roussel
- Ronnie Aronson
- Rosa Isela Luna Ceballos
- Rosângela Milagres
- Ruben Dario Vargas Alonso
- Rury Holman
- Russell Scott
- Sacha De Serres
- Sahay Manisha
- Saiful Shahrizal Bin Shudim
- Sailaja Ventrapragada
- Salah Abusnana
- Salvatore De Cosmo
- Sam Henein
- Sam Philip
- Samuel Cohen
- Samuel Mujica Trenche
- Samy Hadjadj
- Sandor Keresztesi
- Sandor Vangel
- Sandra Berenice Saaveddra Sanchez
- Sanjeev Rastogi
- Sara Jaffer
- Sarah Olelewe
- Satoshi Ota
- Satu Pesickova
- Scott Kasner
- Secundino Cigarran Guldris
- Senan Sultan
- Serge Cournoyer
- Sergei Nedogoda
- Sergey Vorobyev
- Sergio Saul Irizar Santana
- Shahabul Arfeen
- Shahnaz Shahinfar
- Shang-Jyh Hwang
- Shelley Williams
- Shenaz Ramtoola
- Shenglian Gan
- Sherry Sussman
- Shizuo Kajiyama
- Shozo Miyauchi
- Silvia Ines Orio
- Silvia Nicolai
- Simon Davies
- Simon Roger
- Simon Young
- Sin Gon Kim
- Singhan Krishnan
- Sini George
- Slobodan Antic
- Sohan Dua
- Sonia Hermida
- Soo Kun Lim
- Sophie Borot
- Souhila Ounadjela
- Sreedhar Mandayam
- Srikanth Bellary
- Stanislav Zemek
- Stanislaw Mazur
- Stefan Dimitrov
- Stephan Maxeiner
- Stephen Grubb
- Stephen Smith
- Steven Fishbane
- Stuart Handelsman
- Suely Keiko Kohara
- Sun Kim
- Sun-Hee Park
- Sunil Sheth
- Susumu Kashine
- Svetlana Goykhman
- Svitlana D Bilyk
- Swee Win Lam
- Sylvia Rosas
- Sylvia Shaw
- Szilard Vasas
- Sérgio Alberto Cunha Vêncio
- Sérgio Yamada
- Tadashi Iitsuka
- Takamoto Kodera
- Takashi Wada
- Takayuki Watanabe
- Tamara Malek Marin
- Tamas Oroszlan
- Tara Chang
- Tareq Nassar
- Tarissa Beatrice Zanata Petry
- Tatiana Koroleva
- Tatiana Morugova
- Tatiana Raskina
- Tatyana Zykova
- Te-Lin Hsia
- Terue Sakakibara
- Tetiana Zlova
- Tetsuji Niiya
- Tetyana Pertseva
- Tiago Schuch
- Timothy Hall
- Tom Christensen
- Tom Greene
- Tomas Drasnar
- Tomas Smith Casabella
- Tonatiu Diaz Escalante
- Toshihiko Yanase
- Toshio Kawada
- Vadym Vizir
- Vanassa Ratnasingam
- Venessa Tsang
- Venkata Behara
- Vera Klokocnikova
- Vera Krane
- Veronica Anghel
- Veselka Genadieva
- Vesna Popovic-Radinovic
- Viacheslav Marasaev
- Victor Commendatore
- Victor Saavedra Gajardo
- Vijayaraman Arutchelvam
- Viktor Margaritov
- Viktor Zaviriukha
- Viktoria Andreeva
- Vimladhevi Govender
- Vincent Pichette
- Vincent Woo
- Vira Tseluyko
- Virginia Esther Visco
- Vivek Sood
- Vivekan Jha
- Vladimir Dobronravov
- Vladimir Khirmanov
- Vladimir Tesar
- Vlado Perkovic
- Volker Burst
- Volodymyr Botsyurko
- Walter Guillermo Douthat
- Walter Pharr
- Wasim Hanif
- Wataru Yumita
- Wayne H-H Sheu
- Wayne Turner
- Wei Yen Kong
- Weihong Song
- Weiping Lu
- Wendy Lane
- Wenge Li
- Wheeler D. C.
- Wladmir Saporito
- Xuemei Li
- Xueqing Yu
- Yamil Canaan
- Yan Ren
- Yannick Le Meur
- Yaozhong Kong
- Yasuro Kumeda
- Yasushi Wakida
- Yavin Y.
- Yeong Hoon Kim
- Yevgeniya Svyshchenko
- Young Min Cho
- Yulia Samoylova
- Yung-Chuan Lu
- Yuriy Mostovoy
- Yuriy Shwartz
- Yvette Ethel Yap
- Zaynab Abejuela
- Zdravko Kamenov
- Zeid Khitan
- Zhang H.
- Zinman B.
