MOTIVACIÓN Y SU INFLUENCIA EN EL DESEMPEÑO LABORAL DE LA EMPRESA D’LABORUM PLUS S.A.C. SEDE CHICLAYO 2018

Las empresas, sobre todo las prestadoras de servicios, deben tener en cuenta que, sus trabajadores muchas veces son el primer o único contacto del cliente con la organización, por lo que, para mantener a sus clientes satisfechos o al menos complacidos con la atención, los trabajadores deben desenvolverse de la manera más adecuada, si tomamos en cuenta que cada persona tiene problemas personales que influyen en su desempeño laboral, la empresa entonces debe encontrar la manera de motivar a sus trabajadores para que desarrollen sus capacidades al máximo y esto a su vez se vea reflejado en un mejor desempeño laboral. Entonces, es ahí cuando las herramientas más eficaces de automotivación por parte de los trabajadores y de motivación por parte de los directivos se convierten en asuntos de gran interés; en la empresa D’LABORUM PLUS, no existe variedad de políticas o estrategias para incentivar a sus trabajadores de diferentes formas, situación que me incentivó a escoger esta empresa y conocer cuál es el nivel de motivación que tienen los trabajadores al momento de realizar su trabajo, ya que hoy en día la motivación es muy importante para todos los trabajadores de la empresa. La investigación es de tipo descriptiva correlacional, para lo cual se utilizó la técnica encuestas y como instrumento el cuestionario para la recolección de los datos, una vez que los datos fueron codificados, se transfirieron a una matriz, guardado en un archivo y limpiado los errores, luego el investigador procedió a analizarlos por medio de programas computacionales como el SPSS, para finalmente presentar los resultados en tablas y gráficos e interpretarlos. Finalmente la presente investigación al ser de tipo correlacional, se aplicaron cuestionarios de 30 preguntas a un total de 35 personas, utilizando la escala Likert, luego mediante el software estadístico SPSS V21 se efectuó la tabulación de datos y se utilizó el coeficiente de correlación de Pearson obteniendo el valor de 0.909 con un margen de error del 0.0001 lo cual es significativo con una correlación muy fuerte; por tal motivo se rechaza la hipótesis Ho y se acepta la hipótesis H1 es decir que existe relación entre ambas variables, cumpliendo el tercer objetivo al demostrar que existe relación entre la motivación y su influencia sobre el desempeño laboral de los trabajadores de la empresa D’LABORUM PLUS.Tesi

Gestión administrativa y atención al cliente en una oficina descentralizada de distribución eléctrica en la provincia de Chiclayo

El objetivo general fue determinar la relación que existe entre la gestión administrativa y la atención al cliente en una oficina descentralizada de distribución eléctrica en la provincia de Chiclayo. La tesis fue cuantitativa con un nivel correlacional, se utilizó una población de 20 colaboradores que respondieron cuestionarios validados y confiables en base a preguntas cerradas con escala de Likert. La tesis concluye que la mejora de las actividades de la gestión administrativa, impactan medianamente en la calidad de atención que se brindan a los usuarios, puesto que la gestión administrativa, se encuentra orientada a la consecución de aspectos más estratégicos que cumplir con indicadores de atención al usuario. Con respecto al nivel de gestión administrativa en una oficina descentralizada de distribución eléctrica en la provincia de Chiclayo. El 50% de los colaboradores encuentra un nivel alto en la variable gestión administrativa, mientras que un 40% encuentra un nivel medio y un 10% encuentra un nivel bajo. De los resultados se logra evidenciar que la gran mayoría de los colaboradores conoce la misión y visión de la organización, mostrándose de acuerdo que existen indicadores para medir la calidad de atención

In vivo antimicrobial activity of silver nanoparticles produced via a green chemistry synthesis using Acacia rigidula as a reducing and capping agent

