Comparison of knee sonography and pressure pain threshold after anterior cruciate ligament reconstruction with quadriceps tendon versus hamstring tendon autografts in soccer players

Objective: The aim of this study was to compare the pressure pain threshold and muscle architecture after an anatomic single bundle reconstruction with quadriceps tendon and hamstring tendon autografts of the anterior cruciate ligament in competitive soccer players. We hypothesized that both procedures will obtain similar outcomes. Methods: Fifty-one participants were enrolled in this secondary analysis of a randomized controlled trial and were categorised into two groups: quadriceps tendon (QT) group (23 men and 3 women; mean age 18.7 ± 3.6; BMI 23.0 ± 2.2) or hamstring tendon (HT) group (16 men and 9 women; mean age 19.2 ± 3.6 BMI 23.5 ± 3.5). Both groups followed the same rehabilitation staged protocol. Pressure pain threshold (PPT), as a measure of perceived pain, was obtained in several points of quadriceps and hamstring muscles. Ultrasound imaging measurements were obtained in quadriceps tendon and knee cartilage thickness. Four measurements were taken in this study: baseline, 1, 3, 6, and 12 months after the anterior cruciate ligament (ACL) reconstruction. Results: The analysis of PPT did not find significant differences in both groups x interaction time in the points evaluated: epicondyle (QT = 421.1 ± 184.1 vs HT = 384.7 ± 154.1 kPa), vastus lateralis (QT = 576.2 ± 221.3 vs HT = 560.1 ± 167.7 kPa), vastus medialis (QT = 544.7 ± 198.8 vs HT = 541.1.1 ± 181.77 kPa), patellar tendon (QT = 626.3 ± 221.1 vs HT = 665.0 ± 205.5 kPa), QT (QT = 651.1 ± 276.9 vs HT = 660.0 ± 195.2 kPa). (QT = 667.8 ± 284.7 vs HT = 648.2 ± 193.4 kPa) injured knee (all P > 0.05). The results of ultrasound imaging did not show significant differences in both groups interaction time in the thickness of the QT (QT = 9.9 ± 2.4 vs HT = 9.4 ± 1.7 kPa) and patellar cartilage (QT = 3.2 ± 0.6 vs HT = 3.2 ± 0.4 kPa) (P > 0.05). Conclusion: A QT autograft produces similar results to a HT autograft in ACL reconstructions in terms of pressure pain threshold and ultrasound muscle architecture during the 1-year follow-up. Level of Evidence: Level I, Therapeutic Study

Effect of moisture and oil content in the supercritical CO2 defatting of hermetia illucens larvae

The supercritical defatting of H. illucens was scaled up at 450 bar and 60 ◦C from a 270 cm3 extraction cell to a vessel five times larger. Then, eight different H. illucens larvae batches, with vari able content of oil (16.80–29.17% w/w) and moisture (4.45–15.95% w/w) were defatted. The effect of these parameters on yield and oil composition was analyzed. The presence of moisture in the larvae batch, in the range of the values studied, had no negative effect on the oil recovery efficiency, which was mainly determined by the initial content of oil in the larvae samples. Furthermore, no differences were determined in the fatty acid profile of the oils recovered, which were rich in satu rated fatty acids, mainly lauric acid (ca. 50% w/w). Minor lipids, such as squalene and phytosterols, were determined in all the oil samples. The moisture content in the oils extracted was in the range of 0.118–1.706% w/w. Therefore, some samples exceeded the limits recommended for volatile matter in edible fats and oils (0.2%, including moisture). Yet, concerning the oil peroxide index, values were much lower than those corresponding to the oil extracted using hexan

Calculation of Response matrix of a BSS with 6LiI scintillator

The response matrix of a Bonner sphere spectrometer was calculated using MCNP 4C and MCNPX 2.4.0 codes. As thermal neutron detector a 0.4 cm £; 0.4 cm 6LiI which is located at the center of a set of polyethylene spheres. The response was calculated for 0, 2, 3, 5, 8, 10, and 12 inches-diameter polyethylene spheres for neutrons whose energy goes from 2.50E(-8) to 100 MeV. The response matrix was calculated for 23 neutron energies, the response functions were energy-interpolated to 51 neutron energies and were compared with a matrix response reported in the literature, in this comparison both response matrices are in agreement. The main differences were found in the bare detector and are attributed to the irradiation conditions and cross sections, for the other detectors the differences are due to the cross sections libraries