- Zishan Ali
- Zuzana Ochodnicka
- Ângela Regina Nazario Sabbag
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2019
- Field of study
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
Multidifferential study of identified charged hadron distributions in Z-tagged jets in proton-proton collisions at s=13 TeV
- Author
- Aaij Roel
- Abdelmotteleb Ahmed Sameh Wagih
- Abellan Beteta Carlos
- Abudinén Fernando Jesus
- Ackernley Thomas
- Adeva Bernardo
- Adinolfi Marco
- Afsharnia Hossein
- Agapopoulou Christina
- Aidala Christine Angela
- Aiola Salvatore
- Ajaltouni Ziad
- Akar Simon
- Akiba Kazuyoshi
- Albrecht Johannes
- Alessio Federico
- Alexander Michael
- Alfonso Albero Alejandro
- Aliouche Zakariya
- Alvarez Cartelle Paula
- Amalric Renaud
- Amato Sandra
- Amey Jake Lewis
- Amhis Yasmine
- An Liupan
- Anderlini Lucio
- Andersson Martin
- Andreianov Aleksei
- Andreotti Mirco
- Andreou Dimitra
- Ao Dong
- Archilli Flavio
- Artamonov Alexander
- Artuso Marina
- Aslanides Elie
- Atzeni Michele
- Audurier Benjamin
- Bachmann Sebastian
- Bachmayer Marie
- Back John
- Bailly-Reyre Aurelien
- Baladron Rodriguez Pablo
- Balagura Vladislav
- Baldini Wander
- Baptista de Souza Leite Juan
- Barbetti Matteo
- Barlow Roger
- Barsuk Sergey
- Barter William
- Bartolini Matteo
- Baryshnikov Fedor
- Basels Jan-Marc
- Bassi Giovanni
- Batsukh Baasansuren
- Battig Alexander
- Bay Aurelio
- Beck Anja
- Becker Maik
- Bedeschi Franco
- Bediaga Ignacio
- Beiter Andrew
- Belavin Vladislav
- Belin Samuel
- Bellee Violaine
- Belous Konstantin
- Belov Ilia
- Belyaev Ivan
- Ben-Haim Eli
- Benane Gaya
- Bencivenni Giovanni
- Berezhnoy Alexander
- Bernet Roland
- Berninghoff Daniel
- Bernstein Harris Conan
- Bertella Claudia
- Bertolin Alessandro
- Betancourt Christopher
- Betti Federico
- Bezshyiko Iaroslava
- Bhasin Srishti
- Bhom Jihyun
- Bian Lingzhu
- Bieker Martin Stefan
- Biesuz Nicolo Vladi
- Bifani Simone
- Billoir Pierre
- Biolchini Alice
- Birch Matthew
- Bishop Fionn Caitlin Ros
- Bitadze Alexander
- Bizzeti Andrea
- Blago Michele Piero
- Blake Thomas
- Blanc Frederic
- Blusk Steven
- Bobulska Dana
- Boelhauve Julian Alexander
- Boente Garcia Oscar
- Boettcher Thomas
- Boldyrev Alexey
- Bolognani Carolina
- Bondar Nikolay
- Borghi Silvia
- Borsato Martino
- Borsuk Jozef Tomasz
- Bouchiba Sonia Amina
- Bowcock Themistocles
- Boyer Alexandre
- Bozzi Concezio
- Bradley Matthew John
- Braun Svende
- Brea Rodriguez Alexandre
- Brodzicka Jolanta
- Brossa Gonzalo Arnau
- Brundu Davide
- Buonaura Annarita
- Buonincontri Laura
- Burke Aodhan Tomas
- Burr Christopher
- Bursche Albert
- Butkevich Anatoly
- Butter Jordy Sebastiaan
- Buytaert Jan
- Byczynski Wiktor
- Cadeddu Sandro
- Cai Hao
- Calabrese Roberto
- Calefice Lukas
- Cali Stefano
- Calladine Ryan
- Calvi Marta
- Calvo Gomez Miriam
- Campana Pierluigi
- Campora Perez Daniel Hugo
- Campoverde Quezada Angel Fernando
- Capelli Simone
- Capriotti Lorenzo
- Carbone Angelo
- Carboni Giovanni
- Cardinale Roberta
- Cardini Alessandro
- Carli Ina
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- Carus Leon David
- Casais Vidal Adrian
- Caspary Rowina
- Casse Gianluigi
- Cattaneo Marco
- Cavallero Giovanni
- Cavallini Viola
- Celani Sara
- Cerasoli Jacopo
- Cervenkov Daniel
- Chadwick Abbie Jane
- Chapman Matthew George
- Charles Matthew
- Charpentier Philippe
- Chavez Barajas Carlos Alberto
- Chefdeville Maximilien
- Chen Chen
- Chen Shanzhen
- Chernov Aleksei
- Chernyshenko Serhii
- Chobanova Veronika
- Cholak Serhii
- Chrzaszcz Marcin
- Chubykin Aleksei
- Chulikov Vladimir
- Ciambrone Paolo
- Cicala Maria Flavia
- Cid Vidal Xabier
- Ciezarek Gregory
- Clarke Peter
- Clemencic Marco
- Cliff Harry
- Closier Joel
- Cobbledick John Leslie
- Coco Victor
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- Cogan Julien
- Cogneras Eric
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- Colombo Tommaso
- Congedo Liliana
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- Corredoira Imanol
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- Couturier Benjamin
- Craik Daniel Charles
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- Cruz Torres Melissa Maria
- Currie Robert
- d'Ambrosio Carmelo
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- da Silva Cesar Luiz
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- Dai Lingyun
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- Davies Jonathan Edward
- Davis Adam
- de Aguiar Francisco Oscar
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- de Lucia Erika
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- de Paula Leandro
- de Serio Marilisa
- de Simone Dario
- de Simone Patrizia
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- de Vries Jacco
- Dean Cameron Thomas
- Debernardis Francesco
- Decamp Daniel
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- del Buono Luigi
- Delaney Blaise
- Dembinski Hans Peter
- Denysenko Vadym
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- Gibson Valerie
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- Greeven Lex Marinus
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- Jost Beat
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- Keizer Floris
