203 research outputs found
Analisi dei materiali, progettazione e dimensionamento dell'impianto fotovoltaico in un edificio bioclimatico a Rosignano Solvay
Lo scopo di questo lavoro è focalizzare l’attenzione sulle moderne tecnologie e sugli accorgimenti costruttivi per il risparmio energetico.
Ho preso parte al progetto di un edificio da realizzare a Rosignano Solvay, con valenza volutamente dimostrativa dei canoni della bioedilizia e dell’efficienza energetica. Inizialmente sono stati analizzati i materiali isolanti da poter utilizzare nella stratificazione del muro, in base alle loro caratteristiche coibentanti ma anche ecologiche. Ho calcolato, mediante l’utilizzo di software idonei, le dispersioni di calore che gli isolanti scelti riescono a minimizzare, e successivamente la prestazione energetica dell’edificio, tenendo conto dei vari impianti a energie rinnovabili ivi collocati. La fase successiva del lavoro è stata il dimensionamento dell’impianto fotovoltaico
Alberdi y Esquiú: dos hombres y una constitución
La idea central de este trabajo es analizar el pensamiento de dos intelectuales fundamentales al momento de la organización nacional en Argentina. A partir del análisis de Las Bases de Juan Bautista Alberdi y los Sermones Patrióticos de Fray Mamerto Esquiú, se advierten diferencias -algunas muy evidentes e importantes y otras no tanto-, pero también que ambos buscaron privilegiar caminos de entendimiento y pacificación, por sobre sus preferencias ideológicasy deseos más Ãntimos, para lograr superar los problemas que habÃan generado guerras civiles desde la independencia y la imposibilidad de sanción de una constitución
The innovative approach of Biomimetica and its application to sustainable retrofitting of existing buildings
In recent decades, elements and technological systems inspired by the natural world have become more widespread in architecture and construction industry, in order to improve the energy efficiency and thermal behavior of buildings. The best known example are green facades, increasingly used to improve the energy efficiency of new buildings and the bioclimatic comfort of urban settlements. Through biomimetic studies, innovative solutions are being proposed, from the use of living biological systems (e.g. bio-reactive facades) for climate control to new natural materials (e.g. metal-sensitive wooden sheets) that react directly to external factors such as light, heat, humidity, opening and closing without the use of energy or mechanical aids. All these systems contribute to improving the energy efficiency of both buildings and the urban system in which they are located. The contribution aims to examine technological solutions based on biomimetic methodology, to assess their applicability in the retrofitting of existing buildings
Authentication of Argan (Argania spinosa L.) oil using novel DNA-based approaches: detection of olive and soybean oils as potential adulterants
Argan oil is a traditional product obtained from the fruits of the argan tree (Argania spinosa L.), which is endemic only to Morocco. It is commercialized worldwide as cosmetic and food-grade argan oil, attaining very high prices in the international market. Therefore, argan oil is very prone to adulteration with cheaper vegetable oils. The present work aims at developing novel real-time PCR approaches to detect olive and soybean oils as potential adulterants, as well as ascertain the presence of argan oil. The ITS region, matK and lectin genes were the targeted markers, allowing to detect argan, olive and soybean DNA down to 0.01 pg, 0.1 pg and 3.2 pg, respectively, with real-time PCR. Moreover, to propose practical quantitative methods, two calibrant models were developed using the normalized ΔCq method to estimate potential adulterations of argan oil with olive or soybean oils. The results allowed for the detection and quantification of olive and soybean oils within 50–1% and 25–1%, respectively, both in argan oil. Both approaches provided acceptable performance parameters and accurate determinations, as proven by their applicability to blind mixtures. Herein, new qualitative and quantitative PCR assays are proposed for the first time as reliable and high-throughput tools to authenticate and valorize argan oil.This work was supported by the FCT (Fundação para a Ciência e Tecnologia) through
projects FCT/CNRST (Portugal/Morocco) (FCT/6460/6/6/2017/S) and the strategic funding of
UIDB/50006/2020 | UIDP/50006/2020. This work was also funded by the European Union (EU)
through the European Regional Development Fund (FEDER funds through NORTE-01-0145-FEDER-
000052) and the project SYSTEMIC (Knowledge Hub on Food and Nutrition Security, ERA-Net
Cofund ERA-HDHL no. 696300). J. Costa and I. Mafra thank the FCT for funding through the
Individual Call to Scientific Employment Stimulus (2021.03583.CEECIND/CP1662/CT0012 and
2021.03670.CEECIND/CP1662/CT0011, respectively). L. Grazina is grateful to the FCT for the grant
(SFRH/BD/132462/2017) financed by POPH-QREN (subsidized by FSE and MCTES). The authors are grateful to the Groupement des Coopératives Targanine for
supplying the argan oil sample. J.S. Amaral is grateful to the FCT for financial support through
national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 e UIDP/00690/2020) and
SusTEC (LA/P/0007/2020).info:eu-repo/semantics/publishedVersio
Assessment of electrical effects of ohmic heating on structural and immunoreactivity properties of bovine betalactoglobulin
This study was supported by the Portuguese Foundation for Science and Technology (FCT) under
the scope of the strategic funding of UID/BIO/04469/2019 unit and BioTecNorte operation
(NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under
the scope of Norte2020 - Programa Operacional Regional do Norte. This work was also
