Evaluating Mesolithic settlement patterns in mountain environments (Dolomites, Eastern Italian Alps): the role of research biases and locational strategies

The wealth of Mesolithic evidence in the Alpine environments makes it possible to attempt a reconstruction of highland settlement patterns based on the distribution of known sites. However, just how representative this site distribution is has not yet been fully tested and the impact of research biases on the spatial organisation of Mesolithic findspots is not clear. In order to tackle these issues the locational pattern of Mesolithic sites recorded in an upland area of the Venetian Dolomites (North-Eastern Italy) was analysed. Point pattern analysis was used to correlate site distribution with two sets of covariates mirroring research biases and prehistoric settlement preferences. Point-process models were created and compared using both standard Akaike and Bayesian Information Criteria. Results indicate that both factors equally influence the current site distribution. The low number of statistically significant variables - slope and land-use - suggests the existence of additional variables that were not considered. An additional model helped us explore the importance of alternative variables and provided new perspectives for future investigation of high-altitude Mesolithic landscapes, with particular attention to highland mobility

Can medical products be developed on a non-profit basis? Exploring product development partnerships for neglected diseases

Reliance on market forces can lead to underinvestment in social welfare enhancing innovation. The lack of new medical products in the area of neglected diseases is a case in point. R&D for neglected diseases has increased with new funding and collaborations taking place mainly through product development partnerships (PDPs). PDPs are self-governing, private non-profit R&D organizations. In contrast to push and pull instruments designed to address private-sector R&D underinvestment, PDPs have emerged voluntarily to address this public health challenge. In this study we examine how non-profit R&D collaboration for neglected diseases takes place through PDPs. We find that PDPs act as ‘system integrators' that leverage the resources and capabilities of a network of public, philanthropic and private-sector partners. This paper contributes to an understanding of R&D in a non-profit context and highlights the importance of collaboration and non-market institutions for promoting innovation where market failures occu

A systematic review of behavioral outcomes for leadership interventions among health professionals

Background: Healthcare requires effective leadership to improve patient outcomes, manage change, and achieve organizational goals. Purpose: The purpose of this study was to evaluate interventions aimed at improving leadership behavior in health professionals. Methods: A systematic literature review of key databases (PubMed, CINAHL, Embase, and Scopus) was performed in September 2018. Data were extracted and synthesized. Results: Thirty-three articles from 31 studies met the inclusion criteria. Self-reported leadership behavior showed a significant postprogram improvement. Objective observations were more likely to show improved leadership behavior than subjective observations. Face-to-face delivery of leadership development was more effective than online delivery. Interventions incorporating the elements of personal development planning, self-directed learning, workplace-based learning, and reflection were more likely to develop leadership behavior. Conclusions/implications for practice: Leadership interventions had a beneficial effect on the leadership behaviors of participants based on both subjective and objective changes in behavior. In addition to focusing on individual skill development, interventions that aim to develop leadership should consider the organizational, social, cultural, and political contexts in which behavioral change is expected. Workplace-based learning should be included in program development

Parental evaluation of a telemonitoring service for children with Type 1 Diabetes

Introduction In the past years, we developed a telemonitoring service for young patients affected by Type 1 Diabetes. That service provides data to the clinical staff and offers an important tool to the parents, that are able to oversee in real time their children. The aim of this work was to analyze the parents' perceived usefulness of the service. Methods The service was tested by the parents of 31 children enrolled in a seven-day clinical trial during a summer camp. To study the parents' perception we proposed and analyzed two questionnaires. A baseline questionnaire focused on the daily management and implications of their children's diabetes, while a post-study one measured the perceived benefits of telemonitoring. Questionnaires also included free text comment spaces. Results Analysis of the baseline questionnaires underlined the parents' suffering and fatigue: 51% of total responses showed a negative tendency and the mean value of the perceived quality of life was 64.13 in a 0-100 scale. In the post-study questionnaires about half of the parents believed in a possible improvement adopting telemonitoring. Moreover, the foreseen improvement in quality of life was significant, increasing from 64.13 to 78.39 ( p-value\u2009=\u20090.0001). The analysis of free text comments highlighted an improvement in mood, and parents' commitment was also proved by their willingness to pay for the service (median\u2009=\u2009200\u2009euro/year). Discussion A high number of parents appreciated the telemonitoring service and were confident that it could improve communication with physicians as well as the family's own peace of mind

Prevalence and socio-demographic predictors of food insecurity in Australia during the COVID-19 pandemic