- Keller Dustin Michael
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- Kleijne Nico
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- Shen Zhihong
- Sheng Shuqi
- Shevchenko Vladimir
- Shi Boan
- Shields Edward Brendan
- Shimizu Yuya
- Shmanin Evgenii
- Shupperd Joseph David
- Siddi Benedetto Gianluca
- Silva Coutinho Rafael
- Simi Gabriele
- Simone Saverio
- Singla Minni
- Skidmore Nicola
- Skuza Raphael
- Skwarnicki Tomasz
- Slater Mark
- Smallwood Jennifer Clare
- Smeaton John Gordon
- Smith Eluned
- Smith Krista Lizbeth
- Smith Mark
- Snoch Aleksandra
- Soares Lavra Lais
- Sokoloff Michael
- Soler Paul
- Solomin Anatoly
- Solovev Aleksandr
- Solovyev Ivan
- Souza de Almeida Felipe Luan
- Souza de Paula Bruno
- Spaan Bernhard
- Spadaro Norella Elisabetta
- Spiridenkov Eduard
- Spradlin Patrick
- Sriskaran Viros
- Stagni Federico
- Stahl Marian
- Stahl Sascha
- Stanislaus Seophine
- Stein Eloise Noelle
- Steinkamp Olaf
- Stenyakin Oleg
- Stevens Holger
- Stone Sheldon
- Strekalina Daria
- Suljik Fidan
- Sun Jiayin
- Sun Liang
- Sun Yipeng
- Svihra Peter
- Swallow Paul Nathaniel
- Swientek Krzysztof
- Szabelski Adam
- Szumlak Tomasz
- Szymanski Maciej Pawel
- t'Jampens Stephane
- Tan Yinghua
- Taneja Shantam
- Tanner Alastair Roger
- Tat Martin Duy
- Terentev Aleksandr
- Teubert Frederic
- Thomas Eric
- Thompson Daniel James David
- Thomson Kayleigh Anne
- Tilquin Hanae
- Tisserand Vincent
- Tobin Mark
- Tomassetti Luca
- Tonani Giorgia
- Tong Xingyu
- Torres Machado Diego
- Tou da Yu
- Trifonova Ekaterina
- Trilov Stoyan Miroslavov
- Trippl Carina
- Tuci Giulia
- Tully Alison
- Tuning Niels
- Ukleja Artur
- Unverzagt Daniel Joachim
- Ursov Eduard
- Usachov Andrii
- Ustyuzhanin Andrey
- Uwer Ulrich
- Vagner Alexander
- Vagnoni Vincenzo
- Valassi Andrea
- Valenti Giovanni
- Valls Canudas Nuria
- van Beuzekom Martinus
- van Dijk Maarten
- van Hecke Hubert
- van Herwijnen Eric
- van Hulse Charlotte Barbara
- van Veghel Maarten
- Vazquez Gomez Ricardo
- Vazquez Regueiro Pablo
- Vecchi Stefania
- Velthuis Jaap
- Veltri Michele
- Venkateswaran Aravindhan
- Veronesi Michele
- Vesterinen Mika
- Vieira Daniel
- Vieites Diaz Maria
- Vilasis-Cardona Xavier
- Vilella Figueras Eva
- Villa Andrea
- Vincent Pascal
- Volle Felicia Carolin
- Vom Bruch Dorothea
- Vorobyev Alexey
- Vorobyev Vitaly
- Voropaev Nikolai
- Vos Kimberley
- Vrahas Constantinos
- Vázquez Sierra Carlos
- Waldi Roland
- Walsh John
- Wan Guanyue
- Wang Chishuai
- Wang Jialu
- Wang Jianchun
- Wang Jianqiao
- Wang Jike
- Wang Mengzhen
- Wang Rui
- Wang Xiaolin
- Wang Yilong
- Wang Zhenzi
- Wang Zirui
- Wang Ziyi
- Ward Jake Alexander
- Watson Nigel
- Websdale David
- Wei Yajing
- Weisser Constantin
- Westhenry Benedict Donald C
- White Dylan Jaide
- Whitehead Mark
- Wiederhold Aidan Richard
- Wiedner Dirk
- Wilkinson Guy
- Wilkinson Michael K
- Williams Ifan
- Williams Mark Richard James
- Williams Mike
- Williams Richard Morgan
- Wilson Fergus
- Wislicki Wojciech
- Witek Mariusz
- Witola Lukas
- Wong Cheuk Ping
- Wormser Guy
- Wotton Stephen
- Wu Hangyi
- Wyllie Kenneth
- Xiang Zhiyu
- Xiao Dong
- Xie Yuehong
- Xu Ao
- Xu Jingyi
- Xu Li
- Xu Liangjun
- Xu Menglin
- Xu Qingnian
- Xu Zehua
- Xu Zhihao
- Yang Di
- Yang Shuangli
- Yang Youhua
- Yang Zhenwei
- Yang Zishuo
- Yeomans Lauren Emma
- Yin Hang
- Yu Jiesheng
- Yuan Xuhao
- Zaffaroni Ettore
- Zavertyaev Mikhail
- Zdybal Milosz
- Zenaiev Oleksandr
- Zeng Ming
- Zhang Chenjia
- Zhang Dongliang
- Zhang Liming
- Zhang Shulei
- Zhang Shunan
- Zhang Yanxi
- Zhang Yu
- Zharkova Alina
- Zhelezov Alexey
- Zheng Yangheng
- Zhou Tianwen
- Zhou Xiaokang
- Zhou Yixiong
- Zhovkovska Valeriia
- Zhu Xianglei
- Zhu Xiaoyu
- Zhu Zhanwen
- Zhukov Valery
- Zou Quan
- Zucchelli Stefano
- Zuliani Davide
- Zunica Gianluca
- Publication venue
- Publication date
- 24/08/2022
- Field of study
Jet fragmentation functions are measured for the first time in proton-proton
collisions for charged pions, kaons, and protons within jets recoiling against
a Z boson. The charged-hadron distributions are studied longitudinally and
transversely to the jet direction for jets with transverse momentum 20 <pT<100 GeV and in the pseudorapidity range 2.5<η<4. The
data sample was collected with the LHCb experiment at a center-of-mass energy
of 13 TeV, corresponding to an integrated luminosity of 1.64 fb−1. Triple
differential distributions as a function of the hadron longitudinal momentum
fraction, hadron transverse momentum, and jet transverse momentum are also
measured for the first time. This helps constrain transverse-momentum-dependent
fragmentation functions. Differences in the shapes and magnitudes of the
measured distributions for the different hadron species provide insights into
the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any
supplementary material and additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb
public pages
Study of the B−→Λc+Λˉc−K− decay
- Author
- Aaij Roel
- Abdelmotteleb Ahmed Sameh Wagih
- Abellan Beteta Carlos
- Abudinén Fernando Jesus
- Ackernley Thomas
- Adeva Bernardo
- Adinolfi Marco
- Adlarson Patrik Harri
- Afsharnia Hossein
- Agapopoulou Christina
