A abordagem das micro-credenciais no ensino superior

The changes generated by the third and fourth industrial revolution in all sectors of society also impact the educational ecosystems, especially tertiary education, which, after assuming a more active role in the economic development of nations, has adopted new dynamics in its system based on the generation of lifelong learning and the design of personalized and non-linear learning paths that benefit employability. The purpose of this article is to explore the micro-credentialing approach as a complementary strategic trend in university programs that favors the new dynamics in demand. First, a literature review is carried out to take a look at the origin of this strategy, its characteristics, conditions, methodology, criticisms, projections and recommendations. Then, some good practices led by universities worldwide and locally concerning its use are described, and finally, the potential of the ucc to include microcredentialing in its learning pathways is detailed. The analysis shows that, despite the lack of unified regulatory policies, the strategy has been widely deployed, especially in Europe and North America, and that Colombia has joined the Latin American countries that have seen in it an opportunity to serve a wider training public and stimulate demand for their academic programs. This constitutes an opportunity for the ucc, which has sufficient theoretical, institutional, and methodological inputs to implement it because it fits perfectly with its institutional vision.Los cambios generados por la tercera y cuarta revolución industrial en todos los sectores de la sociedad impactan también los ecosistemas educativos, especialmente a la educación terciaria que, tras asumir un rol más activo frente al desarrollo económico de las naciones, ha adoptado nuevas dinámicas en su sistema, que se basan en la generación de aprendizaje a lo largo de toda la vida y en el diseño de rutas de aprendizaje personalizadas y no lineales que beneficien la empleabilidad. El propósito de este artículo es explorar el enfoque de la microcredencialización como tendencia estratégica complementaria de los programas universitarios que favorece las nuevas dinámicas demandadas. Primero, se realiza un rastreo bibliográfico para dar una mirada al origen de esta estrategia, a sus características, condiciones, metodología, críticas, proyecciones y recomendaciones. Luego, se describen algunas buenas prácticas lideradas por universidades a nivel mundial y local concernientes a su uso y, finalmente, se detallan las potencialidades que tiene la ucc para incluir la microcredencialización en sus rutas de aprendizaje. El análisis muestra que, a pesar de la falta de políticas unificadas reguladoras, la estrategia ha tenido un amplio despliegue especialmente en Europa y América del Norte y que Colombia se ha sumado a los países latinoamericanos que han visto en ella una oportunidad para atender un público en formación más amplio y estimular la demanda de sus programas académicos. Esto constituye una oportunidad para la ucc, que cuenta con los insumos teóricos, institucionales y metodológicos suficientes para implementarlo porque se ajusta perfectamente a su visión institucional.Los cambios generados por la tercera y cuarta revolución industrial en todos los sectores de la sociedad impactan también los ecosistemas educativos, especialmente a la educación terciaria que tras asumir un rol más activo frente al desarrollo económico de las naciones ha debido asumir nuevas dinámicas en su sistema basadas en la generación de aprendizaje a lo largo de toda la vida, la formación del talento humano competente que se requiere para atender las demandas del cambiante mercado laboral y el diseño de rutas de aprendizaje flexibles, personalizadas y no lineales que beneficien la empleabilidad. El propósito de este artículo es explorar el enfoque de la microcredencialización como tendencia estratégica complementaria de los programas universitarios que favorece las nuevas dinámicas demandadas, dando una mirada a su origen, características, condiciones, metodología, críticas y balances de implementación. El informe deja ver que, a pesar de la falta de políticas unificadas reguladoras, la estrategia ha tenido un amplio despliegue especialmente en Europa y América del Norte, y que Colombia se ha sumado a los países latinoamericanos que han visto en ella una oportunidad para generar un impacto social más inmediato, atender un público en formación más amplificado y estimular sus programas académicos a través de la generación de itinerarios flexibles y el otorgamiento de insignias digitales. La Universidad Cooperativa de Colombia aún no implementa este enfoque, pero cuenta con los insumos suficientes para hacerlo.As mudanças geradas pela terceira e quarta revolução industrial em todos os setores da sociedade impactam também os ecossistemas educativos, especialmente o ensino superior que, após assumir um papel mais ativo no desenvolvimento económico das nações, adotou novas dinâmicas no seu sistema baseadas na geração de aprendizagem ao longo da vida e no desenho de percursos de aprendizagem personalizados e não lineares que beneficiam a empregabilidade. O objetivo deste artigo é explorar a abordagem da micro-credenciação como uma tendência estratégica complementar nos programas universitários que favorece as novas dinâmicas em curso. Em primeiro lugar, é feita uma revisão da literatura para analisar a origem desta estratégia, as suas características, condições, metodologia, críticas, projecções e recomendações. Em seguida, descrevem-se algumas boas práticas lideradas por universidades a nível mundial e local relativamente à sua utilização e, por último, detalha-se o potencial da UCC para incluir a microcredenciação nos seus percursos de aprendizagem. A análise mostra que, apesar da falta de políticas reguladoras unificadas, a estratégia foi amplamente implantada, especialmente na Europa e na América do Norte, e que a Colômbia se juntou aos países latino-americanos que viram nela uma oportunidade de servir um público de formação mais vasto e estimular a procura dos seus programas académicos. Trata-se de uma oportunidade para a UCC, que dispõe de suficientes contributos teóricos, institucionais e metodológicos para a sua implementação, uma vez que se enquadra perfeitamente na sua visão institucional