Investigating prehistoric diet and lifeways of early farmers in central northern Spain (3000-1500 CAL BC) using stable isotope techniques

This work focuses on reconstructing past diets and animal management during Prehistory in Central Northern Spain, spanning the NE area of the Old Castilian Plateau to the Cantabrian coast, from c. 3000-1500 BCE. During this time, early farming communities made changes in their models of production and social reproduction that crystallised in the emergence of social complexity. To investigate these changes, we reconstructed the past diet of these early farming populations by using stable isotope analysis (?13C, ?15N, ?34S) of human and animal remains from the recently excavated sites of Abrigo de la Castañera in Cantabria and Arroyal I, El Hornazo, Fuente Celada and Ferrocarril-La Dehesa in Burgos. The human remains derived from a range of burial contexts including pit graves, megalithic monuments and burial caves. To provide initial insights into animal management during this timeframe, associated faunal remains were also studied as a baseline. In total, 52 samples were analysed, including 17 human burials and 35 animal specimens (cattle, sheep, pig, red deer and dog). Results show that humans in these sites consumed relatively similar diets, comprising of a predominantly C3 diet including animal protein. Animal management patterns indicate a wider use of the landscape for herbivore grazing. The differing diets of dogs at El Hornazo provide insights into the relationship that they had with humans and tentatively suggests differences in the diet of working animals versus household pets. The ?34S values of two individuals from Arroyal I indicate that they came from different regions, implying a level of inland mobility during the Chalcolithic

Medidor multicota para piezas producidas por máquinas-herramienta

Referencia OEPM: P9600748.-- Fecha de solicitud: 28/03/1996.-- Titular: Consejo Superior de Investigaciones Científicas (CSIC).El medidor multicota para piezas producidas por máquinas-herramienta es un sistema que permite medir simultáneamente hasta 16 cotas en piezas producidas por máquinas-herramienta, visualizando sobre una pantalla de ordenador los resultados en forma analógica sobre una columna, con indicación de límites de tendencia y tolerancia, y digital sobre un indicador numérico. Consta de un multiplexor analógico (1, ver figura en archivo de texto completo) cuya salida se entrega a un amplificador (6) que junto con el divisor programable (8) y el conversor analógico/digital (7), proporciona la medida del canal seleccionado (5). Un circuito temporizador (10 y 11) facilita la realización de medidas promediadas y a intervalos regulares. Dispone de salidas de control (22) indicadoras de: pieza fuera de tolerancia, corrección paralela o cónica, positiva o negativa, cambio o regeneración de herramienta y situación de alarma (15 a 21). La presencia de pieza puede detectarse automáticamente o bajo comando (14). Dispone de amplias facilidades de programación y calibrado, para ser utilizado con una gran diversidad de sensores y aplicaciones.Peer reviewe

The interaction of slaughtering, drying, and defatting methods differently affects oxidative quality of the fat from black soldier fly (Hermetia illucens) larvae

The interrelation effect of slaughtering, drying, and defatting methods of BSFL on the oxidative quality of the derived fat was studied. Blanching and freezing were compared as slaughtering methods, followed by oven or freeze-drying for drying and mechanical pressing or SFE for defatting. The oxidative state and stability of the extracted fat and defatted meals were monitored immediately after their production, using peroxide value (PV) and Rancimat test, and over 24 weeks of storage. Slaughtering and drying methods had an independent effect on PV, with freezing and freeze-drying being the best methods. Mechanical pressing and SFE were comparable and superior to conventional hexane defatting. Interactions were observed between slaughtering and defatting, drying and defatting, and between all three factors. Generally, freeze-drying combined with any of the slaughtering and defatting methods resulted in the lowest PVs, with mechanical pressing being preferred. Freeze-drying plus mechanical pressing also produced the most stable fats during storage according to the evolution of PV, while the combination of blanching and SFE produced the least stable. A significant correlation was found between the PV at 24 weeks and the antioxidant activity of the fats. Contrary to storage assays, in accelerated Rancimat assays, freeze-dried samples were the least stable, which was partially attributed to the significant correlation with the acid values of the samples. Defatted meals followed a similar pattern to the extracted fat, except for worse oxidation for SFE defatting. Therefore, the different processing methods of slaughtering, drying, and defatting of BSFL differently affect lipid oxidation, with interactions between such successive stepsThis research was funded by the Spanish National Plans of Aquaculture of the Ministry of Agriculture, Fisheries and Food, project ACUINSECT (Optimization of insect flours as sustainable ingredient for aquaculture fee