- Aidala Christine Angela
- Aiola Salvatore
- Ajaltouni Ziad
- Akar Simon
- Akiba Kazuyoshi
- Albrecht Johannes
- Alessio Federico
- Alexander Michael
- Alfonso Albero Alejandro
- Aliouche Zakariya
- Alvarez Cartelle Paula
- Amalric Renaud
- Amato Sandra
- Amey Jake Lewis
- Amhis Yasmine
- An Liupan
- Anderlini Lucio
- Andersson Martin
- Andreianov Aleksei
- Andreotti Mirco
- Andreou Dimitra
- Ao Dong
- Archilli Flavio
- Artamonov Alexander
- Artuso Marina
- Aslanides Elie
- Atzeni Michele
- Audurier Benjamin
- Bachmann Sebastian
- Bachmayer Marie
- Back John
- Bailly-Reyre Aurelien
- Baladron Rodriguez Pablo
- Balagura Vladislav
- Baldini Wander
- Baptista de Souza Leite Juan
- Barbetti Matteo
- Barlow Roger
- Barsuk Sergey
- Barter William
- Bartolini Matteo
- Baryshnikov Fedor
- Basels Jan-Marc
- Bassi Giovanni
- Batsukh Baasansuren
- Battig Alexander
- Bay Aurelio
- Beck Anja
- Becker Maik
- Bedeschi Franco
- Bediaga Ignacio
- Beiter Andrew
- Belavin Vladislav
- Belin Samuel
- Bellee Violaine
- Belous Konstantin
- Belov Ilia
- Belyaev Ivan
- Ben-Haim Eli
- Benane Gaya
- Bencivenni Giovanni
- Berezhnoy Alexander
- Bernet Andres Sergi
- Bernet Roland
- Berninghoff Daniel
- Bernstein Harris Conan
- Bertella Claudia
- Bertolin Alessandro
- Betancourt Christopher
- Betti Federico
- Bezshyiko Iaroslava
- Bhasin Srishti
- Bhom Jihyun
- Bian Lingzhu
- Bieker Martin Stefan
- Biesuz Nicolo Vladi
- Bifani Simone
- Billoir Pierre
- Biolchini Alice
- Birch Matthew
- Bishop Fionn Caitlin Ros
- Bitadze Alexander
- Bizzeti Andrea
- Blago Michele Piero
- Blake Thomas
- Blanc Frederic
- Blank Jonah Evan
- Blusk Steven
- Bobulska Dana
- Boelhauve Julian Alexander
- Boente Garcia Oscar
- Boettcher Thomas
- Boldyrev Alexey
- Bolognani Carolina
- Bolzonella Riccardo
- Bondar Nikolay
- Borgato Federica
- Borghi Silvia
- Borsato Martino
- Borsuk Jozef Tomasz
- Bouchiba Sonia Amina
- Bowcock Themistocles
- Boyer Alexandre
- Bozzi Concezio
- Bradley Matthew John
- Braun Svende
- Brea Rodriguez Alexandre
- Brodzicka Jolanta
- Brossa Gonzalo Arnau
- Brown James David
- Brundu Davide
- Buonaura Annarita
- Buonincontri Laura
- Burke Aodhan Tomas
- Burr Christopher
- Bursche Albert
- Butkevich Anatoly
- Butter Jordy Sebastiaan
- Buytaert Jan
- Byczynski Wiktor
- Cadeddu Sandro
- Cai Hao
- Calabrese Roberto
- Calefice Lukas
- Cali Stefano
- Calladine Ryan
- Calvi Marta
- Calvo Gomez Miriam
- Campana Pierluigi
- Campora Perez Daniel Hugo
- Campoverde Quezada Angel Fernando
- Capelli Simone
- Capriotti Lorenzo
- Carbone Angelo
- Carboni Giovanni
- Cardinale Roberta
- Cardini Alessandro
- Carniti Paolo
- Carus Leon David
- Casais Vidal Adrian
- Caspary Rowina
- Casse Gianluigi
- Cattaneo Marco
- Cavallero Giovanni
- Cavallini Viola
- Celani Sara
- Cerasoli Jacopo
- Cervenkov Daniel
- Chadwick Abbie Jane
- Chapman Matthew George
- Charles Matthew
- Charpentier Philippe
- Chavez Barajas Carlos Alberto
- Chefdeville Maximilien
- Chen Chen
- Chen Shanzhen
- Chernov Aleksei
- Chernyshenko Serhii
- Chobanova Veronika
- Cholak Serhii
- Chrzaszcz Marcin
- Chubykin Aleksei
- Chulikov Vladimir
- Ciambrone Paolo
- Cicala Maria Flavia
- Cid Vidal Xabier
- Ciezarek Gregory
- Clarke Peter
- Clemencic Marco
- Cliff Harry
- Closier Joel
- Cobbledick John Leslie
- Coco Victor
- Coelho Joao A.B
- Cogan Julien
- Cogneras Eric
- Cojocariu Lucian
- Collins Paula
- Colombo Tommaso
- Congedo Liliana
- Contu Andrea
- Cooke Naomi
- Corredoira Imanol
- Corti Gloria
- Couturier Benjamin
- Craik Daniel Charles
- Cruz Torres Melissa Maria
- Currie Robert
- d'Ambrosio Carmelo
- d'Argent Philippe
- da Silva Cesar Luiz
- Dadabaev Shakhzod
- Dai Lingyun
- Dai Xinchen
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- Dalseno Jeremy
- Daniel Jessy
- Danilina Anna
- Davies Jonathan Edward
- Davis Adam
- de Aguiar Francisco Oscar
- de Boer Jan
- de Bruyn Kristof
- de Capua Stefano
- de Cian Michel
- de Freitas Carneiro da Graca Ulisses
- de Lucia Erika
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- de Paula Leandro
- de Serio Marilisa
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- de Vellis Fabio
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- Dean Cameron Thomas
- Debernardis Francesco
- Decamp Daniel
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- del Buono Luigi
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- Donohoe Amanda May
- Dordei Francesca
- dos Reis Alberto
- Douglas Lauren
- Downes Anthony Gavin
- Duda Piotr Jakub
- Dudek Maciej Wojciech
- Dufour Laurent
- Duk Viacheslav
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- Durham John Matthew
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- Egede Ulrik
- Egorychev Victor
- Eidelman Semen
- Eirea Orro Caetano
- Eisenhardt Stephan
- Ejopu Enoch
- Ek-In Surapat
- Eklund Lars
- Ely Scott
- Ene Alexandru
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- Escher Stephan
- Eschle Jonas Nathanael
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- Evans Timothy
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- Ferro-Luzzi Massimiliano
- Filippov Sergey
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- Fiorini Massimiliano