Efecto de la manipulación del semen criopreservado de bovinos Bos Taurus sobre la integridad espermática

This study evaluated the semen thawing and application effect in 33 bovine cattle farms in the Colombian Magdalena Medio region and studied in vitro, the injury effect found on the integrity of sperm membranes. The information was collected in farms by a specific paper form, The in vitro study was carried out in the Reproductive Animal Biotechnology laboratory at the Instituto Universitario de la Paz (Barrancabermeja, Santander, Colombia). The study consisted of exposing commercial 0.5 ml straws of bull Holstein and Brown Swiss to the conventional technique, and three modifications thereof (injuries) by a randomized design. None of the farms evaluated applied correctly the practice of artificial insemination. Evident errors were: Time excess for extraction of the straw, thawing in the axillary region and incorrect combination of time and temperature. The results showed significant difference (P <0.05) by the race effect for the integrity and strength of the plasma membrane, also for the integrity ofthe membranes by treatment effect, when the straw was thawed at body temperature in the axillary region and for the integrity of the acrosomal membrane when extraction straw was performed incorrectly. Holstein semen evidences a slight tendency to be more resistant than the Brown Swiss breed.En el estudio se evaluó el efecto de descongelar y aplicar semen de bovinos Bos Taurus en 33 ganaderías del Magdalena Medio colombiano, y se estudió in vitro el efecto de la injuria encontrada sobre la integridad de las membranas espermáticas. La información en fincas se recopiló mediante formulario específico, mientras que el estudio in vitro se ejecutó en el laboratorio de Biotecnología Reproductiva Animal del Instituto Universitario de la Paz (Barrancabermeja, Santander). El estudio consistió en someter pajillas comerciales de 0.5 ml de toros Holstein y Pardo Suizo a la técnica convencional y a tres modificaciones de esta (injurias) mediante un diseño randomizado. Ninguna de las fincas evaluadas aplicó correctamente la práctica de la inseminación artificial, errores notorios fueron: exceso de tiempo durante la extracción de la pajilla, descongelación en la región axilar y no combinación correcta entre tiempo y temperatura. Los resultados evidenciaron diferencia significativa (P&lt,0.05) por efecto de la raza para la integridad y resistencia de las membranas espermáticas, para la integridad de las membranas por efecto de los tratamientos cuando la pajilla se descongelo a temperatura corporal en la región axilar y para la integridad de la membrana acrosomal cuando la extracción de la pajilla se realizó en forma incorrecta. El semen de la raza Holstein evidencia una ligera tendencia a ser más resistente que el de la raza Pardo Suizo

Visualization and analysis of cellular & Twitter data using qgis

The study is to understand individual presence and movement in Friuli Venezia Giulia region. It is important for tourism planning, hazard management, business marketing, implementing government lifetime policies and benefit. The aim of this study is achieved by advanced web 2.0 applications. We need real time and geo-located data to monitor the inflow of tourist and to come up with effective promoting and benefiting plans for tourism, the evacuation and mitigation strategies during hazards to protect social life and environment with less infrastructure damage, marketing plans for advertising or selling of products. Despite wide spread success in predicting specific aspects of human behavior by social media information, a little attention is given to twitter and cell phone data. Accessibility to detailed human movements with fine spatial and temporal granularity is challenging due to confidentiality and safety reasons. With rapid development of web2.0 applications people can post about events, share opinion and emotions online. Using twitter data, how short term travelers, such as tourists, can be recognized and how their travel pattern can be analyzed. Study of finding tourist dynamics such as arriving and outgoing of tourist, sum of trips, sum of days and night spent, number of unique visitors, country of residence, main destination, secondary destination, transits pass through, repeat visits are achieved using CDR (call detail records) and DDR (data detail records)

Healthcare-Associated Pneumonia: Don't Forget About Respiratory Viruses!

