562 research outputs found
Quasi Switched Capacitor based integrated Boost Series Parallel Fly-back Converter for energy Storage Applications
711-715A quasi-Switched Capacitor technique (QSC) is used to control the switch in Interconnected Boost Series Parallel Fly-Back Converter (IBSPFC). The QSC based IBSPFC does not require any snubber circuits for all the MOSFET switches presented at primary and secondary side and power can also be transferred even if one the winding gets damage. The primary side winding of the fly-back transformer is coupled in series across with bulk capacitor to minimize switch voltage stress and the secondary winding of the 1:1 fly-back transformer is coupled with dc voltage source, three switches and capacitor which forms a Quasi switched capacitor technique. Working techniques of quasi-switched capacitor with IBSPFC have been introduced. A 75v input, 100v output and DC-DC isolated Converter switching at frequency of 100 kHz is modeled using FPGA SPARTAN6LX9 and experimental results have been presented
STANDARDIZATION IN VITRO ANTIOXIDANT ACTIVITY AND BRINE SHRIMP LETHALITY OF A POLYHERBAL FORMULATION
Shakti drops an Ayurvedic polyherbal formulation is an effective medicine for immuno modulatory activity. The formulation was prepared in the laboratory with authenticated organic plant drugs. The standardization procedure was conducted on the basis of physicochemical parameters and antimicrobial studies as directed by Ayurvedic formulary of India. Antioxidant activity is further performed based on its prescribed dose in three In-vitro antioxidant models. Physical characters remained unaltered throughout study, In antimicrobial activity total aerobic count was found to be 18×101 CFU/mL and total fungal count was found to be <10 CFU/mL. It is devoid of all tested microorganism i.e. Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Escherichia coli tested. In antioxidant activity the results of the study suggest that the Shiakti drops has potent antioxidant and free radical scavenging activity justifying its use in Rasayana
3D Modelling & Detailing of Silumin Piston With Static Analysis
Piston is the part of engine which converts heat and pressure energy liberated by fuel combustion into mechanical work. Engine piston is the most complex component among the automotives. Weight reduction has been gaining importance in automobile field because reducing in weight decreases load on the engine. As we all Know that Piston is made of Aluminium Alloy Such that its weight is less. The automobile industry has shown increased interest in replacing the Piston with the material having high strength to weight ratio. Therefore the objective of this project is to present a general study on the performance comparison of Silumin Piston and Aluminium Alloy Piston. Dimensions and specifications used in modelling are collected from the actual Piston of Hero-Honda Splendor Bike. The analysis is carried out in the commercially available software Solid Work
Cultural Health Moments: A Search Analysis During Times of Heightened Awareness to Identify Potential Interception Points with Digital Health Consumers
Year after year whenever someone who is considered “high profile” discovers that they have some sort of sickness or if they pass away due to a sickness, there seems to be a heightened interest in that person. At the same time however, there is a heightened awareness of the type of sickness that the person had. Finding the moments in which there is a heightened sense of awareness towards a specific topic can be something of high value to various agencies and organizations. The objective of this study was to explore the moments in which people start to do some initial search queries when there is a high-profile health moment. Once it is understood when this moment occurs, further research can be done to understand where the search behavior shifts to searches of awareness, signs, symptoms, and introspection over time
Decision Making Behaviour of Fisherwomen of Dakshina Kannada District of Karnataka - An Empirical Analysis
Among the different sectors of the Indian economy
where women contribute significantly, fisheries
sector occupies a prime place. Out of the total
fisherfolk population of Karnataka, comprising
1 67 429, around 23 000 fisherwomen are actively
involved in fisheries related activities such as
marketing of fish, net making/repairing, curing/
processing, peeling, labour and other miscellaneous
activities. Though, studies have captured the pivotal
role played by fisherwomen in income generation
for their families, the decision making behavior, a
key parameter of their empowerment status, remains
an unexplored area. The present study deals
with the areas of decision making in which
fisherwomen are involved and the influence of
socio-economic status on their decision making
behavior. The study was undertaken in three
selected villages in Dakshina Kannada district of
Karnataka using multi stage random sampling
method. From the findings, it was observed that,
84.16% of female fresh fish vendors had medium
level of decision making behaviour. Fisherwomen
were observed to be the sole and independent
decision makers with respect to all aspects of fish
marketing such as source of fish purchase, rate and
quantity to be purchased, transportation, quantity of
ice to be used, selling price, time of fish sales,
purchasing and hiring of equipment and getting and
repaying credits
In-vitro study of formulation and evaluation of nanosuspension of tamoxifen