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- Fischer Kamil Leszek
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- Frank Markus
- Franzoso Edoardo
- Frau Giulia
- Frei Christoph
- Friday David Anthony
- Fu Jinlin
- Fuehring Quentin
- Fulghesu Tommaso
- Gabriel Emmy
- Galati Giuliana
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- Galli Domenico
- Gambetta Silvia
- Gan Yuyue
- Gandelman Miriam
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- Gao Yang
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- Garau Michela
- Garcia Martin Luis Miguel
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- Geertsema Robbert Erik
- Gerick David
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- Gersabeck Evelina
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- Gligorov Vladimir
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- Gomez Fernandez Sergio
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- Goncerz Mateusz
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- Gorelov Igor Vladimirovich
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- Grabowski Jascha Peter
- Grammatico Thomas
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- Graugés Eugeni
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- Grecu Alexandru Tudor
- Greeven Lex Marinus
- Grieser Nathan Allen
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- Guth Andreas
- Guz Yury
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- Göbel Carla
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- Hadavizadeh Thomas
- Haefeli Guido
- Haen Christophe
- Haimberger Jakob
- Haines Susan
- Halewood-Leagas Tabitha
- Halvorsen Marius Maehlum
- Hamilton Phoebe Meredith
- Hammerich Jan
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- Hansmann-Menzemer Stephanie
- Hao Lei
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- Henderson Riley Dylan Leslie
- Hennequin Arthur Marius
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- Henry Louis
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- Heuel Johannes
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- Hill Donal
- Hilton Martha
- Hollitt Sophie
- Horswill Joshua Ethan
- Hou Ruiwen
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- Hu Jiangqiao
- Hu Jifeng
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- Huang Wenqian
- Huang Xiaotao
- Hulsbergen Wouter
- Hunter Ross John
- Hushchyn Mikhail
- Hutchcroft David
- Ibis Philipp
- Idzik Marek
- Ilin Dmitrii
- Ilten Philip
- Inglessi Alexander
- Iniukhin Aleksandr
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- Ivshin Kuzma
- Jacobsson Richard
- Jage Hendrik
- Jaimes Elles Sergio Javier
- Jakobsen Sune
- Jans Eddy
- Jashal Brij Kishor
- Jawahery Abolhassan
- Jevtic Vukan
- Jiang Emily Kaiyin
- Jiang Xiaojie
- Jiang Yi
- John Malcolm
- Johnson Daniel
- Jones Christopher
- Jones Thomas Peter
- Jost Beat
- Jurik Nathan
- Juszczak Izabela
- Kandybei Sergii
- Kang Youen
- Karacson Matthias
- Karpenkov Dmitrii
- Karpov Maksim
- Kautz Jacob William
- Keizer Floris
- Keller Dustin Michael
- Kenzie Matthew
- Ketel Tjeerd
- Khanji Basem
- Kharisova Anastasiia
- Kholodenko Sergei
- Khreich Gaelle
- Kirn Thomas
- Kirsebom Veronica Soelund
- Kitouni Ouail
- Klaver Suzanne
- Kleijne Nico
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- Koliiev Serhii
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- Wormser Guy
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- Wu Jie
- Wyllie Kenneth
- Xiang Zhiyu
- Xiao Dong
- Xie Yuehong
- Xu Ao
- Xu Jingyi
- Xu Li
- Xu Liangjun
- Xu Menglin
- Xu Qingnian
- Xu Zehua
- Xu Zhihao
- Yang Di
- Yang Shuangli
- Yang Xueting
- Yang Youhua
- Yang Zhenwei
- Yang Zishuo
- Yeomans Lauren Emma
- Yeroshenko Vsevolod
- Yeung Ho Yin Dereck
- Yin Hang
- Yu Jiesheng
- Yuan Xuhao
- Zaffaroni Ettore
- Zavertyaev Mikhail
- Zdybal Milosz
- Zenaiev Oleksandr
- Zeng Ming
- Zhang Chenjia
- Zhang Dongliang
- Zhang Liming
- Zhang Shulei
- Zhang Shunan
- Zhang Yanxi
- Zhang Yu
- Zharkova Alina
- Zhelezov Alexey
- Zheng Yangheng
- Zhou Tianwen
- Zhou Xiaokang
- Zhou Yixiong
- Zhovkovska Valeriia
- Zhu Xianglei
- Zhu Xiaoyu
- Zhu Zhanwen
- Zhukov Valery
- Zou Quan
- Zucchelli Stefano
- Zuliani Davide
- Zunica Gianluca
- Publication venue
- Publication date
- 02/11/2022
- Field of study
The decay B−→Λc+Λˉc−K− is studied
in proton-proton collisions at a center-of-mass energy of s=13 TeV
using data corresponding to an integrated luminosity of 5 fb−1
collected by the LHCb experiment. In the Λc+K− system, the
Ξc(2930)0 state observed at the BaBar and Belle experiments is
resolved into two narrower states, Ξc(2923)0 and Ξc(2939)0,
whose masses and widths are measured to be m(Ξc(2923)0)=2924.5±0.4±1.1MeV,m(Ξc(2939)0)=2938.5±0.9±2.3MeV,Γ(Ξc(2923)0)=0004.8±0.9±1.5MeV,Γ(Ξc(2939)0)=0011.0±1.9±7.5MeV, where the first uncertainties are statistical and the second
systematic. The results are consistent with a previous LHCb measurement using a
prompt Λc+K− sample. Evidence of a new Ξc(2880)0
state is found with a local significance of 3.8σ, whose mass and width
are measured to be 2881.8±3.1±8.5MeV and 12.4±5.3±5.8MeV, respectively. In addition, evidence of a new decay mode