Introduction: Healthcare-associated infections are an important cause of morbidity and mortality, are among the most common adverse events in healthcare, and of them, pneumonia is the most commonly reported. Our objective was to evaluate the incidence and clinical outcome of respiratory viruses in hospital-acquired pneumonia (HAP).Methods: This was a prospective cohort study, include patients aged between 0 and 18 who fulfilled Centers for Diseases Control and Prevention (CDC) criteria for HAP. Demographic and clinical data were obtained, and a nasopharyngeal swab specimen was taken for the detection of respiratory viruses. All included patients were monitored until discharge to collect data on the need for mechanical ventilation, intensive care unit (ICU) admission, and mortality. All-cause 30-day mortality was also ascertained.Results: Four thousand three hundred twenty-seven patients were followed for 42,658 patient-days and 5,150 ventilator-days. Eighty-eight patients (2.03%) met the CDC criteria for HAP, 63 patients were included, and clinical and epidemiological characteristics showed no statistically significant differences between patients with virus associated healthcare-associated pneumonia (VAHAP) and those with non-viral healthcare-associated pneumonia (NVHAP). At least one respiratory virus was detected in 65% [95% CI (53–77)] of episodes of HAP, with a single viral pathogen observed in 53.9% and coinfection with 2 viruses in 11.1% of cases. The outcome in terms of ICU admission, mechanical ventilation and the 30-day mortality did not show a significant difference between groups.Conclusions: In two-thirds of the patients a respiratory virus was identified. There was no difference in mortality or the rest of the clinical outcome variables. About half of the patients required mechanical ventilation and 10% died, which emphasizes the importance of considering these pathogens in nosocomial infections, since their identification can influence the decrease in hospital costs and be taken into account in infection control policies

Two functional variants of IRF5 influence the development of macular edema in patients with non-anterior uveitis.

Objective Interferon (IFN) signaling plays a crucial role in autoimmunity. Genetic variation in interferon regulatory factor 5 (IRF5), a major regulator of the type I interferon induction, has been associated with risk of developing several autoimmune diseases. In the current study we aimed to evaluate whether three sets of correlated IRF5 genetic variants, independently associated with SLE and with different functional roles, are involved in uveitis susceptibility and its clinical subphenotypes. Methods Three IRF5 polymorphisms, rs2004640, rs2070197 and rs10954213, representative of each group, were genotyped using TaqMan® allelic discrimination assays in a total of 263 non-anterior uveitis patients and 724 healthy controls of Spanish origin. Results A clear association between two of the three analyzed genetic variants, rs2004640 and rs10954213, and the absence of macular edema was observed in the case/control analysis (PFDR=5.07E-03, OR=1.48, CI 95%=1.14-1.92 and PFDR=3.37E-03, OR=1.54, CI 95%=1.19-2.01, respectively). Consistently, the subphenotype analysis accordingly with the presence/absence of this clinical condition also reached statistical significance (rs2004640: P=0.037, OR=0.69, CI 95%=0.48-0.98; rs10954213: P=0.030, OR=0.67, CI 95%=0.47-0.96), thus suggesting that both IRF5 genetic variants are specifically associated with the lack of macular edema in uveitis patients. Conclusion Our results clearly showed for the first time that two functional genetic variants of IRF5 may play a role in the development of macular edema in non-anterior uveitis patients. Identifying genetic markers for macular edema could lead to the possibility of developing novel treatments or preventive therapies

New insights into the genetic component of non-infectious uveitis through an Immunochip strategy

Background: Large-scale genetic studies have reported several loci associated with specific disorders involving uveitis. Our aim was to identify genetic risk factors that might predispose to uveitis per se, independent of the clinical diagnosis, by performing a dense genotyping of immune-related loci. Methods: 613 cases and 3693 unaffected controls from three European case/control sets were genotyped using the Immunochip array. Only patients with non-infectious non-anterior uveitis and without systemic features were selected. To perform a more comprehensive analysis of the human leucocyte antigen (HLA) region, SNPs, classical alleles and polymorphic amino acid variants were obtained via imputation. A meta-analysis combining the three case/control sets was conducted by the inverse variance method. Results: The highest peak belonged to the HLA region. A more detailed analysis of this signal evidenced a strong association between the classical allele HLA-A*2902 and birdshot chorioretinopathy (p=3.21E-35, OR=50.95). An omnibus test yielded HLA-A 62 and 63 as relevant amino acid positions for this disease. In patients with intermediate and posterior uveitis, the strongest associations belonged to the rs7197 polymorphism, within HLA-DRA (p=2.07E-11, OR=1.99), and the HLA-DR15 haplotype (DRB1*1501: p=1.16E-10, OR=2.08; DQA1*0102: p=4.37E-09, OR=1.77; DQB1*0602: p=7.26E-10, OR=2.02). Outside the HLA region, the MAP4K4/IL1R2 locus reached statistical significance (rs7608679: p=8.38E-07, OR=1.42). Suggestive associations were found at five other loci. Conclusions: We have further interrogated the association between the HLA region and non-infectious non-anterior uveitis. In addition, we have identified a new non-HLA susceptibility factor and proposed additional risk loci with putative roles in this complex condition