Introduction: One of the main issues in the medical field and clinical practice is the development of novel and effective treatments against infections caused by antibiotic-resistant bacteria. One avenue that has been approached to develop effective antimicrobials is the use of silver nanoparticles (Ag-NPs), since they have been found to exhibit an efficient and wide spectrum of antimicrobial properties. Among the main drawbacks of using Ag-NPs are their potential cytotoxicity against eukaryotic cells and the latent environmental toxicity of their synthesis methods. Therefore, diverse green synthesis methods, which involve the use of environmentally friendly plant extracts as reductive and capping agents, have become attractive to synthesize Ag-NPs that exhibit antimicrobial effects against resistant bacteria at concentrations below toxicity thresholds for eukaryotic cells. Purpose: In this study, we report a green one-pot synthesis method that uses Acacia rigidula extract as a reducing and capping agent, to produce Ag-NPs with applications as therapeutic agents to treat infections in vivo. Materials and methods: The Ag-NPs were characterized using transmission electron microscopy (TEM), high-resolution TEM, selected area electron diffraction, energy-dispersive spectroscopy, ultraviolet–visible, and Fourier transform infrared. Results: We show that Ag-NPs are spherical with a narrow size distribution. The Ag-NPs show antimicrobial activities in vitro against Gram-negative (Escherichia coli, Pseudomonas aeruginosa, and a clinical multidrug-resistant strain of P. aeruginosa) and Gram-positive (Bacillus subtilis) bacteria. Moreover, antimicrobial effects of the Ag-NPs, against a resistant P. aeruginosa clinical strain, were tested in a murine skin infection model. The results demonstrate that the Ag-NPs reported in this work are capable of eradicating pathogenic resistant bacteria in an infection in vivo. In addition, skin, liver, and kidney damage profiles were monitored in the murine infection model, and the results demonstrate that Ag-NPs can be used safely as therapeutic agents in animal models. Conclusion: Together, these results suggest the potential use of Ag-NPs, synthesized by green chemistry methods, as therapeutic agents against infections caused by resistant and nonresistant strains. Keywords: silver nanoparticles, green synthesis, in vitro antibacterial activity, in vivo antibacterial activity, skin infection, toxicological stud

Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK‐air®

Background: MASK-air® is an app that supports allergic rhinitis patients in disease control. Users register daily allergy symptoms and their impact on activities using visual analog scales (VASs). We aimed to assess the concurrent validity, reliability, and responsiveness of these daily VASs. Methods: Daily monitoring VAS data were assessed in MASK-air® users with allergic rhinitis. Concurrent validity was assessed by correlating daily VAS values with those of the EuroQol-5 Dimensions (EQ-5D) VAS, the Control of Allergic Rhinitis and Asthma Test (CARAT) score, and the Work Productivity and Activity Impairment Allergic Specific (WPAI-AS) Questionnaire (work and activity impairment scores). Intra-rater reliability was assessed in users providing multiple daily VASs within the same day. Test–retest reliability was tested in clinically stable users, as defined by the EQ-5D VAS, CARAT, or “VAS Work” (i.e., VAS assessing the impact of allergy on work). Responsiveness was determined in users with two consecutive measurements of EQ-5D-VAS or “VAS Work” indicating clinical change. Results: A total of 17,780 MASK-air® users, with 317,176 VAS days, were assessed. Concurrent validity was moderate–high (Spearman correlation coefficient range: 0.437–0.716). Intra-rater reliability intraclass correlation coefficients (ICCs) ranged between 0.870 (VAS assessing global allergy symptoms) and 0.937 (VAS assessing allergy symptoms on sleep). Test–retest reliability ICCs ranged between 0.604 and 0.878—“VAS Work” and “VAS asthma” presented the highest ICCs. Moderate/large responsiveness effect sizes were observed—the sleep VAS was associated with lower responsiveness, while the global allergy symptoms VAS demonstrated higher responsiveness. Conclusion: In MASK-air®, daily monitoring VASs have high intra-rater reliability and moderate–high validity, reliability, and responsiveness, pointing to a reliable measure of symptom loads

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK-air (R)