Ξc(2790)0→Λc+K− is found with a significance of
3.7σ. The relative branching fraction of B−→Λc+Λˉc−K− with respect to the B−→D+D−K−
decay is measured to be 2.36±0.11±0.22±0.25, where the first
uncertainty is statistical, the second systematic and the third originates from
the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb
public pages
Measurement of the ratios of branching fractions R(D∗) and R(D0)
- Author
- Aaij Roel
- Abdelmotteleb Ahmed Sameh Wagih
- Abellan Beteta Carlos
- Abudinén Fernando Jesus
- Ackernley Thomas
- Adeva Bernardo
- Adinolfi Marco
- Adlarson Patrik Harri
- Afsharnia Hossein
- Agapopoulou Christina
- Aidala Christine Angela
- Ajaltouni Ziad
- Akar Simon
- Akiba Kazuyoshi
- Albicocco Pietro
- Albrecht Johannes
- Alessio Federico
- Alexander Michael
- Alfonso Albero Alejandro
- Aliouche Zakariya
- Alvarez Cartelle Paula
- Amalric Renaud
- Amato Sandra
- Amey Jake Lewis
- Amhis Yasmine
- An Liupan
- Anderlini Lucio
- Andersson Martin
- Andreianov Aleksei
- Andreotti Mirco
- Andreou Dimitra
- Ao Dong
- Archilli Flavio
- Artamonov Alexander
- Artuso Marina
- Aslanides Elie
- Atzeni Michele
- Audurier Benjamin
- Bachiller Perea Irene
- Bachmann Sebastian
- Bachmayer Marie
- Back John
- Bailly-Reyre Aurelien
- Baladron Rodriguez Pablo
- Balagura Vladislav
- Baldini Wander
- Baptista de Souza Leite Juan
- Barbetti Matteo
- Barlow Roger
- Barsuk Sergey
- Barter William
- Bartolini Matteo
- Baryshnikov Fedor
- Basels Jan-Marc
- Bassi Giovanni
- Batsukh Baasansuren
- Battig Alexander
- Bay Aurelio
- Beck Anja
- Becker Maik
- Bedeschi Franco
- Bediaga Ignacio
- Beiter Andrew
- Belin Samuel
- Bellee Violaine
- Belous Konstantin
- Belov Ilia
- Belyaev Ivan
- Ben-Haim Eli
- Benane Gaya
- Bencivenni Giovanni
- Berezhnoy Alexander
- Bernet Andres Sergi
- Bernet Roland
- Berninghoff Daniel
- Bernstein Harris Conan
- Bertella Claudia
- Bertolin Alessandro
- Betancourt Christopher
- Betti Federico
- Bezshyiko Iaroslava
- Bhasin Srishti
- Bhom Jihyun
- Bian Lingzhu
- Bieker Martin Stefan
- Biesuz Nicolo Vladi
- Billoir Pierre
- Biolchini Alice
- Birch Matthew
- Bishop Fionn Caitlin Ros
- Bitadze Alexander
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- Blake Thomas
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- Boente Garcia Oscar
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- Xu Menglin
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- Xu Zhihao
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- Yang Shuangli
- Yang Xueting
- Yang Youhua
- Yang Zhenwei
- Yang Zishuo
- Yeomans Lauren Emma
- Yeroshenko Vsevolod
- Yeung Ho Yin Dereck
- Yin Hang
- Yu Jiesheng
- Yuan Xuhao
- Zaffaroni Ettore
- Zavertyaev Mikhail
- Zdybal Milosz
- Zeng Ming
- Zhang Chenjia
- Zhang Dongliang
- Zhang Liming
- Zhang Shulei
- Zhang Shunan
- Zhang Yanxi
- Zhang Yu
- Zhao Ya
- Zharkova Alina
- Zhelezov Alexey
- Zheng Yangheng
- Zhou Tianwen
- Zhou Xiaokang
- Zhou Yixiong
- Zhovkovska Valeriia
- Zhu Xianglei
- Zhu Xiaoyu
- Zhu Zhanwen
- Zhukov Valery
- Zou Quan
- Zucchelli Stefano
- Zuliani Davide
- Zunica Gianluca
- Publication venue
- Publication date
- 01/01/2023
- Field of study
The ratios of branching fractions
R(D∗)≡B(Bˉ→D∗τ−νˉτ)/B(Bˉ→D∗μ−νˉμ) and R(D0)≡B(B−→D0τ−νˉτ)/B(B−→D0μ−νˉμ) are measured, assuming isospin symmetry, using a
sample of proton-proton collision data corresponding to 3.0 fb−1 of
integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The
tau lepton is identified in the decay mode
τ−→μ−ντνˉμ. The measured values are
R(D∗)=0.281±0.018±0.024 and
R(D0)=0.441±0.060±0.066, where the first uncertainty is
statistical and the second is systematic. The correlation between these
measurements is ρ=−0.43. Results are consistent with the current average
of these quantities and are at a combined 1.9 standard deviations from the
predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb
public pages
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
- Author
- Aase Handberg
- Abhijna R Ballal
- Abhimanyu Thakur
- Abuelreich Sarah
- Achille Anselmo
- Adam L Maddox
- Adityas Purnianto
- Adrian E Morelli
- Adrian L Harris
- Adriana F Paes Leme
- Adriana T Larregina
- Afrodité Németh
- Afsareen Bano
- Agnieszka Razim
- Agustin Enciso-Martinez
- Ahmed Ge Ibrahim
- Ahmed Somaida
- Aija Linē
- Ainhoa Alberro
- Ajay P Singh
- Akbar L Marzan
- Akhil Srivastava
- Akira Yokoi
- Al Charest
- Alain R Brisson
- Alan J Zimmerman
- Albano Cáceres-Verschae
- Aled Clayton
- Aleksandra Inic-Kanada
- Aleksei Tikhonov
- Alena Ivanova
- Alessandra Ciullo
- Alessandro Gori
- Alessio Noghero
- Alex J Rai
- Alexander Otahal
- Alexander R Ivanov
- Alexis G Murillo Carrasco
- Alice Gualerzi
- Alicia Galinsoga
- Alicia Llorente
- Aliosha I Figueroa-Valdés
- Alireza Fazeli
- Alissa M Weaver
- Alok Raghav
- Alvaro Compañ-Bertomeu
- Amanda Khoo
- Amanda Salviano-Silva
- Amandine Bonifay
- Amankeldi A Salybekov
- Amélie Nadeau
- Amin Zakeri
- Amirmohammad Nasiri Kenari
- Amit K Srivastava
- Amy A Baxter
- Amy C Kauffman
- Amy H Buck
- An Hendrix
- Ana C Torrecilhas
- Ana I Salazar-Puerta
- Ana O'Loghlen
- Anabela Cordeiro-da-Silva
- Anaïs Bécot
- Anders T Boysen
- Andras G Miklosi
- Andras Saftics