supported by FCT and POCI through project AlleRiskAssess (POCI-01-0145-FEDER-031720 –
PTDC/BAA-AGR/31720/2017). C. Villa is grateful to FCT grant (PD/BD/114576/2016) financed by
POPH-QREN (subsidised by FSE and MCTES). R. Rodrigues is grateful to FCT grant with reference
SFRH/BD/110723/2015.info:eu-repo/semantics/publishedVersio
39 Hints to Facilitate the Use of Semantics for Data on Agriculture and Nutrition
In this paper, we report on the outputs and adoption of the Agrisemantics
Working Group of the Research Data Alliance (RDA), consisting of a set of
recommendations to facilitate the adoption of semantic technologies and methods
for the purpose of data interoperability in the field of agriculture and
nutrition. From 2016 to 2019, the group gathered researchers and practitioners
at the crossing point between information technology and agricultural science,
to study all aspects in the life cycle of semantic resources:
conceptualization, edition, sharing, standardization, services, alignment, long
term support. First, the working group realized a landscape study, a study of
the uses of semantics in agrifood, then collected use cases for the
exploitation of semantics resources-a generic term to encompass vocabularies,
terminologies, thesauri, ontologies. The resulting requirements were
synthesized into 39 "hints" for users and developers of semantic resources, and
providers of semantic resource services. We believe adopting these
recommendations will engage agrifood sciences in a necessary transition to
leverage data production, sharing and reuse and the adoption of the FAIR data
principles. The paper includes examples of adoption of those requirements, and
a discussion of their contribution to the field of data science
Representativeness in randomised clinical trials supporting acute coronary syndrome guidelines.
This project has received funding to cover the electronic case report form from the Balearic Society of Cardiology (Sociedad Balear
CardiologÃa) through the ‘Bernat Nadal Ginard’ grant. Open access
has been partly granted by the LIBERI PROGRAM 2023 of the Health
Research Institute of the Balearic Islands (IdISBa).AIMS
Clinical practice guidelines (CPGs) are published to guide the management of acute coronary syndrome (ACS). We aimed to critically appraise the representativeness and standard of care of randomised clinical trials (RCTs) supporting CPGs for ACS.
METHODS AND RESULTS
American and European CPGs for ST- and non-ST-elevation ACS were screened to extract all references (n = 2128) and recommendations (n = 600). Among the 407 primary publications of RCTs (19.1%), there were 52.6% and 73.2% recruiting patients in North America and Europe, respectively, whereas other regions were largely underrepresented (e.g., 25.3% RCTs recruited in Asia). There was 68.6% RCTs enrolling patient with ACS, whereas the remaining 31.4% did not enroll any patient with ACS. There was underrepresentation of some important subgroups, including elderly, female (29.9%) and non-white patients (<20%). The incidence and type of reperfusion reported in these RCTs were not reflective of current clinical practice (the percentage of patients who underwent percutaneous coronary intervention (PCI) among all RCTs was 42.7%; whereas for ST-Elevation Myocardial Infarction patients, the number of participants who underwent fibrinolysis was 3.3-fold higher than those who underwent primary PCI). All-cause mortality in these RCTs was 11.9% in RCTs with a follow-up ≤1 year.
CONCLUSION
RCTs supporting CPGs for ACS are not fully representative of the diversity of the ACS population and their current standard of care. While some of these issues with representativeness may be explained by how evidence has been accrued over time, efforts should be made by trialists to ensure that the evidence supporting CPGs is representative of the wider ACS population.S
Faecal calprotectin and ultrasonography as non-invasive screening tools for detecting colorectal polyps in children with sporadic rectal bleeding. a prospective study
Background: Colorectal polyps are reported in 6,1% of paediatric colonoscopies and in 12% of those performed for
lower gastrointestinal bleeding. Although colonoscopy is widely used in paediatric patients, it requires bowel
preparation and general anaesthesia or deep sedation, and in rare cases, it can cause complications. Non-invasive
screening techniques able to predict polyps in children with isolated and sporadic rectal bleeding may play a key
role in the selection of patients needing colonoscopy.
Methods: We enrolled all children undergoing colonoscopy for isolated and sporadic rectal bleeding to determine
the diagnostic accuracy of faecal calprotectin, ultrasonography (US) and digital rectal examination as diagnostic
methods for screening colorectal polyps.
Results: A total of 26 of 59 enrolled patients (44.1%) had colonic polyps, one patient had multiple polyps, and 23%
of children had polyps proximal to the splenic flexure. The diagnostic accuracy of faecal calprotectin for detecting
colorectal polyps was 96.6%, with a sensitivity of 100%. False-positive faecal calprotectin was shown in 2 patients
with non-steroidal anti-inflammatory drug-related lesions. The diagnostic accuracy of ultrasound was 77.9%. Polyps
not seen with ultrasound tended to be relatively smaller (1.5 vs 2.3, p = 0.001) and located in the rectum. The
combined use of FC, US and digital rectal examination obtained a specificity and PPV of 100%.
Conclusions: FC combined with US and digital rectal examination is a good and promising non-invasive screening
test for detecting colorectal polyps in children with isolated and sporadic rectal bleeding
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