Acqua e terra nei paesaggi monastici. Gestione, cura e costruzione del suolo

I testi compresi nel volume trattano del tema dell’acqua e della terra, elementi essenziali alla vita dell’umanità, simboli ancestrali di molte culture e al centro della Creazione nel racconto biblico. Nelle scritture e nei testi esegetici l’acqua è assimilata alla forza vivificante della Parola, e come tale diviene protagonista nell’iconografia cristiana attraverso i secoli, a partire dal medioevo. Si indagano le funzioni svolte dai monaci benedettini nell’organizzazione del territorio attraverso opere di bonifica, la realizzazione di sistemi idrici, un miglioramento nella conservazione dei frutti delle culture agricole nelle architetture di produzione. Altri saggi esplorano importanti aspetti della questione ambientale, al di fuori del mondo monastico, dall’età medievale fino ai nostri giorni, aprendosi al confronto con tradizioni diverse, ad esempio l’uso dei terrazzamenti in Cina o il richiamo a problemi pressanti quali quelli del rischio idrogeologico ad Algeri o in Italia, che può compromettere quell’armonia composta frutto di equilibrate scelte consapevoli, oggi sempre più minacciata da una crescita disordinata e aggressiva

Blood neutrophils from children with COVID-19 exhibit both inflammatory and anti-inflammatory markers

Background: Perhaps reflecting that children with COVID-19 rarely exhibit severe respiratory symptoms and often remain asymptomatic, little attention has been paid to explore the immune response in pediatric COVID-19. Here, we analyzed the phenotype and function of circulating neutrophils from children with COVID-19. Methods: An observational study including 182 children with COVID-19, 21 children with multisystem inflammatory syndrome (MIS-C), and 40 healthy children was performed in Buenos Aires, Argentina. Neutrophil phenotype was analyzed by flow cytometry in blood samples. Cytokine production, plasma levels of IgG antibodies directed to the spike protein of SARS-CoV-2 and citrullinated histone H3 were measured by ELISA. Cell-free DNA was quantified by fluorometry. Findings: Compared with healthy controls, neutrophils from children with COVID-19 showed a lower expression of CD11b, CD66b, and L-selectin but a higher expression of the activation markers HLA-DR, CD64 and PECAM-1 and the inhibitory receptors LAIR-1 and PD-L1. No differences in the production of cytokines and NETs were observed. Interestingly, the expression of CD64 in neutrophils and the serum concentration of IgG antibodies directed to the spike protein of SARS-CoV-2 distinguished asymptomatic from mild and moderate COVID-19. Interpretation: Acute lung injury is a prominent feature of severe COVID-19 in adults. A low expression of adhesion molecules together with a high expression of inhibitory receptors in neutrophils from children with COVID-19 might prevent tissue infiltration by neutrophils preserving lung function.Fil: Seery, Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Raiden, Silvina Claudia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Algieri, Silvia C.. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Grisolía, Nicolás A.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Filippo, Daniela. Hospital Municipal Diego Thompson; ArgentinaFil: De Carli, Norberto. Clinica del Niño de Quilmes; ArgentinaFil: Di Lalla, Sandra. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Cairoli, Héctor. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Chiolo, María J.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Meregalli, Claudia N.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Gimenez, Lorena I.. Hospital Municipal Diego Thompson; ArgentinaFil: Gregorio, Gabriela. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Sarli, Mariam. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Alcalde, Ana L.. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Davenport, Carolina. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Bruera, María J.. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Simaz, Nancy. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Pérez, Mariela F.. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Nivela, Valeria. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Bayle, Carola. Hospital Nacional Profesor Alejandro Posadas.; ArgentinaFil: Tuccillo, Patricia. Ministerio de Defensa. Armada Argentina. Hospital Naval Buenos Aires Cirujano Mayor Dr. Pedro Mallo; ArgentinaFil: Agosta, María T.. Ministerio de Defensa. Armada Argentina. Hospital Naval Buenos Aires Cirujano Mayor Dr. Pedro Mallo; ArgentinaFil: Pérez, Hernán. Ministerio de Defensa. Armada Argentina. Hospital Naval Buenos Aires Cirujano Mayor Dr. Pedro Mallo; ArgentinaFil: Villa Nova, Susana. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: Suárez, Patricia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: Takata, Eugenia M.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: García, Mariela. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: Lattner, Jorge. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: Rolón, María J.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: Coll, Patricia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: Sananez, Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Holgado, María Pía. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Ferrero, Fernando. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Geffner, Jorge Raúl. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Arruvito, Maria Lourdes. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentin