2,675 research outputs found
CASPR: Judiciously Using the Cloud for Wide-Area Packet Recovery
We revisit a classic networking problem -- how to recover from lost packets
in the best-effort Internet. We propose CASPR, a system that judiciously
leverages the cloud to recover from lost or delayed packets. CASPR supplements
and protects best-effort connections by sending a small number of coded packets
along the highly reliable but expensive cloud paths. When receivers detect
packet loss, they recover packets with the help of the nearby data center, not
the sender, thus providing quick and reliable packet recovery for
latency-sensitive applications. Using a prototype implementation and its
deployment on the public cloud and the PlanetLab testbed, we quantify the
benefits of CASPR in providing fast, cost effective packet recovery. Using
controlled experiments, we also explore how these benefits translate into
improvements up and down the network stack
Bulk scalar field in DGP braneworld cosmology
We investigated the effects of bulk scalar field in the braneworld
cosmological scenario. The Friedmann equations and acceleration condition in
presence of the bulk scalar field for a zero tension brane and cosmological
constant are studied. In DGP model the effective Einstein equation on the brane
is obtained with bulk scalar field. The rescaled bulk scalar field on the brane
in the DGP model behaves as an effective four dimensional field, thus standard
type cosmology is recovered. In present study of the DGP model, the late-time
accelerating phase of the universe can be explained .Comment: 10 pages, to appear in JCA
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Creating a center for global health at the University of Wisconsin-Madison.
Globalization, migration, and widespread health disparities call for interdisciplinary approaches to improve health care at home and abroad. Health professions students are pursuing study abroad in increasing numbers, and universities are responding with programs to address these needs. The University of Wisconsin (UW)-Madison schools of medicine and public health, nursing, pharmacy, veterinary medicine, and the division of international studies have created an interdisciplinary center for global health (CGH). The CGH provides health professions and graduate students with courses, field experiences, and a new Certificate in Global Health. Educational programs have catalyzed a network of enthusiastic UW global health scholars. Partnerships with colleagues in less economically developed countries provide the foundation for education, research, and service programs. Participants have collaborated to improve the education of health professionals and nutrition in Uganda; explore the interplay between culture, community development, and health in Ecuador; improve animal health and address domestic violence in Mexico; and examine successful public health efforts in Thailand. These programs supply students with opportunities to understand the complex determinants of health and structure of health systems, develop adaptability and cross-cultural communication skills, experience learning and working in interdisciplinary teams, and promote equity and reduce health disparities at home and abroad. Based on the principles of equity, sustainability, and reciprocity, the CGH provides a strong foundation to address global health challenges through networking and collaboration among students, staff, and faculty within the UW and beyond
Perbedaan Hasil Belajar Matematika Siswa antara yang Mendapatkan Model Pembelajaran Brain Based Learning dengan Numbered Head Together
The research was conducted to distinguish the two models , this is Brain Based Learning ( BBL ) with the Numbered Head Together ( NHT ) to see the extent to which the two models are instrumental in improving the learning outcomes of students learning mathematics . Authors wanted to see if there are differences in mathematics achievement between students who received Brain Based Learning ( BBL ) with Numbered Head Together ( NHT ) ? . The method that I use in this study is experimental research that is giving treatment to two different classes . The population in this study were all students class VII of SMP Negeri 1 Cikajang with a randomly selected sample of the class VII- C and class VII - D . The instrument used to measure student learning outcomes in the form mathematics objective tests , administered before and after the treatment the author gives a treat . From the analysis of the Mann Whitney test , to test initial value Zhitung = 1.72 and Ztabel = 2.24 with a significance level of 5 % ( α = 0.05 ) zhitung which is located in the reception area Ho , Ho is accepted then it means there is no difference initial ability between experimental classes experiment I and experiment II . While the results of Mann Whitney test to post test at significance level of 5 % ( α = 0.05 ) , zhitung = 3.18 using the two test sides of Zhitung value = 3.18 > Ztabel = 2.24 , in other words zhitung rejection of Ho is in the region , in other words Ha accepted . It means that there are differences in mathematics outcomes between students who received learning model with Brain Based Learning (BBL) with Numbered Head Together (NHT)
Perbandingan Metode Steam Distillation Dan Steam-Hydro Distillation Dengan Microwave Terhadap Jumlah Rendemen Serta Mutu Minyak Daun Cengkeh (Syzygium Aromaticum)