- András I Försönits
- Andre J van Wijnen
- Andrea Galisova
- Andrea Ridolfi
- Andrea Zendrini
- Andreas Möller
- Andreia M Silva
- Andreina Schoeberlein
- Andreu Matamoros-Angles
- Andrew Devitt
- Andrew F Hill
- Andrew Lai
- Andrew Rowland
- André Cronemberger-Andrade
- André Görgens
- Andries Zijlstra
- Angela M Zivkovic
- Angelica Ortiz
- Angelo Musicò
- Ann M Wehman
- Anna Antoniou
- Anna C Berardi
- Anna Cifuentes-Rius
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- Anna Koncz
- Anna M Schmid
- Anna Romolo
- Annaïg J Rozo
- Annalisa Radeghieri
- Annie Frelet-Barrand
- Annika Pfeiffer
- Anthony W Ferrante Jr
- Antje M Zickler
- Antoine Karoichan
- Antonella Bongiovanni
- Antonia Hufnagel
- Antonia Reale
- Antonio da Silva Novaes
- Antonio Marcilla
- Apolonija Bedina-Zavec
- Apurba Dev
- Asa M Wheelock
- Ashish Kumar
- Ashley E Russell
- Ashok K Shetty
- Asima Bhattacharyya
- Attila Oláh
- Augusto Zani
- Aurelia Rughetti
- Aurelio Lorico
- Aurélie Ledreux
- Avital A Rodal
- Ayesha Saleem
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- Áurea M Gabriel
- Bagabas Reem
- Baharak Hosseinkhani
- Bahnisikha Barman
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- Xiaomei Yan
- Xiaoqin Wang
- Xinhua Lei
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- Yasuo Inoshima
- Yi Wen
- Yinghong Zhou
- Yingtang Gao
- Yiyao Huang
- Yoel Sadovsky
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- Yongkang Yang
- Yonis Bare
- Yoon-Kyoung Cho
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- Yu Xiao
- Yuki Yamamoto
- Yumi Kumagai
- Yunjie Wu
- Yunxi Chen
- Yusuke Yamamoto
- Yusuke Yoshioka
- Yvan Courageux
- Yvonne Couch
- Zach Troyer
- Zendrini Andrea
- Zheng Lei
- Zheng Zhao
- Zijlstra Andries
- Zimmerman Alan J.
- Zivile Useckaite
- Zoltan Varga
- Zoltán Varga
- Zoltán Wiener
- Zucai Suo
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly
Finishing the euchromatic sequence of the human genome
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- Chi Cheng
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- Davies Robert
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- Davis Candi Mon\u27et
- Davis Cheryl
- Davis Clay
- Davis Jayne
- Davis John
- Davis Matthew
- Davy-Carroll Latarsha
- Dawoe Tenzin
- Dawson Elisabeth
- De Anda Claudia
- De Latorre Andrea
- Deadman Rebecca
- Dean Peter
- Dear Simon
- Dearden Frances
- DeArellano Kurt
- Deaven Larry I.
- Deaven Larry L.
- Deere Kerry
- DeGray Stewart
- Degusta David
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- Delgado Oliver
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- Dennis Janet
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- Denys Mirian
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- Desai Anu
- Detter John C.
- Devlin Laurie
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- Dhongsar Chemey
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- Ding Hao
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- Dinh Huyen H.
- Dixon Kami
- Do Long
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- Dockree Catherine
- Doddington Daniel
- Dodsworth Steven
- Doggett Norman
- Doggett Norman A.
- Dong Hui
- Dong Kimberly
- Dong Wei
- Dong Wei
- Dong Xiaojia
- Donlin Jeremy E.
- Dooley Kathy
- Dooling David
- Dorje Passang
- Dorjee Kunsang
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- Dorsett Victor
- Doucette-Stamm Lynn
- Douthwaite Karen J.
- Down Thomas
- Draper Heather
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- Duarte Suzanne
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- Dugan-Rocha Shannon
- Dunham Andrew
- Dunham Ian
- Dunn Adam M.
- Dunn Anne
- Dunn Matthew
- Dunwell Erin
- Dupes Alan
- Durbin Kenneth J.
- Durbin Richard
- Durham Jillian
- Dutta Ireena
- Dwyer Ruth
- Dyer Lauren
- Dziuda Darius
- Earnhardt Christopher D.
- Earthrowl Mark
- Eastham Emma
- Eastham Timothy
- Eaves Kristy A.
- Eckenberg Ralph
- Edgar Darren
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- Emelianenko Natalia
- Emery-Cohen Alexandra J.
- Endrizzi Matthew
- Engh Ger van den
- Engle David
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- Errington Helen
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- Eugene Craig S.
- Evans Gareth
- Evans John
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- Footman Simon
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- Fujiyama Asao
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- Fuller Liam
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- Garcia-Martinez Antonio
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- Garnes Jeffrey A.
- Garnett Jane
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- Gatland Leigh
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- Gibbs Ben
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- Gonzales Eidelyn
- Gonzalez Guillermo B.
- Gooderham April
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- Gordon Catherine
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- Gordon Seth
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- Gorvad Ann
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- Goyea Ernest
- Goyette Audra
- Grady Deborah I.
