Flavor changing neutrino interactions and CP violation in neutrino oscillations

We investigate the interference effects of non-standard neutrino-matter interactions (NSNI) with the mass-induced neutrino oscillations. The NSNI is composed of flavor-changing neutrino interactions (FCNI) and flavor-diagonal neutrino interactions (FDNI). Both of the interactions are introduced in the \nu_\mu -\nu_\tau sector and the \nu_e -\nu_\mu sector in order to study their effects in \nu_\mu\to\nu_\tau and \nu_\mu\to\nu_e oscillations, respectively. The FCNI effect proves to possibly dominate the CP violating effect and significantly survive as a fake CP violating effct in the neutrino energy region where the pure CP violating effect, ordinary matter effect and FDNI effect fall, for example, above 4 GeV at the baseline of L=730 km in the \nu_\mu\to\nu_\tau oscillation for the maximum parameter values of FCNI and FDNI allowed by the atmospheric neutrino oscillation data. The FCNI and FDNI effects on CP violation in the $\nu_\mu\to\nu_e$ oscillation are negligibly small due to the stringent constraints on FCNI from the bounds on lepton flavor violating processes and on FDNI from the limits on lepton universality violation.Comment: 18 pages in LaTeX2e, 12 ps figures. The discussion of detectability of the CP violation is delete

Reorganization of functional brain network architecture in chronic osteoarthritis pain

Osteoarthritis (OA) manifests with chronic pain, motor impairment, and proprioceptive changes. However, the role of the brain in the disease is largely unknown. Here, we studied brain networks using the mathematical properties of graphs in a large sample of knee and hip OA (KOA, n = 91; HOA, n = 23) patients. We used a robust validation strategy by subdividing the KOA data into discovery and testing groups and tested the generalizability of our findings in HOA. Despite brain global topological properties being conserved in OA, we show there is a network wide pattern of reorganization that can be captured at the subject-level by a single measure, the hub disruption index. We localized reorganization patterns and uncovered a shift in the hierarchy of network hubs in OA: primary sensory and motor regions and parahippocampal gyrus behave as hubs and insular cortex loses its central placement. At an intermediate level of network structure, frontoparietal and cingulo-opercular modules showed preferential reorganization. We examined the association between network properties and clinical correlates: global disruption indices and isolated degree properties did not reflect clinical parameters; however, by modeling whole brain nodal degree properties, we identified a distributed set of regions that reliably predicted pain intensity in KOA and generalized to hip OA. Together, our findings reveal that while conserving global topological properties, brain network architecture reorganizes in OA, at both global and local scale. Network connectivity related to OA pain intensity is dissociated from the major hub disruptions, challenging the extent of dependence of OA pain on nociceptive signaling.CCDRN, Grant/Award Number: Norte‐08‐5369‐FSE‐000026; Unilabs Boavista and the Grünenthal Young Pain Researcher 2017 Grant; Luso‐American Development Foundation R&D@PhD Scholarship Grant; OARSI Collaborative Scholarship 201

Electric Dipole Moments of Neutron and Electron in Two-Higgs-Doublet Model with Maximal CPCP violation

We study the electric dipole moments(EDM) of the neutron and the electron in the two-Higgs-doublet model, in the case that $CP$ symmetry is violated maximally in the neutral Higgs sector. We take account of the Weinberg's operator O_{3g}=GG\t G as well as the operator $O_{qg}=\bar q\sigma\tilde Gq$ for the neutron, and the Barr-Zee diagrams for the electron. It is found that the predicted neutron EDM could be considerably reduced by the destructive contribution of the two Higgs scalars to get the lower value than the experimental bound. As to the electron EDM, the predicted value is smaller in one order than the experimental one.Comment: 15pages, UWThPh-1994-48, AUE-08-94, US-94-06. The post-script files of figures will be sent by request by electric mai