Penelitian ini bertujuan mempelajari dan membandingkan proses pengambilan minyak dari daun cengkeh kering dengan menggunakan metode steam distillation dan steam-hydro distillation dengan pemanfaatan gelombang mikro (microwave). Beberapa faktor seperti pengaruh waktu operasi, perlakuan bahan (dicacah ±0.5–1 cm dan utuh), dan massa bahan juda dipelajari untuk mendapatkan rendemen dan mutu minyak cengkeh yang sesuai standar SNI. Metode yang digunakan adalah steam distillation dan steam-hydro distillation dengan microwave. Pada metode steam-hydro distillation dengan microwave ditambahkan solvent berupa air pada daun cengkeh untuk melarutkan minyak yang ada di dalamnya. Kondisi operasi untuk kedua metode ini adalah tekanan atmosferik (1 atm) dan suhu steam 108oC. Variabel massa yang digunakan adalah pada massa 50, 75, 100, dan 125 gram. Secara prinsip, steam yang dihasilkan mengangkat minyak dalam destiler kemudian steam dan uap minyak dikondensasi. Distilat yang berupa campuran minyak dipisahkan dari air sehingga didapatkan minyak cengkeh murni. Dari pernelitian yang dilakukan, pengambilan minyak cengkeh menggunakan metode steam-hydro distillation dengan microwave menghasilkan rendemen lebih banyak 0.07% sampai 1.77% untuk daun utuh dan untuk 0.03% sampai 1.96% daun cacah jika dibandingkan dengan metode steam distillation. Waktu optimum untuk metode steam distillation adalah 6 jam sedangkan untuk steam-hydro distillation dengan microwave adalah 2.5 jam. Setelah waktu optimum, rendemen minyak cengkeh yang dihasilkan cenderung konstan. Pencacahan bahan meningkatkan jumlah rendemen minyak cengkeh yang dihasilkan sebesar 0.05% sampai 0.36% untuk metode steam distillation dan 0.19% sampai 0.6%. untuk metode steam-hydro distillation dengan microwave. Rendemen minyak optimum untuk metode steam distillation pada 75 gram sedangkan untuk steam-hydro distillation dengan microwave pada 125 gram
An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behavior
Serpins are important regulators of proteolytic pathways with an antiprotease activity that involves a conformational transition from a metastable to a hyperstable state. Certain mutations permit the transition to occur in the absence of a protease; when associated with an intermolecular interaction, this yields linear polymers of hyperstable serpin molecules, which accumulate at the site of synthesis. This is the basis of many pathologies termed the serpinopathies. We have previously identified a monoclonal antibody (mAb4B12) that, in single-chain form, blocks α1-Antitrypsin (α1-AT) polymerisation in cells. Here, we describe the structural basis for this activity. The mAb4B12 epitope was found to encompass residues Glu32, Glu39 and His43 on helix A and Leu306 on helix I. This is not a region typically associated with the serpin mechanism of conformational change, and correspondingly the epitope was present in all tested structural forms of the protein. Antibody binding rendered β-sheet A - on the opposite face of the molecule - more liable to adopt an 'open' state, mediated by changes distal to the breach region and proximal to helix F. The allosteric propagation of induced changes through the molecule was evidenced by an increased rate of peptide incorporation and destabilisation of a preformed serpin-enzyme complex following mAb4B12 binding. These data suggest that prematurely shifting the β-sheet A equilibrium towards the 'open' state out of sequence with other changes suppresses polymer formation. This work identifies a region potentially exploitable for a rational design of ligands that is able to dynamically influence α1-AT polymerisation
Canonical form of Hamiltonian matrices
On the basis of shell model simulations, it is conjectured that the Lanczos
construction at fixed quantum numbers defines---within fluctuations and
behaviour very near the origin---smooth canonical matrices whose forms depend
on the rank of the Hamiltonian, dimensionality of the vector space, and second
and third moments. A framework emerges that amounts to a general Anderson model
capable of dealing with ground state properties and strength functions. The
smooth forms imply binomial level densities. A simplified approach to canonical
thermodynamics is proposed.Comment: 4 pages 6 figure
Cenozoic paleoceanography 1986: An introduction
New developments in Cenozoic paleoceanography include the application of climate models and atmospheric general circulation models to questions of climate reconstruction, the refinement of conceptual models for interpretation of the carbon isotope record in terms of carbon mass balance, paleocirculation, paleoproductivity, and the regional mapping of paleoceanographic events by acoustic stratigraphy. Sea level change emerges as a master variable to which changes in the ocean environment must be traced in many cases, and tests of the onlap-offlap paradigm therefore are of crucial importance
Additional experimental evidence for a solar influence on nuclear decay rates
Additional experimental evidence is presented in support of the recent
hypothesis that a possible solar influence could explain fluctuations observed
in the measured decay rates of some isotopes. These data were obtained during
routine weekly calibrations of an instrument used for radiological safety at
The Ohio State University Research Reactor using Cl-36. The detector system
used was based on a Geiger-Mueller gas detector, which is a robust detector
system with very low susceptibility to environmental changes. A clear annual
variation is evident in the data, with a maximum relative count rate observed
in January/February, and a minimum relative count rate observed in July/August,
for seven successive years from July 2005 to June 2011. This annual variation
is not likely to have arisen from changes in the detector surroundings, as we
show here.Comment: 8 pages, 6 figure
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