If Statues Could Speak

You don\u27t sit down and just start chiseling on a piece of stone to produce a statue- it\u27s not that easy. A rough sketch, miniature model and then a full-sized model of clay are done first. With this in mind, the next time you pass a statue, look at it, think about it, speak to it. Maybe it will speak back

The Iowa Homemaker vol.32, no.3

Introducing Dr. Helen LeBaron, Jean McGhie, page 7 Make Every Penny Count, Joyce Roos, page 8 Best Years of Your Life, Salli Hearst, page 9 Spare Time Pay Offs, Dorothy Owen, page 10 New Additions – Added Pleasure, Dorothy Will, page 14 If Statues Could Speak, Marilyn Wachtel, page 15 Happy Living Through Cooperative Living, Mary Grout and Elinor Holmberg, page 16 What’s New, Evelynn Toulouse and Dorothy Will, page 18 Clip and Save Your Fall Quarter Calendar, page 24 Here’s An Idea, page 26 Tradition Dictates, Ruth Anderson, page 28 Trends, Joanne Ryals, page 3

Global Retinoblastoma Presentation and Analysis by National Income Level.

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4%) were female. Most patients (n = 3685 [84.7%]) were from low- and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 [62.8%]), followed by strabismus (n = 429 [10.2%]) and proptosis (n = 309 [7.4%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 [95% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 [95% CI, 4.30-7.68]). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs

If Statues Could Speak

You don't sit down and just start chiseling on a piece of stone to produce a statue- it's not that easy. A rough sketch, miniature model and then a full-sized model of clay are done first. With this in mind, the next time you pass a statue, look at it, think about it, speak to it. Maybe it will speak back!</p

The Iowa Homemaker vol.32, no.3

Introducing Dr. Helen LeBaron, Jean McGhie, page 7 Make Every Penny Count, Joyce Roos, page 8 Best Years of Your Life, Salli Hearst, page 9 Spare Time Pay Offs, Dorothy Owen, page 10 New Additions – Added Pleasure, Dorothy Will, page 14 If Statues Could Speak, Marilyn Wachtel, page 15 Happy Living Through Cooperative Living, Mary Grout and Elinor Holmberg, page 16 What’s New, Evelynn Toulouse and Dorothy Will, page 18 Clip and Save Your Fall Quarter Calendar, page 24 Here’s An Idea, page 26 Tradition Dictates, Ruth Anderson, page 28 Trends, Joanne Ryals, page 30</p

Quality of life in long-term survivors after liver transplantation: impact of recurrent viral hepatitis C virus hepatitis

Post liver transplant recurrence of infection with hepatitis C virus (HCV) occurs in approximately 50 of patients transplanted because of HCV-related liver disease. The aim of this study was to assess long-term quality of life, psychologic distress, and coping in patients with recurrent HCV after liver transplantation in comparison to patients transplanted for other etiologies of underlying liver disease. All liver transplant recipients transplanted at a University affiliated Veterans Affairs Medical Center who had greater than 6 months follow-up were sent a questionnaire investigating quality of life (assessed by Medical Outcomes study health survey SF-36), depression (assessed by Beck Depression Inventory), total mood disturbance (assessed by Profile of Mood States scale), coping (assessed by Billing and Moos Inventory of coping with illnesses), and employment status. Lower Beck Depression Inventory score (p = 0.001), lower mood disturbance score (p = 0.0001), overall satisfaction with present work (p = 0.0001), and lesser use of avoidant coping (p = 0.06) were predictors of better quality of life in long-term survivors of liver transplantation. At a mean follow-up of 4 yr after liver transplantation, patients with histopathologically diagnosed recurrent viral HCV hepatitis had significantly lower global quality of life score (mean score of 76.4 versus 86.2, p = 0.011) and physical functioning score (mean score 20 versus 25, p = 0.015), as compared to all other patients. In summary, quality of life and physical functioning were significantly impaired in liver transplant recipients with histopathologically diagnosed recurrent HCV hepatitis, as compared to those whose HCV hepatitis had not recurred or those transplanted for other reasons