41,589 research outputs found
Promoting Public Health In The Context Of The “Obesity Epidemic”: False Starts And Promising New Directions
In the battle to combat obesity rates in the United States, several misconceptions have dominated policy initiatives. We address those misconceptions, including the notion that restrictive diets lead to long-term weight loss, that stigmatizing obesity is an effective strategy for promoting weight reduction, and that weight and physical health should be considered synonymous with one another. In offering correctives to each of these points, we draw on psychological science to suggest new policies that could be enacted at both the local and national levels. Instead of policies that rely solely on individual willpower, which is susceptible to failure, we recommend those that make use of environmental changes to reduce the amount of willpower necessary to achieve healthy behavior. Ultimately, the most effective policies will promote health rather than any arbitrary level of weight
A review and meta analysis of health state utility values in breast cancer
Background and purpose:
Health-related quality of life is an important issue in the treatment of breast cancer, and health-state utilities are essential for cost-utility analysis. This paper identifies and summarises published utilities for common health-related quality of life outcomes for breast cancer, considers the impact of variation in study designs used, and pools utilities for some breast cancer health states.
Data sources and study selection:
13 databases were searched using key words relating to breast cancer and utility measurement. Articles were included if specified empirical methods for deriving utility values were used and details of the method, including number of respondents, were given. Articles were excluded if values were based on expert opinion or were not unique.
Data extraction and synthesis:
The authors identified 49 articles which met their inclusion criteria, providing 476 unique utilities for breast cancer health states. Where possible, mean utility estimates were pooled using ordinary least squares with utilities clustered within study group and weighted by both number of respondents and inverse of the variance of each utility. Regressions included controls for disease state, utility assessment method and other features of study design.
Results:
Utility values found in the review are summarised for six categories: 1) screening related states, 2) preventative states, 3) adverse events in breast cancer and its treatment, 4) non-specific breast cancer, 5) metastatic breast cancer states and 6) early breast cancer states. Pooled utility values for the latter two categories are estimated, showing base state utility values of between 0.668 and 0.782 for early breast cancer and 0.721 and 0.806 metastatic breast cancer depending upon which model is used. Utilities were found to vary significantly by valuation method, and who conducted the valuation.
Conclusions:
A large number of utility values for breast cancer are available in the literature; the states that these refer to are often complex, making pooling of values problematic
Application of integral operators in the numerical solution of elliptic boundary value problems
Imperial Users onl
Performance of a 28-inch ramjet utilizing gaseous hydrogen at a mach number of 3.6, angles of attack up to 12 deg, and pressure altitudes up to 110,000 feet
Combustion efficiency of gaseous hydrogen fuel for ramjets at very high altitudes and high distortio
The economic approach to resource development in New Zealand
Paper submitted to the Fourth N.Z. Geography Conference, New Zealand Geographical Society (Inc.) Dunedin 1965.The purpose of this paper is to draw attention to the economic aspects of
resource development and to suggest the need for the overall planning of development in New Zealand, and for a more systematic approach to the assessment of individual projects. This will necessitate the use of some of the recently developed techniques of applied economics or operational research.
As a background, it is necessary to draw attention to two significant changes
which have taken place in the economic philosophy of the Western world during the last decade and which will probably influence New Zealand's political
economy during the next. These are the concepts of economic growth and of
indicative planning
Matrix Big Brunch
Following the holographic description of linear dilaton null Cosmologies with
a Big Bang in terms of Matrix String Theory put forward by Craps, Sethi and
Verlinde, we propose an extended background describing a Universe including
both Big Bang and Big Crunch singularities. This belongs to a class of exact
string backgrounds and is perturbative in the string coupling far away from the
singularities, both of which can be resolved using Matrix String Theory. We
provide a simple theory capable of describing the complete evolution of this
closed Universe.Comment: 15 pages, no figures. References adde
Extended Gas in Seyfert Galaxies: Near Infrared Observations of NGC 2110 and Circinus
We present results of near--IR long-slit spectroscopy in the J and K bands of
the Seyfert 2 galaxies NGC 2110 and Circinus, investigating the gaseous
distribution, excitation, reddening and kinematics. In NGC 2110, the emission
line ratio [FeII]/Pa beta increases towards the nucleus (to ~ 7). The nuclear
[Fe II]1.257 (microns) and Pa beta lines are broader (FWHM ~ 500 km/s) than the
H2 (2.121) line (FWHM ~ 300 km/s). Both these results suggest that shocks,
driven by the radio jet, are an important source of excitation of [Fe II]. The
H2 excitation appears to be dominated by X-rays from the nucleus. In Circinus,
both [FeII]/Pa beta and H2/Br gamma decrease from ~ 2 at 4 arcsec from the
nucleus to nuclear values of ~ 0.6 and ~ 1, respectively, suggesting that the
starburst dominates the nuclear excitation, while the AGN dominates the
excitation further out (r > 2 arcsec). For both galaxies, the gaseous
kinematics are consistent with circular rotation in the plane of the disk. Our
rotation curves suggest that the nucleus (identified with the peak of the IR
continuum) is displaced from the kinematic centre of the galaxies. This effect
has been observed previously in NGC 2110 based on the kinematics of optical
emission lines, but the displacement is smaller in the infrared, suggesting the
effect is related to obscuration. The continuum J-K colours of the nuclear
region indicate a red stellar population in NGC 2110 and a reddened young
stellar population in Circinus. Right at the nucleus of both galaxies, the
colours are redder, apparently a result of hot dust emission from the inner
edge of a circumnuclear torus.Comment: 11 pages, 14 figures, accepted for publication in MNRA
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