The COVID-19 pandemic has exacerbated economic vulnerabilities and disrupted theAustralian food supply, with potential implications for food insecurity. This study aims to describe theprevalence and socio-demographic associations of food insecurity in Tasmania, Australia, during theCOVID-19 pandemic. A cross-sectional survey (deployed late May to early June 2020) incorporatedthe U.S. Household Food Security Survey Module: Six-Item Short Form, and fifteen demographicand COVID-related income questions. Survey data (n = 1170) were analyzed using univariate andmultivariate binary logistic regression. The prevalence of food insecurity was 26%. The adjusted oddsof food insecurity were higher among respondents with a disability, from a rural area, and living withdependents. Increasing age, a university education, and income above $80,000/year were protectiveagainst food insecurity. Food insecurity more than doubled with a loss of household income above25% (Adjusted Odds Ratio (AOR): 2.02; 95% CI: 1.11, 3.71; p = 0.022), and the odds further increasedwith loss of income above 75% (AOR: 7.14; 95% CI: 2.01, 24.83; p = 0.002). Our results suggest thatthe prevalence of food insecurity may have increased during the COVID-19 pandemic, particularlyamong economically vulnerable households and people who lost income. Policies that supportdisadvantaged households and ensure adequate employment opportunities are important to supportAustralians throughout and post the COVID-19 pandemic

Coring the sedimentary expression of the early Toarcian Oceanic Anoxic Event: New stratigraphic records from the Tethys Ocean

The Toarcian Oceanic Anoxic Event (T-OAE) interval was cored at Colle di Sogno and Gajum in the Lombardy Basin (Southern Alps, northern Italy). The Sogno and Gajum cores recovered 26.83 and 31.18 stratigraphic metres, respectively, of pelagic sediments consisting of marly limestones, marlstone, marly claystone, and black shale. Drilling at both sites resulted in 100\u2009% recovery of unweathered material. The pelagic succession comprises a relatively expanded black shale interval of 4.98\u2009m in the Sogno core and 15.35\u2009m in the Gajum core, with lower and upper boundaries without evidence of hiatuses. The Sogno and Gajum cores can be considered reference sections for the pelagic lower Toarcian interval of the western Tethys and will provide high-resolution micropaleontological, inorganic and organic geochemical, isotopic multiproxy data. Integrated stratigraphy and cyclostratigraphy are predicted to result in estimates of durations and rates to model the ecosystem resilience to the extreme perturbations of the T-OAE and gain a better understanding of current global changes and help provide better projections of future scenarios

The effects of yoga on shoulder and spinal actions for women with breast cancer-related lymphoedema of the arm: A randomised controlled pilot study

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Abstract Background: We aimed to evaluate the effect of an 8-week yoga intervention on the shoulder and spinal actions of women with breast cancer-related arm lymphoedema. Method: A randomised controlled pilot trial. The intervention group (n = 12) completed eight weeks of daily yoga sessions while the control group (n = 11) continued with best current care including information on compression sleeves, skin care, risks of temperature variations and recommended safe use of affected arm. Lumbo-pelvic posture, range of motion (ROM) in the shoulder and spine, and strength in shoulder and pectoral major and minor, and serratus anterior were taken at baseline, week 8 and after a 4-week follow-up. Outcome assessors were blinded to allocation. Results: At week eight the intervention group had an improvement in lumbo-pelvic posture, as indicated by a reduction in pelvic obliquity compared to the control group (mean difference = −8.39°, 95 % CI: −15.64 to −1.13°, p = 0.023). A secondary finding was that strength in shoulder abduction significantly increased following the yoga intervention in both the affected (9.5 kg; CI: 0.34 to 18.66, p = 0.042) and non-affected arm (11.58 kg; CI: 0.25 to 22.91; p = 0.045). There were no significant between group changes in any ROM measures as a result of the yoga intervention. Conclusion: This pilot study demonstrates that participation in yoga may provide benefits for posture and strength in women with Breast Cancer Related Lymphoedema. The improvements may be attributed to the focus of yoga on overall postural and functional movement patterns. Further trials with longer intervention that follow this methodology are warranted. Trial registration: The Australian New Zealand Clinical Trials Registry ACTRN12611000202965. Keywords: Yoga, Arm lymphoedema, Breast cancer, Range of motion, Strength testing Abbreviations: BCRL, Breast cancer related lymphoedema; ROM, Range of motion; QOL, Quality of life; RCT, Randomised controlled trial; BIS, Bioimpedance spectroscopy; LPSI, Left posterior superior iliac spine; RPSI, Right posterior superior iliac spine; LACR, Left acromion; RACR, Right acromio