836 research outputs found

    Manual of therapeutic stomatology. Pt. 2

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    СТОМАТОЛОГИЯ ТЕРАПЕВТИЧЕСКАЯРУКОВОДСТВАИНОСТРАННЫЕ СТУДЕНТЫСТОМАТОЛОГИЯ ЛЕЧЕБНО-ВОССТАНОВИТЕЛЬНАЯСТОМАТОГНАТИЧЕСКИЕ БОЛЕЗНИ /ТЕРАПИЯСТОМАТОЛОГИЯУЧЕБНО-МЕТОДИЧЕСКИЕ ПОСОБИЯВ пособии освещены вопросы лечения стоматологических болезней

    Physical well-being of teachers as a factor in the effectiveness of their professional activities

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    The urgency of the problem in the present study is associated with dramatic changes in the system of contemporary Russian education, which, on the one hand, are positive, and on the other contribute to emotional stress. Teacher, experiencing a state of stress, negatively affects students, transferring their negative emotions and often exerting a negative impact. Even those teachers who try to resist are also prone to burnout and psychosomatic diseases in these conditions. The article is devoted to the identification and analysis of cognitive and emotional changes of teachers, and their correlation with nosological form of cardiovascular disease, identifying the features of psychological, emotional states depending on earlier diagnosis. Mental status of the teacher is reflected in his personality changes in behaviour. The materials are based on the results of studies of physical well-being of teachers and its impact on the quality of the solution of pedagogical tasks. The study was conducted on the basis of the therapeutic department of the polyclinic № 1 in Togliatti. Experimental data confirm that stressful situations characteristic of the educational activities provoke diseases, which are a response to external negative impacts

    Structure of reaction products of some α, β-unsaturated carbonyl compounds with trimethyl phosphite and tri(dimethylamino)phosphine

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    1. Trimethyl phosphite adds to 1,3-diphenyl-5-benzalbarbituric acid at -14°C to give a 1:1 adduct with a bipolar structure, which isomerizes to the methyl ether of the enolic form of the dimethyl ester of α-(1,3-diphenyl-5-barbituryl)benzylphosphonic acid. The latter is also formed when the reaction is run at room temperature. 2. The hydrolysis of the methyl ether of the enolic form of α-(1,3-diphenyl-5-barbituryl)benzylphosphonic acid leads to the formation of the enolic form of the dimethyl ester of α-(1,3-diphenyl-5-barbituryl)·benzylphosphonic acid. 3. The reaction of tri(dimethylamino)phosphine with 1,3-diphenyl-5-benzalbarbituric acid gave the crystalline 1:1 adduct, which had the structure of a bipolar ion containing the P-C bond. 4. The values of the dipole moments, as well as the parameters of the UV spectra, are given for a number of bipolar ions that were obtained using tri(dimethylamino)phosphine. © 1972 Consultants Bureau

    Optical echo in photonic crystals

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    The dynamics of photonic wavepacket in the effective oscillator potential is studied. The oscillator potential is constructed on a base of one dimensional photonic crystal with a period of unit cell adiabatically varied in space. The structure has a locally equidistant discrete spectrum. This leads to an echo effect, i.e. the periodical reconstruction of the packet shape. The effect can be observed in a nonlinear response of the system. Numerical estimations for porous-silicon based structures are presented for femtosecond Ti:Sapphire laser pump.Comment: 4 page

    Crosstalk between Mitochondrial and Sarcoplasmic Reticulum Ca2+ Cycling Modulates Cardiac Pacemaker Cell Automaticity

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    Mitochondria dynamically buffer cytosolic Ca(2+) in cardiac ventricular cells and this affects the Ca(2+) load of the sarcoplasmic reticulum (SR). In sinoatrial-node cells (SANC) the SR generates periodic local, subsarcolemmal Ca(2+) releases (LCRs) that depend upon the SR load and are involved in SANC automaticity: LCRs activate an inward Na(+)-Ca(2+) exchange current to accelerate the diastolic depolarization, prompting the ensemble of surface membrane ion channels to generate the next action potential (AP).To determine if mitochondrial Ca(2+) (Ca(2+) (m)), cytosolic Ca(2+) (Ca(2+) (c))-SR-Ca(2+) crosstalk occurs in single rabbit SANC, and how this may relate to SANC normal automaticity.Inhibition of mitochondrial Ca(2+) influx into (Ru360) or Ca(2+) efflux from (CGP-37157) decreased [Ca(2+)](m) to 80 ± 8% control or increased [Ca(2+)](m) to 119 ± 7% control, respectively. Concurrent with inhibition of mitochondrial Ca(2+) influx or efflux, the SR Ca(2+) load, and LCR size, duration, amplitude and period (imaged via confocal linescan) significantly increased or decreased, respectively. Changes in total ensemble LCR Ca(2+) signal were highly correlated with the change in the SR Ca(2+) load (r(2) = 0.97). Changes in the spontaneous AP cycle length (Ru360, 111 ± 1% control; CGP-37157, 89 ± 2% control) in response to changes in [Ca(2+)](m) were predicted by concurrent changes in LCR period (r(2) = 0.84).A change in SANC Ca(2+) (m) flux translates into a change in the AP firing rate by effecting changes in Ca(2+) (c) and SR Ca(2+) loading, which affects the characteristics of spontaneous SR Ca(2+) release

