13 research outputs found

    Study on the synergistic protective effect of Lycium barbarum L. polysaccharides and zinc sulfate on chronic alcoholic liver injury in rats

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    Both Lycium barbarum L. polysaccharides (LBP) and zinc have protective effects on liver injuries. In this paper, LBP and ZnSO4 were combined to study the effects on the prevention of alcoholic liver injury. The rats were divided into six groups, the normal group, alcohol group, zinc sulfate group, LBP group, low‐dose group of ZnSO4, and high‐dose group of ZnSO4 and LBP, used to explore the impact of LBP and ZnSO4 complex on liver lipid metabolism of alcohol, alcohol‐metabolizing enzymes, oxidative damage, and inflammation of the liver. The experimental model was established by gavage treatment, observation, and determination of indexes of rats. The results showed that the combination of LBP and ZnSO4 could significantly decrease the levels of triglyceride (TG), total cholesterol (TC), tumor necrosis factor‐α(TNF‐ɑ), malondialdehyde (MDA), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and the activity of enzyme subtype 2E1 (CYP2E1). It also significantly increased the activities of total superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH‐Px), glutathione peptide (GSH), and alcohol dehydrogenase, effectively improved the liver tissue lesion. What is more, the combination of LBP and ZnSO4 had a synergistic effect on the remission of alcoholic fatty liver, and alleviated chronic alcoholic liver injury by promoting lipid metabolism, inhibiting oxidative stress, controlling inflammatory responses, and regulating the expression and activity of alcohol‐metabolizing enzymes in rats

    Study on the synergistic protective effect of Lycium barbarum

    No full text
    Both Lycium barbarum L. polysaccharides (LBP) and zinc have protective effects on liver injuries. In this paper, LBP and ZnSO4 were combined to study the effects on the prevention of alcoholic liver injury. The rats were divided into six groups, the normal group, alcohol group, zinc sulfate group, LBP group, low‐dose group of ZnSO4, and high‐dose group of ZnSO4 and LBP, used to explore the impact of LBP and ZnSO4 complex on liver lipid metabolism of alcohol, alcohol‐metabolizing enzymes, oxidative damage, and inflammation of the liver. The experimental model was established by gavage treatment, observation, and determination of indexes of rats. The results showed that the combination of LBP and ZnSO4 could significantly decrease the levels of triglyceride (TG), total cholesterol (TC), tumor necrosis factor‐α(TNF‐ɑ), malondialdehyde (MDA), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and the activity of enzyme subtype 2E1 (CYP2E1). It also significantly increased the activities of total superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH‐Px), glutathione peptide (GSH), and alcohol dehydrogenase, effectively improved the liver tissue lesion. What is more, the combination of LBP and ZnSO4 had a synergistic effect on the remission of alcoholic fatty liver, and alleviated chronic alcoholic liver injury by promoting lipid metabolism, inhibiting oxidative stress, controlling inflammatory responses, and regulating the expression and activity of alcohol‐metabolizing enzymes in rats

    Piezoelectric and ferroelectric properties of Na0.5Bi4.5Ti4O15–BaTiO3 composite ceramics with Mg doping

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    As one of the representatives of lead-free NBT ceramics, Na0.5Bi4.5Ti4O15 has still attracted much attention due to its excellent dielectric properties and has become the focus of research. However, its piezoelectric properties are far from satisfactory. In order to improve the piezoelectric properties of Na0.5Bi4.5Ti4O15, Na0.5Bi4.5Ti4−xMgxOy–BaTiO3 (NBTM–BT) composite ceramics were synthesized by a conventional mixed oxide route and sintered at 1040∘C through two-step method. We optimized the electrical properties of NBTM–BT by changing the stoichiometric ratio of Mg content and studied its microscopic mechanism. The piezoelectric coefficient (d33) is stable at about 20 pC/N. Moreover, the maximum remanent polarization (2Pr) of the ceramic is 3.08ÎŒC/cm2 with the coercive field of 18.01kV/cm. The dielectric constant and dielectric loss for Na0.5Bi4.5Ti3.96Mg0.04–BT composite ceramic were found to be 486 and 0.17 at 10kHz, respectively. The characteristic peaks of BT and Na0.5Bi4.5Ti4O15 can be observed clearly from the X-ray diffraction analysis. SEM analysis showed that all samples were well crystallized. Consequently, the piezoelectric and ferroelectric properties of Na0.5Bi4.5Ti4O15–BT composite ceramic will be enhanced much by Mg doping, which means it has a wider range of applications in electronic devices such as piezoelectric devices

    High Efficiency and Color Rendering Quantum Dots White Light Emitting Diodes Optimized by Luminescent Microspheres Incorporating

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    In this research, we have developed an approach by incorporating quantum dots (QDs) with red emission into mesoporous silica microspheres through a non-chemical process and obtained luminescent microspheres (LMS). Owing to the lattice structure of LMS, QDs were effectively protected from intrinsic aggregation in matrix and surface deterioration by encapsulant, oxygen and moisture. The LMS composite has therefore maintained large extent luminescent properties of QDs, espe-cially for the high quantum efficiency. Moreover, the fabricated white light emitting diode (WLED) utilizing LMS and YAG:Ce yellow phosphor has demonstrated excellent light performance with color coordinates around (x = 0.33, y = 0.33), correlated color temperature between 5100 and 5500 K and color rendering index of Ra = 90, R9 = 95. The luminous efficiency of the WLED has reached up to a new record of 142.5 lm/W at 20 mA. LMS provide a promising way to practically apply QDs in lightings and displays with high efficiency as well as high stability

    Manipulation of Surface Plasmon Resonance in Sub-Stoichiometry Molybdenum Oxide Nanodots through Charge Carrier Control Technique

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    Semiconductor nanocrystals are intriguing because they show surface plasmon absorption features like noble metallic nanoparticles. In contrast with metal, manipulation of their unique plasmonic resonance could be easily realized by the free-carrier concentration. Here, it is demonstrated that MoO<sub>3–<i>x</i></sub> nanodots can exhibit striking surface plasmon resonance located at near-infrared region under treatment of two different reducing agents. Furthermore, the tunable resonance mode has been achieved through appropriate redox processes. Refractive index sensing has been demonstrated by monitoring the plasmonic peak. The improved sensing application is ascribed to the enhanced electric field in the plasmonic nanocrystals. These new insights into MoO<sub>3–<i>x</i></sub> nanodots pave a way to develop novel plasmonic applications such as photothermal therapy, light harvesting, and sensing
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