25,030 research outputs found
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Provision of secondary frequency regulation by coordinated dispatch of industrial loads and thermal power plants
Demand responsive industrial loads with high thermal inertia have potential to provide ancillary service for frequency regulation in the power market. To capture the benefit, this study proposes a new hierarchical framework to coordinate the demand responsive industrial loads with thermal power plants in an industrial park for secondary frequency control. In the proposed framework, demand responsive loads and generating resources are coordinated for optimal dispatch in two-time scales: (1) the regulation reserve of the industrial park is optimally scheduled in a day-ahead manner. The stochastic regulation signal is replaced by the specific extremely trajectories. Furthermore, the extremely trajectories are achieved by the day-ahead predicted regulation mileage. The resulting benefit is to transform the stochastic reserve scheduling problem into a deterministic optimization; (2) a model predictive control strategy is proposed to dispatch the industry park in real time with an objective to maximize the revenue. The proposed technology is tested using a real-world industrial electrolysis power system based upon Pennsylvania, Jersey, and Maryland (PJM) power market. Various scenarios are simulated to study the performance of the proposed approach to enable industry parks to provide ancillary service into the power market. The simulation results indicate that an industrial park with a capacity of 500 MW can provide up to 40 MW ancillary service for participation in the secondary frequency regulation. The proposed strategy is demonstrated to be capable of maintaining the economic and secure operation of the industrial park while satisfying performance requirements from the real world regulation market
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The cumulative effects of known susceptibility variants to predict primary biliary cirrhosis risk.
Multiple genetic variants influence the risk for development of primary biliary cirrhosis (PBC). To explore the cumulative effects of known susceptibility loci on risk, we utilized a weighted genetic risk score (wGRS) to evaluate whether genetic information can predict susceptibility. The wGRS was created using 26 known susceptibility loci and investigated in 1840 UK PBC and 5164 controls. Our data indicate that the wGRS was significantly different between PBC and controls (P=1.61E-142). Moreover, we assessed predictive performance of wGRS on disease status by calculating the area under the receiver operator characteristic curve. The area under curve for the purely genetic model was 0.72 and for gender plus genetic model was 0.82, with confidence limits substantially above random predictions. The risk of PBC using logistic regression was estimated after dividing individuals into quartiles. Individuals in the highest disclosed risk group demonstrated a substantially increased risk for PBC compared with the lowest risk group (odds ratio: 9.3, P=1.91E-084). Finally, we validated our findings in an analysis of an Italian PBC cohort. Our data suggested that the wGRS, utilizing genetic variants, was significantly associated with increased risk for PBC with consistent discriminant ability. Our study is a first step toward risk prediction for PBC
A (p,q) Deformation of the Universal Enveloping Superalgebra U(osp(2/2))
We investigate a two parameter quantum deformation of the universal
enveloping orthosymplectic superalgebra U(osp(2/2)) by extending the
Faddeev-Reshetikhin-Takhtajan formalism to the supersymetric case. It is shown
that possesses a non-commutative, non-cocommutative Hopf
algebra structure. All the results are expressed in the standard form using
quantum Chevalley basis.Comment: 8 pages; IC/93/41
Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data
Next-generation sequencing (NGS) technologies have matured considerably since their introduction and a focus has been placed on developing sophisticated analytical tools to deal with the amassing volumes of data. Chromatin immunoprecipitation sequencing (ChIP-seq), a major application of NGS, is a widely adopted technique for examining protein-DNA interactions and is commonly used to investigate epigenetic signatures of diffuse histone marks. These datasets have notoriously high variance and subtle levels of enrichment across large expanses, making them exceedingly difficult to define. Windows-based, heuristic models and finite-state hidden Markov models (HMMs) have been used with some success in analyzing ChIP-seq data but with lingering limitations. To improve the ability to detect broad regions of enrichment, we developed a stochastic Bayesian Change-Point (BCP) method, which addresses some of these unresolved issues. BCP makes use of recent advances in infinite-state HMMs by obtaining explicit formulas for posterior means of read densities. These posterior means can be used to categorize the genome into enriched and unenriched segments, as is customarily done, or examined for more detailed relationships since the underlying subpeaks are preserved rather than simplified into a binary classification. BCP performs a near exhaustive search of all possible change points between different posterior means at high-resolution to minimize the subjectivity of window sizes and is computationally efficient, due to a speed-up algorithm and the explicit formulas it employs. In the absence of a well-established "gold standard" for diffuse histone mark enrichment, we corroborated BCP's island detection accuracy and reproducibility using various forms of empirical evidence. We show that BCP is especially suited for analysis of diffuse histone ChIP-seq data but also effective in analyzing punctate transcription factor ChIP datasets, making it widely applicable for numerous experiment types
Quenching and Tomography from RHIC to LHC
We compare fully perturbative and fully nonperturbative pictures of high-pT
energy loss calculations to the first results from LHC. While over-suppressed
compared to published ALICE data, parameter-free pQCD predictions based on the
WHDG energy loss model constrained to RHIC data simultaneously describe well
the preliminary CMS hadron suppression, ATLAS charged hadron v2, and ALICE D
meson suppression; we also provide for future reference WHDG predictions for B
meson RAA. However, energy loss calculations based on AdS/CFT also
qualitatively describe well the RHIC pion and non-photonic electron suppression
and LHC charged hadron suppression. We propose the double ratio of charm to
bottom quark RAA will qualitatively distinguish between these two energy loss
pictures.Comment: 4 pages, 3 figures. Proceedings for Quark Matter 201
ASTROD, ASTROD I and their gravitational-wave sensitivities
ASTROD (Astrodynamical Space Test of Relativity using Optical Devices) is a
mission concept with three spacecraft -- one near L1/L2 point, one with an
inner solar orbit and one with an outer solar orbit, ranging coherently with
one another using lasers to test relativistic gravity, to measure the solar
system and to detect gravitational waves. ASTROD I with one spacecraft ranging
optically with ground stations is the first step toward the ASTROD mission. In
this paper, we present the ASTROD I payload and accelerometer requirements,
discuss the gravitational-wave sensitivities for ASTROD and ASTROD I, and
compare them with LISA and radio-wave PDoppler-tracking of spacecraft.Comment: presented to the 5th Edoardo Amaldi Conference (July 6-11, 2003) and
submitted to Classical and Quantum Gravit
Spin relaxation in a GaAs quantum dot embedded inside a suspended phonon cavity
The phonon-induced spin relaxation in a two-dimensional quantum dot embedded
inside a semiconductor slab is investigated theoretically. An enhanced
relaxation rate is found due to the phonon van Hove singularities. Oppositely,
a vanishing deformation potential may also result in a suppression of the spin
relaxation rate. For larger quantum dots, the interplay between the spin orbit
interaction and Zeeman levels causes the suppression of the relaxation at
several points. Furthermore, a crossover from confined to bulk-like systems is
obtained by varying the width of the slab.Comment: 5 pages, 4 figures, to apper in Phys. Rev. B (2006
Grouping time series by pairwise measures of redundancy
A novel approach is proposed to group redundant time series in the frame of
causality. It assumes that (i) the dynamics of the system can be described
using just a small number of characteristic modes, and that (ii) a pairwise
measure of redundancy is sufficient to elicit the presence of correlated
degrees of freedom. We show the application of the proposed approach on fMRI
data from a resting human brain and gene expression profiles from HeLa cell
culture.Comment: 4 pages, 8 figure
Sub and Super-Luminal Propagation of Intense Pulses in Media with Saturated and Reverse Absorption
We develop models for the propagation of intense pulses in solid state media
which can have either saturated absorption or exhibit reverse absorption . We
show that the experiments of Bigelow {\it et al.}[Phys. Rev. Lett. {\bf 90},
113903 (2003); Science {\bf 301}, 200 (2003).] on subluminal propagation in
Ruby and superluminal propagation in Alexandrite are well explained by
modelling them as three level and four level systems coupled to Maxwell
equations. We present results well beyond the traditional pump-probe approach.Comment: 4 pages, 6 figure
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