143 research outputs found
Evaluation of HBV-Like circulation in wild and farm animals from Brazil and Uruguay
The origin of the hepatitis B virus is a subject of wide deliberation among researchers. As a result, increasing academic interest has focused on the spread of the virus in different animal species. However, the sources of viral infection for many of these animals are unknown since transmission may occur from animal to animal, human to human, animal to human, and human to animal. The aim of this study was to evaluate hepadnavirus circulation in wild and farm animals (including animals raised under wild or free conditions) from different sites in Brazil and Uruguay using serological and molecular tools. A total of 487 domestic wild and farm animals were screened for hepatitis B virus (HBV) serological markers and tested via quantitative and qualitative polymerase chain reaction (PCR) to detect viral DNA. We report evidence of HBsAg (surface antigen of HBV) and total anti-HBc (HBV core antigen) markers as well as low-copy hepadnavirus DNA among domestic and wild animals. According to our results, which were confirmed by partial genome sequencing, as the proximity between humans and animals increases, the potential for pathogen dispersal also increases. A wider knowledge and understanding of reverse zoonoses should be sought for an effective One Health response
Search for the doubly heavy baryon decaying to
A first search for the
decay is performed by the LHCb experiment with a data sample of proton-proton
collisions, corresponding to an integrated luminosity of
recorded at centre-of-mass energies of 7, 8, and . Two peaking structures are seen with a local (global) significance of
and standard deviations at masses of
and , respectively. Upper limits are set on the baryon
production cross-section times the branching fraction relative to that of the
decay at centre-of-mass energies of 8 and
, in the and in the
rapidity and transverse-momentum ranges from 2.0 to 4.5 and 0 to
, respectively. Upper limits are presented
as a function of the mass and lifetime.Comment: All figures and tables, along with machine-readable versions and any
supplementary material and additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-005.html (LHCb
public pages
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