100 research outputs found

    Séminaire collectif du Groupe de recherches sur les missions religieuses dans le monde ibérique moderne

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    Pierre-Antoine Fabre et Bernard Vincent, directeurs d’études Compte rendu non communiquĂ©

    Séminaire du groupe collectif du Groupe de recherches sur les missions religieuses dans le monde ibérique moderne

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    Bernard Vincent et Pierre-Antoine Fabre, directeurs d’étudesJean-Paul Zuñiga, maĂźtre de confĂ©rences Ă  l’UniversitĂ© de Reims Le sĂ©minaire du Groupe de recherches a poursuivi cette annĂ©e dans la voie qu’il s’est tracĂ©e : la prĂ©sentation de divers domaines dans lesquels s’inscrit le phĂ©nomĂšne missionnaire Ă  l’époque moderne et contemporaine. Ce sĂ©minaire vise ainsi d’une part Ă  situer l’histoire religieuse (dans ses dimensions institutionnelle, culturelle, spirituelle, rituelle) dans des cadres ..

    Séminaire collectif du Groupe de recherches sur les missions religieuses dans le monde ibérique moderne

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    Bernard Vincent et Pierre-Antoine Fabre, directeurs d’étudesJean-Paul Zuñiga, maĂźtre de confĂ©rences Ă  l’UniversitĂ© de Reims Cette annĂ©e le sĂ©minaire s’est organisĂ© pour l’essentiel autour des recherches personnelles des membres du groupe ainsi que de l’enquĂȘte collective en cours sur les lettres de demande de dĂ©part en mission des jeunes jĂ©suites aux XVIe et XVIIe siĂšcles (Indipetae). Les questions abordĂ©es ont cependant Ă©tĂ© axĂ©es autour de deux grands thĂšmes : la confrontation entre les fond..

    Séminaire collectif du Groupe de recherches sur les missions religieuses dans le monde ibérique moderne

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    Bernard Vincent et Pierre-Antoine Fabre, directeurs d’étudesJean-Paul Zuñiga, maĂźtre de confĂ©rences Compte rendu non communiquĂ©. Bernard Vincent, Jean-FrĂ©dĂ©ric Schaub, Wolfgang Kaiser, directeurs d’étudesJordi Canal, Enric Porqueres i GenĂ©, Jean-Paul Zuñiga, maĂźtres de confĂ©rences Histoire et anthropologie du monde hispanique Compte rendu non communiquĂ©

    Mycobacterium tuberculosis Complex Mycobacteria as Amoeba-Resistant Organisms

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    International audienceBackground: Most environmental non-tuberculous mycobacteria have been demonstrated to invade amoebal trophozoites and cysts, but such relationships are largely unknown for members of the Mycobacterium tuberculosis complex. An environmental source has been proposed for the animal Mycobacterium bovis and the human Mycobacterium canettii.Methodology/Principal Findings: Using optic and electron microscopy and co-culture methods, we observed that 89±0.6% of M. canettii, 12.4±0.3% of M. tuberculosis, 11.7±2% of M. bovis and 11.2±0.5% of Mycobacterium avium control organisms were phagocytized by Acanthamoeba polyphaga, a ratio significantly higher for M. canettii (P = 0.03), correlating with the significantly larger size of M. canetti organisms (P = 0.035). The percentage of intraamoebal mycobacteria surviving into cytoplasmic vacuoles was 32±2% for M. canettii, 26±1% for M. tuberculosis, 28±2% for M. bovis and 36±2% for M. avium (P = 0.57). M. tuberculosis, M. bovis and M. avium mycobacteria were further entrapped within the double wall of <1% amoebal cysts, but no M. canettii organisms were observed in amoebal cysts. The number of intracystic mycobacteria was significantly (P = 10−6) higher for M. avium than for the M. tuberculosis complex, and sub-culturing intracystic mycobacteria yielded significantly more (P = 0.02) M. avium organisms (34×104 CFU/mL) than M. tuberculosis (42×101 CFU/mL) and M. bovis (35×101 CFU/mL) in the presence of a washing fluid free of mycobacteria. Mycobacteria survived in the cysts for up to 18 days and cysts protected M. tuberculosis organisms against mycobactericidal 5 mg/mL streptomycin and 2.5% glutaraldehyde.Conclusions/Significance: These data indicate that M. tuberculosis complex organisms are amoeba-resistant organisms, as previously demonstrated for non-tuberculous, environmental mycobacteria. Intercystic survival of tuberculous mycobacteria, except for M. canettii, protect them against biocides and could play a role in their life cycle

    COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

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    Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≀ 18 years: 69, 48, 23; 85%), older adults (≄ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P &lt; 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

    Introduction

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    Brice Catherine, Fabre Pierre-Antoine, Vincent Bernard. Introduction. In: MĂ©langes de l'École française de Rome. Italie et MĂ©diterranĂ©e, tome 111, n°1. 1999. pp. 201-202

    Introduction

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    Brice Catherine, Fabre Pierre-Antoine, Vincent Bernard. Introduction. In: MĂ©langes de l'École française de Rome. Italie et MĂ©diterranĂ©e, tome 111, n°1. 1999. pp. 201-202

    Symptoms of degradation in a tropical rock glacier (Andes of Bolivia, 21°S).

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