Background: Nanosuspension technology has been developed as a promising candidate for efficient delivery of hydrophobic drugs. It could maintain the required crystalline state of the drug with reduced particle size, leading to an increased reporting on dissolution rate and therefore improved bioavailability.Methods: In this paper, we report on the preparation of Tamoxifen nanosuspension by high-pressure homogenization (HPH). The aim is to obtain a stable nanosuspension with an increased drug saturation solubility and dissolution velocity. The morphology and particle size distribution of the modified nanosuspensions were characterized by the means of several analyses that included: transmission electron microscopy (TEM), polarized light microscopy (PLM), scanning electron microscopy, differential scanning calorimetry (DSC) and powder X- ray diffractometry (XRD).Results: HPH was employed to produce aqueous drug nanosuspensions with fine solubility and dissolution properties, which render the produced particles stable up to one month. In addition, the prepared nanosuspensions possessed a high drug-loading efficiency (10%). The recoded zeta potential values (≈ -27 mV) indicated that the prepared nanosuspensions possess a higher degree of long-term stability. TEM data showed narrow size distribution with average size 322.7 nm. Morphologically, as indicated from results, the produced nanosuspensions have a homogenous distribution even after redispersion, indicating the stability of the product.Conclusions: It was possible to obtain Tamoxifen nanosuspensions with fine solubility and dissolution properties. Nanosuspensions possessed a high drug- loading (10%), which could reduce the dosage administration and gastrointestinal side effects. HPH can be employed to produce aqueous drug nanosuspensions that are stable up to one month. Aqueous nanosuspension can be converted to dry nanocrystals by lyophilization which offer superior physicochemical properties
Genetic affinities among the lower castes and tribal groups of India: inference from Y chromosome and mitochondrial DNA
BACKGROUND: India is a country with enormous social and cultural diversity due to its positioning on the crossroads of many historic and pre-historic human migrations. The hierarchical caste system in the Hindu society dominates the social structure of the Indian populations. The origin of the caste system in India is a matter of debate with many linguists and anthropologists suggesting that it began with the arrival of Indo-European speakers from Central Asia about 3500 years ago. Previous genetic studies based on Indian populations failed to achieve a consensus in this regard. We analysed the Y-chromosome and mitochondrial DNA of three tribal populations of southern India, compared the results with available data from the Indian subcontinent and tried to reconstruct the evolutionary history of Indian caste and tribal populations. RESULTS: No significant difference was observed in the mitochondrial DNA between Indian tribal and caste populations, except for the presence of a higher frequency of west Eurasian-specific haplogroups in the higher castes, mostly in the north western part of India. On the other hand, the study of the Indian Y lineages revealed distinct distribution patterns among caste and tribal populations. The paternal lineages of Indian lower castes showed significantly closer affinity to the tribal populations than to the upper castes. The frequencies of deep-rooted Y haplogroups such as M89, M52, and M95 were higher in the lower castes and tribes, compared to the upper castes. CONCLUSION: The present study suggests that the vast majority (>98%) of the Indian maternal gene pool, consisting of Indio-European and Dravidian speakers, is genetically more or less uniform. Invasions after the late Pleistocene settlement might have been mostly male-mediated. However, Y-SNP data provides compelling genetic evidence for a tribal origin of the lower caste populations in the subcontinent. Lower caste groups might have originated with the hierarchical divisions that arose within the tribal groups with the spread of Neolithic agriculturalists, much earlier than the arrival of Aryan speakers. The Indo-Europeans established themselves as upper castes among this already developed caste-like class structure within the tribes
Efficacy of calcium sodium phosphosilicate containing dentifrice in reducing dentin hypersensitivity compared to other dentifrices with dentin tubule occluding molecules: A systematic review
Purpose: To assess the effectiveness of calcium sodium phosphosilicate in reducing dentin hypersensitivity compared to other dentin tubule occluding molecules.
Methods: A structured research question was formulated, and an electronic search of available literature was carried out via PubMed, Google Scholar, and Scopus. A hand search as well as a gray literature search were also carried out. The search produced a total of 67 articles. Of these, only eight articles were eligible to be included in our review. Risk of bias and study quality were checked using Cochrane tool. The review was registered in The International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD42018096200.
Results: The results show a reduction in dentin hypersensitivity with calcium sodium phosphosilicate compared to many other molecules. However, nanohydroxyapatite showed a better desensitizing effect compared to Novamin.
Conclusion: According to the available evidence, 5 % calcium sodium phosphosilicate containing toothpaste is more effective reducing dentin hypersensitivity compared to many other dentinal tubule occluding molecules
MECHANICAL BEHAVIOR OF BALL BURNISHING ON COMPOSITE MATERIAL
Burnishing is a chip less finishing method which employs a rolling tool pressed against the work piece for achieving of the surface layer. Ball burnishing process is largely considered in industrial cases in order to restructure surface characteristic. Ball burnishing process is employed on 100% aluminum alloy and aluminum (99%, 98%) with zirconium (+1%, +2%) work piece for current study. In this thesis, work the effect of burnishing parameter like speed, and feed and the number of passes is going to be examined on the surface quality and its wearing characteristics of aluminum with zirconium (+1%, +2%). For this experimental work, I utilize Taylor Hobson for measuring surface roughness and Brinell hardness for measuring surface hardness. In this thesis force and number of passes of tool are kept constant. The main aim of this thesis is to compare surface roughness and surface hardness values on 100% aluminum alloy and aluminum (99%, 98%) with zirconium (+1%, +2%) work piec
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