Background MASK-air (R) is an app that supports allergic rhinitis patients in disease control. Users register daily allergy symptoms and their impact on activities using visual analog scales (VASs). We aimed to assess the concurrent validity, reliability, and responsiveness of these daily VASs. Methods Daily monitoring VAS data were assessed in MASK-air (R) users with allergic rhinitis. Concurrent validity was assessed by correlating daily VAS values with those of the EuroQol-5 Dimensions (EQ-5D) VAS, the Control of Allergic Rhinitis and Asthma Test (CARAT) score, and the Work Productivity and Activity Impairment Allergic Specific (WPAI-AS) Questionnaire (work and activity impairment scores). Intra-rater reliability was assessed in users providing multiple daily VASs within the same day. Test-retest reliability was tested in clinically stable users, as defined by the EQ-5D VAS, CARAT, or "VAS Work" (i.e., VAS assessing the impact of allergy on work). Responsiveness was determined in users with two consecutive measurements of EQ-5D-VAS or "VAS Work" indicating clinical change. Results A total of 17,780 MASK-air (R) users, with 317,176 VAS days, were assessed. Concurrent validity was moderate-high (Spearman correlation coefficient range: 0.437-0.716). Intra-rater reliability intraclass correlation coefficients (ICCs) ranged between 0.870 (VAS assessing global allergy symptoms) and 0.937 (VAS assessing allergy symptoms on sleep). Test-retest reliability ICCs ranged between 0.604 and 0.878-"VAS Work" and "VAS asthma" presented the highest ICCs. Moderate/large responsiveness effect sizes were observed-the sleep VAS was associated with lower responsiveness, while the global allergy symptoms VAS demonstrated higher responsiveness. Conclusion In MASK-air (R), daily monitoring VASs have high intra-rater reliability and moderate-high validity, reliability, and responsiveness, pointing to a reliable measure of symptom loads.</p

re-habitar El Carmen : Un proyecto sobre patrimonio contemporáneo

El proyecto _re-HABITAR suponía para el propio proceder de la institución un avance más allá del reconocimiento, registro, inventario o protección patrimonial de la arquitectura del siglo XX y del Movimiento Moderno para posicionarse en la acción preventiva y conservativa de ese legado contemporáneo. Para ello, la praxis patrimonial se aferraba a un modelo: el de la vivienda social en España en la segunda mitad del siglo XX; a un caso concreto: el de la barriada de Nuestra Señora del Carmen (Recasens Méndez-Queipo de Llano, 1958); y a un requisito fundamental: analizar un objeto vivo y en uso, aún con la presencia de quienes lo vivieron y usaron desde su origen

Evidence of spatial clustering of childhood acute lymphoblastic leukemia cases in Greater Mexico City: report from the Mexican Inter-Institutional Group for the identification of the causes of childhood leukemia

BackgroundA heterogeneous geographic distribution of childhood acute lymphoblastic leukemia (ALL) cases has been described, possibly, related to the presence of different environmental factors. The aim of the present study was to explore the geographical distribution of childhood ALL cases in Greater Mexico City (GMC).MethodsA population-based case-control study was conducted. Children &lt;18 years old, newly diagnosed with ALL and residents of GMC were included. Controls were patients without leukemia recruited from second-level public hospitals, frequency-matched by sex, age, and health institution with the cases. The residence address where the patients lived during the last year before diagnosis (cases) or the interview (controls) was used for geolocation. Kulldorff’s spatial scan statistic was used to detect spatial clusters (SCs). Relative risks (RR), associated p-value and number of cases included for each cluster were obtained.ResultsA total of 1054 cases with ALL were analyzed. Of these, 408 (38.7%) were distributed across eight SCs detected. A relative risk of 1.61 (p&lt;0.0001) was observed for the main cluster. Similar results were noted for the remaining seven ones. Additionally, a proximity between SCs, electrical installations and petrochemical facilities was observed.ConclusionsThe identification of SCs in certain regions of GMC suggest the possible role of environmental factors in the etiology of childhood ALL

NIVEL DE MOTIVACIÓN EN UNA EMPRESA DE TERCERIZACION DE SERVICIOS - CHICLAYO 2018

Trabajo de investigaciónLa investigación es de tipo descriptiva, para lo cual se utilizó la técnica encuestas y como instrumento el cuestionario para la recolección de los datos; así mismo la investigación como objetivo demostrar la importancia de la aplicación de factores de motivación para mejorar el clima laboral en una empresa de servicios, obteniendo como resultado que la empresa en estudio mantenga un nivel alto en motivación debido a un buen manejo en los factores motivacionales

Nivel de motivación en una empresa de tercerizacion de servicios - Chiclayo 2018

La investigación es de tipo descriptiva, para lo cual se utilizó la técnica encuestas y como instrumento el cuestionario para la recolección de los datos; así mismo la investigación como objetivo demostrar la importancia de la aplicación de factores de motivación para mejorar el clima laboral en una empresa de servicios, obteniendo como resultado que la empresa en estudio mantenga un nivel alto en motivación debido a un buen manejo en los factores motivacionales.Trabajo de investigació