657 research outputs found
Robo-AO Kepler Survey IV: the effect of nearby stars on 3857 planetary candidate systems
We present the overall statistical results from the Robo-AO Kepler planetary
candidate survey, comprising of 3857 high-angular resolution observations of
planetary candidate systems with Robo-AO, an automated laser adaptive optics
system. These observations reveal previously unknown nearby stars blended with
the planetary candidate host star which alter the derived planetary radii or
may be the source of an astrophysical false positive transit signal. In the
first three papers in the survey, we detected 440 nearby stars around 3313
planetary candidate host stars. In this paper, we present observations of 532
planetary candidate host stars, detecting 94 companions around 88 stars; 84 of
these companions have not previously been observed in high-resolution. We also
report 50 more-widely-separated companions near 715 targets previously observed
by Robo-AO. We derive corrected planetary radius estimates for the 814
planetary candidates in systems with a detected nearby star. If planetary
candidates are equally likely to orbit the primary or secondary star, the
radius estimates for planetary candidates in systems with likely bound nearby
stars increase by a factor of 1.54, on average. We find that 35
previously-believed rocky planet candidates are likely not rocky due to the
presence of nearby stars. From the combined data sets from the complete Robo-AO
KOI survey, we find that 14.5\pm0.5% of planetary candidate hosts have a nearby
star with 4", while 1.2% have two nearby stars and 0.08% have three. We find
that 16% of Earth-sized, 13% of Neptune-sized, 14% of Saturn-sized, and 19% of
Jupiter-sized planet candidates have detected nearby stars.Comment: Accepted to the Astronomical Journa
Robo-AO Kepler Survey V: The effect of physically associated stellar companions on planetary systems
The Kepler light curves used to detect thousands of planetary candidates are
susceptible to dilution due to blending with previously unknown nearby stars.
With the automated laser adaptive optics instrument, Robo-AO, we have observed
620 nearby stars around 3857 planetary candidates host stars. Many of the
nearby stars, however, are not bound to the KOI. In this paper, we quantify the
association probability between each KOI and detected nearby stars through
several methods. Galactic stellar models and the observed stellar density are
used to estimate the number and properties of unbound stars. We estimate the
spectral type and distance to 145 KOIs with nearby stars using multi-band
observations from Robo-AO and Keck-AO. We find most nearby stars within 1" of a
Kepler planetary candidate are likely bound, in agreement with past studies. We
use likely bound stars as well as the precise stellar parameters from the
California Kepler Survey to search for correlations between stellar binarity
and planetary properties. No significant difference between the binarity
fraction of single and multiple planet systems is found, and planet hosting
stars follow similar binarity trends as field stars, many of which likely host
their own non-aligned planets. We find that hot Jupiters are ~4x more likely
than other planets to reside in a binary star system. We correct the radius
estimates of the planet candidates in characterized systems and find that for
likely bound systems, the estimated planetary candidate radii will increase on
average by a factor of 1.77, if either star is equally likely to host the
planet. We find that the planetary radius gap is robust to the impact of
dilution, and find an intriguing 95%-confidence discrepancy between the radius
distribution of small planets in single and binary systems.Comment: 19 pages, 12 figures, submitted to AAS Journal
Characterization of zebrafish polymerase iii promoters for the expression of short hairpin RNA interference molecules
RNA interference (RNAi) is a powerful, sequence specific, and long-lasting method of gene knockdown, and can be elicited by the expression of short-hairpin RNA (shRNA) molecules driven via polymerase III type 3 promoters from a DNA vector or transgene. To further develop RNAi as a tool in zebrafish, we have characterized the zebrafish U6 and H1 snRNA promoters and compared the efficiency of each of the promoters to express an shRNA and silence a reporter gene, relative to previously characterized U6 promoters from pufferfish, chicken, and mouse. Our results show that the zebrafish polymerase III promoters were capable of effective gene silencing in the zebrafish ZF4 cell line, but were ineffective in mammalian Vero cells. In contrast, mouse and chicken promoters were active in Vero but not ZF4 cells, highlighting the importance of homologous promoters to achieve effective silencing
Radiotherapy biobanking : current landscape, opportunities, challenges, and future aspirations
This work was supported by the National Cancer Research Institute (NCRI) Clinical and Translational Radiotherapy Research Working Group (CTRad), which was established in 2009 by six of the NCRI's funding partners. We gratefully acknowledge Carolyn Chan and Julie Stock (NCRI) for their assistance in collecting the responses to the questionnaire sent to CTRad membership. Open Access via the Wiley OA AgreementPeer reviewedPublisher PD
Evidence of a large seasonal coastal upwelling system along the southern shelf of Australia
2000 FLORIDA AVE NW, WASHINGTON, USA, DC,
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An Unbiased Survey of 500 Nearby Stars for Debris Disks: A JCMT Legacy Program
We present the scientific motivation and observing plan for an upcoming
detection survey for debris disks using the James Clerk Maxwell Telescope. The
SCUBA-2 Unbiased Nearby Stars (SUNS) Survey will observe 500 nearby main
sequence and sub-giant stars (100 of each of the A, F, G, K and M spectral
classes) to the 850 micron extragalactic confusion limit to search for evidence
of submillimeter excess, an indication of circumstellar material. The survey
distance boundaries are 8.6, 16.5, 22, 25 and 45 pc for M, K, G, F and A stars,
respectively, and all targets lie between the declinations of -40 deg to 80
deg. In this survey, no star will be rejected based on its inherent properties:
binarity, presence of planetary companions, spectral type or age. This will be