Efectividad de 5-fluoruracilo y vinorelbina en pacientes multitratadas por cáncer de mama metastásico

Objetivo. Evaluar la actividad y toxicidad de fluoruracilo en infusión continua y vinorelbina en segunda o tercera línea de tratamiento del cáncer de mama metastásico (CMM). Método y pacientes. En este estudio fase II se incluyeron 24 pacientes que habían recibido doxorrubicina y/o paclitaxel. Se administró 5-fluoruracilo a 1g/m2/día en infusión continua por 3 días y vinorelbina a 30 mg/m2 D1 cada 21 días por 6 ciclos. Resultados. Las respuestas globales observadas fueron del 37,5% (12,5% respuestas completas). El período libre de enfermedad se calculó una media de 6,33 ± 8,12 meses (IC 95% de 3,43 meses). Se observó toxicidad en el 12,5% de las pacientes y no se registró toxicidad grave ni muertes relacionadas a tratamiento. Conclusión. El 5-fluoruracilo/vinorelbina a las dosis administradas es un esquema efectivo en pacientes con CMM multitratadas, con un bajo perfil de toxicidad y costo

Buenas prácticas en la gestión de capital de trabajo y su impacto en la creación de valor en las empresas representativas del sector industrial y minero de la bolsa de valores de Lima durante el periodo 2010-2016

El presente estudio tiene como propósito dar conocer las Buenas Prácticas en la gestión de capital de trabajo de las principales empresas mineras que cotizan en la Bolsa de Valores de Lima. En este trabajo se presentan los resultados de un estudio descriptivo, cuyo objetivo es identificar las prácticas que estas utilizan y su impacto en la creación de valor durante el periodo 2010-2016. Para este fin se seleccionaron a cuatro empresas del sector minero mediante la aplicación de criterios. En Perú aún no existen prácticas financieras estandarizadas que sirvan como base en las empresas del sector. Por lo tanto, surge la necesidad de realizar una investigación que identifique las buenas prácticas en el sector minero. En el marco de las empresas, está enfocado en identificar las buenas prácticas de las cuatro empresas mineras y analizar a través de este trabajo de investigación si existe relación entre la gestión de capital de trabajo y la creación de valor. Para este fin se realizaron entrevistas a representantes de cada empresa para luego ser conjuntamente usado con el análisis e interpretación de los resultados y así poder responder a las preguntas del presente trabajo. Los resultados de la investigación mostraron que las empresas utilizan más de una metodología para medir la creación de valor de su empresa y realizan diferentes gestiones productivas respecto al capital de trabajo, entre las cuales: (a) reducción/ eficiencia de costos operativos, (b) diversificación de fuentes de financiamiento, y (c) estrategias logísticas de optimización de tiempos.The present work has as purpose to present the Good Practices in the management of working capital of the main mining companies listed on the Stock Exchange of Lima. This paper presents the results of a descriptive study, whose objective is to identify the practices they use and their impact on the creation of value during the period 2010-2016, for this purpose four companies in the sector were selected through different filters miner. In Peru, there are still no standardized financial practices that serve as a basis for companies in the sector. Therefore, there is a need to carry out research that identifies good practices in the mining sector. In the framework of the business, it is focused on identifying the good practices of the four mining companies and demonstrating through this research work if there is a relationship between the management of working capital and the creation of value. For this purpose, interviews were held with representatives of each company to later be jointly used with the analysis and interpretation of the results and thus be able to answer the questions of the present work. The results of the research showed that companies use more than one methodology to measure the value creation of their company and carry out different productive managements with respect to working capital, among which: (a) reduction / efficiency of operating costs, (b) diversification of funding sources and, (c) time optimization logistics strategies.Tesi