- Grady Michelle L.
- Grafham Darren
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- Grandbois Edward
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- Gray Bruce
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- Gribble Susan
- Griffith Jeffrey K.
- Griffiths Coline
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- Gui Qi
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- Hamilton Matt
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- Hammon Nancy
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- Hamza Khalid
- Han Guiqing
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- Hanak Vincent A.
- Hancock Julie
- Harbes Brandy A.
- Harding Adam
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- Hillyard Guy
- Hines Sandra
- Hinkins Russell
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- Hitchens Matthew Edward
- Ho Issac
- Ho Sara-Jane
- Hodgson Anne V.
- Hodgson David
- Hoffman Susan M.G.
- Hoffs Michael
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- Hubbard Timothy
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- Huckle Elizabeth
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- Hupman Matt
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- Hyde David
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- Idlebird Devincent G.
- Iliev Ilian
- Imbro Paula
- Imo Kelvin C.
- Inacio Nicole
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- Ince Michael
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- Inoue Shuuji
- Isak Amber
- Isherwood Judith
- Ishibashi Akiko
- Ishikawa Sabine K.
- Ishizaki Hinako
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- Jaklevic Joseph
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- Jia Jia
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- Jiang Lu
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- Kong Yi
- Korf Ian
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- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
- Kremitzki Colin
- Kremmidiotis Gabriel
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- Kronmiller Brent
- Kruchowski Scott S.
- Kube Michael
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- Lander Eric S.
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- Lewis Tammy
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- Lou Yunian
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- Lowenstein Michael G.
- Lowry Stephen
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- Mercado Iracema C.
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- Mesirov Jill P.
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- Nakato Eriko
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- Nandkeshwar Richard
- Nankervis Colin E.
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- Nash William
- Naylor Jerome
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- Nwokenkwo Stanley
- O\u27Donnell Paula
- O\u27Donovan Daniel
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- Obayashi Izumi
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- Zhang Yilin
- Zhang Ying
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- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
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- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Meta-analyses of genome-wide association studies for postpartum depression
- Author
- Aberg Karolina A.
- Adams Mark J.
- Andreassen Ole A.
- Anney Richard J.L.
- Bauer Anna E.
- Bigdeli Tim B.
- Byrne Enda M.
- Campbell Archie
- Campbell Megan L.
- Choi Karmel W.
- Corfield Elizabeth C.
- Davis Lea K.
- Dennis Cindy-Lee
- Di Florio Arianna
- Dubertret Caroline
- Feng Yen-Chen A.
- Frey Benicio N.
- Gloaguen Emilie
- Gordon-Smith Katherine
- Grigoriadis Sophie
- Guintivano Jerry
- Havdahl Alexandra
- Hubbard Leon
- Hucks Donald
- Jones Ian
- Jones Lisa A.
- Kennedy James L.
- Kiewa Jacqueline
- Koen Nastassja
- Krohn Holly
- Kunovac Kallak Theodora
- Li Yun
- Lu Yi
- Martin Nicholas G.
- McIntosh Andrew M.
- Meltzer-Brody Samantha
- Mihaescu Raluca
- Milgrom Jeannette
- Mullaert Jimmy
- Munk-Olsen Trine
- Mægbæk Merete L.
- Nyegaard Mette
- Oberlander Tim
- Olsen Catherine M.
- Pardiñas Antonio F.
- Perry Amy
- Peterson Roseann E.
- Raffield Laura M.
- Ramoz Nicolas
- Reichborn-Kjennerud Ted
- Robertson Blackmore Emma
- Rubinow David
- Sallis Hannah M.
- Saquib Nazmus
- Sealock Julia M.
- Shadyab Aladdin H.
- Skalkidou Alkistis
- Smoller Jordan W.
- Stein Dan J.
- Stowe Zachary N.
- Sullivan Patrick
- Taylor Valerie
- Tebeka Sarah
- Tesli Martin
- van den Oord Edwin J.C.G.
- Van Lieshout Ryan J.
- Vigod Simone N.
- Viktorin Alexander
- Walker Alicia
- Watson Hunna J.
- Werge Thomas
- Westlye Lars T.
- Whiteman David C.
- Wray Naomi
- Xiong Ying
- Yang Jessica M.K.
- Yao Shuyang
- Zar Heather J.
- Publication venue
- Psychiatry Online
- Publication date
- 18/10/2023
- Field of study
Objective:
Postpartum depression (PPD) is a common subtype of major depressive disorder (MDD) that is more heritable, yet is understudied in psychiatric genetics. The authors conducted meta-analyses of genome-wide association studies (GWASs) to investigate the genetic architecture of PPD.
Method:
Meta-analyses were conducted on 18 cohorts of European ancestry (17,339 PPD cases and 53,426 controls), one cohort of East Asian ancestry (975 cases and 3,780 controls), and one cohort of African ancestry (456 cases and 1,255 controls), totaling 18,770 PPD cases and 58,461 controls. Post-GWAS analyses included 1) single-nucleotide polymorphism (SNP)–based heritability (), 2) genetic correlations between PPD and other phenotypes, and 3) enrichment of the PPD GWAS findings in 27 human tissues and 265 cell types from the mouse central and peripheral nervous system.
Results:
No SNP achieved genome-wide significance in the European or the trans-ancestry meta-analyses. The of PPD was 0.14 (SE=0.02). Significant genetic correlations were estimated for PPD with MDD, bipolar disorder, anxiety disorders, posttraumatic stress disorder, insomnia, age at menarche, and polycystic ovary syndrome. Cell-type enrichment analyses implicate inhibitory neurons in the thalamus and cholinergic neurons within septal nuclei of the hypothalamus, a pattern that differs from MDD.
Conclusions:
While more samples are needed to reach genome-wide levels of significance, the results presented confirm PPD as a polygenic and heritable phenotype. There is also evidence that despite a high correlation with MDD, PPD may have unique genetic components. Cell enrichment results suggest GABAergic neurons, which converge on a common mechanism with the only medication approved by the U.S. Food and Drug Administration for PPD (brexanolone)
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