    УСПЕШНОЕ ЛЕЧЕНИЕ ОБШИРНОГО ГЛУБОКОГО ОЖОГА У РЕБЕНКА С ЕДИНСТВЕННОЙ ЛЕВОЙ ПОЧКОЙ И ОТСУТСТВИЕМ СЕЛЕЗЕНКИ

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    We report a case of successful treatment in a child with extensive deep burns of the trunk and lower limbs with a flame in the absence of the right kidney and spleen.Представлен случай успешного лечения ребенка с обширным глубоким ожогом пламенем туловища и нижних конечностей при отсутствии у пациента правой почки и селезенки

    Evaluation of the efficacy and safety of the hybrid scheme for eradication therapy of Helicobacter pylori infection

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    The aim is to conduct a comprehensive comparative study of the efficacy and safety of the hybrid scheme of eradication therapy (ET) in patients with peptic ulcer of the stomach or duodenum associated with Helicobacter pylori. Materials and methods. In a prospective, randomized comparative study, 180 patients were divided into three equal groups of 60 people, depending on the prescribed 10-day ET regimen. Group 1 - the standard triple scheme (omeprazole, amoxicillin and clarithromycin); group 2 - four-component therapy with preparations of bismuth (omeprazole, tetracycline, metronidazole, bismuth tricalium dicitrate); group 3 - hybrid scheme (first 5 days: omeprazole and amoxicillin, the next 5 days: omeprazole, amoxicillin, clarithromycin, metronidazole). The effectiveness of ET was determined with the help of a breath test a month after the end of therapy. Adverse events were recorded by patients in specially developed diaries. Pharmacoeconomic analysis was carried out using the "cost-effectiveness" method with calculation of the CER coefficient. Results and discussion. The effectiveness of standard triple therapy was 73.3% (ITT), 75.9% (PP); four-component therapy with bismuth preparations - 78.3% (ITT), 82.4% (PP); hybrid scheme - 85% (ITT), 91% (PP). Hybrid therapy proved to be significantly more effective than standard triple therapy with a odds ratio (OR) of 3.25; 95% confidence interval (CI) 1.08-9.73 (p=0.043, χ2=4.75, p-level=0.029298). The incidence of adverse events with the use of triple, four-component and hybrid ET regimens was 15; 18.3 and 28.3% respectively. The OR of at least one adverse event in patients receiving a hybrid ET regimen compared with triple therapy was 2.24 (95% CI 0.91-5.53, p=0.0823, χ2=3.14, p-level=0.076394), and compared with the four-component therapy - 1.76 (95% CI 0.74-4.17, p=0.2804, χ2=1.68, p-level=0.194924). According to the results of the pharmacoeconomic analysis, the most profitable from an economic point of view was a hybrid ET scheme with a CER of 20.1. The conclusion. Hybrid therapy showed the greatest effectiveness in comparison with the triple and four-component ET regimens, however, the incidence of side effects in patients receiving the hybrid ET scheme was higher, although it remained within the acceptable level for use in clinical practice. Pharmacoeconomic analysis also showed the advisability of designating a hybrid ET scheme. The obtained data allow to draw a conclusion about the necessity of further study of the efficiency and safety of the hybrid ET scheme

    Search for the exotic Θ+\Theta^+ resonance in the NOMAD experiment

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    A search for exotic Theta baryon via Theta -> proton +Ks decay mode in the NOMAD muon neutrino DIS data is reported. The special background generation procedure was developed. The proton identification criteria are tuned to maximize the sensitivity to the Theta signal as a function of xF which allows to study the Theta production mechanism. We do not observe any evidence for the Theta state in the NOMAD data. We provide an upper limit on Theta production rate at 90% CL as 2.13 per 1000 of neutrino interactions.Comment: Accepted to European Physics Journal

    Production properties of K*(892) vector mesons and their spin alignment as measured in the NOMAD experiment

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    First measurements of K*(892) mesons production properties and their spin alignment in nu_mu charged current (CC) and neutral current (NC) interactions are presented. The analysis of the full data sample of the NOMAD experiment is performed in different kinematic regions. For K*+ and K*- mesons produced in nu_mu CC interactions and decaying into K0 pi+/- we have found the following yields per event: (2.6 +/- 0.2 (stat.) +/- 0.2 (syst.))% and (1.6 +/- 0.1 (stat.) +/- 0.1 (syst.))% respectively, while for the K*+ and K*- mesons produced in nu NC interactions the corresponding yields per event are: (2.5 +/- 0.3 (stat.) +/- 0.3 (syst.))% and (1.0 +/- 0.3 (stat.) +/- 0.2 (syst.))%. The results obtained for the rho00 parameter, 0.40 +/- 0.06 (stat) +/- 0.03 (syst) and 0.28 +/- 0.07 (stat) +/- 0.03 (syst) for K*+ and K*- produced in nu_mu CC interactions, are compared to theoretical predictions tuned on LEP measurements in e+e- annihilation at the Z0 pole. For K*+ mesons produced in nu NC interactions the measured rho00 parameter is 0.66 +/- 0.10 (stat) +/- 0.05 (syst).Comment: 20 p
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