the first unbiased survey for debris disks since IRAS. We expect to detect ~125
debris disks, including ~50 cold disks not detectable in current shorter
wavelength surveys. A substantial amount of complementary data will be required
to constrain the temperatures and masses of discovered disks. High resolution
studies will likely be required to resolve many of the disks. Therefore, these
systems will be the focus of future observational studies using a variety of
observatories to characterize their physical properties. For non-detected
systems, this survey will set constraints (upper limits) on the amount of
circumstellar dust, of typically 200 times the Kuiper Belt mass, but as low as
10 times the Kuiper Belt mass for the nearest stars in the sample
(approximately 2 pc).Comment: 11 pages, 7 figures (3 color), accepted by the Publications of the
Astronomical Society of the Pacifi
Integrating local environmental observations and remote sensing to better understand the life cycle of a thermokarst lake in Arctic Alaska
On 29 June 2022, local observers reported the drainage of a 0.5 ha lake near Qikiqtaġruk (Kotzebue), Alaska, that prompted this collaborative study on the life cycle of a thermokarst lake in the Arctic. Prior to its drainage, the lake expanded from 0.13 ha in 1951 to 0.54 ha in 2021 at lateral rates that ranged from 0.25 to 0.35 m/year. During the drainage event, we estimate that 18,500 m3 of water drained from the lake into Kotzebue Sound, forming a 125-m-long thermo-erosional gully that incised 2 to 14 m in ice-rich permafrost. Between 29 June and 18 August 2022, the drainage gully expanded from 1 m to >10 m wide, mobilizing ~8,500 m3 of material through erosion and thaw. By reconstructing a pre-lake disturbance terrain model, we show that thaw subsidence occurs rapidly (0.78 m/year) upon transition from tundra to lake but that over a seventy-year period it slows to 0.12 m/year. The combination of multiple remote sensing tools and local environmental observations provided a rich data set that allowed us to assess rates of lake expansion relative to rates of sub-lake permafrost thaw subsidence as well as hypothesizing about the potential role of beavers in arctic lake drainage
Restoring habitat for fire-impacted species' across degraded Australian landscapes
In the summer of 2019-2020, southern Australia experienced the largest fires on record, detrimentally impacting the habitat of native species, many of which were already threatened by past and current anthropogenic land use. A large-scale restoration effort to improve degraded species habitat would provide fire-affected species with the chance to recover and persist in burnt and unburnt habitat. To facilitate this, decision-makers require information on priority species needs for restoration intervention, the suite of potential restoration interventions, and the priority locations for applying these interventions. We prioritize actions in areas where restoration would most likely provide cost-effective benefits to priority species (defined by each species proportion of habitat burned, threat status, and vulnerability to fires), by integrating current and future species habitat suitability maps with spatially modelled costs of restoration interventions such as replanting, removing invasive species, and implementing ecologically appropriate fire management. We show that restoring the top similar to 69% (112 million hectares) of the study region (current and future distributions of priority species) accounts for, on average, 95% of current and future habitat for every priority species and costs similar to AUD650 hectare(-1) yr(-1)) annualized over 30 years. This effort would include restoration actions over 6 million hectares of fire-impacted habitat, costing similar to AUD253 million yr(-1) in carbon market revenue if all carbon was remunerated. Our approach highlights the scale, costs, and benefits of targeted restoration activities both inside and outside of the immediate bushfire footprint over vast areas of different land tenures
Evaluation of Mental Health First Aid from the Perspective Of Workplace End UseRs—EMPOWER: protocol of cluster randomised trial phase
Background: Mental Health First Aid (MHFA) is a mental health intervention that teaches people how to identify, understand and help someone who may be experiencing a mental health issue. Reviews of the implementation of MHFA found between 68 and 88% of trained Mental Health First Aiders had used their skills when in contact with someone experiencing mental health difficulties. Reviews evaluating the impact of MHFA suggest positive outcomes. However, to date, there has been no systematic, rigorous evaluation of the impact of MHFA on recipients of the intervention, the organisations providing it and the cost-effectiveness of MHFA overall. This trial will evaluate the effectiveness and cost-effectiveness of MHFA.
Methods: The study is a multi-centred, two-arm clustered randomised controlled trial. Organisations will be randomly allocated to the control or intervention (estimated sample size 800 recipients). The intervention is the standard MHFA intervention provided by Mental Health First Aid England (MHFAE). The control condition will be organisations having a brief consultation from MHFAE on promoting mental health and well-being in the workplace. The primary outcome is health seeking behaviour, measured using the Actual Help Seeking Questionnaire, at 6 months’ follow-up. Data collection will be undertaken at baseline (T0), post-intervention—up to 3 months (T1), at 6 months (T2), 12 months (T3) and 24 months (T4). The primary analysis will be conducted on those participants who receive MHFA, a per protocol analysis.
Discussion: The study is the first to evaluate the effect of MHFA in the workplace on employees with direct and indirect experience of the intervention, when compared with usual practice. Being also the first to assess, systematically, the social impact of MHFA and investigate its cost-effectiveness adds to the originality of the study. The study promises to yield important data, as yet unknown, regarding the effectiveness, cost-effectiveness, implementation issues, and the sustainability of MHFA in the workplace
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