5,592 research outputs found
Graphite/Larc-160 technology demonstration segment test results
A structural test program was conducted on a Celion/LARC-160 graphite/polyimide technology demonstration segment (TDS) to verify the technology. The 137 x 152 cm (54 x 60 in.) TDS simulates a full-scale section of the orbiter composite body flap design incorporating three ribs and extending from the forward cove back to the rear spar. The TDS was successfully subjected to mechanical loads and thermal environments (-170 to 316 C) simulating 100 shuttle orbiter missions. Successful completion of the test program verified the design, analysis, and fabrication methodology for bonded Gr/PI honeycomb sandwich structure and demonstration that Gr/PI composite technology readiness is established
Sub-picosecond compression by velocity bunching in a photo-injector
We present an experimental evidence of a bunch compression scheme that uses a
traveling wave accelerating structure as a compressor. The bunch length issued
from a laser-driven radio-frequency electron source was compressed by a factor
>3 using an S-band traveling wave structure located immediately downstream from
the electron source. Experimental data are found to be in good agreement with
particle tracking simulations.Comment: 19 pages, 9 figures, submitted to Phys. Rev. Spec. Topics A&
Millisecond accuracy video display using OpenGL under Linux
To measure people’s reaction times to the nearest millisecond, it is necessary to know exactly when
a stimulus is displayed. This article describes how to display stimuli with millisecond accuracy on a
normal CRT monitor, using a PC running Linux. A simple C program is presented to illustrate how this
may be done within X Windows using the OpenGL rendering system. A test of this system is reported
that demonstrates that stimuli may be consistently displayed with millisecond accuracy. An algorithm
is presented that allows the exact time of stimulus presentation to be deduced, even if there are relatively
large errors in measuring the display time
Pursuit of purity: Measurement of chelation binding affinities for NOTA, DOTA, and desferal with applications to effective specific activity
Introduction
The effective specific activity of a radioisotope is an indirect and highly useful way to describe a radioactive sample’s purity. A high effective specific activity combines the concept of an isotopically pure product with suitability via selectivity of a particular chelating body. The primary goals of this work are twofold: 1) To determine which metallic impurities have the largest impact on the effective specific activity for a given chelator, and 2) to form a model based on the binding affinities of each metal for to calculate a ‘theoretical effective specific activ-ity’ from broad band trace metal analysis. If successful, this information can be used to guide the production of high specific activity products through the systematic elimination of high-impact metallic impurities.
Material and Methods
Phosphor plate thin layer chromatography (TLC) was used to measure the effective specific activ-ity of 64Cu by NOTA and DOTA, and 89Zr by des-feral (DF). Typical measured effective specific activities are 2–5 Ci/μmol for 64Cu and 1–2 Ci/μmol for 89Zr.
Samples were created containing increasing cod competitive burdens (X) of CuCl2, ZnCl2, FeCl2, NiCl2, CrCl3, CoCl2, MnCl2, and YCl3. Standard concentrations were measured by microwave plasma atomic emission spectrometry. 50 pmol of NOTA, DOTA, or DF were added following the activity aliquots of 64Cu or 89Zr. Labeling efficien-cies (64Cu-NOTA, 64Cu-DOTA, 89Zr-DF) were measured using TLC’s, and were fit by linear regression to the form f(X) = b/(1 − AX), where A is the chelation affinity (inverse of dissociation constant) and X is the molar ratio of the metallic impurity to the amount of chelator.
Results and Conclusion
Affinity of Zr for DF was assumed to be unity, while the affinities of Cu for NOTA and DOTA were explicitly measured and were found to be 0.93 ± 0.13 and 5.2 ± 3.2 respectively.
It was found that Cu had the highest affinity for NOTA by a factor of 266, and that Zr had the highest affinity for DF by a factor of 40.
• In order of decreasing affinity to NOTA: Cu, Zn, Fe, Co, Cr, Y, and Ni
• In order of decreasing affinity to DOTA: Cu, Y, Zn, Co, Ni, Cr, and Fe
• In order of decreasing affinity to DF: Zr, Y, Cu, Zn, Ni, Fe, Co, Cr
These results suggest that aside from the carrier element it is most important to remove zinc from 64Cu products prior to chelation with NOTA and yttrium from 64Cu and 89Zr products prior to chelation with DOTA and DF, respectively. Therefore, it is logical to believe that 89Zr effective specific activities could be greatly improved by secondary separations with the goal of re-moving additional yttrium target material.
Chelation affinities of NOTA, DOTA, and DF for several common metals have successfully been investigated. These values will guide our future attempts to provide high effective specific activity 64¬Cu and 89Zr. Furthermore, a preliminary model has been formed to calculate effective specific activity from the quantitative broad band analysis of trace metals. Future work will include chelator affinity measurements for other likely contaminants, such as scandium, titanium, zirconium, molybdenum, niobium, gold, gallium, and germanium. Details will be presented
Excitation functions for (p,x) reactions of niobium in the energy range of E = 40-90 MeV
A stack of thin Nb foils was irradiated with the 100 MeV proton beam at Los
Alamos National Laboratory's Isotope Production Facility, to investigate the
Nb(p,4n)Mo nuclear reaction as a monitor for intermediate energy
proton experiments and to benchmark state-of-the-art reaction model codes. A
set of 38 measured cross sections for Nb(p,x) and
Cu(p,x) reactions between 40-90 MeV, as well as 5 independent
measurements of isomer branching ratios, are reported. These are useful in
medical and basic science radionuclide productions at intermediate energies.
The Cu(p,x)Co, Cu(p,x)Zn, and
Cu(p,x)Zn reactions were used to determine proton
fluence, and all activities were quantified using HPGe spectrometry. Variance
minimization techniques were employed to reduce systematic uncertainties in
proton energy and fluence, improving the reliability of these measurements. The
measured cross sections are shown to be in excellent agreement with literature
values, and have been measured with improved precision compared with previous
measurements. This work also reports the first measurement of the
Nb(p,x)Rb reaction, and of the independent cross
sections for Cu(p,x)Mn and
Nb(p,x)Y in the 40-90 MeV region. The effects of
Si(p,x)Na contamination, arising from silicone
adhesive in the Kapton tape used to encapsulate the aluminum monitor foils, is
also discussed as a cautionary note to future stacked-target cross section
measurements. \emph{A priori} predictions of the reaction modeling codes CoH,
EMPIRE, and TALYS are compared with experimentally measured values and used to
explore the differences between codes for the Nb(p,x) and
Cu(p,x) reactions.Comment: 34 pages, submitted to NIM-
The Peak Brightness and Spatial Distribution of AGB Stars Near the Nucleus of M32
The bright stellar content near the center of the Local Group elliptical
galaxy M32 is investigated with 0.12 arcsec FWHM H and K images obtained with
the Gemini Mauna Kea telescope. Stars with K = 15.5, which are likely evolving
near the tip of the asymptotic giant branch (AGB), are resolved to within 2
arcsec of the nucleus, and it is concluded that the peak stellar brightness
near the center of M32 is similar to that in the outer regions of the galaxy.
Moreover, the projected density of bright AGB stars follows the visible light
profile to within 2 arcsec of the nucleus, indicating that the brightest stars
are well mixed throughout the galaxy. Thus, there is no evidence for an age
gradient, and the radial variations in spectroscopic indices and ultraviolet
colors that have been detected previously must be due to metallicity and/or
some other parameter. We suggest that either the bright AGB stars formed as
part of a highly uniform and coherent galaxy-wide episode of star formation, or
they originated in a separate system that merged with M32.Comment: 9 pages of text, 3 figures. ApJ (Letters) in pres
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